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1.发明授权Sterile formed, filled and sealed flexible container and draining administration port therefor 失效无菌形成，填充密封的柔性容器和排水管理端口公开(公告)号：US06280431B1
公开(公告)日：2001-08-28
申请号：US09178323
申请日：1998-10-23
IPC分类号： A61B1900
CPC分类号： A61J1/10 , A61J1/1406 , Y10S604/905
摘要： A formed, filled, and sealed flexible container is provided with an attached port assembly. The container is formed from film folded to define opposing sidewalls which are sealed to define a chamber for sterile fluid. A hollow, tubular port member is provided with a V-shaped saddle and is sealed to the bottom of the container. The film at the bottom of the container is received in the saddle. A unique shoulder is defined by the tubular port member. The film is sealed to the shoulder and to the saddle of the port member. A hollow penetrator element is slidably disposed within the port member and is movable between a retracted position and an advanced position to puncture the film whereby fluid can flow out of the container. Internal formations are provided to guide and to limit the movement of the penetrator element. The container film may be provided with a crease along the bottom of the container.
摘要翻译： 形成的，填充的和密封的柔性容器设置有附接的端口组件。 容器由薄膜折叠形成以限定相对的侧壁，其被密封以限定用于无菌流体的室。 中空的管状端口构件设置有V形鞍座并且密封到容器的底部。 容器底部的胶片被接收在鞍座中。 独特的肩部由管状端口构件限定。 胶片被密封到肩部和端口构件的鞍座上。 中空穿透元件可滑动地设置在端口构件内并且可在缩回位置和前进位置之间移动以刺穿膜，由此流体可以流出容器。 提供内部结构以引导和限制穿透元件的运动。 容器膜可以沿着容器的底部设置有折痕。
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公开(公告)号：US5611458A
公开(公告)日：1997-03-18
申请号：US435357
申请日：1995-05-05
CPC分类号： A61M5/16809 , G01F11/086
摘要： A method and apparatus are provided for controlling the dispensing of a primary liquid from a pressurized source of primary liquid. Primary liquid is admitted through an inlet valve to a primary chamber having a primary element which is biased toward an initial position but is movable away from the initial position when subjected to the source pressure of the primary liquid. A sensor determines when the primary element has moved away from an initial position to a predetermined final position, and the inlet valve is closed in response thereto. The difference between the initial and final positions defines a predetermined dispensing volume. An outlet valve is opened to dispense the dispensing volume under the biasing force of the primary element which returns to the initial position. A sensor determines when the primary element has returned to the initial position, and the outlet valve is closed in response thereto.
摘要翻译： 提供了一种用于控制从主要液体的加压源分配初级液体的方法和装置。 初级液体通过入口阀进入主腔室，该主腔室具有朝向初始位置偏压的主要元件，但是当经受初级液体的源压力时可移动离开初始位置。 传感器确定主元件何时已经从初始位置移动到预定的最终位置，并且入口阀响应于此而关闭。 初始位置和最终位置之间的差异限定了预定的分配体积。 打开出口阀，以在初始位置的初级元件的偏置力下分配分配容积。 传感器确定主元件何时返回到初始位置，并且出口阀响应于此而关闭。
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公开(公告)号：US5378126A
公开(公告)日：1995-01-03
申请号：US254446
申请日：1994-06-06
申请人： Kent D. Abrahamson , John E. Ogden
发明人： Kent D. Abrahamson , John E. Ogden
CPC分类号： A61M39/04 , A61M5/14224 , A61M2205/12
摘要： A solution pumping system including a disposable pump cassette is disclosed, with the system configured for efficient and accurate preparation of parenteral admixture solutions. The system includes a pump driver having a reciprocable pump plunger and a plurality of associated valve actuators. The disposable pump cassette of the system is configured for removable positioning in operative association with the pump driver, and includes a positive displacement pump configured for operation by the reciprocable pump plunger. The pump cassette further includes a plurality of liquid inlets, and at least one liquid outlet joined in fluid communication with the inlets. By selective operation of the valve actuators of the pump driver, one or more selected source solutions are drawn through the pump inlets by the positive displacement pump, and directed through the pump outlet to an admixture solution container.
摘要翻译： 公开了一种包括一次性泵盒的溶液泵送系统，其中该系统被配置为有效和准确地制备肠胃外混合物溶液。 该系统包括具有往复式泵柱塞和多个相关联的阀致动器的泵驱动器。 系统的一次性泵盒被构造成与泵驱动器可操作地关联的可移动定位，并且包括构造成由往复泵柱塞操作的容积式泵。 泵盒还包括多个液体入口，以及与入口流体连通的至少一个液体出口。 通过泵驱动器的阀致动器的选择性操作，通过正排量泵将一个或多个选定的源解决方案通过泵入口抽吸，并通过泵出口引导到混合溶液容器。
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公开(公告)号：US5098262A
公开(公告)日：1992-03-24
申请号：US635906
申请日：1990-12-28
CPC分类号： F04B43/02 , A61M5/14224 , F04B7/0076
摘要： A solution pumping system includes a compressible pump cassette having front and rear body members, and an elastomeric diaphragm positioned therebetween. The front and rear body members are joined to each other for limited, relative movement, which movement effects compression of the diaphragm. The pump cassette is removably positionable in a pump driver of the system, which can be configured to effect compression of the cassette for use. In this way, the desired compression of the diaphragm during use can be achieved, while avoiding problems associated with compression set or load decay during storage of the cassette prior to use.
摘要翻译： 溶液泵送系统包括具有前和后主体构件的可压缩泵盒，以及设置在其间的弹性膜。 前身体部件和后主体部件彼此接合以进行有限的相对运动，该运动实现隔膜的压缩。 泵盒可移除地定位在系统的泵驱动器中，其可以被配置为实现盒的使用压缩。 以这种方式，可以在使用期间实现膜片期望的压缩，同时避免与使用期间的盒子的储存期间的压缩变形或负载衰减相关的问题。
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5.发明授权公开(公告)号：US08313308B2
公开(公告)日：2012-11-20
申请号：US10810123
申请日：2004-03-26
申请人： Michael W. Lawless , Marwan A. Fathallah , Mansour A. Saleki , Brian A. Kidd , Kent D. Abrahamson , Robert P. Cousineau , Robert R. Boyd , Howard L. Greene
发明人： Michael W. Lawless , Marwan A. Fathallah , Mansour A. Saleki , Brian A. Kidd , Kent D. Abrahamson , Robert P. Cousineau , Robert R. Boyd , Howard L. Greene
CPC分类号： A61M5/14224 , A61M5/16809 , A61M5/16854 , A61M5/172 , A61M2205/128 , A61M2205/3331
摘要： A medical pump with a closed loop stroke feedback system and method, for use with a pumping chamber, for example in a cassette, is disclosed. The pump includes a pumping element that intermittently pressurizes a pumping chamber during a pumping cycle. A pressure sensor detects the pressure exerted by the pumping element on the pumping chamber. A position sensor detects the position of the pumping element. A processing unit processes pressure data from the pressure sensor and position data from the position sensor to determine a calculated stroke volume of the pump for a pump cycle, and to adjust a stroke frequency of the pump to compensate for variation in the stroke volume.
摘要翻译： 公开了一种具有闭环行程反馈系统和方法的医用泵，其用于例如在盒中的泵送室。 泵包括泵送元件，其在泵送循环期间间歇地加压泵送室。 压力传感器检测泵送元件在泵送室上施加的压力。 位置传感器检测泵送元件的位置。 处理单元处理来自压力传感器的压力数据和来自位置传感器的位置数据，以确定用于泵循环的泵的计算行程量，并且调节泵的行程频率以补偿行程体积的变化。
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公开(公告)号：US07905710B2
公开(公告)日：2011-03-15
申请号：US11510106
申请日：2006-08-25
申请人： David T. Wang , Peter J. Scaramuzzi , Mansour A. Saleki , Robert P. Cousineau , Kent D. Abrahamson , Michael W. Lawless , Marwan A. Fathallah , Brian A. Kidd , Robert R. Boyd , Howard L. Greene , Eric R. Navin , Lori E. Lucke , Benjamin T. Mullin
发明人： David T. Wang , Peter J. Scaramuzzi , Mansour A. Saleki , Robert P. Cousineau , Kent D. Abrahamson , Michael W. Lawless , Marwan A. Fathallah , Brian A. Kidd , Robert R. Boyd , Howard L. Greene , Eric R. Navin , Lori E. Lucke , Benjamin T. Mullin
CPC分类号： A61M5/14224 , A61M5/16809 , A61M5/16854 , A61M5/172 , A61M2205/128 , A61M2205/3331
摘要： A medical pump with an improved continuity low flow delivery system and method for use with a pumping chamber, for example in a cassette, is disclosed. The pump includes a pump drive for exerting a force on the pumping chamber and a sensor for sensing the force/pressure exerted by the pump drive on the pumping chamber. The pump drive position sensor senses the position of the pump drive. The medical pump also includes a processing unit and a memory having a programming code adapted to calculate the rate of change of the sensed force/pressure values and determine whether the rate of change of the sensed force/pressure values meets a rate of change threshold. Once the rate of change threshold is met, the programming code is adapted to calculate a remaining pump drive travel value for determining how much farther the pump drive should travel before the end of an effective pump cycle. The programming code is further adapted to trigger one or more signals to drive the pump drive for the remainder of the effective pump cycle using the remaining pump drive travel value.
摘要翻译： 公开了一种具有改进的连续性低流量输送系统的医疗泵以及用于例如在盒中的泵送室的方法。 泵包括用于在泵送室上施加力的泵驱动器和用于感测泵驱动器在泵送室上施加的力/压力的传感器。 泵驱动位置传感器检测泵驱动器的位置。 医疗泵还包括处理单元和具有适于计算检测到的力/压力值的变化率的编程代码的存储器，并且确定检测到的力/压力值的变化率是否满足变化率阈值。 一旦满足了变化率阈值，编程代码就适用于计算剩余的泵驱动行程值，用于确定泵驱动器在有效泵循环结束之前要行进的距离。 编程代码还适用于使用剩余的泵驱动行程值来触发一个或多个信号来驱动泵驱动器的剩余有效泵循环。
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公开(公告)号：US5319979A
公开(公告)日：1994-06-14
申请号：US991024
申请日：1992-12-15
申请人： Kent D. Abrahamson
发明人： Kent D. Abrahamson
CPC分类号： A61M5/16854 , G01L9/006
摘要： The present invention relates to a compression load cell used to monitor pressure in a diapragm cassette pumping system. A plunger is axially slidable in a linear bearing and has a first end in contact with the cassette and the second end in contact with the load cell. The force signals have a direct relationship with the pressure in the cassette.
摘要翻译： 技术领域本发明涉及一种用于监测二压泵送系统中的压力的压缩负荷传感器。 柱塞在线性轴承中可轴向滑动并且具有与盒接触的第一端和与称重传感器接触的第二端。 力信号与盒中的压力有直接的关系。
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