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    Activity sensing pacemaker
    1.
    发明授权
    Activity sensing pacemaker 失效
    活动感应起搏器

    公开(公告)号：US5318596A

    公开(公告)日：1994-06-07

    申请号：US791423

    申请日：1991-11-13

    申请人： Francisco J. Barreras ,  Oscar Jimenez

    发明人： Francisco J. Barreras ,  Oscar Jimenez

    IPC分类号： A61N1/365

    CPC分类号： A61N1/36542

    摘要： The activity sensing pacemaker comprises: a heart pulse sensing device for sensing heart pulses; pulse generating circuitry for generating pacing pulses; activity sensing structure and circuitry for sensing activity/movement of a patient wearing the pacemaker in one or more of three directions/dimensions, x, y, z, and for causing the pulse generating circuitry to generate pacing pulses at a rate/frequency related to the movements sensed; and, control circuitry coupled to the heart pulse sensing device, to the pulse generating circuitry and to the activity sensing structure and circuitry for controlling the pulse generating circuitry in response to the heart pulses sensed or in response to the patient movements sensed, the activity sensing structure and circuitry causing generation of control pulses related to the movements of the patient and the control circuitry including frequency sensing circuitry for sensing the frequency of the control pulses generated and for controlling the rate/frequency of the pacing pulses generated by the pulse generating circuitry relative to the frequency of the control pulses generated by the movements of the patient in one or more directions/dimensions, x, y, z, independent of the duration or amplitude of the control pulses.

    摘要翻译： 活动感测起搏器包括：用于感测心脏脉搏的心脏脉搏感测装置; 产生起搏脉冲的脉冲发生电路; 活动感测结构和用于感测佩戴起搏器的患者在三个方向/尺寸x，y，z中的一个或多个中的活动/运动的电路，并且用于使脉冲发生电路以与/ 感觉到运动; 以及耦合到心脏脉冲感测装置的控制电路到脉冲发生电路以及响应于感测到的心脏脉冲或响应于感测到的患者运动而控制脉冲发生电路的活动感测结构和电路，活动感测 导致产生与患者和控制电路的移动相关的控制脉冲的结构和电路，包括用于感测产生的控制脉冲的频率的频率感测电路，并且用于控制由脉冲发生电路相对产生的起搏脉冲的速率/频率 与由控制脉冲的持续时间或振幅无关的一个或多个方向/维度x，y，z中由患者的运动产生的控制脉冲的频率。

    Method and apparatus for controlling and steering an electric field
    2.
    发明授权
    Method and apparatus for controlling and steering an electric field 失效
    用于控制和控制电场的方法和装置

    公开(公告)号：US5895416A

    公开(公告)日：1999-04-20

    申请号：US814917

    申请日：1997-03-12

    申请人： Francisco J. Barreras, Sr. ,  Oscar Jimenez

    发明人： Francisco J. Barreras, Sr. ,  Oscar Jimenez

    IPC分类号： A61N1/05 ,  A61N1/34 ,  A61N1/36 ,  A61N1/08

    CPC分类号： A61N1/0551 ,  A61N1/36071 ,  A61N1/36185

    摘要： The electric field steering assembly is used to control the size and/or location of, and/or steer the position of, an electric field in a living creature. The assembly comprises a pulse generator or stimulator, at least one implanted lead coupled to the stimulator and having, at a distal end thereof, at least three spaced apart electrodes, and electrical circuitry for adjusting the current and/or voltage at each electrode. The electrical circuitry is programmed to: 1) electronically change the size and/or location of an electric field established between the electrodes by independently programming the current flowing through of one or more anode (+) electrode(s) from one or more cathode (-) electrode(s), thereby steering the size and location of the electric field to recruit only target certain tissue and exclude unwanted tissue; and, 2) automatically change the voltage amplitude at each anode in response to changes in electrode impedance in order to maintain a constant anodic current, thereby preserving, for the duration of the therapy, the original electric field found to be effective at implant time.

    摘要翻译： 电场转向组件用于控制活体中电场的大小和/或位置和/或转向位置。 所述组件包括脉冲发生器或激励器，至少一个注入引线，其耦合到所述刺激器并且在其远端处具有至少三个间隔开的电极，以及用于调节每个电极处的电流和/或电压的电路。 电路被编程为：1）通过独立编程从一个或多个阴极（一个或多个）阳极（+）电极流过的电流来电子改变建立在电极之间的电场的尺寸和/或位置（ - ）电极，从而转向电场的大小和位置，仅招募目标某些组织并排除不想要的组织; 并且，2）响应于电极阻抗的变化自动改变每个阳极处的电压幅度，以便保持恒定的阳极电流，从而在治疗期间保留在植入时间发现有效的原始电场。

    Double helix reinforced catheter
    3.
    发明授权
    Double helix reinforced catheter 有权
    双螺旋加强导管

    公开(公告)号：US08366699B2

    公开(公告)日：2013-02-05

    申请号：US13046687

    申请日：2011-03-11

    申请人： Oscar Jimenez ,  Roberto Echarri ,  Kenneth Verduin

    发明人： Oscar Jimenez ,  Roberto Echarri ,  Kenneth Verduin

    IPC分类号： A61M25/00

    CPC分类号： A61M25/0053 ,  A61M25/0012 ,  A61M25/005 ,  A61M25/0054 ,  A61M25/0108 ,  B29C47/0004 ,  B29C47/0016 ,  B29C47/021 ,  B29C47/1054 ,  B29K2105/0005 ,  B29L2031/7542

    摘要： The intravascular catheter has two segments; a proximal segment with high stiffness and a distal segment with lower stiffness. The catheter can also have an intermediate segment of lower stiffness than the proximal segment and higher stiffness than the distal segment. The catheter comprises a polymeric inner tube, a reinforcing inner jacket which is spirally wound over the inner tube and which becomes progressively softer from a proximal end to a distal end, and a polymeric outer sheath extruded over the inner jacket according to the teachings of U.S. Pat. No. 5,445,624. The reinforcing jacket comprises helical coiled wires or fibers of various materials and layers wound over the inner tube in order to provide improved multi-axial mechanical properties, such as torque, compression, tension and anti-kinking characteristics. Stainless steel, carbon, glass, platinum, platinum/tungsten or palladium wire in either oval, round or flat geometry are used together with single or dual layers to achieve a graduated stiffness with the reinforcing jacket being stiffer at a proximal end and softer at a distal end. Methods for making the catheter and for annealing ends of the wound wire are also disclosed.

    摘要翻译： 血管内导管有两段; 具有高刚度的近端段和具有较低刚度的远端段。 导管还可以具有比近端段更低刚度的中间段，并且具有比远端段更高的刚度。 导管包括聚合物内管，加强内护套，其螺旋地缠绕在内管上并且从近端到远端逐渐变软，以及根据US的教导在内护套上挤出的聚合物外护套 拍。 第5,445,624号。 加强护套包括螺旋线圈线或各种材料的纤维和缠绕在内管上的层，以提供改进的多轴力学性能，例如扭矩，压缩，张力和抗扭结特性。 椭圆形，圆形或平面几何形状的不锈钢，碳，玻璃，铂，铂/钨或钯线与单层或双层一起使用，以实现渐变刚度，增强护套在近端较硬， 远端。 还公开了用于制造导管和用于退火绕线的端部的方法。

    RF coupled, implantable medical device with rechargeable back-up power source
    4.
    再颁专利
    RF coupled, implantable medical device with rechargeable back-up power source 有权
    射频耦合，可植入医疗设备与可充电的备用电源

    公开(公告)号：USRE42682E1

    公开(公告)日：2011-09-06

    申请号：US09541351

    申请日：2000-03-31

    申请人： Francisco Jose Barreras, Sr. ,  Oscar Jimenez

    发明人： Francisco Jose Barreras, Sr. ,  Oscar Jimenez

    IPC分类号： A61N1/08

    CPC分类号： A61N1/08 ,  A61N1/3787 ,  Y10S128/903

    摘要： The implantable, electrically operated medical device system comprises an implanted radio frequency (RF) receiving unit (receiver) incorporating a back-up rechargeable power supply and an implanted, electrically operated device, and an external RF transmitting unit (transmitter). RF energy is transmitted by the transmitter and is coupled into the receiver which is used to power the implanted medical device and/or recharge the back-up power supply. The back-up power supply within the receiver has enough capacity to be able to, by itself, power the implanted device coupled to the receiver for at least 24 hours during continual delivery of medical therapy. The receiver is surgically implanted within the patient and the transmitter is worn externally by the patient. The transmitter can be powered by either a rechargeable or non-rechargeable battery. In a first mode of operation, the transmitter will supply power, via RF coupled energy, to operate the receiver and simultaneously recharge the back-up power supply. In a second mode of operation, the receiver can, automatically or upon external command from the transmitter, acquire its supply of power exclusively from the back-up power supply. Yet, in a third mode of operation, the receiver can, automatically or upon command from the transmitter, alternatively acquire its supply of power from either, RF energy coupled into the receiver or the internal back-up power supply.

    摘要翻译： 可植入的电操作的医疗装置系统包括结合备用可再充电电源和植入的电操作装置的植入式射频（RF）接收单元（接收器）和外部RF发射单元（发射机）。 RF能量由发射器传输并耦合到接收器中，该接收器用于为植入的医疗设备供电和/或对备用电源进行再充电。 接收机内的备用电源具有足够的能力，能够在连续递送医疗治疗期间将连接到接收器的植入装置本身提供至少24小时。 接收器通过外科手术植入患者体内，并且发生器由患者外部佩戴。 变送器可以由可充电电池或不可充电电池供电。 在第一种操作模式下，发射机将通过RF耦合能量供电，以操作接收机并同时对备用电源充电。 在第二种操作模式中，接收器可以自动或根据来自发射器的外部命令从备用电源中独占地获得电力供应。 然而，在第三种操作模式中，接收机可以根据来自发射机的命令自动地或者根据来自发射器的命令，从耦合到接收器中的RF能量或内部备用电源中的RF能量替代地获得电力供应。

    Implantable power management system
    7.
    发明授权
    Implantable power management system 失效

    公开(公告)号：US06278258B1

    公开(公告)日：2001-08-21

    申请号：US09649918

    申请日：2000-08-30

    申请人： Guillermo Echarri ,  Roberto Echarri ,  Francisco Jose Barreras, Sr. ,  Oscar Jimenez

    发明人： Guillermo Echarri ,  Roberto Echarri ,  Francisco Jose Barreras, Sr. ,  Oscar Jimenez

    IPC分类号： H01M1046

    CPC分类号： A61N1/3708 ,  A61N1/3787 ,  H02J7/0031 ,  H02J7/0063 ,  H02J7/025 ,  H02J17/00 ,  H02J50/20 ,  H02J50/90

    摘要： The method and system for managing power supplied from a charging circuit to a power source in an implantable medical device comprises the steps of and circuitry for: measuring the current drain of the medical device; measuring the elapsed time since the last full charge of a power source of the device; calculating the actual capacity of the power source (corrected for fade) based on the variable of current drain and the variable of elapsed time; calculating the operating time based on the variable of current drain and the variable of the actual capacity of the power source; measuring the voltage of the power source; signaling the medical device when the power source voltage has reached a certain low value which requires disconnection from the power source; disconnecting, during discharging, the power source from the medical device upon the power source reaching a certain low voltage in order to prevent deep discharging of the power source and subsequent damage; precisely limiting the charging voltage to the power source in order to prevent overcharging beyond safe limits; disconnecting, during charging, the power source from the charging circuit upon the power source reaching a certain high voltage in order to prevent overcharging of the power source and subsequent damage; sensing when the electromagnetic waves being transmitted by an RF transmitter/charger induce a voltage level above a certain value at an RF receiver of the implanted power management system; reconnecting power supply inputs of the medical device to the power source upon sensing this induced high voltage level; monitoring the temperature of the power source during charging and discharging; disconnecting the charging circuitry from the power source if the temperature of the power source raises above a certain level during charging; reconnecting the charging circuitry to the power source when the temperature of the power source drops below a certain low value during charging; disconnecting the implanted medical device from the power source if the temperature of the power source raises above a certain level during discharging; and, reconnecting the medical device to the power source when the temperature of the power source drops below a certain low value during discharging.

    External power source, charger and system for an implantable medical device having thermal characteristics and method therefore
    9.
    发明授权
    External power source, charger and system for an implantable medical device having thermal characteristics and method therefore 有权
    因此，具有热特性和方法的可植入医疗装置的外部电源，充电器和系统

    公开(公告)号：US07225032B2

    公开(公告)日：2007-05-29

    申请号：US10836101

    申请日：2004-04-30

    申请人： Andrew L. Schmeling ,  William C. Phillips ,  David P. Olson ,  Oscar Jimenez

    发明人： Andrew L. Schmeling ,  William C. Phillips ,  David P. Olson ,  Oscar Jimenez

    IPC分类号： A61N1/00

    CPC分类号： A61N1/3787 ,  A61M5/14276

    摘要： External power source, charger, system and method for transcutaneous energy transfer. An implantable medical device has a first housing having operational componentry for providing the therapeutic output. A secondary housing is mechanically coupled to the first housing having a secondary coil operatively coupled to the componentry, the secondary coil capable of receiving energy from the external source. A magnetically shielding material is positioned between the secondary coil and the first housing. An external power source has an external housing. A primary coil carried in the external housing, the primary coil being capable of inductively energizing the secondary coil when the housing is externally placed in proximity of the secondary coil with a first surface of the housing positioned closest to the secondary coil, the first surface of the housing being thermally conductive surface. An energy absorptive material carried within the external housing.

    摘要翻译： 外部电源，充电器，用于经皮能量转移的系统和方法。 可植入医疗装置具有第一壳体，其具有用于提供治疗输出的操作组件。 机械地耦合到第一壳体的次级壳体具有可操作地耦合到组件的次级线圈，次级线圈能够从外部源接收能量。 磁屏蔽材料位于次级线圈和第一壳体之间。 外部电源具有外部外壳。 承载在外壳中的初级线圈，当壳体被外部放置在次级线圈附近时，初级线圈能够感应地激励次级线圈，其中壳体的第一表面最靠近次级线圈，第一表面 壳体是导热表面。 在外壳内承载的能量吸收材料。