摘要:
A cost-effective configuration of a metal liner for a reinforced concrete pressure vessel is disclosed wherein only stud shear connectors and cooling tubes of the liner cooling system are used to anchor the liner and the passages provided in the liner and the wall of the vessel. In the areas of the introduction of forces, stud connectors of different stud rigidities are used. In the anchoring of loads which is again effected by stud connectors only, further transmission is obtained by means of reinforcing rods.
摘要:
A concrete reactor pressure vessel for a low capacity, gas cooled nuclear reactor is provided. To assure the safe containment of the cooling gas in an economical manner and to remove the heat generated in the reactor core, the pressure vessel is equipped with reinforcing or prestressing elements. Cooling gas transfers its heat to a heat exchanger means consisting of the liner of the pressure vessel and cooling pipes mounted on the concrete side of the liner with water flowing through the cooling pipes. The heat exchanger comprises on the secondary side at least two mutually independent systems, each provided with collector pipe means located outside the reactor pressrue vessel for the forerunnings and afterrunnings of the cooling water. Each cooling pipe is connected by means of an inlet and a drain line with the corressponding collector pipe means.
摘要:
A nuclear power plant with a gas cooled high temperature reactor, installed in a prestressed concrete pressure vessel with the operational and decay heat removal systems. The prestressed concrete pressure vessel has a thermal protection system, with a thermal insulating layer and a liner cooling system. The liner cooling system, which is includes water carrying cooling pipes, which along with intermediate heat exchangers and cooling water pumps make up a closed intermediate cooling loop used for removal of the decay heat in case a failure of the decay heat removal systems. The elements of the invention assure an adequate water flow for the removal of decay heat in the liner cooling system in any situation, i.e. such that the decay heat may also be removed by natural convection. These element insure a sufficient driving pressure differences and minimize pressure losses in the intermediate cooling loop.
摘要:
This invention provides a process for checking the removal rate of pyrogenic substances, in particular viruses, from organic material. The material to be purified is passed through an ultrafilter or an ultrafiltration unit whose virus-removal rate has already been determined by passing viruses of the Leviviridae family or other comparable small bacteriophages through the filter or filtration unit, the virus titer is determined before and after the filtration operation and the virus removal rate thus calculated. Before or after determining the virus-removal rate, a given pressure is applied to the filter or filtration unit in a gas pressure-hold test, and the decrease in the pressure over a given period is measured. After filtration of the biological material, the rate of virus removal by the filter is checked by repeating the pressure-hold test.
摘要:
By inserting the diskette cartridge into the drive mechanism an ejection slide is moved into a latched position against a spring force. The latching device becomes operative when the closure of the drive mechanism is closed and comprises a monostable pivotable member. The latching device is released by a pawl device which acts in one direction only and which is movable by the closure. The pawl device is set to a ready-to-release position for the latching device when the closure is closed and is moved so as to release the latching device when the closure is opened. The movement of the pawl device is used for detecting the release operation.
摘要:
The invention concerns a device for die-cutting a stack of sheet-like materials, particularly labels, whereby the stack is pressed into the die-cutter blade by a relative movement of a punching ram and a hollow cylindrical die-cutter blade.For a device such as this, it is proposed that the die-cutter blade 18 is adjustably held in a frame 16, and the frame 16 is accommodated by a receiving apparatus 13 which is mounted in a punch platen 12 and is adjustable relative to it, whereby the frame 16 can be slid in a plane parallel to the punch platen 12, in particular is adjustable in the direction of two major axes that are essentially arranged perpendicular to one another, and can also be tilted out of the plane.Such a device allows for precise orientation of the die-cutter blade relative to the stack to be punched.
摘要:
According to certain embodiments, the invention relates to a method of producing antibodies employing an immunoconjugate produced by conjugating at least one membrane-anchoring compound with at least one partial sequence of a viral, bacterial, or protoral protein. The immunoconjugate has the advantage that it can be stored for a very long time even without cooling. According to certain embodiments, the invention relates to an immunoconjugate for the specific induction of cytotoxic T-lymphocytes which comprises a conjugate from at least one membrane anchor compound and a protein, containing at least one killer T-cell epitope, of a virus, a bacterium, a parasite or a tumor antigen, or at least one partial sequence containing at least one killer T-cell epitope of a viral, bacterial or parasite protein or of a tumor antigen.
摘要:
A heat insulation system may protect surfaces along which a hot gas stream is conducted. The insulation may be several plies of slightly compressed ceramic fiber mats, separated by intermediate plates. Cover plates are attached to the hot side. The cover plates are mounted by holding bolts on the support structure carrying the insulation. The support structure may be the liner of a nuclear reactor pressure vessel. Thickness and size of the cover plates are optimized with regard to the stresses occurring at the edges of the holes provided for the holding bolts to ensure dimensional stability of the fiber mats and the functional capability of the metallic mounting system during a long period of time. Several sealing sleeves may be arranged on each holding bolt. In a first solution, some intermediate plates exhibit lug-shaped points stamped out of the plates on both sides in vertical areas of the heat insulation system. The lug-shaped points which transfer the forces of the fiber mats to the intermediate plates. In a second solution, the function of these intermediate plates may be taken over by layers of expanded metal arranged between the fiber mats.
摘要:
The present invention provides a method for preparation of a high concentration liquid formulation (HCLF) of an antibody or a fragment thereof. The present invention also relates to a method for stabilizing an anti-CD20 antibody or a fragment thereof in a liquid pharmaceutical formulation. Furthermore, the present invention relates to a liquid pharmaceutical formulation of a veltuzumab antibody or a fragment thereof comprising at least 155 mg/mL of a veltuzumab antibody or a fragment thereof.
摘要:
The invention relates to a device for die cutting a stack consisting of sheet-type materials, in particular labels. According to said method, a movement of a stack to be cut in relation to a hollow cylindrical be pushed into said die-cutter blade. This type of device is characterized in that the die-cutter blade (18) is adjustably mounted in a frame (16), which can be inserted in a holding device (13) perpendicularly to the relative displacement direction (K) of the stacks to be cut (7) and die-cutter blades (18), and can be fixed in a central position. The holding device (13) is mounted in a die-cutter head plate (12), in such a way that it can be adjusted in relation to the latter. A die-cutter device of this type has an extremely compact construction, as a result of the positioning and mounting of the die-cutter blade in the direction of the relative movement of the stack to be cut and the die-cutter blade.