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1.发明申请Trimethylsilyl-Capped Polysiloxane Macromonomers Containing Polar Fluorinated Side-Chains 审中-公开含有极性氟化侧链的三甲基甲硅烷基封端的聚硅氧烷大分子单体公开(公告)号：US20090168013A1
公开(公告)日：2009-07-02
申请号：US12269442
申请日：2008-11-12
IPC分类号： G02C7/04 , C07F7/02 , C08F290/06
CPC分类号： C08F290/068 , C08G77/20 , C08G77/385 , G02B1/043 , C08L51/085
摘要： A method for reducing the modulus of polymer siloxane hydrogel compositions by employing monomeric polysiloxanes endcapped with trimethylsilyl to reduce the crosslinking density of the hydrogel. The synthesis consists of a single vessel acid catalyzed ring opening polymerization and may be employed to produce copolymers useful as hydrogel contact lens materials.
摘要翻译： 通过使用用三甲基甲硅烷基封端的单体聚硅氧烷降低聚合物硅氧烷水凝胶组合物的模量以降低水凝胶的交联密度的方法。 该合成由单容器酸催化的开环聚合组成，可用于产生可用作水凝胶隐形眼镜材料的共聚物。
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公开(公告)号：US06908978B2
公开(公告)日：2005-06-21
申请号：US10000136
申请日：2001-11-02
CPC分类号： C08G77/045 , A61L27/16 , C07F7/0838 , G02B1/043 , C08L51/085 , C08L51/08
摘要： Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more siloxysilane monomers or the copolymerization of one or more siloxysilane monomers with one or more aromatic or non-aromatic non-siloxy monomers, hydrophobic monomers or hydrophilic monomers.
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公开(公告)号：US06881809B2
公开(公告)日：2005-04-19
申请号：US10848308
申请日：2004-05-18
CPC分类号： C07F7/081 , Y10S623/905 , Y10S623/907
摘要： Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based silyl monomers or the copolymerization of one or more aromatic-based silyl monomers with one or more aromatic or non-aromatic non-siloxy-based monomers, hydrophobic monomers or hydrophilic monomers.
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公开(公告)号：US06762271B2
公开(公告)日：2004-07-13
申请号：US10003616
申请日：2001-11-02
IPC分类号： C08G7700
CPC分类号： C07F7/081 , Y10S623/905 , Y10S623/907
摘要： Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based silyl monomers or the copolymerization of one or more aromatic-based silyl monomers with one or more aromatic or non-aromatic non-siloxy-based monomers, hydrophobic monomers or hydrophilic monomers.
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5.发明授权High refractive-index, hydrophilic, arylsiloxy-containing monomers and polymers, and ophthalmic devices comprising such polymers 有权高折射率，亲水的，含芳基甲硅烷氧基的单体和聚合物，以及包含这种聚合物的眼科装置公开(公告)号：US07632904B2
公开(公告)日：2009-12-15
申请号：US11153470
申请日：2005-06-15
IPC分类号： C08F26/06 , C08F30/08 , C08F118/02
CPC分类号： C08G77/20 , A61L27/18 , C07F7/0838 , C08G77/16 , C08L83/04
摘要： Hydrophilic, arylsiloxy-containing monomers and macromonomers have at least a terminal hydrophilic group attached to an arylsiloxy group. The aryl groups attached to siloxy groups can be substituted with other hydrophilic groups. Polymers comprising such hydrophilic, arylsiloxy-containing monomers and macromonomers avoid or reduce the risk of forming vacuoles of absorbed water. Furthermore, such polymers have high refractive index, and, thus, are advantageously used for making ophthalmic devices, such as intraocular lenses, contact lenses, corneal rings, corneal inlays, and keratoprostheses.
摘要翻译： 亲水性，含芳基甲硅烷氧基的单体和大分子单体至少具有与芳基甲硅烷氧基连接的末端亲水基团。 连接到甲硅烷氧基的芳基可以被其它亲水基取代。 包含这种亲水性，含芳基甲硅烷氧基的单体和大分子单体的聚合物避免或降低形成吸收水的空泡的风险。 此外，这种聚合物具有高折射率，因此有利地用于制造眼科装置，例如眼内透镜，隐形眼镜，角膜环，角膜嵌体和角膜假体。
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6.发明授权High refractive-index siloxy-containing monomers and polymers, and ophthalmic devices comprising such polymers 有权含高折射率甲硅烷氧基的单体和聚合物，以及包含这种聚合物的眼科装置公开(公告)号：US07423108B2
公开(公告)日：2008-09-09
申请号：US11305606
申请日：2005-12-16
IPC分类号： C08G77/12
CPC分类号： C08G77/50 , G02B1/043 , C08L51/085 , C08L83/14
摘要： Siloxy-containing monomers, macromonomers, or polymers have at least a siloxy-containing side group that comprises a refractive-index increasing substituent. Polymeric compositions comprising such siloxy-containing monomers, macromonomers, or polymers are advantageously used for making ophthalmic devices, such as intraocular lenses, contact lenses, corneal rings, corneal inlays, and keratoprostheses.
摘要翻译： 含硅氧基的单体，大分子单体或聚合物具有至少含有甲硅烷氧基的侧基，其包含折射率增加取代基。 包含这种含甲硅烷氧基的单体，大分子单体或聚合物的聚合物组合物有利地用于制造眼科装置，例如眼内透镜，隐形眼镜，角膜环，角膜嵌体和角膜假体。
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公开(公告)号：US07132494B2
公开(公告)日：2006-11-07
申请号：US10848305
申请日：2004-05-18
IPC分类号： C08G77/00
CPC分类号： C07F7/081 , Y10S623/905 , Y10S623/907
摘要： Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based silyl monomers or the copolymerization of one or more aromatic-based silyl monomers with one or more aromatic or non-aromatic non-siloxy-based monomers, hydrophobic monomers or hydrophilic monomers.
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公开(公告)号：US06703378B1
公开(公告)日：2004-03-09
申请号：US10247452
申请日：2002-09-19
IPC分类号： A61K31695
CPC分类号： A61K31/695 , A61K9/0048 , A61K31/765
摘要： Fluorosilicone fluids useful as high-density fluid ocular tamponades and methods of producing, purifying and using the fluorosilicone fluids in an ocular surgical procedure for retinal treatment.
摘要翻译： 用作高密度流体眼压塞的氟硅酮流体，以及在用于视网膜处理的眼外科手术中制备，纯化和使用氟硅酮流体的方法。
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9.发明申请METHACRYLATE-BASED BULKY SIDE-CHAIN SILOXANE CROSS LINKERS FOR OPTICAL MEDICAL DEVICES 审中-公开用于光学医疗设备的基于甲基丙烯酸酯的双链双链交联剂公开(公告)号：US20120277342A1
公开(公告)日：2012-11-01
申请号：US13547170
申请日：2012-07-12
IPC分类号： C08F230/08 , C08L43/04
CPC分类号： C08G77/24 , C08F283/124 , C08F290/068 , C08G77/20 , G02B1/043 , Y10T428/21 , C08L51/085
摘要： Novel polymers for biomedical use, especially rigid gas permeable contact lenses that are based on bulky side-chain siloxane cross linkers. The siloxanes, either alone, or as copolymers with bulky and non-bulky mono-functional polymerizable siloxanes, fluoro monomers, such as hexafluoroisopropyl methacrylate, and hydrophilic monomers, result in transparent, high oxygen permeable polymers possessing excellent lathing and milling characteristics.
摘要翻译： 用于生物医学应用的新型聚合物，特别是基于体积大的侧链硅氧烷交联剂的刚性透气隐形眼镜。 单独的硅氧烷或作为与体积大和非膨松的单官能可聚合硅氧烷的共聚物，氟单体如甲基丙烯酸六氟异丙酯和亲水性单体，得到具有优异的车床和研磨特性的透明的高透氧性聚合物。
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10.发明申请METHACRYLATE-BASED BULKY SIDE-CHAIN SILOXANE CROSS LINKERS FOR OPTICAL MEDICAL DEVICES 失效用于光学医疗设备的基于甲基丙烯酸酯的双链双链交联剂公开(公告)号：US20100118261A1
公开(公告)日：2010-05-13
申请号：US12267633
申请日：2008-11-10
CPC分类号： C08G77/24 , C08F283/124 , C08F290/068 , C08G77/20 , G02B1/043 , Y10T428/21 , C08L51/085
摘要： Novel polymers for biomedical use, especially rigid gas permeable contact lenses that are based on bulky side-chain siloxane cross linkers. The siloxanes, either alone, or as copolymers with bulky and non-bulky mono-functional polymerizable siloxanes, fluoro monomers, such as hexafluoroisopropyl methacrylate, and hydrophilic monomers, result in transparent, high oxygen permeable polymers possessing excellent lathing and milling characteristics.
摘要翻译： 用于生物医学应用的新型聚合物，特别是基于体积大的侧链硅氧烷交联剂的刚性透气隐形眼镜。 单独的硅氧烷或作为与体积大和非膨松的单官能可聚合硅氧烷的共聚物，氟单体如甲基丙烯酸六氟异丙酯和亲水性单体，得到具有优异的车床和研磨特性的透明的高透氧性聚合物。
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