摘要:
A method for stimulating prosaposin receptor activity in a cell by transfecting the cell with a DNA or RNA molecule encoding prosaposin or a prosaposin receptor agonist. The DNA or RNA molecule is administered either in vivo or used to transfect neural cells or neural stem cells ex vivo followed by reintroduction of the cells into an individual.
摘要:
The book trimming apparatus includes guides which direct a collated and, optionally, bound book to a fore-edge trimming station. The book trimming apparatus further includes a transfer station and a side-edge trimming station. For both the fore-edge trimming station and the side-edge trimming station in each case the book is orientated so that the edge to be trimmed is arranged substantially parallel to the direction of motion of the book. The automated book trimming apparatus is particularly suited for use in combination with collation and binding stations in in-line book manufacture.
摘要:
A device and method for deploying a mechanical closure device for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart. The single disc mechanical closure device is comprise of a distal and proximal anchor constrained by a closure line to facilitate mechanical closure by bringing the distal and proximal anchors into close proximity along the closure line.
摘要:
A method and system for limiting energy to a sensor and/or an environment in which the sensor is located. A high current sensor driver is powered through a resistance-capacitance (RC) circuit. In a failure mode, the RC circuit constrains output of a sensor driver to the sensor in order to limit average current applied to the sensor. In one embodiment, the capacitor is chosen so that it can provide adequate current to the sensor driver for a short period of time. The value of the resistor may be chosen to ensure that under short circuit conditions direct current (DC) is limited to a safe value. The combined values of the resistor and capacitor may be adjusted such that the capacitor can charge to a prescribed level during the interval between active pulses.
摘要:
A tire in which a tire manufacturer has determined the tractive capacity at numerous levels of tread wear, the tire having at least one visual warning indicator located at a tread depth corresponding to a percentage loss of tractive capacity. Also, a method of making the tire and a method improving traffic safety through use of such a tire combined with educating the consumer as to proper use of the tire.
摘要:
Binding apparatus and a related process are particularly suited for binding digitally-printed sheets into booklets. The apparatus is adapted to fold individual sheets and then to apply adhesive to the fold line before gathering the sheets in a collator ready for binding. The collator includes either a rotatable or retractable finger that is moveable to temporarily inhibit registration of a first sheet of a new stack on a stacking area, as a previous stack is transported away.
摘要:
This invention comprises a method for defining, establishing and operating a business model, or an augmentation to a business model, that uses a grant of a portion of the equity of a startup company as a component in a deal with a professional service company such as a consulting company. The present invention includes the grant of a portion of the equity in a startup company that serves at least three unique, simultaneous purposes: (1) as inducement to the professional services company to participate in assisting or otherwise supporting the startup; (2) as a cost free component to the professional services company, a portion of which (for example, 50%), is then allocated as a payment budget to the various employee's or agents of the professional services company if and only if they perform work for the startup company; this allocation of stock interest to the individual employee or agent, is in a parallel payment fashion and represents a new and independent way of compensation for those company employees and hence does not factor into any of their current compensation schemes; and (3) once earned and allocated for a particular professional services company employee, this stock then becomes a further inducement to retain the professional services company employee, as they would, in most instances, forfeit their various stock interests of this type if they resign their employment.
摘要:
Combinatorially generated peptides are provided that have binding affinity for polyethylene (PE). The peptides may be used to deliver benefit agents to various PE surfaces.