-
公开(公告)号：US20100120051A1
公开(公告)日：2010-05-13
申请号：US12686149
申请日：2010-01-12
IPC分类号： C12Q1/68
CPC分类号： C09B23/02 , C12Q1/6827 , G01N33/582 , Y10T436/143333 , C12Q2527/125 , C12Q2563/107
摘要： Cyanine dye compounds having a negatively charged substituent that are nucleic acid stains, particularly for fluorescent staining of DNA, including compounds having the formula wherein W forms one or two fused 5- or 6-membered aromatic rings, a has a value of 0 or 1, n has a value of 0, or 1, X is O, S, or Se, and D is a pyridinium, or quinolinium moiety, provided that the compound has at least one negatively charged substituent.
摘要翻译： 具有带负电荷的取代基的花青染料化合物，其特征在于DNA的荧光染色，包括具有下式的化合物，其中W形成一个或两个稠合的5-或6-元芳环，具有0或1的值 ，n为0或1，X为O，S或Se，D为吡啶鎓或喹啉鎓部分，条件是该化合物具有至少一个带负电荷的取代基。
-
公开(公告)号：US07446202B2
公开(公告)日：2008-11-04
申请号：US11005860
申请日：2004-12-06
IPC分类号： C07D215/38
CPC分类号： C09B23/02 , C12Q1/6827 , G01N33/582 , Y10T436/143333 , C12Q2527/125 , C12Q2563/107
摘要： Cyanine dye compounds having a negatively charged substituent that are nucleic acid stains, particularly for fluorescent staining of DNA, including compounds having the formula wherein W forms one or two fused 5- or 6-membered aromatic rings, a has a value of 0 or 1, n has a value of 0, or 1, X is O, S, or Se, and D is a pyridinium, or quinolinium moiety, provided that the compound has at least one negatively charged substituent.
摘要翻译： 具有带负电荷的取代基的花青染料化合物，其特征在于DNA的荧光染色，包括具有下式的化合物，其中W形成一个或两个稠合的5-或6-元芳环，具有0或1的值 ，n为0或1，X为O，S或Se，D为吡啶鎓或喹啉鎓部分，条件是该化合物具有至少一个带负电荷的取代基。
-
公开(公告)号：US20090047683A1
公开(公告)日：2009-02-19
申请号：US12240218
申请日：2008-09-29
CPC分类号： C09B23/02 , C12Q1/6827 , G01N33/582 , Y10T436/143333 , C12Q2527/125 , C12Q2563/107
摘要： Cyanine dye compounds having a negatively charged substituent that are nucleic acid stains, particularly for fluorescent staining of DNA, including compounds having the formula wherein W forms one or two fused 5- or 6-membered aromatic rings, α has a value of 0 or 1, n has a value of 0, or 1, X is O, S, or Se, and D is a pyridinium, or quinolinium moiety, provided that the compound has at least one negatively charged substituent.
摘要翻译： 具有带负电荷的取代基的花青染料化合物，特别是用于DNA的荧光染色的带负电荷的取代基，包括具有下式的化合物，其中W形成一个或两个稠合的5-或6-元芳环，α具有0或1的值 ，n为0或1，X为O，S或Se，D为吡啶鎓或喹啉鎓部分，条件是该化合物具有至少一个带负电荷的取代基。
-
公开(公告)号：US08999965B2
公开(公告)日：2015-04-07
申请号：US13126234
申请日：2009-10-20
申请人： Stephen Yue , Shih-Jung Huang , Jolene Bradford
发明人： Stephen Yue , Shih-Jung Huang , Jolene Bradford
CPC分类号： G01N33/52 , C07C225/36 , C07C237/10 , C07C2603/24 , C07D205/04 , C07D213/36 , C07D233/61 , C07D249/04 , C07D295/13 , C07D295/192 , C07H21/04 , C09B1/5165 , C12Q1/6816 , C12Q1/6841 , G01N21/6428 , G01N2021/6441
摘要： Disclosed are near IR emitting fluorescent compounds; methods of making and kits containing the described compounds; and their use in fluorescence-based detection of biological materials.
摘要翻译： 近红外发射荧光化合物; 制备方法和含有所述化合物的试剂盒; 以及它们在荧光检测生物材料中的应用。
-
5.发明授权Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use 有权对双链DNA具有高选择性的荧光化合物及其使用方法公开(公告)号：US07943777B2
公开(公告)日：2011-05-17
申请号：US12573809
申请日：2009-10-05
IPC分类号： C07D417/00 , C07D215/00 , C07D251/38
CPC分类号： G01N33/582 , C07D215/10 , C07D215/227 , C07D277/72 , C07D277/74 , C07D417/04 , C07D417/06 , C07D417/14 , C12Q1/6876 , G01N21/6428 , G01N21/6486 , G01N2021/6439 , G01N2201/06113 , Y10T436/143333
摘要： Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA.
摘要翻译： 公开了对RNA和单链DNA具有对双链DNA的高选择性的化合物。 化学化合物是在照射时变成荧光并与双链DNA相互作用的污渍，但在不存在双链DNA的情况下表现出减少的或没有荧光。 该化合物可用于各种生物学应用中，以定性或定量测定DNA，即使在RNA的存在下。
-
公开(公告)号：US20050214810A1
公开(公告)日：2005-09-29
申请号：US11005860
申请日：2004-12-06
申请人： Jason Dallwig , David Hagen , Shih-Jung Huang , Gerald Thomas , Stephen Yue
发明人： Jason Dallwig , David Hagen , Shih-Jung Huang , Gerald Thomas , Stephen Yue
CPC分类号： C09B23/02 , C12Q1/6827 , G01N33/582 , Y10T436/143333 , C12Q2527/125 , C12Q2563/107
摘要： Cyanine dye compounds having a negatively charged substituent that are nucleic acid stains, particularly for fluorescent staining of DNA, including compounds having the formula wherein W forms one or two fused 5- or 6-membered aromatic rings, a has a value of 0 or 1, n has a value of 0, or 1, X is O, S, or Se, and D is a pyridinium, or quinolinium moiety, provided that the compound has at least one negatively charged substituent.
摘要翻译： 具有带负电荷的取代基的花青染料化合物，其特征在于DNA的荧光染色，包括具有下式的化合物，其中W形成一个或两个稠合的5-或6-元芳环，具有0或1的值 ，n为0或1，X为O，S或Se，D为吡啶鎓或喹啉鎓部分，条件是该化合物具有至少一个带负电荷的取代基。
-
公开(公告)号：US07842811B2
公开(公告)日：2010-11-30
申请号：US12686149
申请日：2010-01-12
申请人： Jason Dallwig , David Hagen , Shih-Jung Huang , Gerald Thomas , Stephen Yue
发明人： Jason Dallwig , David Hagen , Shih-Jung Huang , Gerald Thomas , Stephen Yue
IPC分类号： C07D215/38 , C12Q1/68 , C07H21/02 , C07H21/04
CPC分类号： C09B23/02 , C12Q1/6827 , G01N33/582 , Y10T436/143333 , C12Q2527/125 , C12Q2563/107
摘要： Cyanine dye compounds having a negatively charged substituent that are nucleic acid stains, particularly for fluorescent staining of DNA, including compounds having the formula wherein W forms one or two fused 5- or 6-membered aromatic rings, α has a value of 0 or 1, n has a value of 0, or 1, X is O, S, or Se, and D is a pyridinium, or quinolinium moiety, provided that the compound has at least one negatively charged substituent.
摘要翻译： 具有带负电荷的取代基的花青染料化合物，其特征在于DNA的荧光染色，包括具有下式的化合物，其中W形成一个或两个稠合的5-或6-元芳环，α为0或1 ，n为0或1，X为O，S或Se，D为吡啶鎓或喹啉鎓部分，条件是该化合物具有至少一个带负电荷的取代基。
-
公开(公告)号：US07655409B2
公开(公告)日：2010-02-02
申请号：US12240218
申请日：2008-09-29
申请人： Jason Dallwig , David Hagen , Shih-Jung Huang , Gerald Thomas , Stephen Yue
发明人： Jason Dallwig , David Hagen , Shih-Jung Huang , Gerald Thomas , Stephen Yue
CPC分类号： C09B23/02 , C12Q1/6827 , G01N33/582 , Y10T436/143333 , C12Q2527/125 , C12Q2563/107
摘要： Cyanine dye compounds having a negatively charged substituent that are nucleic acid stains, particularly for fluorescent staining of DNA, including compounds having the formula wherein W forms one or two fused 5- or 6-membered aromatic rings, α has a value of 0 or 1, n has a value of 0, or 1, X is O, S, or Se, and D is a pyridinium, or quinolinium moiety, provided that the compound has at least one negatively charged substituent.
摘要翻译： 具有带负电荷的取代基的花青染料化合物，特别是用于DNA的荧光染色的带负电荷的取代基，包括具有下式的化合物，其中W形成一个或两个稠合的5-或6-元芳环，α具有0或1的值 ，n为0或1，X为O，S或Se，D为吡啶鎓或喹啉鎓部分，条件是该化合物具有至少一个带负电荷的取代基。
-
9.发明申请Flourescent chemical compounds having high selectivity for double standard DNA, and methods for their use 有权对双标准DNA具有高选择性的荧光化合物及其使用方法公开(公告)号：US20060263844A1
公开(公告)日：2006-11-23
申请号：US11432814
申请日：2006-05-11
IPC分类号： C12Q1/02
CPC分类号： G01N33/582 , C07D215/10 , C07D215/227 , C07D277/72 , C07D277/74 , C07D417/04 , C07D417/06 , C07D417/14 , C12Q1/6876 , G01N21/6428 , G01N21/6486 , G01N2021/6439 , G01N2201/06113 , Y10T436/143333
摘要： Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA.
摘要翻译： 公开了对RNA和单链DNA具有对双链DNA的高选择性的化合物。 化学化合物是在照射时变成荧光并与双链DNA相互作用的污渍，但在不存在双链DNA的情况下表现出减少的或没有荧光。 该化合物可用于各种生物学应用中，以定性或定量测定DNA，即使在RNA的存在下。
-
公开(公告)号：US20120028249A1
公开(公告)日：2012-02-02
申请号：US13126234
申请日：2009-10-20
申请人： Stephen Yue , Shih-Jung Huang , Jolene Bradford
发明人： Stephen Yue , Shih-Jung Huang , Jolene Bradford
IPC分类号： C12Q1/68 , C07H21/04 , C07D233/61 , C07D403/12 , C07D401/12 , C07D295/13 , C07C255/43 , C07D295/192 , C07D205/04 , C07D207/09
CPC分类号： G01N33/52 , C07C225/36 , C07C237/10 , C07C2603/24 , C07D205/04 , C07D213/36 , C07D233/61 , C07D249/04 , C07D295/13 , C07D295/192 , C07H21/04 , C09B1/5165 , C12Q1/6816 , C12Q1/6841 , G01N21/6428 , G01N2021/6441
摘要： Disclosed are near IR emitting fluorescent compounds; methods of making and kits containing the described compounds; and their use in fluorescence-based detection of biological materials.
摘要翻译： 近红外发射荧光化合物; 制备方法和含有所述化合物的试剂盒; 以及它们在荧光检测生物材料中的应用。
-
-
-
-
-
-
-
-
-
搜索结果
39 条记录 (耗时 0.039 秒)
