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公开(公告)号：US08491942B2
公开(公告)日：2013-07-23
申请号：US13394957
申请日：2010-10-15
申请人： Jin Auh , Chang-Kyun Han , Young-June Shin , Hyo-Jin Moon , Jong-Wook Lee , Tae-Hoo Yi , Kang-Jin Lee , Kang-Hyun Leem
发明人： Jin Auh , Chang-Kyun Han , Young-June Shin , Hyo-Jin Moon , Jong-Wook Lee , Tae-Hoo Yi , Kang-Jin Lee , Kang-Hyun Leem
IPC分类号： A01N65/00
CPC分类号： A61K36/718 , A23L2/52 , A23L33/105 , A23V2002/00 , A61K9/0053 , A61K36/39 , A61K2300/00 , A23V2250/702 , A23V2250/712 , A23V2250/704 , A23V2250/21 , A23V2250/708 , A23V2250/156 , A23V2200/306 , A23V2250/032 , A23V2250/28 , A23V2250/0644
摘要： A use an extract of Coptidis Rhizoma or a combined extract of Coptidis Rhizoma and Pharbitidis Semen as an active ingredient for preventing and/or treating periodontal disease is provided. The extract of Coptidis Rhizoma or a combined extract of Coptidis Rhizoma and Pharbitidis Semen has activities to stimulate anti-inflammation, osteoblast differentiation and alveolar bone regeneration, and to prevent the alveolar bone destruction, thereby being effective for the prevention and/or treatment of periodontal disease.
摘要翻译： 提供使用黄连提取物或黄连提取物和麻黄精液的组合提取物作为预防和/或治疗牙周病的活性成分。 黄连提取物或黄连提取物和麻黄碱提取物具有刺激抗炎，成骨细胞分化和牙槽骨再生的作用，并防止牙槽骨破坏，从而有效预防和/或治疗牙周病 疾病。
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公开(公告)号：US20120195986A1
公开(公告)日：2012-08-02
申请号：US13394957
申请日：2010-10-15
申请人： Jin Auh , Chang-Kyun Han , Young-June Shin , Hyo-Jin Moon , Jong-Wook Lee , Tae-Hoo Yi , Kang-Jin Lee , Kang-Hyun Leem
发明人： Jin Auh , Chang-Kyun Han , Young-June Shin , Hyo-Jin Moon , Jong-Wook Lee , Tae-Hoo Yi , Kang-Jin Lee , Kang-Hyun Leem
CPC分类号： A61K36/718 , A23L2/52 , A23L33/105 , A23V2002/00 , A61K9/0053 , A61K36/39 , A61K2300/00 , A23V2250/702 , A23V2250/712 , A23V2250/704 , A23V2250/21 , A23V2250/708 , A23V2250/156 , A23V2200/306 , A23V2250/032 , A23V2250/28 , A23V2250/0644
摘要： A use an extract of Coptidis Rhizoma or a combined extract of Coptidis Rhizoma and Pharbitidis Semen as an active ingredient for preventing and/or treating periodontal disease is provided. The extract of Coptidis Rhizoma or a combined extract of Coptidis Rhizoma and Pharbitidis Semen has activities to stimulate anti-inflammation, osteoblast differentiation and alveolar bone regeneration, and to prevent the alveolar bone destruction, thereby being effective for the prevention and/or treatment of periodontal disease.
摘要翻译： 提供使用黄连提取物或黄连提取物和麻黄精液的组合提取物作为预防和/或治疗牙周病的活性成分。 黄连提取物或黄连提取物和麻黄碱提取物具有刺激抗炎，成骨细胞分化和牙槽骨再生的作用，并防止牙槽骨破坏，从而有效预防和/或治疗牙周病 疾病。
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3.发明申请PHARMACEUTICAL COMPOSITION CONTAINING HERBAL EXTRACT FOR PREVENTION OR TREATMENT OF NEPHRITIS 有权含有草药提取物的药物组合物用于预防或治疗非传染性疾病公开(公告)号：US20120070517A1
公开(公告)日：2012-03-22
申请号：US13375255
申请日：2010-06-01
申请人： Jin Auh , Chang-Hwan Kim , Chang-Kyun Han , Sung-Hum Yeon , Seung-In Choe , Young-June Shin , Dong-Oh Han , Soo-Im Chang , Ji-Hye Lee , Jun-Seok Lee , Ho-Young Kwak , Hyo-Jin Moon , Jong-Wook Lee , Sung-Min Kim
发明人： Jin Auh , Chang-Hwan Kim , Chang-Kyun Han , Sung-Hum Yeon , Seung-In Choe , Young-June Shin , Dong-Oh Han , Soo-Im Chang , Ji-Hye Lee , Jun-Seok Lee , Ho-Young Kwak , Hyo-Jin Moon , Jong-Wook Lee , Sung-Min Kim
IPC分类号： A61K36/734 , A61P29/00 , A61P13/12
CPC分类号： A61K36/734 , A61K36/11 , A61K36/536 , A61K36/54 , A61K36/73 , A61K2300/00
摘要： The present invention relates to a novel use of herbal extracts in a pharmaceutical composition for prevention and treatment of nephritis and, more particularly, to a pharmaceutical composition and a health functional food for prevention and/or treatment of nephritis that contains at least one herbal extract selected from the group consisting of a Crataegi Fructus extract, a Cinnamomi Cortex extract, a Prunella Spica extract, and an Equiseti Herba extract, a method for prevention and/or treatment of nephritis using the herbal extract, and a use of the herbal extract in preparation of a composition for prevention and/or treatment of nephritis. The herbal extract has a good therapeutic effect for nephritis on a nephritis model of which the nephritis is induced by a drug such as gentamicin, cisplatin, etc., and a good inhibitory activity on the growth of mesangial cells in kidneys, thereby providing a very useful means for prevention and/or treatment of nephritis.
摘要翻译： 本发明涉及草药提取物在用于预防和治疗肾炎的药物组合物中的新用途，更具体地，涉及含有至少一种草药提取物的用于预防和/或治疗肾炎的药物组合物和健康功能食品 选自Crataegi Fructus提取物，Cinnamomi Cortex提取物，Prunella Spica提取物和Equiseti Herba提取物，使用草药提取物预防和/或治疗肾炎的方法，以及使用草药提取物 制备用于预防和/或治疗肾炎的组合物。 草药提取物对肾炎的治疗效果良好，肾炎是由庆大霉素，顺铂等药物引起的肾炎引起的，对肾脏肾小球膜细胞生长具有良好的抑制活性， 预防和/或治疗肾炎的有用手段。
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4.发明授权Pharmaceutical composition containing herbal extract for prevention or treatment of nephritis 有权含有用于预防或治疗肾炎的草药提取物的药物组合物公开(公告)号：US08642096B2
公开(公告)日：2014-02-04
申请号：US13375255
申请日：2010-06-01
申请人： Jin Auh , Chang-Hwan Kim , Chang-Kyun Han , Sung-Hum Yeon , Seung-In Choe , Young-June Shin , Dong-Oh Han , Soo-Im Chang , Ji-Hye Lee , Jun-Seok Lee , Ho-Young Kwak , Hyo-Jin Moon , Jong-Wook Lee , Sung-Min Kim
发明人： Jin Auh , Chang-Hwan Kim , Chang-Kyun Han , Sung-Hum Yeon , Seung-In Choe , Young-June Shin , Dong-Oh Han , Soo-Im Chang , Ji-Hye Lee , Jun-Seok Lee , Ho-Young Kwak , Hyo-Jin Moon , Jong-Wook Lee , Sung-Min Kim
IPC分类号： A01N65/00
CPC分类号： A61K36/734 , A61K36/11 , A61K36/536 , A61K36/54 , A61K36/73 , A61K2300/00
摘要： The present invention relates to a novel use of herbal extracts in a pharmaceutical composition for prevention and treatment of nephritis and, more particularly, to a pharmaceutical composition and a health functional food for prevention and/or treatment of nephritis that contains at least one herbal extract selected from the group consisting of a Crataegi Fructus extract, a Cinnamomi Cortex extract, a Prunella Spica extract, and an Equiseti Herba extract, a method for prevention and/or treatment of nephritis using the herbal extract, and a use of the herbal extract in preparation of a composition for prevention and/or treatment of nephritis. The herbal extract has a good therapeutic effect for nephritis on a nephritis model of which the nephritis is induced by a drug such as gentamicin, cisplatin, etc., and a good inhibitory activity on the growth of mesangial cells in kidneys, thereby providing a very useful means for prevention and/or treatment of nephritis.
摘要翻译： 本发明涉及草药提取物在用于预防和治疗肾炎的药物组合物中的新用途，更具体地，涉及含有至少一种草药提取物的用于预防和/或治疗肾炎的药物组合物和健康功能食品 选自Crataegi Fructus提取物，Cinnamomi Cortex提取物，Prunella Spica提取物和Equiseti Herba提取物，使用草药提取物预防和/或治疗肾炎的方法，以及使用草药提取物 制备用于预防和/或治疗肾炎的组合物。 草药提取物对肾炎的治疗效果良好，肾炎是由庆大霉素，顺铂等药物引起的肾炎引起的，对肾脏肾小球膜细胞生长具有良好的抑制活性， 预防和/或治疗肾炎的有用手段。
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5.发明申请Extract of Coptidis Rhizoma and novel use thereof in treating respiratory disease 有权黄连提取物及其在治疗呼吸系统疾病中的新用途公开(公告)号：US20110081434A1
公开(公告)日：2011-04-07
申请号：US12996646
申请日：2009-06-12
申请人： Jin Auh , Chang-Hwan Kim , Chang-Kyun Han , Sung-Hum Yeon , Young-June Shin , Min-Ki Shin , Soo-Im Chang
发明人： Jin Auh , Chang-Hwan Kim , Chang-Kyun Han , Sung-Hum Yeon , Young-June Shin , Min-Ki Shin , Soo-Im Chang
CPC分类号： A61K36/718 , A61K36/25 , A61K2300/00
摘要： A composition for suppressing cough, removing sputum, preventing and/or treating a respiratory disease comprising an extract of Coptidis rhizoma or a combined extract of Coptidis rhizoma with ivy leaf as an active ingredient, and a method of suppressing cough, removing sputum, and/or preventing and/or treating respiratory disease using the composition, are provided.
摘要翻译： 抑制咳嗽，清除痰液，预防和/或治疗呼吸系统疾病的组合物，其中包括黄连提取物或黄连提取物与常春藤叶作为有效成分的组合提取物，以及抑制咳嗽，除痰和/ 或使用该组合物预防和/或治疗呼吸系统疾病。
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公开(公告)号：US08425953B2
公开(公告)日：2013-04-23
申请号：US12996646
申请日：2009-06-12
申请人： Jin Auh , Chang-Hwan Kim , Chang-Kyun Han , Sung-Hum Yeon , Young-June Shin , Min-Ki Shin , Soo-Im Chang
发明人： Jin Auh , Chang-Hwan Kim , Chang-Kyun Han , Sung-Hum Yeon , Young-June Shin , Min-Ki Shin , Soo-Im Chang
IPC分类号： A61K36/00
CPC分类号： A61K36/718 , A61K36/25 , A61K2300/00
摘要： A composition for suppressing cough, removing sputum, preventing and/or treating a respiratory disease comprising an extract of Coptidis rhizoma or a combined extract of Coptidis rhizoma with ivy leaf as an active ingredient, and a method of suppressing cough, removing sputum, and/or preventing and/or treating respiratory disease using the composition, are provided.
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7.发明申请公开(公告)号：US20070249711A1
公开(公告)日：2007-10-25
申请号：US10575384
申请日：2004-10-11
申请人： Wonrack Choi , Chang-Kyun Han , Tae Kim , Guang-Jin Im , Chil Jung , Se Yun , Bongcheol Kim , Soomin Lee , Wie-Jong Kwak
发明人： Wonrack Choi , Chang-Kyun Han , Tae Kim , Guang-Jin Im , Chil Jung , Se Yun , Bongcheol Kim , Soomin Lee , Wie-Jong Kwak
CPC分类号： A23L33/10 , A23V2002/00 , A61K31/56 , A23V2200/322 , A23V2250/2124 , A23V2250/214 , A23V2250/708 , A23V2250/712 , A23V2250/1592 , A23V2250/1642
摘要： The present invention relates to the triterpene compounds improving in brain functions. In particular, the present invention relates to a novel use of the triterpene compounds represented by the Formula 1 for improving decreased memory and a pharmaceutical composition for improving brain functions comprising the triterpene compounds represented by the Formula 1.
摘要翻译： 本发明涉及改善脑功能的三萜化合物。 特别地，本发明涉及由式1表示的三萜化合物用于改善记忆力的改善和用于改善脑功能的药物组合物的新用途，其包括由式1表示的三萜烯化合物。
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公开(公告)号：US08652537B2
公开(公告)日：2014-02-18
申请号：US13400784
申请日：2012-02-21
申请人： Chang-Kyun Han , Wie-Jong Kwak , Ki Won Joung , Hun Seung Yoo , Do Seung Kum , Yong-Baik Cho , Keun Ho Ryu , Hae In Rhee , Taek Su Kim , In Ho Jung , So Yoon Lee , Jung Bum Yi , Joo Hyon Kim , Key An Um
发明人： Chang-Kyun Han , Wie-Jong Kwak , Ki Won Joung , Hun Seung Yoo , Do Seung Kum , Yong-Baik Cho , Keun Ho Ryu , Hae In Rhee , Taek Su Kim , In Ho Jung , So Yoon Lee , Jung Bum Yi , Joo Hyon Kim , Key An Um
IPC分类号： A61K36/00
CPC分类号： A61K36/536 , A61K36/428 , A61K36/716 , A61K2300/00
摘要： The present invention relates to a herbal drug composition for cartilage protection comprising plant extracts of Clematis Radix, Trichosanthis Radix, and Prunellae Spica and an optimal content of rosmarinic acid to: (i) alleviate pains; (ii) inhibit the acute/chronic inflammation, platelet/whole blood aggregation, immunocyte (B-lymphcyte and T-lymphcyte) proliferation, inflammation-inducing enzyme activities, and enzyme activities associated with degradation of joint tissue; (iii) scavenge activity of toxic active oxygen radicals; and (iv) further provide excellent cartilage protection activity to be effectively used as an anti-inflammatory agent with analgesic effects, blood circulation enhancer, arthritis therapeutic agent and cartilage protective.
摘要翻译： 本发明涉及一种用于软骨保护的草药组合物，其包括铁线莲（Trichosanthis Radix），夏枯草（Prunellae Spica）的植物提取物和迷迭香酸的最佳含量，以：（i）缓解疼痛; （ii）抑制急性/慢性炎症，血小板/全血聚集，免疫细胞（B淋巴细胞和T淋巴细胞）增殖，炎症诱导酶活性和与关节组织降解相关的酶活性; （iii）有毒活性氧自由基的清除活性; 和（iv）进一步提供优异的软骨保护活性，有效地用作镇痛作用的抗炎药，血液循环增强剂，关节炎治疗剂和软骨保护。
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公开(公告)号：US20080248143A1
公开(公告)日：2008-10-09
申请号：US11883612
申请日：2005-02-03
申请人： Wonrack Choi , Chang-Kyun Han , Jung-Woo Seo , Guang-Jin Im , Chilmann Jung , Se Jun Yun , Wie-Jong Kwak , Tae Kon Kim , Bongcheol Kim , Soomin Lee
发明人： Wonrack Choi , Chang-Kyun Han , Jung-Woo Seo , Guang-Jin Im , Chilmann Jung , Se Jun Yun , Wie-Jong Kwak , Tae Kon Kim , Bongcheol Kim , Soomin Lee
CPC分类号： A61K36/71
摘要： This invention relates to Pulsatillae Radix extract for improving brain functions. More specifically, this invention relates to Pulsatillae Radix extract, its active fractions and a pharmaceutical product and a health food containing the same respectively having a protective activity against neurotoxicity and a growth inhibitory effect induced by beta-amyloid, an anti-oxidizing effect, a neuron proliferating effect and improving memory thereby effective in improving brain functions such as Mild Cognitive Impairment and dementia.
摘要翻译： 本发明涉及白头翁提取物，用于改善脑功能。 更具体地，本发明涉及白头翁提取物，其活性成分和药物，以及含有分别具有抗神经毒性的保护活性和由β-淀粉样蛋白诱导的生长抑制作用的保健食品的保健食品，抗氧化作用， 神经元增殖效应和提高记忆力，从而有效改善脑功能，如轻度认知障碍和痴呆。
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公开(公告)号：US20050271750A1
公开(公告)日：2005-12-08
申请号：US10523854
申请日：2003-08-12
申请人： Soon Lee , Wie-Jong Kwak , Chang-Kyun Han , Joo Kim
发明人： Soon Lee , Wie-Jong Kwak , Chang-Kyun Han , Joo Kim
IPC分类号： A61K9/06 , A61K8/00 , A61K8/92 , A61K8/96 , A61K8/97 , A61K9/70 , A61K36/00 , A61K36/14 , A61K36/48 , A61K36/71 , A61K36/718 , A61P17/10 , A61P17/12 , A61P29/00 , A61P31/04 , A61P43/00 , A61Q17/00 , A61Q19/00 , A61Q19/10 , A61K35/78
CPC分类号： A61Q19/00 , A61K8/97 , A61K36/14 , A61K36/48 , A61K36/718 , A61K2800/782
摘要： Disclosed is a topical formulation for preventing or treating acne, in particular to a topical formulation for preventing or treating acne through the antimicrobial activity of the formulation against acne-causing bacteria, Propionibacterium acnes, inhibition of excess production of sebum by inhibition of excess production of sebum by inhibition of 5α-reductase, inhibition of comedo, keratolysis and anti-inflammatory action, which comprises extract obtained from at least one oriental medicine selected from the group consisting of Cavalia gladiata, Biota orientalis and Coptis chinensis.
摘要翻译： 公开了一种用于预防或治疗痤疮的局部制剂，特别是用于通过制剂的抗微生物活性预防或治疗痤疮的局部制剂，以防止痤疮引起的细菌，丙酸杆菌，抑制过量产生皮脂过多产生皮脂 抑制5α-还原酶，抑制喜剧，角质溶解和抗炎作用的皮脂，其包含从至少一种选自Cavalia gladiata，Biota orientalis和Coptis chinensis的东方药物获得的提取物。
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