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公开(公告)号：US10932891B2
公开(公告)日：2021-03-02
申请号：US15310471
申请日：2015-05-08
发明人： Milica Kovacevic-Milivojevic , Bart Gottenbos , Marco Baragona , Sergei Shulepov , Valentina Lavezzo , Guido Antonius Theodorus Adriaensen
IPC分类号： A61C17/028 , A61C17/02 , A61C15/00
摘要： A nozzle (12) for an oral irrigator device (10) having a guidance tip (34) with at least one orifice (36) at one end, and a nozzle spacer assembly (58) positioned around the at least one orifice (36). The at least one orifice is configured to expel a fluid as one of a jet, a spray, or any combination thereof. The nozzle spacer assembly (58) comprises at least two pairs of pliable spacers (60) that extend from the surface (35) for ensuring that the area at an entrance of an interproximal space between two teeth are treated, and (ii) establishing an improved angle of impact of the fluid expelled from the orifice.
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公开(公告)号：US10588391B2
公开(公告)日：2020-03-17
申请号：US16083222
申请日：2017-02-10
发明人： Jonathan Alambra Palero , Marco Baragona , Babu Varghese , Tim Tielemans , Johan Lub , Wouter Hendrik Cornelis Spoorendonk
摘要： In a hair styling device (20), a light emitting diode (33) is configured to deliver optical energy to hair, wherein an energy fluence of the optical energy is between 0.5 and 9 J/cm2, and more preferably between 1 and 5 J/cm2. The light emitting diode (33) is pulse-driven, and a pulse width of the optical energy is at least 50 ms. An output wavelength of the optical energy may be between 400 and 900 nm. The pulse width of the optical energy is preferably between 50 and 300 ms. The hair styling device (20) may comprise an optical shield (32) configured to block stray light during light exposure of the hair. An inner surface of the optical shield (32) may be reflective and/or may have a parabolic shape. The optical shield (32) may be movable between an open position in which a lock of hair can be placed in the hair styling device (20) while the optical energy is not applied, and a closed position in which light is prevented from escaping the hair styling device (20) while the optical energy is applied to the hair. The hair styling device may be a hair straightener having opposing first and second straightening surfaces, of which at least the first straightening surface comprises the light emitting diode (33), and at least the second straightening surface is arranged for reflecting light from the light emitting diode (33).
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公开(公告)号：US11819679B2
公开(公告)日：2023-11-21
申请号：US15314993
申请日：2015-06-03
CPC分类号： A61N1/00 , A61B18/14 , A61N1/0476 , A61N1/18 , A61N1/328 , A61N1/403 , A61B2018/0047
摘要： A device for RF skin treatment includes an outer electrode arranged on an operational side of the device. The outer electrode has an annular or equilateral polygonal shape. An inner electrode is arranged at a center of the outer electrode and is surrounded by the outer electrode. An RF generator is arranged to supply an RF treatment voltage between the inner electrode and the outer electrode. A skin contact surface of the inner electrode has a largest cross-sectional dimension in a range of 200-500 μm, and the RF treatment voltage is less than 50 V.
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公开(公告)号：US20220296834A1
公开(公告)日：2022-09-22
申请号：US17667606
申请日：2022-02-09
摘要： A system is for analyzing physical characteristics of mucus, in particular during patient respiratory support using a ventilator. A ventilation waveform is sensed and analyzed and an estimate of, or a change in, at least one mucus characteristic can then be determined.
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公开(公告)号：US20220087895A1
公开(公告)日：2022-03-24
申请号：US17399393
申请日：2021-08-11
发明人： Kiran Hamilton J. Dellimore , Harold Johannes Antonius Brans , Albertus Cornelis Den Brinker , Okke Ouweltjes , Pascal De Graaf , Marco Baragona , Samer Bou Jawde
摘要： According to an aspect, there is provided a wearable device, the wearable device comprising: an inflatable body configured to be mounted to a torso of a user; a first sensing device, wherein the first sensing device comprises a first sensor and a first actuator coupling the first sensor to the inflatable body; and a memory storing computer-readable instructions that, when executed, cause the wearable device to: inflate the inflatable body from a first state of the inflatable body to a second state of the inflatable body; actuate the first actuator from a first state of the first actuator to a second state of the first actuator, wherein actuating the first actuator from the first state of the first actuator to the second state of the first actuator reduces a volume of a first air gap between the torso and the first sensor; and while the inflatable body is in the second state of the inflatable body and the first actuator is in the second state of the first actuator receive a first signal from the first sensor. There is also described a method of using the wearable device.
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公开(公告)号：US20210012887A1
公开(公告)日：2021-01-14
申请号：US16980906
申请日：2019-03-06
摘要： A method (12) of estimating one or more physiological parameters, in particular of a cardiac region, based on medical imaging data. An input time series of three-dimensional medical images is received (14), representative of a cardiac region of a patient. A meshless simulation frame-work is applied (16) for simulating blood flow through at least a portion of the anatomical area captured by the images. The simulation framework comprises in particular simulating force interactions between individual elements of a simulated fluid (representing blood) and individual patches of a tissue structure of the imaged cardiac region. One or more physiological parameters (18) are derived based on the simulated blood flow.
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公开(公告)号：US11596349B2
公开(公告)日：2023-03-07
申请号：US16957132
申请日：2018-12-20
IPC分类号： A61B5/05 , A61B5/00 , A61B5/0537
摘要： There is provided a system (100) and method for determining a water or lipid level of skin. The system (100) comprises at least two electrodes (108) suitable for contacting skin, and a signal generator (106) configured to generate an electrical signal at a frequency across the at least two electrodes (108). The system (100) is configured to measure a permittivity between the at least two electrodes (108). The system (100) is further configured to determine a water or lipid level of skin based on the measured permittivity and the frequency of the electrical signal.
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公开(公告)号：US20220331200A1
公开(公告)日：2022-10-20
申请号：US17689046
申请日：2022-03-08
发明人： Harold Johannes Antonius Brans , Kiran Hamilton J. Dellimore , Samer Bou Jawde , Marco Baragona
摘要： Described herein are methods, devices and systems for respiratory therapy delivered by a therapy vest. A therapy vest is provided in which an independent body fitting function is provided by use of a body fit layer or compartment(s). The body fit layer or compartment(s) may be controlled independently from the therapy layer or compartment(s), such that the fit of the therapy vest is placed on more equal footing with the therapy delivering components of the therapy vest. Other examples are disclosed and claimed.
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公开(公告)号：US20220176155A1
公开(公告)日：2022-06-09
申请号：US17598626
申请日：2020-04-01
发明人： Alfonso Agatino Isola , Marco Baragona , Guillaume Leopold Theodorus Frederik Hautvast , Christoph Neukirchen
摘要： The invention relates to a system for assisting in planning a focal therapy treatment of a structure (1) within a patient body (2) by applying a treatment quantity using one or more devices (4a,b,c) operated in one or more device positions. The system comprises a unit (10) configured to generate a constraint function representing clinical objectives relating to the treatment quantity, a selection unit (11) configured to determine, for each of at least some non-selected candidate device positions, a sum of negative derivatives of the constraint function with respect to the treatment parameter associated with the respective device position and to select a device position for use in the treatment based on a comparison of the determined sums, and an optimization unit (12; 408) configured to determine at least one optimized treatment parameter for the selected device position based on the constraint function.
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10.发明授权公开(公告)号：US11179565B2
公开(公告)日：2021-11-23
申请号：US15563982
申请日：2016-03-29
发明人： Jonathan Alambra Palero , Ralph Timotheus Huijgen , Martin Jurna , Babu Varghese , Marco Baragona , Hendrik Halling Van Amerongen
摘要： The invention provides a non-invasive skin treatment device (100) comprising an r.f. treatment electrode (10); a return electrode (40); an r.f. generator (20) configured and arranged such that, during treatment, an r.f. treatment signal is applied between the r.f. treatment electrode (10) and the return electrode (40) for heating an inner region (15) of skin; an impedance measurement circuit (35) configured and arranged to measure, before treatment of the inner region, an initial skin impedance (Zo) between the r.f. treatment electrode (10) and the return electrode (40); and a treatment settings determiner (30) configured and arranged to determine, before treatment of the inner region (15), treatment settings associated with the r.f. treatment signal depending on the initial skin impedance (Zo) and on a dimension of the r.f. treatment electrode (10) in the contact plane, the treatment settings comprising at least one of a treatment duration (TD) associated with a desired treatment result, and an r.f. electrical parameter associated with the r.f. treatment signal. The skin treatment device (100) further comprises a controller (25) configured and arranged to consecutively activate the impedance measurement circuit (35) and the treatment settings determiner (30) before treatment of the inner region (15), configure the r.f. generator (20) to provide the r.f. treatment signal according to the treatment settings, and activate the r.f. generator (20) to apply the r.f. treatment signal to the inner region (15) for the treatment duration (TD). The invention is based on the insight obtained from multiple measurements made during the creation of microscopic thermal lesions in an inner region of skin by applying r.f. measurement and treatment signals. By analyzing the histological and heating results, a relationship was obtained between the initial impedance (Zo), the dimension of the r.f. treatment electrode (10), and the treatment settings required to obtain a particular skin treatment result. This relationship has been found to be relatively constant for different subjects, different treatment locations on the body and different skin moisture contents. The invention makes it possible to preset or predetermine, i.e. in advance, the treatment duration (TD) and/or the r.f. electrical parameters associated with the r.f. treatment signal accurately enough to avoid undesired skin damage during the treatment. The device can be simpler, as it is no longer essential to continuously monitor the impedance during treatment to determine the onset of undesired skin damage, such as ablation, which is the safety feature known from conventional devices.
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