PHARMACEUTICAL COMPOSITIONS AND METHODS OF DELIVERING THE SAME
    3.
    发明申请
    PHARMACEUTICAL COMPOSITIONS AND METHODS OF DELIVERING THE SAME 审中-公开
    药物组合物及其递送方法

    公开(公告)号:US20110146671A1

    公开(公告)日:2011-06-23

    申请号:US11944616

    申请日:2007-11-24

    摘要: The present invention provides a pharmaceutical composition comprising a chemical compound or a herb extract or the combination having at least one of the activities of antiviral, antibacterial, antifungal, anti-inflammatory, anti-allergy, anti-cancer, promoting membrane healing or immunomodulating, for the treatment and prevention of a disease of a mammal. The present invention also provides a system for delivering the composition to the hard-to-reach sinuses of a mammal to reduce the load of the pathogen, to reduce the amount of inflammatory mediators, to heal pathological changes, and collectively to treat a disease of a mammal, such as allergic fungal rhinosinusitis. The invented method of treating a human disease reduces infectious and inflammatory agents without causing antibiotic resistance or adverse event. The present invention additionally provides a kit for collecting the nasal wash specimen to analyze how much drug is administered into sinonasal cavities or to determine the load of microbes in rhino-sinuses.

    摘要翻译: 本发明提供一种药物组合物,其包含化合物或草药提取物或具有抗病毒,抗菌,抗真菌,抗炎,抗过敏,抗癌,促进膜愈合或免疫调节中的至少一种活性的组合, 用于治疗和预防哺乳动物的疾病。 本发明还提供了一种用于将组合物递送到哺乳动物难以达到的鼻窦的系统,以减少病原体的负荷,减少炎症介质的量,治愈病理变化,以及共同治疗疾病的 哺乳动物,如过敏性真菌性鼻鼻窦炎。 本发明的治疗人类疾病的方法减少感染性和炎症因素,而不引起抗生素抗性或不良事件。 本发明另外提供了一种用于收集鼻洗液样本的试剂盒,以分析将多少药物施用于鼻腔或确定犀牛中微生物的负荷。

    Composition and pharmaceutical preparation containing same for the treatment of herpes and related viral infections
    6.
    发明申请
    Composition and pharmaceutical preparation containing same for the treatment of herpes and related viral infections 审中-公开
    含有其的治疗疱疹和相关病毒感染的组合物和药物制剂

    公开(公告)号:US20030215529A1

    公开(公告)日:2003-11-20

    申请号:US10265354

    申请日:2002-10-04

    IPC分类号: A61K035/78

    CPC分类号: A61K36/536

    摘要: In accordance with the present invention, novel compositions useful for the treatment of the cytopathogenic effects of an enveloped virus in mammals have been discovered by extraction and purification from the spikes of Prunella vulgaris. In particular, invention compositions comprise a lignin-carbohydrate complex as an active ingredient for inhibition of viral infection in a mammal. In accordance with an embodiment of the present invention, it has been discovered that invention compositions are effective agents for the prophylaxis and therapy in mammals of diseases caused by enveloped viruses, e.g., herpes simplex virus. Methods for producing invention compositions and uses therefor are also provided.

    摘要翻译: 根据本发明,通过从普通寻常the the的提取和纯化已经发现了可用于治疗哺乳动物中包膜病毒细胞致病作用的新型组合物。 特别地,本发明组合物包含木质素 - 碳水化合物复合物作为抑制哺乳动物病毒感染的活性成分。 根据本发明的实施方案,已经发现本发明组合物是用于预防和治疗由包膜病毒(例如单纯疱疹病毒)引起的疾病的哺乳动物的有效试剂。 还提供了用于制备本发明组合物及其用途的方法。