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43 条记录 (耗时 0.026 秒)

    Variable charge films for controlling microfluidic flow
    1.
    发明授权
    Variable charge films for controlling microfluidic flow 有权
    用于控制微流体流动的可变电荷膜

    公开(公告)号：US07722752B2

    公开(公告)日：2010-05-25

    申请号：US11070770

    申请日：2005-03-02

    申请人： Joseph B. Schlenoff ,  Zhijie Sui

    发明人： Joseph B. Schlenoff ,  Zhijie Sui

    IPC分类号： G01N27/447 ,  G01N27/453 ,  B01D57/02

    CPC分类号： G01N27/44752

    摘要： A microfluidic device for carrying a liquid, the device comprising a microfluidic channel having an interior wall and a polyelectrolyte film on the interior wall whereby liquid carried by the channel contacts the polyelectrolyte film, the polyelectrolyte film having a thickness of about 1 to about 1000 nanometers and comprising an interpenetrating network of a predominantly positively charged polymer and a predominantly negatively charged polymer, the predominantly positively charged polymer, the predominantly negatively charged polymer or both containing (i) a pH insensitive positively or negatively charged repeat unit having a pKa greater than 9 or less than 3, and (ii) a pH sensitive repeat unit, the pH sensitive repeat unit having a pKa of 3 to 9, whereby the pH of liquid in the microfluidic channel may be used to control the velocity or direction of electroosmotic flow of the liquid within said microfluidic channel.

    摘要翻译： 一种用于携带液体的微流体装置，该装置包括在内壁上具有内壁和聚电解质膜的微流体通道，由该通道承载的液体接触该聚电解质膜，该聚电解质膜具有约1至约1000纳米的厚度 并且包含主要带正电荷的聚合物和主要带负电荷的聚合物的互穿网络，主要为带正电荷的聚合物，主要为带负电荷的聚合物或二者均包含（i）具有pKa大于9的pH不敏感的带正电荷或带负电荷的重复单元 或小于3，和（ii）pH敏感重复单元，pH敏感重复单元的pKa为3至9，由此微流体通道中液体的pH可用于控制电渗流速度或方向 所述微流体通道内的液体。

    Thin films for controlled protein interaction
    2.
    发明授权
    Thin films for controlled protein interaction 有权

    公开(公告)号：US08481017B2

    公开(公告)日：2013-07-09

    申请号：US11063952

    申请日：2005-02-23

    申请人： Joseph B. Schlenoff ,  Zhijie Sui ,  David S. Salloum ,  Hassan Rmaile

    发明人： Joseph B. Schlenoff ,  Zhijie Sui ,  David S. Salloum ,  Hassan Rmaile

    IPC分类号： A61K31/74

    CPC分类号： C02F1/4693 ,  G02B1/04 ,  C08L39/00

    摘要： A medium for isolating or releasing an electrostatically charged component from or into an aqueous composition. The medium has a polyelectrolyte film on at least one surface of an article wherein the polyelectrolyte film is characterized by an interpenetrating network of a predominantly positively charged polymer and a predominantly negatively charged polymer. The predominantly positively charged polymer, the predominantly negatively charged polymer or both contain (i) a pH sensitive imidazole repeat unit having a pKa between 3 and 9, or (ii) a redox sensitive repeat unit selected from the group consisting of quaternized bipyridine repeat units, coordinated metal repeat units, pyrrole repeat units, aniline repeat units, thiophene repeat units and combinations thereof having a redox potential between +1.2 volts and −1.2 volts versus a standard hydrogen electrode.

    Compacted polyelectrolyte complexes and articles
    3.
    发明授权
    Compacted polyelectrolyte complexes and articles 有权
    压实的聚电解质复合物和制品

    公开(公告)号：US08314158B2

    公开(公告)日：2012-11-20

    申请号：US13346272

    申请日：2012-01-09

    申请人： Joseph B. Schlenoff

    发明人： Joseph B. Schlenoff

    IPC分类号： C08J5/20 ,  C08J5/00 ,  B05D1/18 ,  B32B27/32 ,  B32B27/00

    CPC分类号： C08J5/20 ,  Y10T428/25 ,  Y10T428/31855

    摘要： This invention relates to an osmotically compacted polyelectrolyte complex having a first region and a second region, the first region having a greater modulus than the second region and a method for preparing such an article. The article comprising the polyelectrolyte complex is produced by contacting a polyelectrolyte complex with a solution comprising an osmolyte at a concentration sufficient to compact the polyelectrolyte complex. The compaction process is terminated before the entire article is osmotically compacted.

    摘要翻译： 本发明涉及具有第一区域和第二区域的渗透压缩的聚电解质络合物，第一区域具有比第二区域更大的模量和制备这种制品的方法。 包含聚电解质络合物的制品是通过使聚电解质络合物与包含渗透剂的溶液接触，所述溶液的浓度足以压实聚电解质络合物。 压实过程在整个物品渗透压实之前终止。

    HYDROPHOBIC FLUORINATED POLYELECTROLYTE COMPLEX FILMS AND ASSOCIATED METHODS
    5.
    发明申请
    HYDROPHOBIC FLUORINATED POLYELECTROLYTE COMPLEX FILMS AND ASSOCIATED METHODS 审中-公开
    疏水性氟化复合膜和相关方法

    公开(公告)号：US20120094020A1

    公开(公告)日：2012-04-19

    申请号：US13312417

    申请日：2011-12-06

    申请人： Joseph B. Schlenoff

    发明人： Joseph B. Schlenoff

    IPC分类号： B05D1/00 ,  B05D7/00 ,  B05D1/18 ,  B05D1/02 ,  B05D1/28

    CPC分类号： C08F8/20 ,  B82Y30/00 ,  Y10T428/3154 ,  Y10T428/31544

    摘要： A method for controlling the hydrophobicity of a surface of an article by alternately depositing solutions comprising net positively charged polymers and net negatively charged polymers onto the surface to form a polyelectrolyte film of an interpenetrating network of net positively charged polymers and net negatively charged polymers on the surface of the article.

    摘要翻译： 通过将表面上带有带正电荷的聚合物和带负电荷的聚合物交替沉积的溶液交替沉积在表面上以形成网络带正电的聚合物和带负电荷的聚合物的互穿网络的聚电解质膜来控制制品表面疏水性的方法 表面的物品。

    HYDROPHOBIC FLUORINATED POLYELECTROLYTE COMPLEX FILMS AND ASSOCIATED METHODS
    6.
    发明申请
    HYDROPHOBIC FLUORINATED POLYELECTROLYTE COMPLEX FILMS AND ASSOCIATED METHODS 有权
    疏水性氟化复合膜和相关方法

    公开(公告)号：US20100173224A1

    公开(公告)日：2010-07-08

    申请号：US12727930

    申请日：2010-03-19

    申请人： Joseph B. Schlenoff

    发明人： Joseph B. Schlenoff

    IPC分类号： H01M8/10

    CPC分类号： C08F8/20 ,  B82Y30/00 ,  Y10T428/3154 ,  Y10T428/31544

    摘要： A fuel cell comprising a proton transporting membrane is provided. The proton transporting membrane comprises a polyelectrolyte film comprising a multilayer comprising an interpenetrating network of a net positively charged polyelectrolyte polymer comprising repeat units with at least two fluorine atoms and a net negatively charged polyelectrolyte polymer comprising repeat units with at least two fluorine atoms, and further comprising a fluorinated counterion within the multilayer.

    摘要翻译： 提供了包含质子传递膜的燃料电池。 质子传输膜包括聚电解质膜，其包含多层，其包含具有至少两个氟原子的重复单元的净正电荷聚电解质聚合物的互穿网络和包含具有至少两个氟原子的重复单元的净负电聚合电解质聚合物， 包括多层内的氟化抗衡离子。

    Apparatus for capillary electrophoresis and associated method
    7.
    发明授权
    Apparatus for capillary electrophoresis and associated method 失效
    毛细管电泳装置及相关方法

    公开(公告)号：US06841054B2

    公开(公告)日：2005-01-11

    申请号：US10145161

    申请日：2002-05-14

    申请人： Joseph B. Schlenoff ,  Timothy W. Graul

    发明人： Joseph B. Schlenoff ,  Timothy W. Graul

    IPC分类号： G01N27/447 ,  B01D61/42

    CPC分类号： G01N27/44752 ,  Y10T428/131 ,  Y10T428/1317 ,  Y10T428/1321 ,  Y10T428/1359 ,  Y10T436/25375

    摘要： An apparatus and method for capillary zone electrophoresis includes a polyelectrolyte multilayer positioned in a capillary tube for analytical separations of macromolecules. The capillary comprises a passage defined by passage walls comprising fused silica. The polyelectrolyte multilayer is positioned within the passage adjacent the walls, and comprises an organic polyelectrolyte. The passage may further comprise nonporous silica particles coated with a multilayer including a plurality of polyelectrolyte layers. An apparatus includes a power supply having a positive electrode and a negative electrode for generating an electric field therebetween. The apparatus includes a capillary having a passage formed by passage walls and comprising therein a polyelectrolyte multilayer positioned substantially within the passage. The passage has a first end electrically connected to the positive electrode and a second end electrically connected to the negative electrode to thereby generate an electric field through the passage. The apparatus also includes a sensor positioned adjacent the passage for sensing macromolecules.

    摘要翻译： 用于毛细管区带电泳的装置和方法包括定位在用于大分子分析分离的毛细管中的聚电解质多层。 毛细管包括由包含熔融二氧化硅的通道壁限定的通道。 聚电解质多层位于邻近壁的通道内，并且包含有机聚电解质。 通道还可以包括涂覆有包含多个聚电解质层的多层的无孔二氧化硅颗粒。 一种装置包括具有用于在其间产生电场的正极和负极的电源。 该装置包括毛细管，该毛细管具有由通道壁形成的通道，并在其中包括基本上位于通道内的聚电解质多层。 通道具有电连接到正极的第一端和与负极电连接的第二端，从而通过通道产生电场。 该装置还包括位于通道附近的用于感测大分子的传感器。

    Specimen holder
    9.
    发明授权
    Specimen holder 失效
    标本持有人

    公开(公告)号：US5181233A

    公开(公告)日：1993-01-19

    申请号：US790203

    申请日：1991-11-08

    申请人： William J. Rink ,  Joseph B. Schlenoff ,  Haim H. G. Mathias

    发明人： William J. Rink ,  Joseph B. Schlenoff ,  Haim H. G. Mathias

    IPC分类号： A61M25/01 ,  G01N23/20

    CPC分类号： G01N23/20025 ,  A61M25/0136

    摘要： A specimen holder including a housing having a specimen chamber in it. A window defining a wall of the chamber allows transmission of at least a portion of the x-radiation from X-ray diffraction spectometry apparatus on which the holder is mounted, into the chamber. The housing has a passageway in it opening at one end into the specimen chamber and at the opposite end to outside the housing. A cylindrical specimen mount supports the specimen in the housing is constructed for sealing sliding reception in the passageway such that the specimen mount is rotatable about its longitudinal axis and movable lengthwise of the passageway while maintaining a seal with the passageway for positioning the specimen in the specimen chamber.

    摘要翻译： 一种样品架，包括在其中具有试样室的壳体。 限定室的壁的窗口允许将来自安装有保持器的X射线衍射光谱装置的X射线的至少一部分透射到腔室中。 壳体具有一个通道，其一端在试样室中开口并且在相对端部处于壳体外部。 圆柱形样品支架支撑壳体中的样本被构造用于密封通道中的滑动接收，使得样本支架能够围绕其纵向轴线旋转并且可在通道的纵向方向上旋转，同时保持用于将样本定位在样本中的通道的密封 房间。

    COMPACTED POLYELECTROLYTE COMPLEXES AND ARTICLES
    10.
    发明申请
    COMPACTED POLYELECTROLYTE COMPLEXES AND ARTICLES 有权
    压电聚合物复合物和制品

    公开(公告)号：US20120108685A1

    公开(公告)日：2012-05-03

    申请号：US13346287

    申请日：2012-01-09

    申请人： Joseph B. Schlenoff

    发明人： Joseph B. Schlenoff

    IPC分类号： C08J5/20

    CPC分类号： C08J5/20 ,  Y10T428/25 ,  Y10T428/31855

    摘要： A method is described for producing an osmotically compacted polyelectrolyte complex having a first region and a second region, the first region having a greater modulus than the second region. The method comprises contacting an article comprising polyelectrolyte complex to a solution comprising a preferred osmolyte of concentration sufficient to compact said polyelectrolyte complex and terminating the compaction process before the entire article is osmotically compacted.A method is also described for producing a article comprising water and an intermolecular blend of at least one positively charged polyelectrolyte polymer and at least one negatively charged polymer, said article having a core region and a surface region, the surface region having at least twice the elastic modulus of the core region, the method comprising contacting a starting article comprising a blend of said polymers with a solution of osmolyte, wherein the osmolyte is excluded from said article.

    摘要翻译： 描述了一种制备具有第一区域和第二区域的渗透压缩的聚电解质络合物的方法，第一区域具有比第二区域更大的模量。 该方法包括将包含聚电解质络合物的制品与含有足以压制所述聚电解质复合物的浓度的优选渗透剂的溶液接触，并在整个制品渗透压实之前终止压实过程。 还描述了一种用于生产包含至少一种带正电荷的聚电解质聚合物和至少一种带负电荷的聚合物的水和分子间共混物的制品的方法，所述制品具有芯区域和表面区域，所述表面区域具有至少两倍于 芯区域的弹性模量，该方法包括将包含所述聚合物的共混物的起始制品与渗透剂溶液接触，其中渗透剂被排除在所述制品之外。