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公开(公告)号：US5957889A
公开(公告)日：1999-09-28
申请号：US615298
申请日：1996-08-29
申请人： Jens Ulrik Poulsen , Henrik Ljunggreen , Henning Munk Ejlersen , Jens Munk , Lars Peter Klitmose , Preben Broskov Nielsen , S.o slashed.ren Mikkelsen , Jens M.o slashed.ller-Jensen , Anders Heger
发明人： Jens Ulrik Poulsen , Henrik Ljunggreen , Henning Munk Ejlersen , Jens Munk , Lars Peter Klitmose , Preben Broskov Nielsen , S.o slashed.ren Mikkelsen , Jens M.o slashed.ller-Jensen , Anders Heger
CPC分类号： A61M5/14566 , B05C17/0113
摘要： In a displacement system for controlled infusion of a liquid from a cartridge comprising a tubular vessel (1), which is at a rear end closed by a piston (3) which may be forced by a piston rod (8) moving into the vessel (1) in the axial direction thereof to press out the liquid through an outlet (2) arranged at a front end of the vessel (1), the piston rod (8) is provided as a flexible incompressible construction which is by a piston rod guide (9) behind the rear end of the cartridge deflected away from the axis of this cartridge, preferably 180.degree.. The piston rod guide (9) has a guiding track comprising a curved part and linear parts at each end of the curved part ensuring that the piston rod is guided along a length (a) in the direction of the axis of the cartridge which length (a) is longer than the distance (b) between the two axes of the piston rod parts projecting from the piston rod guide. The guiding track is further elaborated to the very shape which the curved part of the piston rod will spontaneously adopt when its end portions are kept parallel.
摘要翻译： PCT No.PCT / DK94 / 00361 Sec。 371日期：1996年8月29日 102（e）日期1996年8月29日PCT 1994年9月27日PCT公布。 公开号WO95 / 09021 日期1995年4月6日在用于从包括管状容器（1）的药筒受控输注液体的位移系统中，所述管状容器（1）的后端被可由活塞杆（8）迫使的活塞（3）封闭， 沿着其轴向移动到容器（1）中以通过布置在容器（1）的前端的出口（2）将液体挤压出来，活塞杆（8）被设置为柔性不可压缩结构，其是 通过活塞杆引导件（9）在盒的后端后面偏离该盒的轴线，优选地为180度。 活塞杆引导件（9）具有引导轨道，该引导轨道包括弯曲部分和在弯曲部分的每个端部处的直线部分，确保活塞杆沿长度方向（a）沿长度方向（a）被引导， a）比从活塞杆引导件突出的活塞杆部件的两个轴线之间的距离（b）长。 引导轨进一步细化为当其端部保持平行时活塞杆的弯曲部分将自动采用的形状。
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公开(公告)号：US20110046454A1
公开(公告)日：2011-02-24
申请号：US12673849
申请日：2008-08-14
CPC分类号： A61M37/0069 , A61B5/14503 , A61B5/14532 , A61B5/6848 , A61B17/205 , A61M5/3286 , A61M5/3287 , A61M5/425 , A61M5/427 , A61M5/46 , A61M2005/1581 , A61M2005/1583 , A61M2005/1585 , A61M2205/195
摘要： An injection apparatus (1) for making an injection at a predetermined depth in skin comprises: a first skin positioning member (4, 26); a second skin positioning member (3, 54), wherein the first and second skin positioning members lie or are moveable to lie in an injection arrangement; an injection needle (50); and means guiding the injection needle for movement from a parking position above the skin, through the lower surface of the second skin positioning member to slide beneath the first skin positioning member to an injection position. A further injection apparatus comprises: an injection needle; a plunger (44) within the injection needle; and means for retracting the injection needle such that material to be injected is expelled from the injection needle by the plunger.
摘要翻译： 一种用于在皮肤中以预定深度进行注射的注射装置（1）包括：第一皮肤定位部件（4,26）; 第二皮肤定位构件（3,44），其中所述第一和第二皮肤定位构件位于或可移动地位于注射装置中; 注射针（50）; 并且引导所述注射针从所述皮肤上方的停车位置移动通过所述第二皮肤定位部件的下表面，以在所述第一皮肤定位部件的下方滑动到注射位置。 另外的注射装置包括：注射针; 注射针内的柱塞（44）; 以及用于缩回注射针的装置，使得待注射的材料被柱塞从注射针排出。
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公开(公告)号：US06994691B2
公开(公告)日：2006-02-07
申请号：US10370104
申请日：2003-02-21
IPC分类号： A61M5/00
CPC分类号： A61M5/46 , A61M5/3287 , A61M5/427 , A61M2005/31598
摘要： An injection apparatus is described for making an injection at a predetermined depth in skin, including: a skin positioning member for positioning on a patch of skin within an area of skin such that at least a part of the patch of skin may be held elevated above or depressed below the area of skin, an injection needle, and a guidance mechanism for guiding the injection needle to slide beneath the skin positioning member to an injection position in which the distal end of the needle lies at a predetermined distance below the skin positioning member. An injection apparatus is also described including a detachable marker unit and a securing element for securing the marker unit at an injection site prior to the making of an injection to mark the position of the injection site.
摘要翻译： 描述了一种用于在皮肤中以预定深度进行注射的注射装置，包括：皮肤定位构件，用于定位在皮肤区域内的皮肤贴片上，使得皮肤斑块的至少一部分可以保持在上面 或凹陷在皮肤区域以下，注射针和引导机构，用于引导注射针在皮肤定位构件下方滑动到注射位置，其中针的远端位于皮肤定位构件下方的预定距离处 。 还描述了一种注射装置，其包括可拆卸标记单元和固定元件，用于在进行注射之前将标记单元固定在注射部位以标记注射部位的位置。
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公开(公告)号：US08409140B2
公开(公告)日：2013-04-02
申请号：US12673849
申请日：2008-08-14
IPC分类号： A61M5/00
CPC分类号： A61M37/0069 , A61B5/14503 , A61B5/14532 , A61B5/6848 , A61B17/205 , A61M5/3286 , A61M5/3287 , A61M5/425 , A61M5/427 , A61M5/46 , A61M2005/1581 , A61M2005/1583 , A61M2005/1585 , A61M2205/195
摘要： An injection apparatus for making an injection at a predetermined depth in skin comprises: a first skin positioning member, a second skin positioning member, wherein the first and second skin positioning members lie or are moveable to lie in an injection arrangement; an injection needle; and an injection needle movement guide to guide the injection needle for movement from a parking position above the skin, through the lower surface of the second skin positioning member to slide beneath the first skin positioning member to an injection position. A further injection apparatus comprises: an injection needle; a plunger within the injection needle; and a retractor to retract the injection needle such that material to be injected is expelled from the injection needle by the plunger.
摘要翻译： 用于在皮肤中以预定深度进行注射的注射装置包括：第一皮肤定位构件，第二皮肤定位构件，其中第一和第二皮肤定位构件位于或可移动地位于注射装置中; 注射针 以及注射针移动引导件，用于引导注射针从皮肤上方的停车位置移动，穿过第二皮肤定位构件的下表面，以在第一皮肤定位构件下方滑动到注射位置。 另外的注射装置包括：注射针; 注射针内的柱塞; 以及收缩器，用于缩回注射针，使得待注射的材料被柱塞从注射针排出。
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公开(公告)号：US06544238B1
公开(公告)日：2003-04-08
申请号：US09043950
申请日：1998-03-27
IPC分类号： A61M500
摘要： A needle assembly comprises an injection needle and a needle hub, mountable on a syringe, for securing the injection needle. The needle has an injection part extending axially from the hub and terminating in a skin piercing obliquely cut end. The length of the injection part is between 4 and 6 mm, thereby facilitating a proper subcutaneous injection. Also, preferably either (a) the outer diameter of the needle is smaller than 0.320 mm and the bore diameter is larger than 0.165 mm, or (b) the outer diameter is smaller than 0.298 mm and the bore diameter is larger than 0.133 mm. Also, preferably the hub includes an axially extending protrusion, from which the injection part extends, to facilitate insertion of the injection part into the skin of a user at an oblique angle.
摘要翻译： 针组件包括注射针和针座，可安装在注射器上，用于固定注射针。 针具有从轮毂轴向延伸并终止于皮肤穿透的倾斜切割端的注射部分。 注射部分的长度在4和6mm之间，从而便于适当的皮下注射。 此外，优选（a）针的外径小于0.320mm，孔直径大于0.165mm，或（b）外径小于0.298mm，孔直径大于0.133mm。 此外，优选地，毂包括轴向延伸的突起，注射部分从该突出部延伸，以便于将注射部分以倾斜角插入使用者的皮肤中。
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公开(公告)号：US20130060106A1
公开(公告)日：2013-03-07
申请号：US13478478
申请日：2012-05-23
IPC分类号： A61B5/1459 , G01N30/00 , A61B5/1455
CPC分类号： A61B5/14532 , A61B5/0002 , A61B5/0004 , A61B5/14556 , A61B5/1459 , A61B5/1473 , A61B5/4839 , A61B5/6848 , A61B5/6849 , A61B5/742 , A61M5/1723 , A61M2230/201 , G01N21/6408 , G01N21/6428 , G01N21/7703 , G01N33/66 , G01N2021/6441 , G01N2021/6484 , G01N2021/772 , G01N2021/7733 , G01N2021/775 , G01N2021/7759 , G01N2021/7786 , G01N2333/4724
摘要： An optical glucose sensor may include an optical fiber and a glucose-permeable membrane having a hollow interior and being coupled to the optical fiber's distal end. The membrane's hollow interior provides a compartment to house a competitive glucose binding affinity assay. The assay may include a glucose analog that may be labeled with a dye, and a glucose receptor that may be labeled with a fluorophore. The optical fiber may include a compound parabolic concentrator tip, and the compartment may additionally house a reflector disposed so as to face the optical fiber's tip. A fluorophore-labeled assay may be interrogated by an optical interrogating system including a light source and a filter substrate having one or more coatings to effect, e.g., an excitation filter and/or an emission filter. The interrogating system may be manufactured as a stacked planar integrated optical system and diced into smaller units.
摘要翻译： 光学葡萄糖传感器可以包括具有中空内部并耦合到光纤远端的光纤和葡萄糖透过膜。 膜的中空内部提供了一个容纳竞争性葡萄糖结合亲和力测定的隔室。 该测定可以包括可用染料标记的葡萄糖类似物和可用荧光团标记的葡萄糖受体。 光纤可以包括复合抛物面聚光器尖端，并且隔室可另外容纳设置成面对光纤尖端的反射器。 荧光团标记的测定可以由包括光源和具有一个或多个涂层的过滤器衬底的光学询问系统询问，以实现例如激发过滤器和/或发射过滤器。 询问系统可以被制造为堆叠的平面集成光学系统并且被切成更小的单元。
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公开(公告)号：US5968021A
公开(公告)日：1999-10-19
申请号：US696898
申请日：1996-08-22
CPC分类号： A61M5/3205 , A61M5/3213 , A61M5/3202
摘要： A needle unit comprises a needle mounted in a hub having a sleeve made from a deformable material and surrounding an end of the needle at a radial distance from that needle. The sleeve is designed to be snap-locked onto a connecting piece at the outlet end of a syringe by protrusions on the inner wall of the sleeve engaging a circumferential recess in the outer wall of the connecting piece. It is also designed such that the locking engagement between the protrusions of this sleeve and the recess of the connecting piece is released when certain zones of the outer sleeve wall are pressed inwardly. A magazine for storing the needle unit comprises a compartment which can receive the needle unit in a plurality of rotational positions. The needle unit and magazine include a syringe/needle unit release mechanism which, in a first rotational position, does not press the release zones inwardly, thereby allowing the needle unit to lock onto the syringe, but which in a second rotational position, presses the release zones inwardly so that the needle disengages from the syringe and remains inside the magazine for disposal.
摘要翻译： PCT No.PCT / DK95 / 00085 Sec。 371日期：1996年8月22日 102（e）日期1996年8月22日PCT提交1995年2月27日PCT公布。 出版物WO95 / 23005 日期1995年8月3日。一种针单元包括安装在具有由可变形材料制成的套筒并且围绕针的距离该针的径向距离处的针的毂中的针。 套筒被设计成通过套筒的内壁上的突出物与连接件的外壁中的周向凹部接合而在注射器的出口端处被卡扣锁定到连接件上。 它还被设计成使得当外套筒壁的某些区域被向内按压时，该套筒的突起与连接件的凹部之间的锁定接合被释放。 用于存储针单元的盒子包括可以以多个旋转位置接收针单元的隔室。 针单元和料仓包括注射器/针单元释放机构，其在第一旋转位置不向内按压释放区域，从而允许针单元锁定到注射器上，但是在第二旋转位置中， 向内释放区域，使针脱离注射器，并保留在刀库内进行处置。
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