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公开(公告)号：US08501213B2
公开(公告)日：2013-08-06
申请号：US13617628
申请日：2012-09-14
IPC分类号： A61F13/00
CPC分类号： A61L31/16 , A61F2/91 , A61F2/958 , A61F2230/0054 , A61F2250/0067 , A61F2310/0097 , A61L29/085 , A61L29/16 , A61L31/10 , A61L2300/606 , A61M25/10 , A61M2025/105
摘要： Disclosed is an interventional device for delivery of therapeutic agents from an angioplasty balloon and from a prosthesis such as an intraluminal stent. The invention also relates to the method of loading the beneficial agents onto the balloon and the device, as well as the method of delivery of the agents from separate surfaces. The invention also relates to an interventional device having a prosthesis surface that is loaded with a first beneficial agent, and a balloon surface loaded with a second beneficial agent. The invention also relates to a method of loading multiple beneficial agents onto the prosthesis surfaces and the balloon surfaces, and to a method of manufacturing an interventional device for the delivery of a first beneficial agent and a second beneficial agent from separate surfaces.
摘要翻译： 公开了用于从血管成形术球囊和诸如腔内支架之类的假体递送治疗剂的介入装置。 本发明还涉及将有益试剂装载到球囊和装置上的方法以及将试剂从分开的表面递送的方法。 本发明还涉及具有装载有第一有益试剂的假体表面的介入装置和装载有第二有益试剂的气囊表面。 本发明还涉及一种将多种有益试剂装载到假体表面和球囊表面上的方法，以及制造用于从单独表面递送第一有益试剂和第二有益试剂的介入装置的方法。
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公开(公告)号：US08431145B2
公开(公告)日：2013-04-30
申请号：US12371422
申请日：2009-02-13
IPC分类号： A61F13/00
CPC分类号： A61L31/16 , A61F2/91 , A61F2/958 , A61F2230/0054 , A61F2250/0067 , A61F2310/0097 , A61L29/085 , A61L29/16 , A61L31/10 , A61L2300/606 , A61M25/10 , A61M2025/105
摘要： Disclosed is an interventional device for delivery of therapeutic agents from an angioplasty balloon and from a prosthesis such as an intraluminal stent. The invention also relates to the method of loading the beneficial agents onto the balloon and the device, as well as the method of delivery of the agents from separate surfaces. The invention also relates to an interventional device having a prosthesis surface that is loaded with a first beneficial agent, and a balloon surface loaded with a second beneficial agent. The invention also relates to a method of loading multiple beneficial agents onto the prosthesis surfaces and the balloon surfaces, and to a method of manufacturing an interventional device for the delivery of a first beneficial agent and a second beneficial agent from separate surfaces.
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公开(公告)号：US20130013048A1
公开(公告)日：2013-01-10
申请号：US13617628
申请日：2012-09-14
CPC分类号： A61L31/16 , A61F2/91 , A61F2/958 , A61F2230/0054 , A61F2250/0067 , A61F2310/0097 , A61L29/085 , A61L29/16 , A61L31/10 , A61L2300/606 , A61M25/10 , A61M2025/105
摘要： Disclosed is an interventional device for delivery of therapeutic agents from an angioplasty balloon and from a prosthesis such as an intraluminal stent. The invention also relates to the method of loading the beneficial agents onto the balloon and the device, as well as the method of delivery of the agents from separate surfaces. The invention also relates to an interventional device having a prosthesis surface that is loaded with a first beneficial agent, and a balloon surface loaded with a second beneficial agent. The invention also relates to a method of loading multiple beneficial agents onto the prosthesis surfaces and the balloon surfaces, and to a method of manufacturing an interventional device for the delivery of a first beneficial agent and a second beneficial agent from separate surfaces.
摘要翻译： 公开了用于从血管成形术球囊和诸如腔内支架之类的假体递送治疗剂的介入装置。 本发明还涉及将有益试剂装载到球囊和装置上的方法以及将试剂从分开的表面递送的方法。 本发明还涉及具有装载有第一有益试剂的假体表面的介入装置和装载有第二有益试剂的气囊表面。 本发明还涉及一种将多种有益试剂装载到假体表面和球囊表面上的方法，以及制造用于从单独表面递送第一有益试剂和第二有益试剂的介入装置的方法。
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公开(公告)号：US08057813B2
公开(公告)日：2011-11-15
申请号：US11084172
申请日：2005-03-18
IPC分类号： A61F13/00
CPC分类号： A61F2/91 , A61F2/86 , A61F2/915 , A61F2/958 , A61F2002/91525 , A61F2002/91533 , A61F2002/91575 , A61F2002/91591 , A61F2250/0067 , A61F2310/0097 , A61K47/6957 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/00
摘要： Disclosed is an interventional device for delivery of therapeutic agents from an angioplasty balloon and from a prosthesis such as an intraluminal stent. The invention also relates to the method of loading the beneficial agents onto the balloon and the device, as well as the method of delivery of the agents from separate surfaces. The invention also relates to an interventional device having a prosthesis surface that is loaded with a first beneficial agent, and a balloon surface loaded with a second beneficial agent. The invention also relates to a method of loading multiple beneficial agents onto the prosthesis surfaces and the balloon surfaces, and to a method of manufacturing an interventional device for the delivery of a first beneficial agent and a second beneficial agent from separate surfaces.
摘要翻译： 公开了用于从血管成形术球囊和诸如腔内支架之类的假体递送治疗剂的介入装置。 本发明还涉及将有益试剂装载到球囊和装置上的方法以及将试剂从分开的表面递送的方法。 本发明还涉及具有装载有第一有益试剂的假体表面的介入装置和装载有第二有益试剂的气囊表面。 本发明还涉及一种将多种有益试剂装载到假体表面和球囊表面上的方法，以及制造用于从单独表面递送第一有益试剂和第二有益试剂的介入装置的方法。
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公开(公告)号：US20100023108A1
公开(公告)日：2010-01-28
申请号：US12371422
申请日：2009-02-13
CPC分类号： A61L31/16 , A61F2/91 , A61F2/958 , A61F2230/0054 , A61F2250/0067 , A61F2310/0097 , A61L29/085 , A61L29/16 , A61L31/10 , A61L2300/606 , A61M25/10 , A61M2025/105
摘要： Disclosed is an interventional device for delivery of therapeutic agents from an angioplasty balloon and from a prosthesis such as an intraluminal stent. The invention also relates to the method of loading the beneficial agents onto the balloon and the device, as well as the method of delivery of the agents from separate surfaces. The invention also relates to an interventional device having a prosthesis surface that is loaded with a first beneficial agent, and a balloon surface loaded with a second beneficial agent. The invention also relates to a method of loading multiple beneficial agents onto the prosthesis surfaces and the balloon surfaces, and to a method of manufacturing an interventional device for the delivery of a first beneficial agent and a second beneficial agent from separate surfaces.
摘要翻译： 公开了用于从血管成形术球囊和诸如腔内支架之类的假体递送治疗剂的介入装置。 本发明还涉及将有益试剂装载到球囊和装置上的方法以及将试剂从分开的表面递送的方法。 本发明还涉及具有装载有第一有益试剂的假体表面的介入装置和装载有第二有益试剂的气囊表面。 本发明还涉及一种将多种有益试剂装载到假体表面和球囊表面上的方法，以及制造用于从单独表面递送第一有益试剂和第二有益试剂的介入装置的方法。
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公开(公告)号：US20180126119A1
公开(公告)日：2018-05-10
申请号：US15662008
申请日：2017-07-27
CPC分类号： A61M25/005 , A61F2/2436 , A61F2/966 , A61F2210/0076 , A61F2230/0091 , A61F2250/0018 , A61F2250/0065 , A61M25/0045 , A61M25/0051 , A61M25/0136 , A61M25/0147 , A61M25/0662 , A61M25/09 , A61M2025/0046 , A61M2025/0063 , A61M2025/0175 , A61M2025/0681
摘要： An intravascular delivery system includes a delivery sheath capable of transmitting a predetermined tension or compression force in a longitudinal direction while maintaining flexibility to navigate tortuous anatomy. A method of delivering a medical device includes inserting an intravascular device delivery system including a delivery sheath having a continuous spine into a bodily lumen. A distal longitudinal force is applied to the delivery sheath. The distal force is transmitted through the continuous spine and across one or more slit cuts of the delivery sheath. A proximal longitudinal force is applied to the delivery sheath. The proximal longitudinal force is transmitted through the continuous spine of the delivery sheath.
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公开(公告)号：US08900286B2
公开(公告)日：2014-12-02
申请号：US13037008
申请日：2011-02-28
CPC分类号： A61F2/0095 , A61F2002/9505 , A61F2002/9583 , A61F2002/9665
摘要： Device shields for packaging and protecting medical devices during storage and deployment. A device shield includes a housing configured to maintain a medical device and at least a portion of a medical device delivery apparatus within the housing, and a limit element having a first constraining position and a second open position.
摘要翻译： 在存储和部署期间用于包装和保护医疗设备的设备屏蔽。 设备屏蔽包括被配置为将医疗设备和医疗设备传送设备的至少一部分保持在壳体内的壳体，以及具有第一约束位置和第二打开位置的限制元件。
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公开(公告)号：US20130006220A1
公开(公告)日：2013-01-03
申请号：US13616305
申请日：2012-09-14
申请人： Travis R. Yribarren , Randolf von Oepen , Kevin J. Ehrenreich , William E. Webler, JR. , Richard R. Newhauser
发明人： Travis R. Yribarren , Randolf von Oepen , Kevin J. Ehrenreich , William E. Webler, JR. , Richard R. Newhauser
IPC分类号： A61M25/10
CPC分类号： A61M25/1006 , A61F2/958 , A61M25/0119 , A61M2025/1015 , A61M2025/105 , A61M2025/1059 , A61M2025/1065 , A61M2025/1068
摘要： The present invention relates to balloon catheters for treating a luminal system of a patient. Specifically, the invention relates to catheters having a flexible membrane positioned at a distal portion of the catheter, the flexible membrane retained in a substantially unexposed conformation prior to deployment. Preferably the flexible membrane is capable of delivering a therapeutic agent to a localized environment when deployed to an exposed conformation.
摘要翻译： 本发明涉及用于治疗患者的管腔系统的气囊导管。 具体地，本发明涉及具有位于导管的远端部分的柔性膜的导管，柔性膜在展开之前保持基本上未曝光的构象。 优选地，当部署到暴露的构象时，柔性膜能够将治疗剂递送至局部环境。
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公开(公告)号：US20120046731A1
公开(公告)日：2012-02-23
申请号：US13087344
申请日：2011-04-14
IPC分类号： A61F2/82
CPC分类号： A61F2/915 , A61F2/2475 , A61F2/88 , A61F2/958 , A61F2002/825 , A61F2002/8483 , A61F2002/91558 , A61F2002/91566 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/0054 , A61F2230/0076 , A61F2230/0078
摘要： Devices and methods for treating veins and venous conditions, such as chronic cerebrospinal venous insufficiency, are provided. In one aspect, the disclosed subject matter provides an intraluminal scaffold having a generally tubular body with a lumen defined therethrough, the tubular body having a compressed condition for delivery and an expanded condition for implant within a vessel having a distended portion, at least a length of the tubular body configured to form an enlarged portion in the expanded condition to engage a wall of the distended portion of the vessel. Methods for fabricating and using the scaffold, methods for remodeling a vein, and methods of deploying a medical device in a vessel without negatively impacting the function of a valve of the vessel, are also provided.
摘要翻译： 提供了用于治疗静脉和静脉疾病如慢性脑脊髓静脉功能不全的装置和方法。 在一个方面，所公开的主题提供了一种管腔内支架，其具有通过其限定的内腔的大体管状体，该管状体具有用于输送的压缩状态和用于植入物的膨胀状态，该容器具有扩张部分，至少长度 所述管体被构造成在膨胀状态下形成扩大部分以接合容器的扩张部分的壁。 还提供了制造和使用支架的方法，用于重建静脉的方法，以及在容器中部署医疗装置的方法，而不会不利地影响容器的阀的功能。
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公开(公告)号：US08109984B2
公开(公告)日：2012-02-07
申请号：US11326546
申请日：2006-01-04
申请人： Jan Otto Solem , Per-Ola Kimblad , Randolf von Oepen , Bodo Quint , Gerd Seibold , Kenneth J. Michlitsch , Suk-Woo Ha , Karl-Ludwig Eckert , Ib Joergensen , Stevan Nielsen
发明人： Jan Otto Solem , Per-Ola Kimblad , Randolf von Oepen , Bodo Quint , Gerd Seibold , Kenneth J. Michlitsch , Suk-Woo Ha , Karl-Ludwig Eckert , Ib Joergensen , Stevan Nielsen
IPC分类号： A61F2/06
CPC分类号： A61F2/2451 , A61F2/07 , A61F2/88 , A61F2/90 , A61F2/91 , A61F2002/826 , A61F2002/828 , A61F2002/8483 , A61F2210/0004
摘要： A device for treatment of mitral annulus dilation is disclosed, wherein the device comprises two states. In a first of these states the device is insertable into the coronary sinus and has a shape of the coronary sinus. When positioned in the coronary sinus, the device is transferable to the second state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus and the radius of curvature as well as the circumference of the mitral annulus is reduced.
摘要翻译： 公开了一种用于治疗二尖瓣环扩张的装置，其中该装置包括两种状态。 在这些状态中的第一个状态下，该装置可插入冠状窦并具有冠状窦的形状。 当定位在冠状窦中时，假设曲率半径减小，装置可转移到第二状态，由此降低冠状窦的曲率半径和曲率半径以及二尖瓣环的圆周。
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