Reversing, postponing or preventing the occurrence of GTN tolerance and/or generation of reactive oxygen species from mitochondria
    1.
    发明申请
    Reversing, postponing or preventing the occurrence of GTN tolerance and/or generation of reactive oxygen species from mitochondria 失效
    逆转,推迟或预防GTN耐受和/或从线粒体产生活性氧的发生

    公开(公告)号:US20050148612A1

    公开(公告)日:2005-07-07

    申请号:US10980801

    申请日:2004-11-04

    CPC分类号: A61K31/41 A61K31/04 A61K31/52

    摘要: A patient in need of nitroglycerin therapy is treated with nitroglycerin and agent that prevents inhibition of or reverses inhibition of mtALDH and/or the generation of reactive oxygen species from mitochondria, e.g., a mitochondrial antioxidant which is not a reducing agent or a dithiol, e.g., ebselen or uric acid. Nitroglycerin dosage can be regulated and inhibiting agent dosage can be regulated and tolerance postponed by monitoring blood level of active mtALDH and dosing in response to determined level of active mtALDH.

    摘要翻译: 需要硝酸甘油治疗的患者用硝酸甘油和药剂治疗,其防止抑制或逆转mtALDH的抑制和/或从线粒体产生活性氧,例如不是还原剂或二硫醇的线粒体抗氧化剂,例如 ,依勃硒或尿酸。 通过监测活性mtALDH的血液水平和给药以响应确定的活性mtALDH水平,可以调节硝酸甘油剂量并且可以调节抑制剂剂量并进行耐受性推迟。

    Methods and composition based on discovery of metabolism of nitroglycerin
    2.
    发明申请
    Methods and composition based on discovery of metabolism of nitroglycerin 失效
    基于硝酸甘油代谢发现的方法和组成

    公开(公告)号:US20050131063A1

    公开(公告)日:2005-06-16

    申请号:US10508957

    申请日:2003-02-24

    IPC分类号: A61K31/21 A61K45/06

    摘要: Therapies are for treating patients in need of nitroglycerin therapy and allow increased dosage, postponement of tolerance and preconditioning, without exacerbating or causing hypotension. Methods for determining cross-tolerance, nitroglycerin effectiveness and dose are also disclosed. Composition for intravenous administration of nitroglycerin does not contain ethanol or contains less ethanol than conventional compositions.

    摘要翻译: 疗法用于治疗需要硝酸甘油治疗的患者,并允许增加剂量,推迟耐受性和预处理,而不会加重或引起低血压。 还公开了用于确定交叉耐受性,硝酸甘油有效性和剂量的方法。 用于静脉内施用硝酸甘油的组合物不含乙醇或含有比常规组合物少的乙醇。

    Reversing, postponing or preventing the occurrence of GTN tolerance and/or generation of reactive oxygen species from mitochondria
    3.
    发明授权
    Reversing, postponing or preventing the occurrence of GTN tolerance and/or generation of reactive oxygen species from mitochondria 失效
    逆转,推迟或预防GTN耐受和/或从线粒体产生活性氧的发生

    公开(公告)号:US07776925B2

    公开(公告)日:2010-08-17

    申请号:US10980801

    申请日:2004-11-04

    IPC分类号: A61K31/095 A61K31/045

    CPC分类号: A61K31/41 A61K31/04 A61K31/52

    摘要: A patient in need of nitroglycerin therapy is treated with nitroglycerin and agent that prevents inhibition of or reverses inhibition of mtALDH and/or the generation of reactive oxygen species from mitochondria, e.g., a mitochondrial antioxidant which is not a reducing agent or a dithiol, e.g., ebselen or uric acid. Nitroglycerin dosage can be regulated and inhibiting agent dosage can be regulated and tolerance postponed by monitoring blood level of active mtALDH and dosing in response to determined level of active mtALDH.

    摘要翻译: 需要硝酸甘油治疗的患者用硝酸甘油和药剂治疗,其防止抑制或逆转mtALDH的抑制和/或从线粒体产生活性氧,例如不是还原剂或二硫醇的线粒体抗氧化剂,例如 ,依勃硒或尿酸。 通过监测活性mtALDH的血液水平和给药以响应确定的活性mtALDH水平,可以调节硝酸甘油剂量并且可以调节抑制剂剂量并进行耐受性推迟。

    Rotating strap
    4.
    外观设计

    公开(公告)号:USD1015920S1

    公开(公告)日:2024-02-27

    申请号:US29815994

    申请日:2021-11-18

    申请人: Zhiqiang Chen

    设计人: Zhiqiang Chen

    摘要: FIG. 1 is a top, front and right side perspective view of a rotating strap showing my new design;
    FIG. 2 is a top, rear and left side perspective thereof;
    FIG. 3 is a perspective view thereof, showing the rotating strap in the alternate state.
    FIG. 4 is a front elevational view thereof;
    FIG. 5 is a rear elevational view thereof;
    FIG. 6 is a left side elevational view thereof;
    FIG. 7 is a right side elevational view thereof;
    FIG. 8 is a top plan view thereof;
    FIG. 9 is a bottom plan view thereof;
    FIG. 10 is an enlarged view thereof, taken from encircled portion 10 in FIG. 1; and,
    FIG. 11 is an enlarged view thereof, taken from encircled portion 11 in FIG. 1.
    The broken lines in the drawings represent portions of the rotating strap and form no part of the claimed design. The other broken lines showing text represent indicia and form no part of the claimed design. The dot-dash broken lines in FIGS. 1, 10, and 11 are included to show a partially enlarged view only and form no part of the claimed design.

    Computer tomography imaging device and method
    5.
    发明授权
    Computer tomography imaging device and method 有权
    计算机断层扫描成像装置及方法

    公开(公告)号:US09380984B2

    公开(公告)日:2016-07-05

    申请号:US13322696

    申请日:2009-12-30

    摘要: The present invention discloses a method for performing CT imaging on a region of interest of an object under examination, comprising: acquiring the CT projection data of the region of interest; acquiring the CT projection data of region B; selecting a group of PI line segments covering the region of interest, and calculating the reconstruction image value for each PI line segment in the group; and combining the reconstruction image values in all the PI line segments to obtain the image of the region of interest. The present invention further discloses a CT imaging device using this method and a data processor therein. Since the 2D/3D slice image of the region of interest can be exactly reconstructed and obtained as long as the X-ray beam covers the region of interest and the region B, it is possible to use a small-sized detector to perform CT imaging on the region of interest at any position of a large-sized object, which reduces to a great extent the radiation dose of the X-ray during the CT scanning.

    摘要翻译: 本发明公开了一种对被检查物体的感兴趣区域进行CT成像的方法,包括:获取感兴趣区域的CT投影数据; 获取区域B的CT投影数据; 选择覆盖感兴趣区域的一组PI线段,并计算组中每个PI线段的重建图像值; 并且将所有PI线段中的重建图像值组合以获得感兴趣区域的图像。 本发明还公开了一种使用该方法的CT成像装置及其中的数据处理器。 由于只要X射线束覆盖感兴趣区域和区域B,就可以精确地重构和获得感兴趣区域的2D / 3D切片图像,因此可以使用小尺寸检测器来执行CT成像 在大尺寸物体的任何位置处的感兴趣区域,其在CT扫描期间在很大程度上降低X射线的辐射剂量。

    Concealed dangerous articles detection method and device
    6.
    发明授权
    Concealed dangerous articles detection method and device 有权
    隐藏危险品检测方法及装置

    公开(公告)号:US09194796B2

    公开(公告)日:2015-11-24

    申请号:US14008903

    申请日:2012-04-13

    摘要: A method and an apparatus for detecting hidden hazardous substance including the steps of: performing terahertz imaging for a detected object; judging whether there is a suspicious area containing the hidden hazardous substance in a terahertz image of the detected object obtained by the terahertz imaging; performing a multi-wavelength spectroscopy measurement to the suspicious area, determining whether the hazardous substance is contained in the suspicious area according to results of multi-wavelength spectroscopy measurement; and outputting the image of the detected object and hazardous substance detecting result. Also disclosed is an apparatus for implementing the method for detecting the hidden hazardous substance according to the present invention. Determination of the hidden hazardous substance can be performed from the perspectives of shape features and substance composition, thus the accuracy of detection is greatly increased.

    摘要翻译: 一种用于检测隐藏的有害物质的方法和装置,包括以下步骤:对检测到的物体执行太赫兹成像; 判断在通过太赫兹成像获得的检测对象的太赫兹图像中是否存在含有隐藏的有害物质的可疑区域; 对可疑区域进行多波长光谱测量,根据多波长光谱测量结果确定有害物质是否包含在可疑区域; 并输出检测对象的图像和有害物质检测结果。 还公开了根据本发明的用于实施隐藏的有害物质检测方法的装置。 可以从形状特征和物质组成的角度来确定隐藏的有害物质,从而大大提高了检测的准确性。

    Radiation detector, imaging device and electrode structure thereof, and method for acquiring an image
    7.
    发明授权
    Radiation detector, imaging device and electrode structure thereof, and method for acquiring an image 有权
    辐射检测器,成像装置及其电极结构以及获取图像的方法

    公开(公告)号:US08785867B2

    公开(公告)日:2014-07-22

    申请号:US13174174

    申请日:2011-06-30

    IPC分类号: G01T1/24 H01L27/146

    摘要: The present invention discloses a radiation detector, an imaging device and an electrode structure thereof, and a method for acquiring an image. The radiation detector comprises: a radiation sensitive film, a top electrode on the radiation sensitive film, and an array of pixel units electrically coupled to the radiation sensitive film. Each pixel unit comprises: a pixel electrode (which is configured to collect a charge signal in a pixel area of the radiation sensitive film), a storage capacitor, a reset transistor, a buffer transistor, a column strobe transistor, and a row strobe transistor. The column strobe transistor and the row strobe transistor are connected in series between the buffer transistor and the signal line, and transfer the voltage signal of the corresponding pixel unit in response to a column strobe signal and a row strobe signal. The radiation detector may be used for, for example, X-ray digital imaging.

    摘要翻译: 本发明公开了一种放射线检测器,成像器件及其电极结构以及用于获取图像的方法。 辐射检测器包括:辐射敏感膜,辐射敏感膜上的顶部电极,以及电耦合到辐射敏感膜的像素单元阵列。 每个像素单元包括:像素电极(其被配置为在辐射敏感膜的像素区域中收集电荷信号),存储电容器,复位晶体管,缓冲晶体管,列选通晶体管和行选通晶体管 。 列选通晶体管和行选通晶体管串联连接在缓冲晶体管和信号线之间,并响应于列选通信号和行选通信号传送相应像素单元的电压信号。 辐射检测器可以用于例如X射线数字成像。

    BORON-COATED NEUTRON DETECTOR AND METHOD FOR MANUFACTURING THE SAME
    9.
    发明申请
    BORON-COATED NEUTRON DETECTOR AND METHOD FOR MANUFACTURING THE SAME 有权
    BORON涂层中性探测器及其制造方法

    公开(公告)号:US20140061490A1

    公开(公告)日:2014-03-06

    申请号:US14112692

    申请日:2012-04-13

    IPC分类号: G01T3/00

    摘要: A boron-coated neutron detector, comprising a cathode tube with a plurality of passages formed therein along its longitudinal direction, the inner wall of each passage being coated with boron material; an electrode wire serving as an anode and arranged longitudinally in each of the passages, the electrode wire adapted to be applied with high voltage; and an insulating end plate to which each end of the cathode tube is fixed, the electrode wire being fixed to the cathode tube via the insulating end plate. Preferably, the cathode tube is formed by jointing a plurality of boron-coated substrates. The boron-coated neutron detector increases the detection efficiency of the neutron detector, which may reach or even exceed the detection efficiency of the 3He neutron detector of the same size, and the cost thereof is much cheaper than the 3He neutron detector.

    摘要翻译: 一种硼涂覆的中子探测器,包括阴极管,其阴极管沿着其纵向方向形成在其中,多个通道在其中形成,每个通道的内壁涂覆有硼材料; 用作阳极的电极线,并且纵向地布置在每个通道中,电极线适于施加高电压; 以及绝缘端板,阴极管的每一端固定在该绝缘端板上,电极线通过绝缘端板固定在阴极管上。 优选地,阴极管通过连接多个硼涂覆的基底而形成。 硼覆盖的中子检测器提高了中子检测器的检测效率,这可能达到或甚至超过相同尺寸的3He中子检测器的检测效率,并且其成本比3He中子检测器便宜得多。

    Millimeter-wave receiving device
    10.
    发明授权
    Millimeter-wave receiving device 有权
    毫米波接收装置

    公开(公告)号:US08590406B2

    公开(公告)日:2013-11-26

    申请号:US13126047

    申请日:2010-12-28

    IPC分类号: G01N23/00

    CPC分类号: G01K11/006 G01N22/00

    摘要: Disclosed is a millimeter-wave receiving device. The device includes at least one radiometer; and a positioning assembly for holding the radiometer, wherein the positioning assembly comprises: a first positioning member having a first surface; a second positioning member having a second surface, the first surface of the first positioning member and the second surface of the second positioning member holding the radiometer in opposite to each other. With the configuration according to the present invention, the at least one radiometer in the millimeter-wave receiving device can be located in all of freedoms on basis of various design requirements of the radiation path to ensure that the radiometer can be arranged in desired receiving positions.

    摘要翻译: 公开了一种毫米波接收装置。 该装置包括至少一个辐射计; 以及用于保持所述辐射计的定位组件,其中所述定位组件包括:具有第一表面的第一定位构件; 具有第二表面的第二定位构件,第一定位构件的第一表面和保持辐射计的第二定位构件的第二表面彼此相对。 利用根据本发明的配置,毫米波接收装置中的至少一个辐射计可以基于辐射路径的各种设计要求而位于所有自由度中,以确保辐射计可以被布置在期望的接收位置 。