Method for preserving viral particles
    7.
    发明授权
    Method for preserving viral particles 失效
    保存病毒颗粒的方法

    公开(公告)号:US08313897B2

    公开(公告)日:2012-11-20

    申请号:US12531902

    申请日:2008-03-19

    申请人: Jeffrey Drew

    发明人: Jeffrey Drew

    IPC分类号: C12Q1/70 A61K39/02

    CPC分类号: C12N7/00 C12N2770/32151

    摘要: A method for preserving viral particles comprises: (i) providing an aqueous solution of one or more sugars, a polyethyleneimine and said viral particles wherein the concentration of polyethyleneimine is 15 μM or less based on the number-average molar mass (Mn) of the polyethyleneimine and the sugar concentration or, if more than one sugar is present, total sugar concentration is greater than 0.1 M; and (ii) drying the solution to form an amorphous solid matrix comprising said viral particles.

    摘要翻译: 一种用于保存病毒颗粒的方法包括:(i)提供一种或多种糖,聚乙烯亚胺和所述病毒颗粒的水溶液,其中聚乙烯亚胺的浓度基于摩尔质量(Mn)的平均摩尔质量(Mn)为15μM或更低 聚乙烯亚胺和糖浓度,或者如果存在多于一种糖,总糖浓度大于0.1M; 和(ii)干燥溶液以形成包含所述病毒颗粒的无定形固体基质。

    Method for Preserving Viral Particles
    9.
    发明申请
    Method for Preserving Viral Particles 失效
    保存病毒颗粒的方法

    公开(公告)号:US20100015177A1

    公开(公告)日:2010-01-21

    申请号:US12531902

    申请日:2008-03-19

    申请人: Jeffrey Drew

    发明人: Jeffrey Drew

    CPC分类号: C12N7/00 C12N2770/32151

    摘要: A method for preserving viral particles comprises: (i) providing an aqueous solution of one or more sugars, a polyethyleneimine and said viral particles wherein the concentration of polyethyleneimine is 15 μM or less based on the number-average molar mass (Mn) of the polyethyleneimine and the sugar concentration or, if more than one sugar is present, total sugar concentration is greater than 0.1 M; and (ii) drying the solution to form an amorphous solid matrix comprising said viral particles.

    摘要翻译: 一种用于保存病毒颗粒的方法包括:(i)提供一种或多种糖,聚乙烯亚胺和所述病毒颗粒的水溶液,其中聚乙烯亚胺的浓度为15μm或更小,基于摩尔质量 聚乙烯亚胺和糖浓度,或者如果存在多于一种糖,总糖浓度大于0.1M; 和(ii)干燥溶液以形成包含所述病毒颗粒的无定形固体基质。