公开(公告)号：US06398705B1

公开(公告)日：2002-06-04

申请号：US09661131

申请日：2000-09-13

申请人： Manfred Grumberg ,  Oren Zinder ,  James W. Winkelman ,  Jacob Schreibman

发明人： Manfred Grumberg ,  Oren Zinder ,  James W. Winkelman ,  Jacob Schreibman

IPC分类号： B04B502

CPC分类号： B04B5/0414 ,  G01N33/491

摘要： The method of rapidly separating plasma or serum from red blood cells comprising the steps of mounting a pair of spaced apart tubes coaxially related to one another head-to-head with a sharp-ended hollow needle disposed generally along the tube axes and between them, arranging the tubes in a vertical position one above the other in a centrifuge with the tubes closed with self-sealing stoppers, providing a partial vacuum in the upper tube, rotating the tubes at high speed about an axis parallel to and spaced from the axis of the tubes and needle, after separation of the red blood cells from the plasma and serum causing the tubes while still being rotated to be moved relative to one another such as to cause the needle to enter both tubes through the stoppers, separating the tubes while still being rotated by the centrifuge whereby to remove the needle from both tubes.

摘要翻译： 从红细胞中快速分离血浆或血清的方法包括以下步骤：将一对间隔开的管以相对于彼此头对头的方式同轴地相连，其中所述尖头端中空针通常沿着管轴和它们之间布置， 将管子放置在离心机中的一个垂直位置上，其中管子用自密封塞子封闭，在上管中提供部分真空，使管子以高速度绕与轴线平行并与其间隔开的轴线 管和针之后，红细胞从等离子体和血清分离出来，导致管子同时仍然被旋转以相对于彼此移动，以使针头通过塞子进入两个管，同时分离管 由离心机旋转，从而从两个管中取出针头。

公开(公告)号：US6132353A

公开(公告)日：2000-10-17

申请号：US897420

申请日：1997-07-21

申请人： James W. Winkelman ,  Oren Zinder ,  Manfred Grumberg ,  Jacob Schreibman

发明人： James W. Winkelman ,  Oren Zinder ,  Manfred Grumberg ,  Jacob Schreibman

IPC分类号： B04B5/02 ,  B04B5/04 ,  G01N33/49

CPC分类号： B04B5/0414 ,  G01N33/491

摘要： Red cells are separated from plasma or serum of whole blood by arranging an evacuated tube sealed by a self-sealing stopper above and preferably coaxial with a tube containing a blood sample and sealed by a self-sealing stopper. A hollow double ended needle is held by a fixture and is disposed between and coaxial with the tubes and the tubes are placed in the fixture in a vertical position in a centrifuge and rotated about and spaced from an axis parallel to the axis of the tubes and needle. After the red cells are separated from the serum and/or plasma the tubes are pushed toward one another so that the needle penetrates both stoppers and the serum and/or plasma is drawn into the upper tube. The tubes and needle are separated while still being rotated so that the whole blood components are separated as required.

摘要翻译： 将红细胞与全血的血浆或血清分开，通过将自封闭塞子密封的真空管布置在上面并且优选地与含有血液样品的管同轴并由自密封塞密封。 空心双头针由固定器固定并且设置在管之间并且与管同轴，并且管在离心机中处于垂直位置并且与平行于管的轴线的轴线旋转并且与其平行的轴线间隔开，并且 针。 在从血清和/或等离子体分离红细胞后，将管彼此推动，使得针穿透两个塞子，将血清和/或血浆拉入上管。 管和针在仍然旋转的同时分离，使得全部血液成分根据需要分离。

公开(公告)号：US06905453B2

公开(公告)日：2005-06-14

申请号：US10352869

申请日：2003-01-29

申请人： Manfred Grumberg ,  Oren Zinder

发明人： Manfred Grumberg ,  Oren Zinder

IPC分类号： B01L3/00 ,  B01L3/14 ,  B04B5/04 ,  B04B7/08 ,  G01N33/49 ,  G01N35/00 ,  B04B5/02

CPC分类号： B04B7/08 ,  B01L3/502 ,  B01L3/5021 ,  B01L2200/026 ,  B01L2300/042 ,  B01L2300/0672 ,  B01L2400/0409 ,  B04B5/0414 ,  G01N33/491 ,  G01N2035/00495

摘要： A system for separating fluids by centrifuging, the system including: a rotor assembly for rotating in a centrifugation device, the rotor assembly including: (a) a first rotor for housing a plurality of tubes, each of the tubes containing a sample for separation by centrifuging; (b) a second rotor having a plurality of collection compartments, each compartment corresponding to a particular tube, and (c) a plurality of conduits, each corresponding to a particular compartment, each conduit for providing fluid communication, upon demand, between a particular tube and a particular compartment, so as to enable transfer of a fraction of each sample from the tubes to the compartments.

摘要翻译： 一种用于通过离心分离流体的系统，所述系统包括：用于在离心装置中旋转的转子组件，所述转子组件包括：（a）用于容纳多个管的第一转子，每个管包含用于分离的样品， 离心; （b）具有多个收集室的第二转子，每个隔室对应于特定的管，和（c）多个导管，每个导管对应于特定隔室，每个导管用于根据需要提供流体连通， 管和特定隔室，以便能够将每个样品的一部分从管转移到隔室。

公开(公告)号：US5391867A

公开(公告)日：1995-02-21

申请号：US021597

申请日：1993-02-24

申请人： Manfred Grumberg

发明人： Manfred Grumberg

IPC分类号： H04N1/14 ,  H04N1/191

CPC分类号： H04N1/1911 ,  H04N1/14

摘要： A wide format scanner moves a substrate to be scanned along a first axis and at a first predetermined speed, and moves a scanning head across the substrate obliquely with respect to the first axis at an angle and at a speed coordinated with the first predetermined speed so as to provide a scan trace perpendicular to the first axis.

摘要翻译： 宽格式扫描仪沿着第一轴线和第一预定速度移动要扫描的基板，并以相对于第一轴线倾斜地以与第一预定速度协调的速度倾斜地移动扫描头，从而 以提供垂直于第一轴的扫描迹线。

公开(公告)号：US06605092B2

公开(公告)日：2003-08-12

申请号：US09992019

申请日：2001-11-26

申请人： Manfred Grumberg ,  Zvi Laster

发明人： Manfred Grumberg ,  Zvi Laster

IPC分类号： A61B1756

CPC分类号： A61B17/17 ,  A61B17/1703 ,  A61B17/176 ,  A61C1/084

摘要： A system and a method for positioning a drill, having a drill bit with a central axis, for drilling a subsequent hole in a bone at a predetermined distance from and in a predetermined orientation in respect to a reference hole, is disclosed. The system comprises a reference insert, configured to be inserted into the reference hole, and adapted to establish a reference guideline, the reference guideline being of the predetermined orientation; and, an alignment mechanism, configured to be attached to the drill, the alignment mechanism adapted to be fixed at the predetermined distance from and parallel to the central axis of the drill bit, the alignment mechanism including an optical device for colinearly aligning an alignment axis of the alignment mechanism with the reference guideline.

摘要翻译： 公开了一种用于定位钻头的系统和方法，其具有具有中心轴线的钻头，用于相对于参考孔以预定方向在预定距离处以预定距离钻出骨中的随后的孔。 所述系统包括参考插入件，所述参考插入件被配置为插入到所述参考孔中，并且适于建立参考准则，所述参考准则具有所述预定取向; 以及配置为附接到所述钻头的对准机构，所述对准机构适于被固定在与所述钻头的中心轴线预定距离并且平行于所述钻头的中心轴线，所述对准机构包括用于将对准轴线 的对准机制与参考准则。