2′, 5′-oligoadenylate phosphodiesterase
    3.
    发明授权
    2′, 5′-oligoadenylate phosphodiesterase 失效
    2',5'-寡腺苷酸磷酸二酯酶

    公开(公告)号:US07592140B2

    公开(公告)日:2009-09-22

    申请号:US11078951

    申请日:2005-03-11

    IPC分类号: C12N15/55 C12Q1/68 C12N9/16

    摘要: Polypeptides having 2′,5′-oligoadenylate phosphodiesterase activity, antibodies against the polypeptides, polynucleotides coding for the polypeptides, recombinant plasmid DNAs into which the polynucleotides have been inserted, host cells transformed by the recombinant plasmid DNAs, processes for screening for 2′,5′-oligoadenylate phosphodiesterase activity inhibitor substances, and processes for screening for 2′,5′-oligoadenylate phosphodiesterase expression regulation inhibitor substances. The polypeptides, polynucleotides and host cells are useful for searching for therapeutic agents for viral infections and tumors.

    摘要翻译: 具有2',5'-寡腺苷酸磷酸二酯酶活性的多肽,针对多肽的抗体,编码多肽的多核苷酸,插入多核苷酸的重组质粒DNA,由重组质粒DNA转化的宿主细胞,筛选2', 5'-寡腺苷酸磷酸二酯酶活性抑制剂物质,以及筛选2',5'-寡腺苷酸磷酸二酯酶表达调节抑制物质的方法。 多肽,多核苷酸和宿主细胞可用于寻找病毒感染和肿瘤的治疗剂。

    2', 5'-oligoadenylate phosphodiesterase
    4.
    发明申请
    2', 5'-oligoadenylate phosphodiesterase 失效
    2',5'-寡腺苷酸磷酸二酯酶

    公开(公告)号:US20050272119A1

    公开(公告)日:2005-12-08

    申请号:US11078951

    申请日:2005-03-11

    摘要: Polypeptides having 2′,5′-oligoadenylate phosphodiesterase activity, antibodies against the polypeptides, polynucleotides coding for the polypeptides, recombinant plasmid DNAs into which the polynucleotides have been inserted, host cells transformed by the recombinant plasmid DNAs, processes for screening for 2′,5′-oligoadenylate phosphodiesterase activity inhibitor substances, and processes for screening for 2′,5′-oligoadenylate phosphodiesterase expression regulation inhibitor substances. The polypeptides, polynucleotides and host cells are useful for searching for therapeutic agents for viral infections and tumors.

    摘要翻译: 具有2',5'-寡腺苷酸磷酸二酯酶活性的多肽,针对多肽的抗体,编码多肽的多核苷酸,插入多核苷酸的重组质粒DNA,由重组质粒DNA转化的宿主细胞,筛选2', 5'-寡腺苷酸磷酸二酯酶活性抑制剂物质,以及筛选2',5'-寡腺苷酸磷酸二酯酶表达调节抑制物质的方法。 多肽,多核苷酸和宿主细胞可用于寻找病毒感染和肿瘤的治疗剂。