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1.发明授权公开(公告)号：US07805200B2
公开(公告)日：2010-09-28
申请号：US10772944
申请日：2004-02-05
IPC分类号： A61N1/372
CPC分类号： A61N1/3787
摘要： A rechargeable implantable medical device with an external recharging coil carried on the medical device proximal face. The recharging coil can be attached to the medical device housing physically, or chemically, or a combination of both physically and chemically. The recharging coil electrically couples through housing electrical feedthroughs to electronics configured to perform a therapy and a rechargeable power source both carried inside the medical device housing. Additionally methods for attaching the external recharging coil to an implantable medical device are disclosed. The rechargeable implantable medical device can be a medical devices such as a neuro stimulators, drug delivery pumps, pacemakers, defibrillators, diagnostic recorders, cochlear implants, and the like.
摘要翻译： 具有携带在医疗装置近端面上的外部再充电线圈的可充电可植入医疗装置。 充电线圈可以物理或化学地附接到医疗装置壳体，或者物理和化学两者的组合。 充电线圈通过外壳电馈通电耦合到被配置为执行治疗的电子设备和可携带在医疗设备外壳内部的可再充电电源。 公开了另外将外部再充电线圈附接到可植入医疗装置的方法。 可充电植入式医疗装置可以是诸如神经刺激器，药物输送泵，起搏器，除颤器，诊断记录器，人工耳蜗等医疗装置。
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2.发明授权Implantable medical device and electrical stimulation device with magnetic shield 有权可植入医疗器械和带有磁屏蔽的电刺激装置公开(公告)号：US07945334B2
公开(公告)日：2011-05-17
申请号：US10998485
申请日：2004-11-29
IPC分类号： A61N1/18
CPC分类号： A61N1/3787
摘要： A rechargeable implantable medical device with a magnetic shield placed on the distal side of a secondary recharging coil to improve charging efficiency is disclosed. The rechargeable implantable medical device can be a wide variety of medical devices such as neuro stimulators, drug delivery pumps, pacemakers, defibrillators, diagnostic recorders, cochlear implants. The implantable medical device has a secondary recharging coil carried over a magnetic shield and coupled to electronics and a rechargable power source carried inside the housing. The electronics are configured to perform a medical therapy. Additionally a method for enhancing electromagnetic coupling during recharging of an implantable medical device is disclosed, and a method for reducing temperature rise during recharging of an implantable medical device is disclosed.
摘要翻译： 公开了一种具有放置在次级再充电线圈的远侧上的磁屏蔽以提高充电效率的可充电可植入医疗装置。 可充电植入式医疗装置可以是各种各样的医疗装置，例如神经刺激器，药物输送泵，起搏器，去纤颤器，诊断记录器，人工耳蜗植入物。 可植入医疗装置具有一个承载在磁屏蔽上的二次再充电线圈，并耦合到电子装置和一个可充电的电源，该充电电源承载在外壳内。 电子设备被配置为执行医疗治疗。 此外，公开了一种用于在可植入医疗装置的再充电期间增强电磁耦合的方法，并且公开了一种用于在可植入医疗装置的再充电期间降低温度升高的方法。
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公开(公告)号：US06850803B1
公开(公告)日：2005-02-01
申请号：US09596402
申请日：2000-06-16
CPC分类号： A61N1/3787
摘要： A rechargeable implantable medical device with a magnetic shield placed on the distal side of a secondary recharging coil to improve recharging efficiency is disclosed. The rechargeable implantable medical device can be a wide variety of medical devices such as neuro stimulators, drug delivery pumps, pacemakers, defibrillators, diagnostic recorders, and cochlear implants. The implantable medical device has a secondary recharging coil carried over a magnetic shield and coupled to electronics and a rechargeable power source carried inside the housing. The electronics are configured to perform a medical therapy. Additionally a method for enhancing electromagnetic coupling during recharging of an implantable medical device is disclosed, and a method for reducing temperature rise during recharging of an implantable medical device is disclosed.
摘要翻译： 公开了一种具有放置在次级再充电线圈的远侧上的磁屏蔽以提高再充电效率的可充电植入式医疗装置。 可充电植入式医疗装置可以是各种各样的医疗装置，例如神经刺激器，药物输送泵，起搏器，去纤颤器，诊断记录器和人工耳蜗。 可植入式医疗装置具有一个承载在磁屏蔽上的二次再充电线圈，并耦合到电子装置和一个承载在壳体内部的可充电电源。 电子设备被配置为执行医疗治疗。 此外，公开了一种用于在可植入医疗装置的再充电期间增强电磁耦合的方法，并且公开了一种用于在可植入医疗装置的再充电期间降低温度升高的方法。
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公开(公告)号：US08170681B2
公开(公告)日：2012-05-01
申请号：US10998486
申请日：2004-11-29
IPC分类号： A61N1/40
CPC分类号： A61N1/3787
摘要： A rechargeable implantable medical device with a magnetic shield placed on the distal side of a secondary recharging coil to improve charging efficiency is disclosed. The rechargeable implantable medical device can be a wide variety of medical devices such as neuro stimulators, drug delivery pumps, pacemakers, defibrillators, diagnostic recorders, cochlear implants. The implantable medical device has a secondary recharging coil carried over a magnetic shield and coupled to electronics and a rechargeable power source carried inside the housing. The electronics are configured to perform a medical therapy. Additionally a method for enhancing electromagnetic coupling during recharging of an implantable medical device is disclosed, and a method for reducing temperature rise during recharging of an implantable medical device is disclosed.
摘要翻译： 公开了一种具有放置在次级再充电线圈的远侧上的磁屏蔽以提高充电效率的可充电可植入医疗装置。 可充电植入式医疗装置可以是各种各样的医疗装置，例如神经刺激器，药物输送泵，起搏器，去纤颤器，诊断记录器，人工耳蜗植入物。 可植入式医疗装置具有一个承载在磁屏蔽上的二次再充电线圈，并耦合到电子装置和一个承载在壳体内部的可充电电源。 电子设备被配置为执行医疗治疗。 此外，公开了一种用于在可植入医疗装置的再充电期间增强电磁耦合的方法，并且公开了一种用于在可植入医疗装置的再充电期间降低温度升高的方法。
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公开(公告)号：US08366699B2
公开(公告)日：2013-02-05
申请号：US13046687
申请日：2011-03-11
申请人： Oscar Jimenez , Roberto Echarri , Kenneth Verduin
发明人： Oscar Jimenez , Roberto Echarri , Kenneth Verduin
IPC分类号： A61M25/00
CPC分类号： A61M25/0053 , A61M25/0012 , A61M25/005 , A61M25/0054 , A61M25/0108 , B29C47/0004 , B29C47/0016 , B29C47/021 , B29C47/1054 , B29K2105/0005 , B29L2031/7542
摘要： The intravascular catheter has two segments; a proximal segment with high stiffness and a distal segment with lower stiffness. The catheter can also have an intermediate segment of lower stiffness than the proximal segment and higher stiffness than the distal segment. The catheter comprises a polymeric inner tube, a reinforcing inner jacket which is spirally wound over the inner tube and which becomes progressively softer from a proximal end to a distal end, and a polymeric outer sheath extruded over the inner jacket according to the teachings of U.S. Pat. No. 5,445,624. The reinforcing jacket comprises helical coiled wires or fibers of various materials and layers wound over the inner tube in order to provide improved multi-axial mechanical properties, such as torque, compression, tension and anti-kinking characteristics. Stainless steel, carbon, glass, platinum, platinum/tungsten or palladium wire in either oval, round or flat geometry are used together with single or dual layers to achieve a graduated stiffness with the reinforcing jacket being stiffer at a proximal end and softer at a distal end. Methods for making the catheter and for annealing ends of the wound wire are also disclosed.
摘要翻译： 血管内导管有两段; 具有高刚度的近端段和具有较低刚度的远端段。 导管还可以具有比近端段更低刚度的中间段，并且具有比远端段更高的刚度。 导管包括聚合物内管，加强内护套，其螺旋地缠绕在内管上并且从近端到远端逐渐变软，以及根据US的教导在内护套上挤出的聚合物外护套 拍。 第5,445,624号。 加强护套包括螺旋线圈线或各种材料的纤维和缠绕在内管上的层，以提供改进的多轴力学性能，例如扭矩，压缩，张力和抗扭结特性。 椭圆形，圆形或平面几何形状的不锈钢，碳，玻璃，铂，铂/钨或钯线与单层或双层一起使用，以实现渐变刚度，增强护套在近端较硬， 远端。 还公开了用于制造导管和用于退火绕线的端部的方法。
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6.再颁专利RF coupled, implantable medical device with rechargeable back-up power source 有权射频耦合，可植入医疗设备与可充电的备用电源公开(公告)号：USRE42682E1
公开(公告)日：2011-09-06
申请号：US09541351
申请日：2000-03-31
IPC分类号： A61N1/08
CPC分类号： A61N1/08 , A61N1/3787 , Y10S128/903
摘要： The implantable, electrically operated medical device system comprises an implanted radio frequency (RF) receiving unit (receiver) incorporating a back-up rechargeable power supply and an implanted, electrically operated device, and an external RF transmitting unit (transmitter). RF energy is transmitted by the transmitter and is coupled into the receiver which is used to power the implanted medical device and/or recharge the back-up power supply. The back-up power supply within the receiver has enough capacity to be able to, by itself, power the implanted device coupled to the receiver for at least 24 hours during continual delivery of medical therapy. The receiver is surgically implanted within the patient and the transmitter is worn externally by the patient. The transmitter can be powered by either a rechargeable or non-rechargeable battery. In a first mode of operation, the transmitter will supply power, via RF coupled energy, to operate the receiver and simultaneously recharge the back-up power supply. In a second mode of operation, the receiver can, automatically or upon external command from the transmitter, acquire its supply of power exclusively from the back-up power supply. Yet, in a third mode of operation, the receiver can, automatically or upon command from the transmitter, alternatively acquire its supply of power from either, RF energy coupled into the receiver or the internal back-up power supply.
摘要翻译： 可植入的电操作的医疗装置系统包括结合备用可再充电电源和植入的电操作装置的植入式射频（RF）接收单元（接收器）和外部RF发射单元（发射机）。 RF能量由发射器传输并耦合到接收器中，该接收器用于为植入的医疗设备供电和/或对备用电源进行再充电。 接收机内的备用电源具有足够的能力，能够在连续递送医疗治疗期间将连接到接收器的植入装置本身提供至少24小时。 接收器通过外科手术植入患者体内，并且发生器由患者外部佩戴。 变送器可以由可充电电池或不可充电电池供电。 在第一种操作模式下，发射机将通过RF耦合能量供电，以操作接收机并同时对备用电源充电。 在第二种操作模式中，接收器可以自动或根据来自发射器的外部命令从备用电源中独占地获得电力供应。 然而，在第三种操作模式中，接收机可以根据来自发射机的命令自动地或者根据来自发射器的命令，从耦合到接收器中的RF能量或内部备用电源中的RF能量替代地获得电力供应。
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公开(公告)号：US07419633B1
公开(公告)日：2008-09-02
申请号：US11327060
申请日：2006-01-06
申请人： Oscar Jimenez
发明人： Oscar Jimenez
IPC分类号： B29D22/00
CPC分类号： A61L29/12 , A61F2/958 , A61L29/126 , A61L2400/12 , A61M25/10 , B82Y30/00 , C08K7/24 , C08K2201/011 , Y10T156/1038 , Y10T428/1314 , Y10T428/1334 , Y10T428/1352 , Y10T428/1372 , Y10T428/139 , Y10T428/30
摘要： The balloon catheter comprises a plastic tubing, a balloon fused to one end portion of said tubing, and the balloon being made of a polymer and on of a carbon nano-tube material, a nano-clay material or a nano-ceramic fiber material.
摘要翻译： 球囊导管包括塑料管，与所述管的一个端部熔合的气囊，气囊由聚合物和碳纳米管材料，纳米粘土材料或纳米陶瓷纤维材料制成。
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公开(公告)号：US20080103444A1
公开(公告)日：2008-05-01
申请号：US11968610
申请日：2008-01-02
申请人： Oscar Jimenez
发明人： Oscar Jimenez
CPC分类号： A61L29/12 , A61F2/958 , A61L29/126 , A61L2400/12 , A61M25/10 , B82Y30/00 , C08K7/24 , C08K2201/011 , Y10T156/1038 , Y10T428/1314 , Y10T428/1334 , Y10T428/1352 , Y10T428/1372 , Y10T428/139 , Y10T428/30
摘要： The method for making a reinforced balloon for a balloon catheter involves blending a polymer with a nano composite to form a composite matrix, extruding a parison from the composite matrix, blow molding the parison into a balloon and orienting the nano composite generally axially with respect to the balloon. The balloon formed has a high strength for resisting bursting. The nano composite may be carbon nanotubes, nano-ceramic fibers or a nano clay.
摘要翻译： 用于制造用于球囊导管的增强球囊的方法包括将聚合物与纳米复合材料混合以形成复合基质，从复合基质挤出型坯，将型坯吹塑成球，并将纳米复合材料大致轴向相对于 气球。 形成的气球具有很高的抗冲击强度。 纳米复合材料可以是碳纳米管，纳米陶瓷纤维或纳米粘土。
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公开(公告)号：US06278258B1
公开(公告)日：2001-08-21
申请号：US09649918
申请日：2000-08-30
IPC分类号： H01M1046
CPC分类号： A61N1/3708 , A61N1/3787 , H02J7/0031 , H02J7/0063 , H02J7/025 , H02J17/00 , H02J50/20 , H02J50/90
摘要： The method and system for managing power supplied from a charging circuit to a power source in an implantable medical device comprises the steps of and circuitry for: measuring the current drain of the medical device; measuring the elapsed time since the last full charge of a power source of the device; calculating the actual capacity of the power source (corrected for fade) based on the variable of current drain and the variable of elapsed time; calculating the operating time based on the variable of current drain and the variable of the actual capacity of the power source; measuring the voltage of the power source; signaling the medical device when the power source voltage has reached a certain low value which requires disconnection from the power source; disconnecting, during discharging, the power source from the medical device upon the power source reaching a certain low voltage in order to prevent deep discharging of the power source and subsequent damage; precisely limiting the charging voltage to the power source in order to prevent overcharging beyond safe limits; disconnecting, during charging, the power source from the charging circuit upon the power source reaching a certain high voltage in order to prevent overcharging of the power source and subsequent damage; sensing when the electromagnetic waves being transmitted by an RF transmitter/charger induce a voltage level above a certain value at an RF receiver of the implanted power management system; reconnecting power supply inputs of the medical device to the power source upon sensing this induced high voltage level; monitoring the temperature of the power source during charging and discharging; disconnecting the charging circuitry from the power source if the temperature of the power source raises above a certain level during charging; reconnecting the charging circuitry to the power source when the temperature of the power source drops below a certain low value during charging; disconnecting the implanted medical device from the power source if the temperature of the power source raises above a certain level during discharging; and, reconnecting the medical device to the power source when the temperature of the power source drops below a certain low value during discharging.
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公开(公告)号：US5318596A
公开(公告)日：1994-06-07
申请号：US791423
申请日：1991-11-13
IPC分类号： A61N1/365
CPC分类号： A61N1/36542
摘要： The activity sensing pacemaker comprises: a heart pulse sensing device for sensing heart pulses; pulse generating circuitry for generating pacing pulses; activity sensing structure and circuitry for sensing activity/movement of a patient wearing the pacemaker in one or more of three directions/dimensions, x, y, z, and for causing the pulse generating circuitry to generate pacing pulses at a rate/frequency related to the movements sensed; and, control circuitry coupled to the heart pulse sensing device, to the pulse generating circuitry and to the activity sensing structure and circuitry for controlling the pulse generating circuitry in response to the heart pulses sensed or in response to the patient movements sensed, the activity sensing structure and circuitry causing generation of control pulses related to the movements of the patient and the control circuitry including frequency sensing circuitry for sensing the frequency of the control pulses generated and for controlling the rate/frequency of the pacing pulses generated by the pulse generating circuitry relative to the frequency of the control pulses generated by the movements of the patient in one or more directions/dimensions, x, y, z, independent of the duration or amplitude of the control pulses.
摘要翻译： 活动感测起搏器包括：用于感测心脏脉搏的心脏脉搏感测装置; 产生起搏脉冲的脉冲发生电路; 活动感测结构和用于感测佩戴起搏器的患者在三个方向/尺寸x，y，z中的一个或多个中的活动/运动的电路，并且用于使脉冲发生电路以与/ 感觉到运动; 以及耦合到心脏脉冲感测装置的控制电路到脉冲发生电路以及响应于感测到的心脏脉冲或响应于感测到的患者运动而控制脉冲发生电路的活动感测结构和电路，活动感测 导致产生与患者和控制电路的移动相关的控制脉冲的结构和电路，包括用于感测产生的控制脉冲的频率的频率感测电路，并且用于控制由脉冲发生电路相对产生的起搏脉冲的速率/频率 与由控制脉冲的持续时间或振幅无关的一个或多个方向/维度x，y，z中由患者的运动产生的控制脉冲的频率。
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