摘要:
Novel leflunomide analogs were synthesized and evaluated in-vivo. Based on the in-vivo studies, these analogs are surprisingly effective for treating rheumatoid arthritis.
摘要:
A series of isoxazole derivatives and methods of suppressing, inhibiting, or preventing disorders mediated by nitric oxide (NO) and/or proinflammatory cytokines, such as TNF-α (tumor necrosis factor alpha), IL-1 (interlukin-1), and IL-6, are described.
摘要:
For the reported resveratrol analogs, the (E)-stilbene core structure is either maintained intact or only slightly modified. We use a different approach and introduced a novel heterocyclic benzothiazolium moiety into the (E)-stilbene core to form a series of novel resveratrol analogs for treating angiogenic- and/or inflammation-related disorders.
摘要:
A series of isoxazole derivatives and methods of suppressing, inhibiting, or preventing disorders mediated by nitric oxide (NO) and/or proinflammatory cytokines, such as TNF-α (tumor necrosis factor alpha), IL-1 (interlukin-1), and IL-6, are described.
摘要:
Methods of treating cancer employing isoxazole derivatives are described. Compounds and methods of using these compounds for isolating and/or detecting binding proteins, which may be indicative of a disease, are also described.
摘要:
Methods of treating cancer employing isoxazole derivatives are described. Compounds and methods of using these compounds for isolating and/or detecting binding proteins, which may be indicative of a disease, are also described.
摘要:
Disclosed are an Schisandrae fructus extract for inhibition or prevention of influenza and its application, wherein the Schisandrae fructus extract is obtained by water, methanol, or ethanol extraction process and the extract comprises compounds such as schisandrone, benzoylgomisin P, wulignan A1, epigomisin O, epiwulignan A1, and tigloylgomisin P. The extracts and purified compounds of Schisandrae fructus has anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities, therefore the extracts and the purified compounds of Schisandrae fructus can be applied as an inhitibory agent of a pharmaceutical composition for treatment or prevention agent for influenza infection.
摘要:
A traffic-control warning cone includes a hollow cone at bottom end of which a proper area extends outwards and is formed as flat bottom, then extending outwards and upwards with a certain height and formed as a circular border. A heavy body is mounted on the flat bottom so that the whole body won't be toppled and be kept in an upright state no matter how it is placed so that the present invention won't be toppled, ensures the warning effect and enhances the convenience in using.
摘要:
A connection module capable of integrating electronic control contains: a male connection assembly, a female connection assembly, and a controlling portion. The male connection assembly includes a coupling section, at least one current transmission set, at least one signal transmission set, and at least one engagement portion. The female connection assembly includes a coupling section, at least one current transmission set, at least one signal transmission set, and at least one engagement portion. The controlling portion is connected with the drive mechanism of the male connection assembly to actuate, control and detect the drive mechanism. The male connection assembly is located below the female connection assembly, and the coupling section of the female connection assembly is covered in the coupling section of the male connection assembly. The signal transmission set of the male connection assembly contacts with the signal transmission set of the female connection assembly.