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    Infusion devices and method
    1.
    发明授权
    Infusion devices and method 有权
    输液装置及方法

    公开(公告)号：US06939322B2

    公开(公告)日：2005-09-06

    申请号：US10621378

    申请日：2003-07-18

    申请人： Justin Crank ,  Scott Larson ,  Timothy J. Mickley

    发明人： Justin Crank ,  Scott Larson ,  Timothy J. Mickley

    IPC分类号： A61J1/00 ,  A61J1/14 ,  A61M5/46 ,  A61M25/00 ,  A61M25/01 ,  A61M25/06 ,  A61M25/098 ,  A61M5/00

    CPC分类号： A61M25/0068 ,  A61J1/1406 ,  A61M5/46 ,  A61M25/0074 ,  A61M25/0084 ,  A61M25/0108 ,  A61M25/0662 ,  A61M2025/0008 ,  A61M2025/0081 ,  A61M2025/0085 ,  A61M2025/0086 ,  A61M2025/0091 ,  A61M2205/19 ,  A61M2210/125

    摘要： Myocardial revascularization catheters and methods are provided herein. Catheters in accord with the present invention may include an outer shaft and an inner shaft where the inner shaft may be slidably and rotatably disposed in the outer shaft and the distal movement of the inner shaft may be arrested by the engagement of stops and catches located within the inner and outer shaft Methods in accord with the current invention may include providing a therapeutic, providing a radiopaque contrast media, injecting the therapeutic through a lumen into the myocardium of the heart, and injecting the radiopaque contrast media through a lumen into myocardium of the heart. In this example, the location of the injection the radiopaque material may be chosen to indicate the injection point of the injection of the therapeutic.

    摘要翻译： 本文提供了心肌血运重建导管和方法。 根据本发明的导管可以包括外轴和内轴，其中内轴可以可滑动地和可旋转地设置在外轴中，并且内轴的远端运动可以通过位于内部的止动件和卡扣的接合来阻止 根据本发明的内外轴方法可以包括提供治疗剂，提供不透射线的造影剂，通过内腔将治疗剂注射到心脏的心肌中，以及将不透射线的造影剂通过内腔注射到心脏的心肌中 心。 在该示例中，可以选择注射不透射线材料的位置以指示治疗剂的注射的注射点。

    Infusion devices and method
    2.
    发明授权
    Infusion devices and method 失效

    公开(公告)号：US06616626B2

    公开(公告)日：2003-09-09

    申请号：US09747157

    申请日：2000-12-21

    申请人： Justin Crank ,  Scott Larson ,  Timothy J. Mickley

    发明人： Justin Crank ,  Scott Larson ,  Timothy J. Mickley

    IPC分类号： A61M3100

    CPC分类号： A61M25/0068 ,  A61J1/1406 ,  A61M5/46 ,  A61M25/0074 ,  A61M25/0084 ,  A61M25/0108 ,  A61M25/0662 ,  A61M2025/0008 ,  A61M2025/0081 ,  A61M2025/0085 ,  A61M2025/0086 ,  A61M2025/0091 ,  A61M2205/19 ,  A61M2210/125

    摘要： Devices and methods for performing improved percutaneous myocardial revascularization (PMR) procedures. One device includes a preassembled PMR drug delivery catheter and a drug neutralizing vial. The vial assembly allows prepping the PMR catheter by flushing drug through distal needle, and into a vial cavity where the drug is neutralized by a neutralizing agent. One set of devices includes needles having protrusions secured to the distal regions of drug delivery tubes. One needle has outward protruding barbs engaging the inner tube wall while another needle has outward threads which can screw into the tube inner wall. Radiopaque marker bands are also included in the present invention which are asymmetrically distributed on the catheter shaft, allowing a treating physician to determine under fluoroscopy whether the catheter distal region is pointed away or toward the treating physician, as well as determining whether the catheter distal region is rotated toward or away from the treating physician. PMR devices include catheters having dual injection needles, for both injecting a drug into the heart wall and a radiopaque contrast media to mark the already treated sites. One PMR injection device has multiple stops for allowing controlled, variable needle depth penetration with a single distal needle tip.

    Elongated medical device with functional distal end
    3.
    发明授权
    Elongated medical device with functional distal end 有权
    具有功能性远端的细长的医疗装置

    公开(公告)号：US07544183B2

    公开(公告)日：2009-06-09

    申请号：US11360764

    申请日：2006-02-24

    申请人： Matthew Hawk ,  Scott Larson ,  Timothy J. Mickley ,  Chad Harris

    发明人： Matthew Hawk ,  Scott Larson ,  Timothy J. Mickley ,  Chad Harris

    IPC分类号： A61M5/178

    CPC分类号： A61M25/0069 ,  A61B17/3478 ,  A61B2017/00247 ,  A61B2017/22069 ,  A61B2017/22077 ,  A61B2017/348 ,  A61B2017/3488 ,  A61B2018/00392 ,  A61B2018/00738 ,  A61B2090/036 ,  A61B2218/002 ,  A61M25/10 ,  A61M2025/1093

    摘要： An elongate medical device that may be used for performing medical procedures on a patient is provided. This elongate medical device may include a first member having a distal end, an outer surface, and a first lumen, where the first member may have an elongated configuration such that the length of the first member is at least ten times greater than the width of the first member. The elongate medical device may also have a second member positioned within the first member and a hood stop. The hood stop in this device may be positioned within the first member and may have a distal region and a shoulder region where the shoulder region may be configured to limit the travel of the first member or the second member past the hood stop.

    摘要翻译： 提供了可用于对患者执行医疗程序的细长医疗装置。 该细长的医疗装置可以包括具有远端，外表面和第一内腔的第一构件，其中第一构件可以具有细长构造，使得第一构件的长度比第一构件的宽度大至少十倍 第一个成员。 细长医疗装置还可以具有定位在第一构件内的第二构件和罩止动件。 该装置中的罩止挡件可以定位在第一构件内并且可以具有远侧区域和肩部区域，其中肩部区域可以被配置为限制第一构件或第二构件经过罩止挡件的移动。

    Variable tip catheter
    4.
    发明授权
    Variable tip catheter 失效
    可变尖端导管

    公开(公告)号：US06582400B1

    公开(公告)日：2003-06-24

    申请号：US09695527

    申请日：2000-10-24

    申请人： Matthew Hawk ,  Scott Larson ,  Timothy J. Mickley ,  Chad Harris

    发明人： Matthew Hawk ,  Scott Larson ,  Timothy J. Mickley ,  Chad Harris

    IPC分类号： A61M5178

    CPC分类号： A61M25/0069 ,  A61B17/3478 ,  A61B2017/00247 ,  A61B2017/22069 ,  A61B2017/22077 ,  A61B2017/348 ,  A61B2017/3488 ,  A61B2018/00392 ,  A61B2018/00738 ,  A61B2090/036 ,  A61B2218/002 ,  A61M25/10 ,  A61M2025/1093

    摘要： Therapeutic catheters for increasing myocardial blood perfusion in procedures including percutaneous myocardial revascularization (PMR), which can include tips for cutting into the myocardium to stimulate a healing response and/or for injecting angiogenic substances. PMR catheters can include an outer shaft slidably housing an inner shaft having a distal therapeutic tip. The outer shaft can be slidably disposed in a guide catheter and have an expandable atraumatic distal tip for presenting an enlarged distal profile against the heart chamber wall. The enlarged atraumatic profile can reduce the likelihood of the outer shaft penetrating undesirably into the myocardium. One expandable distal tip expands radially when forced against the endocardium. Another expandable tip expands when unconstrained by the guide catheter. Yet another expandable tip expands when manipulated by an elongate manipulation member.

    摘要翻译： 用于在包括经皮心肌血运重建（PMR）的手术中增加心肌血液灌注的治疗导管，其可以包括切入心肌以刺激愈合反应和/或注射血管生成物质的尖端。 PMR导管可以包括可滑动地容纳具有远侧治疗末端的内轴的外轴。 外轴可以可滑动地设置在引导导管中并且具有可膨胀的无创伤的远侧末端，用于呈现抵靠心室壁的扩大的远端轮廓。 扩大的无创伤轮廓可以减少外轴不期望地进入心肌的可能性。 一个可扩展的远侧末端在被迫靠在心内膜上时径向扩张。 当引导导管不受约束时，另一个可扩展的尖端膨胀。 当由细长的操纵构件操纵时，另一个可膨胀尖端膨胀。

    Catheter shaft assembly
    7.
    发明授权
    Catheter shaft assembly 有权
    导管轴总成

    公开(公告)号：US06893421B1

    公开(公告)日：2005-05-17

    申请号：US09635083

    申请日：2000-08-08

    申请人： Scott Larson ,  Justin Crank ,  Matthew Hawk ,  Bradley Slaker

    发明人： Scott Larson ,  Justin Crank ,  Matthew Hawk ,  Bradley Slaker

    IPC分类号： A61M25/00 ,  A61M5/178

    CPC分类号： A61M25/0023 ,  A61M25/0021 ,  A61M25/0043 ,  A61M25/0084 ,  A61M2025/0089

    摘要： A catheter shaft assembly is disclosed. A catheter shaft in accordance with the present invention comprises a first elongate shaft having an inner surface defining a lumen, a second elongate shaft slidingly disposed within the lumen of the first elongate shaft, at least one interstitial member disposed between the inner surface of the first elongate shaft and the outer surface of the second elongate shaft.

    摘要翻译： 公开了一种导管轴组件。 根据本发明的导管轴包括具有限定内腔的内表面的第一细长轴，滑动地设置在第一细长轴的内腔内的第二细长轴，设置在第一细长轴的内表面之间的至少一个间隙构件 细长轴和第二细长轴的外表面。

    Catheter assembly
    8.
    发明申请
    Catheter assembly 审中-公开
    导管总成

    公开(公告)号：US20050065474A1

    公开(公告)日：2005-03-24

    申请号：US10979233

    申请日：2004-11-03

    申请人： Scott Larson ,  Justin Crank ,  Matthew Hawk ,  Bradley Slaker

    发明人： Scott Larson ,  Justin Crank ,  Matthew Hawk ,  Bradley Slaker

    IPC分类号： A61M25/00 ,  A61M5/178

    CPC分类号： A61M25/0023 ,  A61M25/0021 ,  A61M25/0043 ,  A61M25/0084 ,  A61M2025/0089

    摘要： A catheter assembly is disclosed. This assembly may include a first elongate member having an internal lumen and a distal portion, a second elongate member, slidable within the first elongate member, and a spacer positioned between the second elongate member and the first elongate member. In this example, the spacer may be positioned at bendable portions of the first elongate member and the second elongate member such that the spacer maintains a substantially uniform spacing between the second elongate member and the first elongate member when the first elongate member and the second elongate member are in a curved orientation.

    摘要翻译： 公开了导管组件。 该组件可以包括具有内腔和远端部分的第一细长构件，在第一细长构件内可滑动的第二细长构件以及定位在第二细长构件和第一细长构件之间的间隔件。 在该示例中，间隔件可以定位在第一细长构件和第二细长构件的可弯曲部分处，使得当第一细长构件和第二细长构件与第二细长构件之间时，间隔件在第二细长构件和第一细长构件之间保持基本均匀的间隔 会员处于弯曲的方向。

    Infusion device and method
    9.
    发明申请
    Infusion device and method 审中-公开
    输液装置及方法

    公开(公告)号：US20050261667A1

    公开(公告)日：2005-11-24

    申请号：US11191053

    申请日：2005-07-28

    申请人： Justin Crank ,  Scott Larson ,  Timothy Mickley

    发明人： Justin Crank ,  Scott Larson ,  Timothy Mickley

    IPC分类号： A61J1/00 ,  A61J1/14 ,  A61M5/46 ,  A61M25/00 ,  A61M25/01 ,  A61M25/06 ,  A61M25/098

    CPC分类号： A61M25/0068 ,  A61J1/1406 ,  A61M5/46 ,  A61M25/0074 ,  A61M25/0084 ,  A61M25/0108 ,  A61M25/0662 ,  A61M2025/0008 ,  A61M2025/0081 ,  A61M2025/0085 ,  A61M2025/0086 ,  A61M2025/0091 ,  A61M2205/19 ,  A61M2210/125

    摘要： Devices and methods for performing improved percutaneous myocardial revascularization (PMR) procedures. One device includes a preassembled PMR drug delivery catheter and a drug neutralizing vial. The vial assembly allows prepping the PMR catheter by flushing drug through distal needle, and into a vial cavity where the drug is neutralized by a neutralizing agent. One set of devices includes needles having protrusions secured to the distal regions of drug delivery tubes. One needle has outward protruding barbs engaging the inner tube wall while another needle has outward threads which can screw into the tube inner wall. Radiopaque marker bands are also included in the present invention which are asymmetrically distributed on the catheter shaft, allowing a treating physician to determine under fluoroscopy whether the catheter distal region is pointed away or toward the treating physician, as well as determining whether the catheter distal region is rotated toward or away from the treating physician. PMR devices include catheters having dual injection needles, for both injecting a drug into the heart wall and a radiopaque contrast media to mark the already treated sites. One PMR injection device has multiple stops for allowing controlled, variable needle depth penetration with a single distal needle tip.

    摘要翻译： 用于进行改善的经皮心肌血运重建（PMR）手术的装置和方法。 一个装置包括预组装的PMR药物递送导管和药物中和小瓶。 小瓶组件允许通过将药物通过远端针头冲洗并进入药物中和药物的小瓶腔中来准备PMR导管。 一组装置包括具有固定到药物输送管的远侧区域的突起的针。 一针具有与内管壁接合的向外突出的倒钩，而另一针具有能够拧入管内壁的外螺纹。 不透射线标记带也包括在本发明中，其不对称地分布在导管轴上，允许治疗医师在透视下确定导管远端区域是指尖的还是朝向治疗医师，以及确定导管远端区域 被转向或远离治疗医师。 PMR装置包括具有双注射针的导管，用于将药物注射到心脏壁中，以及不透射线造影剂以标记已经治疗的部位。 一个PMR注射装置具有多个止动件，用于允许用单个远端针尖进行可控的，可变的针深度穿透。