公开(公告)号：US20050098183A1

公开(公告)日：2005-05-12

申请号：US10749513

申请日：2004-01-02

申请人： John Nash ,  Lois Williams ,  Simon Neame ,  Eric Pagan ,  Giles Bishop ,  David Bower ,  Clive Stinton

发明人： John Nash ,  Lois Williams ,  Simon Neame ,  Eric Pagan ,  Giles Bishop ,  David Bower ,  Clive Stinton

IPC分类号： A61J15/00 ,  A61M16/06 ,  A61M16/20 ,  B29C45/16 ,  A62B18/02 ,  A62B18/08

CPC分类号： B29C45/1676 ,  A61J15/0003 ,  A61M16/06 ,  A61M16/0616 ,  A61M16/0683 ,  A61M16/206 ,  A61M16/208 ,  A61M16/209 ,  A61M2202/0225 ,  B29C2791/001 ,  A61M2202/0085

摘要： A face mask has a relatively soft canopy and a more rigid reinforcement member moulded together from different plastics as two shots in a dual-shot moulding process. The peripheral sealing edge of the canopy is tapered to a reduced thickness to increase its flexibility. The reinforcement member is a frame with radially-extending arms supporting respectively a gas port by which gas can enter the mask, a valve that allows air into the mask when there is an inadequate supply at the gas port and a selectively closable vent. The mask is secured to the patient's head by a harness attached to ends of the harness arms.

摘要翻译： 面罩具有相对柔软的冠层和更加刚性的加强构件，其在两次注射成型过程中由两种不同的塑料模制在一起。 顶盖的外围密封边缘逐渐减小，以增加其灵活性。 加强构件是具有径向延伸的臂的框架，其分别支撑气体可以进入掩模的气体端口，当气体端口处的供应不足和可选择关闭的通气口时，允许空气进入掩模的阀。 面罩通过附接到线束臂的端部的线束固定到患者的头部。

公开(公告)号：US20090083328A1

公开(公告)日：2009-03-26

申请号：US12010777

申请日：2008-01-30

申请人： Michele Vivona ,  Donald G. Peterson ,  Jeffrey Pfeifer ,  Kevin Stehr ,  David Dilenschneider ,  John Nash ,  William Hagy ,  Duane Wald ,  Ryan Sanders ,  Travis J. Olson

发明人： Michele Vivona ,  Donald G. Peterson ,  Jeffrey Pfeifer ,  Kevin Stehr ,  David Dilenschneider ,  John Nash ,  William Hagy ,  Duane Wald ,  Ryan Sanders ,  Travis J. Olson

IPC分类号： G06F17/30

CPC分类号： G06Q10/10 ,  G06F16/338 ,  G06Q50/18

摘要： Systems and methods for profiled and focused searching of litigation information allow a user to access specific legal information for use during litigation. The user can connect to a web site and access particular information from multiple sources based on the litigation task the user wishes to accomplish One litigation task is to create a litigation profile for a target, such as a particular litigant, attorney, judge, court, or firm. In this way, the user can perform focused and task-based searching to receive information about particular filings in particular locations, made by particular entities without knowing which sources contain certain pieces of the litigation information. For example, the user can receive all documents relating to summary judgment for patent infringement filed by a particular attorney in a particular court without specifying the source of information. In one aspect, the user can also access the source(s) upon receiving the results.

摘要翻译： 用于分析和集中搜索诉讼信息的系统和方法允许用户访问特定的法律信息以供诉讼期间使用。 用户可以根据用户希望完成的诉讼任务，连接到网站并访问多个来源的特定信息。一个诉讼任务是为目标创建诉讼简档，例如特定诉讼人，律师，法官，法庭， 或公司。 以这种方式，用户可以执行重点突出和基于任务的搜索来接收关于特定地点的特定文件的信息，由特定实体制作，而不知道哪些源包含某些诉讼信息。 例如，用户可以接收与特定律师在特定法院提交的专利侵权的简易判断有关的所有文件，而不指定信息来源。 在一个方面，用户还可以在接收到结果时访问源。

公开(公告)号：US20080097499A1

公开(公告)日：2008-04-24

申请号：US11871908

申请日：2007-10-12

申请人： John Nash ,  Greg Walters ,  Dennis Sauro ,  Mark Eberharot ,  William Fisher ,  Douglas Evans

发明人： John Nash ,  Greg Walters ,  Dennis Sauro ,  Mark Eberharot ,  William Fisher ,  Douglas Evans

IPC分类号： A61B17/22

CPC分类号： A61B17/320758 ,  A61B17/320783 ,  A61B2017/00685 ,  A61B2017/320733 ,  A61B2017/320741 ,  A61B2017/320766 ,  A61B2217/005

摘要： A device suitable for removing material from a living being is provided, featuring at least an aspiration pump, powered by a motor. The aspiration pump and any optional infusate pump preferably feature a helical pumping mechanism, and operate at a high rate of rotation, thereby ensuring adequate pumping performance and flexibility. The helical pumping mechanism may be a helical coiled wire about a central core tube. The helical coil wire, whether together with, or independent of, the core tube, may be rotated to cause a pumping action. Additionally, a narrow crossing profile is maintained, ensuring that the device may reach more tortuous regions of the vasculature. In one embodiment, the system comprises a wire-guided mono-rail catheter with a working head mounted on a flexible portion of the catheter that can laterally displace away from the guide wire to facilitate thrombus removal. The working head may be operated to separate and move away from the guide wire to come within a closer proximity of the obstructive material to more effectively remove it from the vessel.

摘要翻译： 提供一种适用于从活体中去除材料的装置，其特征在于至少一个由马达驱动的抽吸泵。 抽吸泵和任何可选的输注泵优选地具有螺旋泵送机构，并且以高转速进行操作，从而确保了足够的泵送性能和灵活性。 螺旋泵送机构可以是围绕中心芯管的螺旋卷绕的线。 螺旋线圈线，无论是与芯管一起，还是独立于芯管，可以旋转以引起泵送动作。 另外，保持狭窄的横截面，确保装置可能达到脉管系统的更曲折的区域。 在一个实施例中，系统包括导线单轨导管，其具有安装在导管的柔性部分上的工作头，所述工作头能横向移位远离引导线以促进血栓移除。 工作头可以被操作以分离并远离引导线进入更靠近阻塞物质的位置，以更有效地将其从容器中移出。

公开(公告)号：US20080051720A1

公开(公告)日：2008-02-28

申请号：US11928897

申请日：2007-10-30

申请人： John Nash ,  Gregory Walters ,  Douglas Evans ,  David Szabo ,  Michael Paris

发明人： John Nash ,  Gregory Walters ,  Douglas Evans ,  David Szabo ,  Michael Paris

IPC分类号： A61M25/01

CPC分类号： A61M25/0169 ,  A61M25/09041 ,  A61M2025/018 ,  A61M2025/0183

摘要： An attachment tool to facilitate the attachment of one or more catheters or similar elongated instruments to a guide-wire or other elongated guide member, without requiring access to either end of said wire or member. The tool provides repeatable and reliable alignment of components to be attached, while being operated with a single hand. The catheter systems can be used for revascularization or treatment of arteries and lumens within the body, and the associated delivery of therapies therein and can include side attachable and over-the-wire components and/or low profile combination catheters to allow for flush and extraction of debris in small or tortuous anatomic pathways.

摘要翻译： 附件工具，以便于将一个或多个导管或类似的细长器械连接到导丝或其它细长导向件，而不需要接近所述线或构件的任一端。 该工具在单手操作的同时可提供要连接的组件的可重复且可靠的对齐。 导管系统可用于血管重建或治疗体内的动脉和腔，以及其中相关的治疗传递，并且可以包括侧附件和线上组件和/或薄型组合导管，以允许冲洗和提取 的碎屑在小或曲折的解剖通路。

公开(公告)号：US20070293881A1

公开(公告)日：2007-12-20

申请号：US11849206

申请日：2007-08-31

申请人： John Nash ,  Douglas Evans ,  David Hoganson

发明人： John Nash ,  Douglas Evans ,  David Hoganson

IPC分类号： A61B17/11

CPC分类号： A61B17/11 ,  A61B17/0057 ,  A61B17/06 ,  A61B17/12009 ,  A61B2017/00004 ,  A61B2017/00243 ,  A61B2017/1107 ,  A61B2017/1135

摘要： A system and method of use for effecting the bypass or other anastomosis, connection, or port in a portion of a native blood vessel, duct, lumen or other tubular organ within the body of a living being. The system includes a connector assembly and a deployment instrument for carrying the device to the desired position within the vessel, duct, lumen or tubular organ. The system includes a piercer-dilator instrument to form an opening in the wall of the vessel, duct, lumen or tubular organ into which a connector assembly may be deployed by the deployment instrument. The connector assembly may be at least partially formed of a resorbable material and includes movable members for securing it to the tissue of the vessel, duct, lumen or tubular organ contiguous with the opening. Other components may be included in the device for expediting the procedure, with or without the use of sutures.

摘要翻译： 用于在生命体内的天然血管，导管，内腔或其他管状器官的一部分中实现旁路或其它吻合，连接或端口的系统和方法。 该系统包括连接器组件和用于将装置运送到容器，管道，管腔或管状器官内所需位置的展开仪器。 该系统包括穿孔器 - 扩张仪器，以在容器，管道，管腔或管状器官的壁中形成开口，连接器组件可以由展开仪器部署到该开口中。 连接器组件可以至少部分地由可再吸收的材料形成，并且包括用于将其固定到与开口相邻的容器，管道，管腔或管状器官的组织的可移动构件。 在使用或不使用缝合线的情况下，可以在装置中包括用于加速该程序的其它部件。

公开(公告)号：US20050080357A1

公开(公告)日：2005-04-14

申请号：US10928027

申请日：2004-08-28

申请人： Mark Eberhart ,  William Fisher ,  John Nash ,  Dennis Sauro

发明人： Mark Eberhart ,  William Fisher ,  John Nash ,  Dennis Sauro

IPC分类号： A61F2/958 ,  A61B5/00 ,  A61M25/00

CPC分类号： A61M25/10182 ,  A61M25/10185

摘要： An apparatus for modulating the pressure of a fluid such as a gas within the expandable portion of a guide wire catheter. A preferred embodiment apparatus features a mechanism for controllably gripping and releasing the open, proximal end of a tubular guide wire, a mechanism for introducing a fluid to a desired pressure and volume into the expandable portion of the tubular guide wire through the open end, and, while maintaining the pressure and volume of fluid in the tubular guide wire, a mechanism for introducing a sealing member into the chamfered, open end of the tubular guide wire to consistently seal the fluid in the tubular guide wire. In a particularly preferred embodiment, the apparatus also features a deflation tool for piercing the seal and letting the fluid out. Using this apparatus, the tubular guide wire can be re-sealed and re-opened as necessary.

摘要翻译： 一种用于调节导丝导管内的可膨胀部分内的流体例如气体的压力的装置。 优选的实施例装置具有用于可控地夹紧和释放管状导丝的开口近端的机构，用于将流体通过开口端引导到管状导丝的可膨胀部分中的期望压力和体积的机构，以及 同时保持管状导丝中的流体的压力和体积，用于将密封构件引入管状导丝的倒角开口端的机构，以一致地密封管状导丝中的流体。 在特别优选的实施例中，该装置还具有用于刺穿密封件并使流体流出的放气工具。 使用这种装置，可以根据需要重新密封和重新打开管状导丝。

公开(公告)号：US5192302A

公开(公告)日：1993-03-09

申请号：US783645

申请日：1991-10-28

申请人： Kenneth Kensey ,  John Nash

发明人： Kenneth Kensey ,  John Nash

IPC分类号： A61B17/04 ,  A61B17/00 ,  A61B17/12 ,  A61F2/06

CPC分类号： A61B17/0057 ,  A61B2017/00004 ,  A61F2/06

摘要： Closure devices and methods of use for sealing a small, e.g., percutaneous, incisions or punctures. The closure device may take many forms an basically comprises a somewhat elongated plug having a deformable distal end portion including a free end to which a thin retraction filament is connected. The closure device is arranged to be introduced into the body of the being through the incision or puncture by an introducer so that the distal portion of the plug is located on one side of said tissue and its proximal portion is located on the other side of that tissue, with the filament extending through the incision or puncture. The filament is arranged to be grasped and pulled in the proximal direction to deform the distal portion of the plug so that it cannot pass back through the incision or puncture, whereupon the puncture or incision is sealed by the deformed distal portion of the plug. The distal portion of the plug is non-hemostatic so that when the closure is used to seal an incision or puncture in a blood vessel it will not produce any blood clots within the vessel.

摘要翻译： 闭合装置和用于密封小例如经皮切口或穿刺的使用方法。 闭合装置可以采取许多形式，基本上包括稍微细长的插头，其具有可变形的远端部分，该可变形的远端部分包括连接有薄的缩回细丝的自由端。 闭合装置被布置成通过导引器通过切口或穿刺引入到身体中，使得插塞的远端位于所述组织的一侧上，并且其近端部分位于所述组织的另一侧 组织，细丝延伸穿过切口或穿刺。 长丝布置成沿近端方向被抓住并拉动，以使插塞的远端部分变形，使得其不能通过切口或穿刺返回，于是穿孔或切口被插塞的变形的远端部分密封。 插塞的远端部分是非止血的，因此当封闭件用于密封血管中的切口或穿刺时，其不会在血管内产生任何血块。

公开(公告)号：US5002549A

公开(公告)日：1991-03-26

申请号：US322754

申请日：1989-03-13

申请人： John Nash

发明人： John Nash

IPC分类号： A61B17/22

CPC分类号： A61B17/320758

摘要： A method and apparatus for destroying a stone or other hard body located within the body of a living being at a location where the stone is within a liquid. The apparatus comprises a catheter having a rotatable working head at its distal end. The working head comprises at least two radially extending blade-like members, each having plural force concentrating impacting surfaces and plural grooves. The working head is rotated at a high speed while it is in engagement with the stone. The rotation of the working head produces a flow of the liquid past the working head, with some portion of the liquid flowing through the plural grooves. The impacting surfaces impact the stone to break it into particles which are carried by the flow into repeated engagement with the impacting surfaces for further pulverization. The liquid flowing through the grooves reduces the boundary layer effect which tends to sweep smaller particles away from the impacting surfaces. Accordingly, the efficient pulverization of the particles and the destruction of the stone is effected without appreciable injury to the body of the being.

摘要翻译： 一种用于破坏位于石头在液体内的生物体内的石头或其他硬质体的方法和装置。 该装置包括在其远端具有可旋转工作头的导管。 工作头包括至少两个径向延伸的叶片状构件，每个具有多个强力冲击表面和多个凹槽。 工作头在与石头接合时以高速旋转。 工作头的旋转产生液体流过工作头的流动，其中一部分液体流过多个凹槽。 冲击表面撞击石头以将其分解成颗粒，颗粒由流体承载，与冲击表面重复接合，以进一步粉碎。 流过槽的液体减少了边界层效应，其倾向于将较小的颗粒从冲击表面扫除。 因此，对颗粒的有效粉碎和石头的破坏实现，而对身体的身体没有明显的伤害。

公开(公告)号：US4749376A

公开(公告)日：1988-06-07

申请号：US922978

申请日：1986-10-24

申请人： Kenneth Kensey ,  John Nash

发明人： Kenneth Kensey ,  John Nash

IPC分类号： A61B17/22 ,  A61B17/00

CPC分类号： A61B17/320758

摘要： A catheter device for introduction into the body of a being to effect a procedure, e.g., lumen opening, therein. The catheter is an elongated member having a working head at its distal end and is sufficiently flexible and of small diameter to enable it to be located within the body of the being with the working head at the situs of the procedure. The catheter comprises an elongated drive wire extending through the catheter and motion transtator located at the distal end of the catheter. The wire is rotated at a high speed and the transtator translate that rotary motion into high speed reciprocation of the working head. In some embodiments, the motion transtator also causes the working head to be rotated at the same time it is reciprocated. In other embodiments, the working head is only reciprocated. In all cases, the motion of the working head is at a very high speed. The catheter also includes means to provide a fluid therethrough so that when the catheter is used to open a lumen, e.g., an arterial restriction caused by atherosclerotic plaque, the rotation of the working head causes the fluid to impact the artery wall.

摘要翻译： 导管装置，其用于引入体内以进行例如内腔开放的过程。 导管是细长构件，其在其远端具有工作头，并且具有足够的柔性并且具有小的直径，以使得其能够位于与工作头的身体内的位置处的位置处。 导管包括延伸穿过导管的细长驱动线和位于导管远端的运动转运器。 电线以高速旋转，并且转换器将旋转运动转换为工作头的高速往复运动。 在一些实施例中，运动转移器还使得工作头在其往复运动的同时旋转。 在其他实施例中，工作头仅往复运动。 在所有情况下，工作头的运动速度非常快。 导管还包括通过其提供流体的装置，使得当导管用于打开内腔，例如由动脉粥样硬化斑块引起的动脉阻塞时，工作头的旋转导致流体冲击动脉壁。

公开(公告)号：US4747821A

公开(公告)日：1988-05-31

申请号：US921973

申请日：1986-10-22

申请人： Kenneth Kensey ,  John Nash

发明人： Kenneth Kensey ,  John Nash

IPC分类号： A61B17/22 ,  A61B17/32 ,  A61B17/00

CPC分类号： A61B17/320758 ,  A61B2017/22097 ,  A61B2017/320044

摘要： A flexible, small diameter catheter for effecting various surgical procedures, such as opening a restriction formed of an undesirable material, e.g., atherosclerotic plaque, in a lumen, e.g., an artery, of a living being. The catheter includes a working head having at least one, non-sharp impacting surface arranged to be moved, e.g., rotated, at a high rate of speed by an associated drive means within the catheter. The catheter with the moving working head is brought into engagement to effect the opening of the restriction by dilating the artery and/or removing undesirable material therefrom. The removal of undesirable material results from the impacting surface impacting the material of the restriction repeatedly. A fluid is provided through the catheter to the working head and a portion is thrown radially outward. The fluid at the working head also flows in a vortex to cause any particles broken off from the restriction back to the moving working head where they are impacted again and again to further reduce their size. Such action creates particles of sufficiently small size that they may be enabled to flow distally without significant deleterious effects to distally located tissue.

摘要翻译： 用于实现各种外科手术的柔性小直径导管，例如在活体的内腔（例如动脉）中打开由不期望的材料形成的限制，例如动脉粥样硬化斑块。 导管包括具有至少一个非锐利的冲击表面的工作头，所述至少一个非锋利的冲击表面布置成通过导管内的相关联的驱动装置以高速率移动，例如旋转。 具有移动的工作头的导管被接合以通过扩张动脉和/或从其中去除不需要的材料来实现限制的打开。 不希望的材料的去除会从冲击表面反复冲击限制材料。 流体通过导管提供到工作头部，并且一部分被径向向外抛出。 工作头处的流体也会在涡流中流动，使任何颗粒从限制器中分离回到移动的工作头部，在那里它们被一次又一次的冲击，以进一步减小其尺寸。 这样的作用产生足够小尺寸的颗粒，使得它们能够向远端流动，而对远端定位的组织没有显着的有害作用。