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公开(公告)号:US20100160633A1
公开(公告)日:2010-06-24
申请号:US12706837
申请日:2010-02-17
申请人: Jason W. Brown , Qing Dong , Bheema R. Paraselli , Jeffrey A. Stafford , Xianchang Gong , Yan Liu , Nicholas Scorah , Michael B. Wallace
发明人: Jason W. Brown , Qing Dong , Bheema R. Paraselli , Jeffrey A. Stafford , Xianchang Gong , Yan Liu , Nicholas Scorah , Michael B. Wallace
IPC分类号: C07F9/06
CPC分类号: C07F9/6561 , C07D471/04
摘要: Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
摘要翻译: 提供化合物用于与包含选自以下的化合物的激酶一起使用:其中变量如本文所定义。 还提供了包含这些化合物的药物组合物,试剂盒和制品; 用于制备化合物的方法和中间体; 以及使用所述化合物的方法。
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公开(公告)号:US20090156557A1
公开(公告)日:2009-06-18
申请号:US12103625
申请日:2008-04-15
申请人: Jason W. Brown , Qing Dong , Bheema R. Paraselli , Jeffrey A. Stafford , Xianchang Gong , Yan Liu , Nicholas Scorah , Michael B. Wallace
发明人: Jason W. Brown , Qing Dong , Bheema R. Paraselli , Jeffrey A. Stafford , Xianchang Gong , Yan Liu , Nicholas Scorah , Michael B. Wallace
IPC分类号: C07D487/04 , A61K31/437 , A61K31/496 , A61K31/5377 , A61K31/675 , C07F9/576 , C12N9/99 , A61P25/28 , A61P29/00 , A61P25/00 , A61P35/00
CPC分类号: C07F9/6561 , C07D471/04
摘要: Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
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公开(公告)号:US08278450B2
公开(公告)日:2012-10-02
申请号:US12103882
申请日:2008-04-16
申请人: Jason W. Brown , Qing Dong , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Michael B. Wallace , Hasanthi Wijesekera
发明人: Jason W. Brown , Qing Dong , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Michael B. Wallace , Hasanthi Wijesekera
IPC分类号: C07D471/00 , C07D209/88
CPC分类号: C07D471/14 , C07D241/18 , C07D401/12 , C07D471/04 , C07D487/04
摘要: Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
摘要翻译: 提供化合物用于与包含选自以下的化合物的激酶一起使用:其中变量如本文所定义。 还提供了包含这些化合物的药物组合物,试剂盒和制品; 用于制备化合物的方法和中间体; 以及使用所述化合物的方法。
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公开(公告)号:US20120095233A1
公开(公告)日:2012-04-19
申请号:US12103882
申请日:2008-04-16
申请人: Jason W. Brown , Qing Dong , Bheema R. Paraselli , Jeffrey A. Stafford , Michael B. Wallace , Hasanthi Wijesekera , Nicholas Scorah
发明人: Jason W. Brown , Qing Dong , Bheema R. Paraselli , Jeffrey A. Stafford , Michael B. Wallace , Hasanthi Wijesekera , Nicholas Scorah
IPC分类号: C07D471/04 , C07D209/88
CPC分类号: C07D471/14 , C07D241/18 , C07D401/12 , C07D471/04 , C07D487/04
摘要: Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
摘要翻译: 提供化合物用于与包含选自以下的化合物的激酶一起使用:其中变量如本文所定义。 还提供了包含这些化合物的药物组合物,试剂盒和制品; 用于制备化合物的方法和中间体; 以及使用所述化合物的方法。
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公开(公告)号:US20120252761A1
公开(公告)日:2012-10-04
申请号:US13437234
申请日:2012-04-02
申请人: Jason W. Brown , Qing Dong , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Michael B. Wallace , Hasanthi Wijesekera
发明人: Jason W. Brown , Qing Dong , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Michael B. Wallace , Hasanthi Wijesekera
IPC分类号: A61K31/675 , C07F9/6561
CPC分类号: C07D471/14 , C07D241/18 , C07D401/12 , C07D471/04 , C07D487/04
摘要: Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
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公开(公告)号:US08119655B2
公开(公告)日:2012-02-21
申请号:US11539857
申请日:2006-10-09
IPC分类号: A61K31/437 , C07D471/04
CPC分类号: C07D471/04 , C07D471/12 , C07D487/04 , C07D487/14
摘要: Compounds, pharmaceutical compositions, kits and methods are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
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公开(公告)号:US08288536B2
公开(公告)日:2012-10-16
申请号:US12755301
申请日:2010-04-06
申请人: Qing Dong , David J. Hosfield , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
发明人: Qing Dong , David J. Hosfield , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
IPC分类号: C07D487/04 , A61K31/517 , A61P19/02
CPC分类号: C07D487/04
摘要: Compounds, pharmaceutical compositions and kits are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
摘要翻译: 化合物,药物组合物和试剂盒提供用于包含选自以下的化合物的激酶:其中变量如本文所定义。
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公开(公告)号:US20100216765A1
公开(公告)日:2010-08-26
申请号:US12755301
申请日:2010-04-06
申请人: Qing Dong , David J. Hosfield , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
发明人: Qing Dong , David J. Hosfield , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
IPC分类号: A61K31/519 , C07D487/04 , A61K31/5377 , A61K31/53 , C07D471/04 , A61P35/00 , A61P25/00 , A61P37/02 , A61P25/28 , A61P3/10
CPC分类号: C07D487/04
摘要: Compounds, pharmaceutical compositions and kits are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
摘要翻译: 化合物,药物组合物和试剂盒提供用于包含选自以下的化合物的激酶:其中变量如本文所定义。
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公开(公告)号:US20100190816A1
公开(公告)日:2010-07-29
申请号:US12708304
申请日:2010-02-18
IPC分类号: A61K31/4745 , C07D491/02
CPC分类号: C07D471/04 , C07D471/12 , C07D487/04 , C07D487/14
摘要: Compounds, pharmaceutical compositions, kits and methods are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
摘要翻译: 提供化合物,药物组合物,试剂盒和方法用于包含选自以下的化合物的激酶:其中变量如本文所定义。
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公开(公告)号:US20090312288A1
公开(公告)日:2009-12-17
申请号:US12425249
申请日:2009-04-16
申请人: Jason W. Brown , Qing Dong , Anthony R. Gangloff , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Sanjib Das , Jonathon S. Salsbury
发明人: Jason W. Brown , Qing Dong , Anthony R. Gangloff , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Sanjib Das , Jonathon S. Salsbury
IPC分类号: A61K31/437 , C07D471/04 , C07D413/14 , C07D417/14 , A61K31/5377 , A61K31/541 , A61K31/675 , A61P25/28 , A61P35/00 , A61P19/02
CPC分类号: C07D471/04 , C07F9/6561
摘要: Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
摘要翻译: 提供化合物用于与包含选自以下的化合物的激酶一起使用:其中变量如本文所定义。 还提供了包含这些化合物的药物组合物,试剂盒和制品; 用于制备化合物的方法和中间体; 以及使用所述化合物的方法。
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