公开(公告)号：US20070092445A1

公开(公告)日：2007-04-26

申请号：US11530718

申请日：2006-09-11

申请人： John Coley ,  Fernando Miro ,  Jayne Ellis ,  Paul Henry Mundill

发明人： John Coley ,  Fernando Miro ,  Jayne Ellis ,  Paul Henry Mundill

IPC分类号： A61K49/00 ,  G01N33/567

CPC分类号： G01N33/76

摘要： Methods for assessing the ovarian reserve of a female subject may include (a) testing the concentration of follicle stimulating hormone (FSH) in urine samples obtained from the subject, the samples being obtained on at least two different days during a first menstrual cycle in the subject; (b) testing the concentration of FSH in further urine samples, the further samples being obtained on at least two different days during one or more subsequent menstrual cycles in the subject, which days may be the same as, or different from, the days on which samples are obtained in step (a); (c) comparing the FSH test results obtained from the subject with a reference value calculated from a menopausal or non-menopausal control population; and, (d) based at least partly on the comparison, making an assessment of the subject's ovarian reserve

摘要翻译： 用于评估女性受试者卵巢储备的方法可以包括（a）在从受试者获得的尿液样本中测试促卵泡激素（FSH）的浓度，所述样品在第一次月经周期中在至少两个不同的日期获得 学科; （b）测试其他尿液样本中的FSH浓度，另外的样品是在受试者的一个或多个随后的月经周期中至少两个不同的日期获得的，这些天可以与天数相同或不同 在步骤（a）中获得样品; （c）将从受试者获得的FSH测试结果与从绝经或非绝经对照组计算的参考值进行比较; 和（d）至少部分地基于比较，对主体的卵巢储备进行评估

公开(公告)号：US07141212B2

公开(公告)日：2006-11-28

申请号：US08338141

申请日：1994-11-09

申请人： Michael Catt ,  Paul Henry Mundill ,  Michael Evans Prior

发明人： Michael Catt ,  Paul Henry Mundill ,  Michael Evans Prior

IPC分类号： G01N21/00

CPC分类号： G01N21/8483 ,  B01L3/5023 ,  B01L2200/12 ,  B01L2300/0825 ,  B01L2400/0406 ,  G01N2021/8618 ,  G01N2021/8654 ,  G01N2201/06153 ,  G01N2201/0696

摘要： A method of “reading” the result of an assay effected by concentrating a detectable material in a comparatively small zone of a carrier in the form of a strip, sheet or layer through the thickness of which electromagnetic radiation such as visible light is transmissible, wherein at least a portion of one face or the carrier is exposed to incident electromagnetic radiation which is substantially uniform across the entire portion, the portion including the small zone, and electromagnetic radiation emerging from the opposite face of the carrier is measured to determine the assay result. Preferably the radiation is diffuse light.

摘要翻译： 通过将可检测材料集中在带状，片状或层状形式的载体的相对小的区域中，通过将电磁辐射如可见光透射的厚度集中在其中，“读取”测定结果的方法，其中 一个面或载体的至少一部分暴露于跨越整个部分基本均匀的入射电磁辐射，测量包括小区域的部分和从载体的相对面出射的电磁辐射以确定测定结果 。 优选地，辐射是漫射光。

公开(公告)号：US06235241B1

公开(公告)日：2001-05-22

申请号：US09078501

申请日：1998-05-14

申请人： Michael Catt ,  Paul Henry Mundill ,  Michael Evans Prior

发明人： Michael Catt ,  Paul Henry Mundill ,  Michael Evans Prior

IPC分类号： G01N2100

CPC分类号： B01L3/5023 ,  B01L2200/12 ,  B01L2300/0825 ,  B01L2400/0406 ,  G01N21/8483 ,  G01N2021/8618 ,  G01N2021/8654 ,  G01N2201/06153 ,  G01N2201/0696

摘要： An assay result reader, for use in conjunction with an assay device comprising a porous liquid-permeable carrier in the form of a strip or sheet through the thickness of which electromagnetic radiation is transmissible, the carrier including a detection zone in which an assay result is revealed by specific binding of a detectable material directly or indirectly to a binding agent immobilized in the detection zone, detection of the detectable material being effected by determining the extent to which electromagnetic radiation transmitted through the thickness of said carrier is attenuated by the presence of the detectable material bound in the detection zone.

摘要翻译： 测定结果读取器，用于与测定装置结合使用，所述测定装置包括通过电磁辐射可传播的厚度的带状或片状形式的多孔液体可渗透载体，所述载体包括检测区域，其中测定结果为 通过将可检测材料直接或间接地特异性结合到固定在检测区中的结合剂来显示，可检测材料的检测是通过确定通过所述载体的厚度传输的电磁辐射的程度通过存在 在检测区域中结合的可检测材料。