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公开(公告)号：US20120315676A1
公开(公告)日：2012-12-13
申请号：US13493795
申请日：2012-06-11
申请人： Jie YANG , Andrew Shaw , Ish Kumar Dhawan , Onorato Campopiano , Kripa Rao
发明人： Jie YANG , Andrew Shaw , Ish Kumar Dhawan , Onorato Campopiano , Kripa Rao
CPC分类号： C12N9/2437 , C07K2319/02 , C12N9/2445 , C12N15/75 , C12P7/10 , C12P19/14 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , Y02E50/16
摘要： The present invention relates to variant endoglucanases and particularly endoglucanases having improved properties over wild-type endoglucanase.
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公开(公告)号：US08206960B1
公开(公告)日：2012-06-26
申请号：US13323724
申请日：2011-12-12
申请人： Jie Yang , Andrew Shaw , Ish Kumar Dhawan , Onorato Campopiano , Kripa Rao
发明人： Jie Yang , Andrew Shaw , Ish Kumar Dhawan , Onorato Campopiano , Kripa Rao
IPC分类号： C12N9/00
CPC分类号： C12N9/2437 , C07K2319/02 , C12N9/2445 , C12N15/75 , C12P7/10 , C12P19/14 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , Y02E50/16
摘要： The present invention relates to variant endoglucanases and particularly endoglucanases having improved properties over wild-type endoglucanase.
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公开(公告)号：US08663960B2
公开(公告)日：2014-03-04
申请号：US13493795
申请日：2012-06-11
申请人： Jie Yang , Andrew Shaw , Ish Kumar Dhawan , Onorato Campopiano , Kripa Rao
发明人： Jie Yang , Andrew Shaw , Ish Kumar Dhawan , Onorato Campopiano , Kripa Rao
IPC分类号： C12N9/00
CPC分类号： C12N9/2437 , C07K2319/02 , C12N9/2445 , C12N15/75 , C12P7/10 , C12P19/14 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , Y02E50/16
摘要： The present invention relates to variant endoglucanases and particularly endoglucanases having improved properties over wild-type endoglucanase.
摘要翻译： 本发明涉及与野生型内切葡聚糖酶相比具有改进性质的变体内切葡聚糖酶，特别是内切葡聚糖酶。
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公开(公告)号：US08088608B2
公开(公告)日：2012-01-03
申请号：US12751985
申请日：2010-03-31
申请人： Jie Yang , Andrew Shaw , Ish Kumar Dhawan , Onorato Campopiano , Kripa Rao
发明人： Jie Yang , Andrew Shaw , Ish Kumar Dhawan , Onorato Campopiano , Kripa Rao
IPC分类号： C12N9/00
CPC分类号： C12N9/2437 , C07K2319/02 , C12N9/2445 , C12N15/75 , C12P7/10 , C12P19/14 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , Y02E50/16
摘要： The present invention relates to variant endoglucanases and particularly endoglucanases having improved properties over wild-type endoglucanase.
摘要翻译： 本发明涉及与野生型内切葡聚糖酶相比具有改进性质的变体内切葡聚糖酶，特别是内切葡聚糖酶。
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公开(公告)号：US20120178132A1
公开(公告)日：2012-07-12
申请号：US13323724
申请日：2011-12-12
申请人： Jie Yang , Andrew Shaw , Ish Kumar Dhawan , Onorato Campopiano , Kripa Rao
发明人： Jie Yang , Andrew Shaw , Ish Kumar Dhawan , Onorato Campopiano , Kripa Rao
CPC分类号： C12N9/2437 , C07K2319/02 , C12N9/2445 , C12N15/75 , C12P7/10 , C12P19/14 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , Y02E50/16
摘要： The present invention relates to variant endoglucanases and particularly endoglucanases having improved properties over wild-type endoglucanase.
摘要翻译： 本发明涉及与野生型内切葡聚糖酶相比具有改进性质的变体内切葡聚糖酶，特别是内切葡聚糖酶。
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6.发明授权公开(公告)号：US08298795B2
公开(公告)日：2012-10-30
申请号：US13215193
申请日：2011-08-22
申请人： Jie Yang , Louis Clark , Onorato Campopiano , Kripa Rao , Lorand Szabo , Janos Torok , Dipnath Baidyaroy
发明人： Jie Yang , Louis Clark , Onorato Campopiano , Kripa Rao , Lorand Szabo , Janos Torok , Dipnath Baidyaroy
CPC分类号： C12P19/02 , C12N9/242 , C12N9/2434 , C12P7/10 , C12P7/14 , C12P19/14 , Y02E50/16 , Y02P20/52
摘要： The invention provides recombinant GH61 proteins obtained from Myceliophtora thermophila, and nucleic acids that encode such proteins. The invention also provides protein fractions isolated from M. thermophila supernatant that have GH61 protein activity. These preparations can be used to increase yield of products from reactions in which a cellulose-containing substrate undergoes saccharification by one or more cellulase enzymes, such as endoglucanase, β-glucosidase, or cellobiohydrolase. Combinations of GH61 protein and cellulases can be used to break down cellulosic biomass into fermentable sugars in the production of ethanol.
摘要翻译： 本发明提供了从嗜热丝霉菌（Myceliophtora thermophila）获得的重组GH61蛋白质和编码这种蛋白质的核酸。 本发明还提供从具有GH61蛋白活性的嗜热绵羊嗜热上清液分离的蛋白质级分。 可以使用这些制剂从含有纤维素的底物通过一种或多种纤维素酶如内切葡聚糖酶，葡糖苷酶或纤维二糖水解酶进行糖化的反应来提高产品的产量。 GH61蛋白和纤维素酶的组合可用于在生产乙醇中将纤维素生物质分解成可发酵糖。
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7.发明授权Use of glycohydrolase 61 protein variants with improved thermostability for processing cellulose 有权使用具有改善热稳定性的糖水解酶61蛋白质变体来加工纤维素公开(公告)号：US09493802B2
公开(公告)日：2016-11-15
申请号：US13640471
申请日：2011-08-22
申请人： Jie Yang , Louis Clark , Onorato Campopiano , Kripa Rao , Lorand Szabo , Janos Torok , Dipnath Baidyaroy
发明人： Jie Yang , Louis Clark , Onorato Campopiano , Kripa Rao , Lorand Szabo , Janos Torok , Dipnath Baidyaroy
CPC分类号： C12P19/02 , C12N9/242 , C12N9/2434 , C12P7/10 , C12P7/14 , C12P19/14 , Y02E50/16 , Y02P20/52
摘要： The invention provides recombinant GH61 proteins obtained from Myceliophtora thermophila, and nucleic acids that encode such proteins. The invention also provides protein fractions isolated from M. thermophila supernatant that have GH61 protein activity. These preparations can be used to increase yield of products from reactions in which a cellulose-containing substrate undergoes saccharification by one or more cellulase enzymes, such as endoglucanase, β-glucosidase, or cellobiohydrolase. Combinations of GH61 protein and cellulases can be used to break down cellulosic biomass into fermentable sugars in the production of ethanol.
摘要翻译： 本发明提供了从嗜热丝霉菌（Myceliophtora thermophila）获得的重组GH61蛋白质和编码这种蛋白质的核酸。 本发明还提供从具有GH61蛋白活性的嗜热绵羊嗜热上清液分离的蛋白质级分。 可以使用这些制剂从含有纤维素的底物通过一种或多种纤维素酶如内切葡聚糖酶，β-葡糖苷酶或纤维二糖水解酶进行糖化的反应来提高产品的产量。 GH61蛋白和纤维素酶的组合可用于在生产乙醇中将纤维素生物质分解成可发酵糖。
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8.发明申请公开(公告)号：US20140186896A1
公开(公告)日：2014-07-03
申请号：US13640471
申请日：2011-08-22
申请人： Jie Yang , Louis Clark , Onorato Campopiano , Kripa Rao , Lorand Szabo , Janos Torok , Dipnath Baidyaroy
发明人： Jie Yang , Louis Clark , Onorato Campopiano , Kripa Rao , Lorand Szabo , Janos Torok , Dipnath Baidyaroy
CPC分类号： C12P19/02 , C12N9/242 , C12N9/2434 , C12P7/10 , C12P7/14 , C12P19/14 , Y02E50/16 , Y02P20/52
摘要： The invention provides recombinant GH61 proteins obtained from Myceliophtora thermophila, and nucleic acids that encode such proteins. The invention also provides protein fractions isolated from M. thermophila supernatant that have GH61 protein activity. These preparations can be used to increase yield of products from reactions in which a cellulose-containing substrate undergoes saccharification by one or more cellulase enzymes, such as endoglucanase, β-glucosidase, or cellobiohydrolase. Combinations of GH61 protein and cellulases can be used to break down cellulosic biomass into fermentable sugars in the production of ethanol.
摘要翻译： 本发明提供了从嗜热丝霉菌（Myceliophtora thermophila）获得的重组GH61蛋白质和编码这种蛋白质的核酸。 本发明还提供从具有GH61蛋白活性的嗜热绵羊嗜热上清液分离的蛋白质级分。 可以使用这些制剂从含有纤维素的底物通过一种或多种纤维素酶如内切葡聚糖酶，葡糖苷酶或纤维二糖水解酶进行糖化的反应来提高产品的产量。 GH61蛋白和纤维素酶的组合可用于在生产乙醇中将纤维素生物质分解成可发酵糖。
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9.发明申请公开(公告)号：US20120083019A1
公开(公告)日：2012-04-05
申请号：US13215193
申请日：2011-08-22
申请人： Dipnath Baidyaroy , Louis Clark , Onorato Campopiano , Kripa Rao , Lorand Szabo , Janos Torok
发明人： Dipnath Baidyaroy , Louis Clark , Onorato Campopiano , Kripa Rao , Lorand Szabo , Janos Torok
CPC分类号： C12P19/02 , C12N9/242 , C12N9/2434 , C12P7/10 , C12P7/14 , C12P19/14 , Y02E50/16 , Y02P20/52
摘要： The invention provides recombinant GH61 proteins obtained from Myceliophtora thermophila, and nucleic acids that encode such proteins. The invention also provides protein fractions isolated from M. thermophila supernatant that have GH61 protein activity. These preparations can be used to increase yield of products from reactions in which a cellulose-containing substrate undergoes saccharification by one or more cellulase enzymes, such as endoglucanase, β-glucosidase, or cellobiohydrolase. Combinations of GH61 protein and cellulases can be used to break down cellulosic biomass into fermentable sugars in the production of ethanol.
摘要翻译： 本发明提供了从嗜热丝霉菌（Myceliophtora thermophila）获得的重组GH61蛋白质和编码这种蛋白质的核酸。 本发明还提供从具有GH61蛋白活性的嗜热绵羊嗜热上清液分离的蛋白质级分。 可以使用这些制剂从含有纤维素的底物通过一种或多种纤维素酶如内切葡聚糖酶，葡糖苷酶或纤维二糖水解酶进行糖化的反应来提高产品的产量。 GH61蛋白和纤维素酶的组合可用于在生产乙醇中将纤维素生物质分解成可发酵糖。
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10.发明申请公开(公告)号：US20120231510A1
公开(公告)日：2012-09-13
申请号：US13508691
申请日：2010-11-18
申请人： Kripa Rao , Ish Dhawan , Sally Postlethwaite , Jie Yang
发明人： Kripa Rao , Ish Dhawan , Sally Postlethwaite , Jie Yang
CPC分类号： C12P19/02 , C12N9/2437 , C12N9/2445 , C12P7/10 , C12P19/14 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , Y02E50/16
摘要： The invention relates to a multi-cellulase enzyme composition for the enzymatic hydrolysis of cellulosic biomass said composition comprising a cellobiohydrolase (CBH) enzyme, an endoglucanase (EG) enzyme and a β-glucosidase (BG) enzyme.
摘要翻译： 本发明涉及用于纤维素生物质的酶水解的多纤维素酶组合物，所述组合物包含纤维二糖水解酶（CBH）酶，内切葡聚糖酶（EG）酶和葡糖苷酶（BG）酶。
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