公开(公告)号：US20070092445A1

公开(公告)日：2007-04-26

申请号：US11530718

申请日：2006-09-11

申请人： John Coley ,  Fernando Miro ,  Jayne Ellis ,  Paul Henry Mundill

发明人： John Coley ,  Fernando Miro ,  Jayne Ellis ,  Paul Henry Mundill

IPC分类号： A61K49/00 ,  G01N33/567

CPC分类号： G01N33/76

摘要： Methods for assessing the ovarian reserve of a female subject may include (a) testing the concentration of follicle stimulating hormone (FSH) in urine samples obtained from the subject, the samples being obtained on at least two different days during a first menstrual cycle in the subject; (b) testing the concentration of FSH in further urine samples, the further samples being obtained on at least two different days during one or more subsequent menstrual cycles in the subject, which days may be the same as, or different from, the days on which samples are obtained in step (a); (c) comparing the FSH test results obtained from the subject with a reference value calculated from a menopausal or non-menopausal control population; and, (d) based at least partly on the comparison, making an assessment of the subject's ovarian reserve

摘要翻译： 用于评估女性受试者卵巢储备的方法可以包括（a）在从受试者获得的尿液样本中测试促卵泡激素（FSH）的浓度，所述样品在第一次月经周期中在至少两个不同的日期获得 学科; （b）测试其他尿液样本中的FSH浓度，另外的样品是在受试者的一个或多个随后的月经周期中至少两个不同的日期获得的，这些天可以与天数相同或不同 在步骤（a）中获得样品; （c）将从受试者获得的FSH测试结果与从绝经或非绝经对照组计算的参考值进行比较; 和（d）至少部分地基于比较，对主体的卵巢储备进行评估

公开(公告)号：US20050130311A1

公开(公告)日：2005-06-16

申请号：US10489908

申请日：2002-09-18

申请人： John Coley ,  Fernando Miro ,  Laurence Aspinall ,  Peter Murray ,  Anthony Dadd ,  Zhi Zhang ,  Paul Mundill

发明人： John Coley ,  Fernando Miro ,  Laurence Aspinall ,  Peter Murray ,  Anthony Dadd ,  Zhi Zhang ,  Paul Mundill

IPC分类号： G01N33/74 ,  G01N33/76 ,  G01N33/00

CPC分类号： G01N33/74 ,  G01N33/76

摘要： Disclosed is a method of detecting a retarded cycle in a human female subject experiencing same, the method comprising the steps of obtaining a sample of body fluid from the subject on each of a plurality of, but not less than three, days; testing each of the plurality of samples to determine the concentration therein of at least one analyte of significance in the ovulatory cycle; comparing a result determined from said testing with a predetermined threshold value; and, if said determined result is different from the threshold value; declaring the cycle, during which the samples were taken, to be a retarded cycle.

摘要翻译： 本发明公开了一种在经历其的人类女性受试者中检测延迟循环的方法，所述方法包括以下步骤：从多个但不少于三天的每一天获得受试者的体液样品; 测试所述多个样品中的每一个以确定在排卵周期中至少一种有意义的分析物的浓度; 将从所述测试确定的结果与预定阈值进行比较; 并且如果所述确定结果不同于所述阈值; 宣布将采样的周期作为延迟周期。