公开(公告)号：US20170045430A1

公开(公告)日：2017-02-16

申请号：US15216938

申请日：2016-07-22

Applicant: Korea Institute of Science and Technology

Inventor： Rhokyun KWAK ,  Ji Yoon KANG ,  Jaesung PARK ,  Siwoo CHO

IPC: G01N1/40 ,  G01N27/447 ,  C12Q1/68

CPC classification number: G01N1/40 ,  C12Q1/6806 ,  G01N2001/4038

Abstract: Provided are an extracellular vesicle collecting apparatus using an electrode and a porous membrane and a method for using the same. The extracellular vesicle collecting apparatus includes i) an upper frame in which a pair of through holes is disposed so that a buffer solution flows therethrough, ii) a buffer tube which is inserted in the through holes and in which the buffer solution flows, iii) a positive electrode disposed on the upper frame, iv) a porous membrane located below the upper frame, v) a spacer which is located below the porous membrane and has a hollow space disposed therein, vi) a plurality of guide tubes through which a blood flows in the hollow space, vii) a lower frame which is coupled to the upper frame to be opposite to the upper frame and receives the porous membrane and the spacer therein, and viii) a negative electrode provided below the lower frame. Extracellular vesicles contained in the blood are collected by the porous membrane.

Abstract translation: 提供使用电极和多孔膜的细胞外小泡收集装置及其使用方法。 细胞外囊泡收集装置包括：i）上部框架，其中设置一对通孔，使得缓冲溶液流过其中; ii）缓冲管，其插入通孔中，缓冲溶液流动; iii） 设置在上框架上的正电极，iv）位于上框架下方的多孔膜，v）位于多孔膜下方并具有设置在其中的中空空间的间隔件，vi）多个导管，血液 在中空空间中流动，vii）下框架，其联接到上框架以与上框架相对并且在其中容纳多孔膜和间隔件，以及viii）设置在下框架下方的负极。 通过多孔膜收集血液中所含的细胞外囊泡。

公开(公告)号：US20230019206A1

公开(公告)日：2023-01-19

申请号：US17465977

申请日：2021-09-03

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  IUCF-HYU (Industry-University Cooperation Foundation Hanyang University)

Inventor： Hyunjung YI ,  Wonseop HWANG ,  Seongjin PARK ,  Rhokyun KWAK ,  Jina CHOI ,  Sangha KIM

IPC: A61B5/0533 ,  A61B5/00 ,  A61B5/352 ,  A61B5/397

Abstract: A wearable device according to the present disclosure includes: a communication portion; a body fluid sensor configured to measure conductivity in body fluid; and a controller configured to control the communication portion to transmit conductivity data to an external device in response to the frequency of rapid change in the conductivity.

公开(公告)号：US20230013756A1

公开(公告)日：2023-01-19

申请号：US17471165

申请日：2021-09-10

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  IUCF-HYU (Industry-University Cooperation Foundation Hanyang University)

Inventor： Rhokyun KWAK ,  Jina CHOI ,  Sangha KIM ,  Hyunjung YI ,  Seongjin PARK

IPC: A61B5/145 ,  A61B5/1477 ,  A61B5/00 ,  A61B10/00

Abstract: A sweat sensor patch of the present disclosure is a sweat sensor patch attached to a skin of a user and used, and includes: an opening formed layer which has a first surface and a second surface which face in opposite directions, and includes an opening penetrating in a thickness direction from the first surface to the second surface; an electrode layer formed on an inner wall surface of the opening; a porous layer which is stacked on the second surface of the opening formed layer and is formed to cover the opening; and a porous pillar which extends in the thickness direction of the opening formed layer within the opening and is connected with the porous layer.

公开(公告)号：US20200205673A1

公开(公告)日：2020-07-02

申请号：US16691006

申请日：2019-11-21

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hyunjung YI ,  Tae-Hyung KANG ,  Sunho KIM ,  In-Suk CHOI ,  Rhokyun KWAK ,  Sangha KIM ,  Jina CHOI

IPC: A61B5/024 ,  A61B5/00

Abstract: Provided is a sensor patch configured to be attached to the skin of a user. The sensor patch may include: at least one opening; and a frame surrounding the at least one opening, wherein the frame may include at least one senor configured to measure a biosignal of the user. Therefore, since the at least one sensor for measuring a biosignal is provided on the frame surrounding at least one opening, it may be possible to continuously obtain a biosignal of the user for a long period of time.

公开(公告)号：US20150253313A1

公开(公告)日：2015-09-10

申请号：US14575129

申请日：2014-12-18

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Kyoseon HWANG ,  Tae Song KIM ,  Rhokyun KWAK ,  Won Woo CHO ,  Myung Sic CHAE

IPC: G01N33/53

CPC classification number: G01N33/5302 ,  G01N29/022 ,  G01N29/036 ,  G01N33/54373 ,  G01N33/5438 ,  G01N2291/0427

Abstract: The present disclosure relates to a cantilever sensor, and a biosensor having the same, wherein the cantilever sensor including a slit formed on a flat board and a cantilever formed by the slit, a first electrode formed on the cantilever, and a second electrode formed on the flat board countered to the first electrode about the slit, wherein the electrodes are formed on the cantilever sensor having the slit, whereby sensing can be conducted by an electric method, through which the sensor can be effectively miniaturized.

Abstract translation: 本发明涉及一种悬臂传感器及具有该悬臂传感器的生物传感器，其中，悬臂传感器包括形成在平板上的狭缝和由狭缝形成的悬臂，形成在悬臂上的第一电极和形成在悬臂上的第二电极 扁平板围绕狭缝对抗第一电极，其中电极形成在具有狭缝的悬臂传感器上，由此可以通过电气方法进行感测，通过该方法可以有效地使传感器小型化。