公开(公告)号：US20110282368A1

公开(公告)日：2011-11-17

申请号：US12778587

申请日：2010-05-12

申请人： Jeffrey S. Swayze ,  Foster B. Stulen ,  Mark H. Ransick ,  Steven G. Hall ,  John A. Hibner ,  Julia J. Hwang ,  Yolanda F. Carter ,  Frederick E. Shelton, IV

发明人： Jeffrey S. Swayze ,  Foster B. Stulen ,  Mark H. Ransick ,  Steven G. Hall ,  John A. Hibner ,  Julia J. Hwang ,  Yolanda F. Carter ,  Frederick E. Shelton, IV

IPC分类号： A61B17/22 ,  A61B17/00

CPC分类号： A61B17/0057 ,  A61B10/0283 ,  A61B17/00491 ,  A61B17/32002 ,  A61B17/320758 ,  A61B18/1492 ,  A61B2017/00623 ,  A61B2017/00641 ,  A61B2017/00654 ,  A61B2017/00867 ,  A61B2017/00893 ,  A61B2017/00969 ,  A61B2017/22067 ,  A61B2017/320064 ,  A61B2217/005 ,  A61B2217/007 ,  A61M1/0084

摘要： A fistula repair system includes a debriding member that may be inserted into a fistula to debride the fistula wall. The debriding member may include a plurality of selectively extendable barbs. The barbs may be hollow to deliver a medical fluid within the fistula. The debriding member may also include a plurality of openings configured to communicate the medical fluid within the fistula. The barbs may extend through the openings. The openings may include associated protrusions that are configured to debride the fistula wall. The medical fluid may include a slurry of tissue and a scaffold material. The tissue in the slurry may comprise minced tissue that was harvested from the patient afflicted with the fistula. A balloon may be used to at least temporarily seal one end of the fistula. An RF probe or mechanical hook member may be used to seal the other end of the fistula.

摘要翻译： 瘘修复系统包括可以插入瘘管以清除瘘管壁的清创构件。 清创构件可以包括多个可选择性地可延伸的倒钩。 倒钩可以是中空的，以在瘘管内输送医用流体。 解围构件还可以包括多个开口，其被构造成在瘘管内传送医用流体。 倒钩可以延伸穿过开口。 开口可以包括被配置为清除瘘管壁的相关联的突起。 医用流体可以包括组织和支架材料的浆液。 浆液中的组织可以包括从患有瘘​​管的患者收获的切碎的组织。 可以使用气囊来至少临时密封瘘的一端。 可以使用RF探针或机械钩构件来密封瘘的另一端。

公开(公告)号：US08714360B2

公开(公告)日：2014-05-06

申请号：US12778806

申请日：2010-05-12

申请人： Jeffrey S. Swayze ,  Mark H. Ransick ,  Foster B. Stulen

发明人： Jeffrey S. Swayze ,  Mark H. Ransick ,  Foster B. Stulen

IPC分类号： C02F1/36

CPC分类号： C12M47/04 ,  B01D21/283 ,  B33Y80/00 ,  C12M47/02

摘要： A device is operable to separate tissue particles. The device comprises a reservoir and an ultrasonic transducer. The reservoir is configured to receive tissue particles in a fluid. The ultrasonic transducer is operable to emit ultrasonic energy toward tissue particles in the reservoir. Control circuitry is configured to drive the ultrasonic transducer at parameters selected to provide movement of tissue particles in the first reservoir based on the size of the tissue particles. The ultrasonic transducer may thus drive the tissue particles toward respective outlets or at particular times based on their particle size. An electrically driven screen may be used to separate tissue particles from liquid. An ultrasonic mincing device may be used to mince tissue particles whose size exceeds a predetermined size range.

摘要翻译： 装置可操作以分离组织颗粒。 该装置包括储存器和超声换能器。 储存器构造成接收流体中的组织颗粒。 超声波换能器可操作地朝储存器中的组织颗粒发射超声波能量。 控制电路被配置为在选择的参数下驱动超声波换能器，以根据组织颗粒的尺寸提供组织颗粒在第一储存器中的移动。 因此，超声换能器可以基于它们的粒度将组织颗粒驱动到相应的出口或特定时间。 可以使用电驱动屏幕来将组织颗粒与液体分离。 可以使用超声波切碎装置来破碎其尺寸超过预定尺寸范围的组织颗粒。

公开(公告)号：US20110282241A1

公开(公告)日：2011-11-17

申请号：US12777472

申请日：2010-05-11

申请人： Jeffrey S. Swayze ,  Foster B. Stulen ,  Mark H. Ransick

发明人： Jeffrey S. Swayze ,  Foster B. Stulen ,  Mark H. Ransick

IPC分类号： A61B10/02

CPC分类号： A61B10/0275 ,  A61B10/0283

摘要： A tissue harvesting and processing apparatus comprises a body and a distally extending needle. The needle includes an aperture configured to receive tissue. A tissue cutting member is movable relative to the needle to sever a specimen from tissue protruding through the aperture. The tissue cutting member is further operable to mince the severed tissue specimen. The minced tissue may be mixed with a medical fluid component contained in a reservoir. A plunger may expel the medical fluid mixture from the needle. An applier tip may be coupled with the needle to facilitate administration of the medical fluid mixture at a target site in a patient. The needle may comprise a cannula with a needle adapter, which be removed from the cannula to allow the applier tip to be coupled with the cannula. The tissue cutting member may comprise a perforated disc or tube with inwardly projecting blades.

摘要翻译： 组织采集和处理装置包括主体和远端延伸的针。 针包括构造成接收组织的孔。 组织切割构件可相对于针移动，以从通过孔突出的组织切断样本。 组织切割构件还可操作以切割切断的组织标本。 切碎的组织可以与容纳在容器中的医用液体组分混合。 柱塞可以从针排出医用流体混合物。 施加器尖端可以与针联接以便于在患者的目标部位处施用医用流体混合物。 针可以包括具有针适配器的套管，其从套管移除以允许施放器尖端与套管联接。 组织切割构件可以包括具有向内突出的叶片的穿孔盘或管。

公开(公告)号：US08568446B2

公开(公告)日：2013-10-29

申请号：US12779400

申请日：2010-05-13

申请人： Takashi Kurokawa ,  Christopher W. Widenhouse ,  Agnieszka Seyda ,  Jeffrey S. Swayze ,  Foster B. Stulen ,  Mark H. Ransick ,  Richard W. Timm ,  Shailendra K. Parihar ,  Shelby L. Cook Kornbluth

发明人： Takashi Kurokawa ,  Christopher W. Widenhouse ,  Agnieszka Seyda ,  Jeffrey S. Swayze ,  Foster B. Stulen ,  Mark H. Ransick ,  Richard W. Timm ,  Shailendra K. Parihar ,  Shelby L. Cook Kornbluth

IPC分类号： A61M37/00

CPC分类号： A61B17/0057 ,  A61B10/0275 ,  A61B10/0283 ,  A61B17/00491 ,  A61B17/07207 ,  A61B17/12099 ,  A61B17/12186 ,  A61B2017/00495 ,  A61B2017/00641 ,  A61B2017/22067 ,  A61F5/0083 ,  A61M5/19 ,  A61M5/204 ,  A61M5/2448 ,  A61M5/31586 ,  A61M25/10 ,  A61M2005/2414

摘要： A surgical device comprises a housing, a plurality of media reservoirs, an end effector, and a pumping device. Each media reservoir is configured to receive at least one component of a tissue repair composition. The end effector is configured for insertion into a lumen to deliver a tissue repair composition into that lumen. The end effector has at least one fluid conduit and at least one orifice in communication with the fluid conduit. The pumping device is operable to urge a tissue repair composition comprising at least a portion of the contents of the plurality of media reservoirs through the fluid conduit of the end effector such that the tissue repair composition is expelled from the at least one orifice. The media reservoirs may contain medical fluid components such as viable cells and scaffold material to repair a fistula or address some other condition in a patient.

摘要翻译： 手术装置包括壳体，多个介质容器，末端执行器和泵送装置。 每个介质储存器构造成接收组织修复组合物的至少一个组分。 末端执行器构造成用于插入内腔以将组织修复组合物递送到该内腔中。 末端执行器具有至少一个流体导管和与流体导管连通的至少一个孔口。 抽吸装置可操作以通过端部执行器的流体管道促使包含多个介质容器的内容物的至少一部分的组织修复组合物，使得组织修复组合物从至少一个孔排出。 介质储存器可以包含医疗流体组分，例如活细胞和支架材料，以修复瘘管或解决患者中的一些其他状况。

公开(公告)号：US20110282324A1

公开(公告)日：2011-11-17

申请号：US12779400

申请日：2010-05-13

申请人： Takashi Kurokawa ,  Christopher W. Widenhouse ,  Agnieszka Seyda ,  Jeffrey S. Swayze ,  Foster B. Stulen ,  Mark H. Ransick ,  Richard W. Timm ,  Shailendra K. Parihar ,  Shelby L. Cook Kornbluth

发明人： Takashi Kurokawa ,  Christopher W. Widenhouse ,  Agnieszka Seyda ,  Jeffrey S. Swayze ,  Foster B. Stulen ,  Mark H. Ransick ,  Richard W. Timm ,  Shailendra K. Parihar ,  Shelby L. Cook Kornbluth

IPC分类号： A61M37/00 ,  A61M1/00

CPC分类号： A61B17/0057 ,  A61B10/0275 ,  A61B10/0283 ,  A61B17/00491 ,  A61B17/07207 ,  A61B17/12099 ,  A61B17/12186 ,  A61B2017/00495 ,  A61B2017/00641 ,  A61B2017/22067 ,  A61F5/0083 ,  A61M5/19 ,  A61M5/204 ,  A61M5/2448 ,  A61M5/31586 ,  A61M25/10 ,  A61M2005/2414

摘要： A surgical device comprises a housing, a plurality of media reservoirs, an end effector, and a pumping device. Each media reservoir is configured to receive at least one component of a tissue repair composition. The end effector is configured for insertion into a lumen to deliver a tissue repair composition into that lumen. The end effector has at least one fluid conduit and at least one orifice in communication with the fluid conduit. The pumping device is operable to urge a tissue repair composition comprising at least a portion of the contents of the plurality of media reservoirs through the fluid conduit of the end effector such that the tissue repair composition is expelled from the at least one orifice. The media reservoirs may contain medical fluid components such as viable cells and scaffold material to repair a fistula or address some other condition in a patient.

摘要翻译： 手术装置包括壳体，多个介质容器，末端执行器和泵送装置。 每个介质储存器构造成接收组织修复组合物的至少一个组分。 末端执行器构造成用于插入内腔以将组织修复组合物递送到该内腔中。 末端执行器具有至少一个流体导管和与流体导管连通的至少一个孔口。 抽吸装置可操作以通过端部执行器的流体管道促使包含多个介质容器的内容物的至少一部分的组织修复组合物，使得组织修复组合物从至少一个孔排出。 介质储存器可以包含医疗流体组分，例如活细胞和支架材料，以修复瘘管或解决患者中的一些其他状况。

公开(公告)号：US20110281319A1

公开(公告)日：2011-11-17

申请号：US12778806

申请日：2010-05-12

申请人： Jeffrey S. Swayze ,  Mark H. Ransick ,  Foster B. Stulen

发明人： Jeffrey S. Swayze ,  Mark H. Ransick ,  Foster B. Stulen

IPC分类号： C12N13/00 ,  C12M1/00

CPC分类号： C12M47/04 ,  B01D21/283 ,  B33Y80/00 ,  C12M47/02

摘要： A device is operable to separate tissue particles. The device comprises a reservoir and an ultrasonic transducer. The reservoir is configured to receive tissue particles in a fluid. The ultrasonic transducer is operable to emit ultrasonic energy toward tissue particles in the reservoir. Control circuitry is configured to drive the ultrasonic transducer at parameters selected to provide movement of tissue particles in the first reservoir based on the size of the tissue particles. The ultrasonic transducer may thus drive the tissue particles toward respective outlets or at particular times based on their particle size. An electrically driven screen may be used to separate tissue particles from liquid. An ultrasonic mincing device may be used to mince tissue particles whose size exceeds a predetermined size range.

摘要翻译： 装置可操作以分离组织颗粒。 该装置包括储存器和超声换能器。 储存器构造成接收流体中的组织颗粒。 超声波换能器可操作地朝储存器中的组织颗粒发射超声波能量。 控制电路被配置为在选择的参数下驱动超声波换能器，以根据组织颗粒的尺寸提供组织颗粒在第一储存器中的移动。 因此，超声换能器可以基于它们的粒度将组织颗粒驱动到相应的出口或特定时间。 可以使用电驱动屏幕来将组织颗粒与液体分离。 可以使用超声波切碎装置来破碎其尺寸超过预定尺寸范围的组织颗粒。

公开(公告)号：US10123798B2

公开(公告)日：2018-11-13

申请号：US13433141

申请日：2012-03-28

申请人： Chester O. Baxter, III ,  Frederick E. Shelton, IV ,  Charles J. Scheib ,  Christopher W. Widenhouse ,  William B. Weisenburgh, II ,  John L. Stammen ,  Mark H. Ransick ,  Stephanie A. Mutchler ,  Gary W. Knight ,  Michael S. Cropper ,  Sean P. Conlon ,  Jeffrey S. Swayze

发明人： Chester O. Baxter, III ,  Frederick E. Shelton, IV ,  Charles J. Scheib ,  Christopher W. Widenhouse ,  William B. Weisenburgh, II ,  John L. Stammen ,  Mark H. Ransick ,  Stephanie A. Mutchler ,  Gary W. Knight ,  Michael S. Cropper ,  Sean P. Conlon ,  Jeffrey S. Swayze

IPC分类号： A61B17/072 ,  A61B17/00 ,  A61B17/064 ,  A61B17/115 ,  A61B17/29 ,  A61B17/32

摘要： A tissue thickness compensator may generally comprise a first layer comprising a first biocompatible material sealingly enclosed in a water impermeable material and a second layer comprising a second biocompatible material comprising at least one encapsulation, wherein the first biocompatible material expands when contacted with a fluid. The tissue thickness compensator may comprise a haemostatic agent, an anti-inflammatory agent, an antibiotic agent, anti-microbial agent, an anti-adhesion agent, an anti-coagulant agent, a medicament, and/or pharmaceutically active agent. The encapsulation may comprise a biodegradable material to degrade in vivo and/or in situ. The tissue thickness compensator may comprise a hydrogel. The reaction product may comprise a fluid-swellable composition. Articles of manufacture comprising the tissue thickness compensator and methods of making and using the tissue thickness compensator are also described.

公开(公告)号：US20110132964A1

公开(公告)日：2011-06-09

申请号：US13027641

申请日：2011-02-15

申请人： William B. Weisenburgh, II ,  Jerome R. Morgan ,  Kyle P. Moore ,  Mark H. Ransick ,  Steven G. Hall ,  Randall J. Tanguay ,  Jeffrey D. Messerly ,  Galen C. Robertson ,  Andrew M. Zwolinski ,  Jeffrey S. Swayze ,  Thomas W. Huitema ,  Glen A. Armstrong ,  Shailendra K. Parihar ,  Donna L. Korvick ,  Richard W. Timm ,  Kevin R. Doll ,  Bret W. Smith ,  William D. Kelly ,  Ronald J. Kolata ,  Joshua R. Uth ,  Charles J. Scheib ,  Geoffrey C. Hueil ,  Mark S. Ortiz ,  Douglas B. Hoffman ,  Patrick A. Weizman ,  Dean B. Bruewer ,  Gregory B. Blair ,  Frederick E. Shelton, IV

发明人： William B. Weisenburgh, II ,  Jerome R. Morgan ,  Kyle P. Moore ,  Mark H. Ransick ,  Steven G. Hall ,  Randall J. Tanguay ,  Jeffrey D. Messerly ,  Galen C. Robertson ,  Andrew M. Zwolinski ,  Jeffrey S. Swayze ,  Thomas W. Huitema ,  Glen A. Armstrong ,  Shailendra K. Parihar ,  Donna L. Korvick ,  Richard W. Timm ,  Kevin R. Doll ,  Bret W. Smith ,  William D. Kelly ,  Ronald J. Kolata ,  Joshua R. Uth ,  Charles J. Scheib ,  Geoffrey C. Hueil ,  Mark S. Ortiz ,  Douglas B. Hoffman ,  Patrick A. Weizman ,  Dean B. Bruewer ,  Gregory B. Blair ,  Frederick E. Shelton, IV

IPC分类号： A61B17/068

CPC分类号： A61B17/105 ,  A61B17/068 ,  A61B17/07207 ,  A61B17/3205 ,  A61B17/3209 ,  A61B2017/00473 ,  A61B2017/07214 ,  A61B2017/2931

摘要： In various embodiments, a surgical stapling instrument can include a handle, a shaft extending from the handle, wherein the shaft defines an axis, and a disposable loading unit which is assembled to the shaft in a direction which is transverse to the shaft axis. Such a connection between the disposable loading unit and the shaft can prevent, or at least inhibit, the disposable loading unit from being unintentionally displaced proximally and/or distally relative to the shaft of the surgical instrument. The surgical stapling instrument and/or disposable loading unit can further include a threaded collar and/or detent assembly configured to hold the disposable loading unit in place. In various embodiments, a disposable loading unit can include a lockout feature which can prevent, or at least inhibit, an expended disposable loading unit from being reassembled to the elongated body of the surgical instrument.

摘要翻译： 在各种实施例中，外科缝合器械可以包括手柄，从手柄延伸的轴，其中轴限定轴线，以及一个一次性加载单元，其在横向于轴线的方向上组装到轴上。 一次性加载单元和轴之间的这种连接可以防止或至少阻止一次性加载单元相对于外科器械的轴向近侧和/或远端被无意地移位。 外科缝合器械和/或一次性装载单元还可包括构造成将一次性装载单元保持在适当位置的螺纹环和/或制动组件。 在各种实施例中，一次性加载单元可以包括锁定特征，其可以防止或至少抑制消耗的一次性装载单元被重新组装到外科器械的细长主体。

公开(公告)号：US20090206140A1

公开(公告)日：2009-08-20

申请号：US12031873

申请日：2008-02-15

申请人： Charles J. Scheib ,  Geoffrey C. Hueil ,  Mark S. Ortiz ,  Douglas B. Hoffman ,  Patrick A. Weizman ,  Dean B. Bruewer ,  Kevin R. Doll ,  Bret W. Smith ,  William D. Kelly ,  Ronald J. Kolata ,  Joshua R. Uth ,  Frederick E. Shelton, IV ,  William B. Weisenburgh, II ,  Jerome R. Morgan ,  Kyle P. Moore ,  Mark H. Ransick ,  Steven G. Hall ,  Randall J. Tanguay ,  Jeffrey D. Messerly ,  Galen C. Robertson ,  Andrew M. Zwolinski ,  Jeffrey S. Swayze ,  Thomas W. Huitema ,  Glen A. Armstrong ,  Shailendra K. Parihar ,  Donna L. Korvick ,  Richard W. Timm ,  Gregory B. Blair

发明人： Charles J. Scheib ,  Geoffrey C. Hueil ,  Mark S. Ortiz ,  Douglas B. Hoffman ,  Patrick A. Weizman ,  Dean B. Bruewer ,  Kevin R. Doll ,  Bret W. Smith ,  William D. Kelly ,  Ronald J. Kolata ,  Joshua R. Uth ,  Frederick E. Shelton, IV ,  William B. Weisenburgh, II ,  Jerome R. Morgan ,  Kyle P. Moore ,  Mark H. Ransick ,  Steven G. Hall ,  Randall J. Tanguay ,  Jeffrey D. Messerly ,  Galen C. Robertson ,  Andrew M. Zwolinski ,  Jeffrey S. Swayze ,  Thomas W. Huitema ,  Glen A. Armstrong ,  Shailendra K. Parihar ,  Donna L. Korvick ,  Richard W. Timm ,  Gregory B. Blair

IPC分类号： A61B17/068 ,  A61B17/064

CPC分类号： A61B17/07207 ,  A61B2017/00473 ,  A61B2017/07214 ,  A61B2017/320052

摘要： In various embodiments, an anvil of a disposable loading unit including a first member having staple pockets for deforming staples, a first cover plate secured to the first member, and a second cover plate secured to at least one of the first member and the first cover plate, wherein the first and second cover plates can be configured to support the first member. In at least one embodiment, an anvil can include a first member inserted into a second member, where at least one of the first and second members can be deformed to retain one to the other. In various embodiments, a surgical stapling instrument can include a disposable loading unit comprising a staple cartridge, an anvil, and a sleeve, wherein the sleeve can be configured to be slid relative to the staple cartridge and the anvil to hold the anvil in a closed position.

摘要翻译： 在各种实施例中，一次性加载单元的砧座包括具有用于使订书钉变形的订书钉仓的第一构件，固定到第一构件的第一盖板和固定到第一构件和第一盖板中的至少一个的第二盖板 板，其中第一和第二盖板可被配置为支撑第一构件。 在至少一个实施例中，砧可以包括插入第二构件中的第一构件，其中第一构件和第二构件中的至少一个可以变形以保持彼此。 在各种实施例中，外科缝合器械可以包括一次性加载单元，其包括钉仓，砧座和套筒，其中所述套筒可以被构造成相对于钉仓和砧座滑动以将砧座保持在闭合状态 位置。

公开(公告)号：US20090206134A1

公开(公告)日：2009-08-20

申请号：US12031539

申请日：2008-02-14

申请人： Jeffrey S. Swayze ,  Thomas W. Huitema ,  Glen A. Armstrong ,  Shailendra K. Parihar ,  Donna L. Korvick ,  Richard W. Timm ,  Kevin R. Doll ,  Bret W. Smith ,  William D. Kelly ,  Ronald J. Kolata ,  Joshua R. Uth ,  Charles J. Scheib ,  Frederick E. Shelton, IV ,  William B. Weisenburgh, II ,  Jerome R. Morgan ,  Kyle P. Moore ,  Mark H. Ransick

发明人： Jeffrey S. Swayze ,  Thomas W. Huitema ,  Glen A. Armstrong ,  Shailendra K. Parihar ,  Donna L. Korvick ,  Richard W. Timm ,  Kevin R. Doll ,  Bret W. Smith ,  William D. Kelly ,  Ronald J. Kolata ,  Joshua R. Uth ,  Charles J. Scheib ,  Frederick E. Shelton, IV ,  William B. Weisenburgh, II ,  Jerome R. Morgan ,  Kyle P. Moore ,  Mark H. Ransick

IPC分类号： A61B17/03

CPC分类号： A61B17/07207 ,  A61B2017/07214 ,  A61B2017/07285

摘要： A disposable loading unit for operable attachment to a surgical stapling apparatus. The disposable loading unit may have a carrier that supports a staple cartridge and an anvil assembly that is movable coupled to the carrier. The various embodiments may further have an axial drive assembly that is configured to impart a closing motion to the anvil assembly and also supports a cutting blade thereon. The axial drive assembly is configured to receive firing motions and retraction motions from the surgical stapling apparatus. Various embodiments have an anvil release assembly that enables the anvil assembly to be released from a clamping orientation in the event that the cutting blade becomes jammed during operation.

摘要翻译： 一种用于可操作地附接到外科缝合装置的一次性装载单元。 一次性装载单元可以具有支撑钉仓的托架和可移动地联接到托架的砧座组件。 各种实施例还可以具有轴向驱动组件，该轴向驱动组件被配置为向砧座组件施加闭合运动，并且还在其上支撑切割刀片。 轴向驱动组件构造成接收来自外科缝合装置的发射运动和缩回运动。 各种实施例具有砧座释放组件，其在切割刀片在操作期间卡住的情况下使得砧座组件能够从夹紧方向释放。