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公开(公告)号：US20230000920A1
公开(公告)日：2023-01-05
申请号：US17780391
申请日：2020-11-27
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , HB ADVISORS
Inventor： Sun Hwa KIM , Yoosoo YANG , Hyo Suk KIM , Gi-Jung KWAK , Ye Ji JANG
Abstract: The present invention relates to a novel use of milk exosomes, and more specifically, provides various uses of milk exosomes, such as in functional cosmetics, functional health food with various functions such as improving gut health and immunity, and drugs including a wound healing medication.
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Patent Agency Ranking
公开(公告)号：US20210015931A1
公开(公告)日：2021-01-21
申请号：US16573351
申请日：2019-09-17
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Sun Hwa KIM , Ick Chan KWON , In-San KIM , Kwangmeyung KIM , Yoosoo YANG , Young-Ji KO
IPC: A61K47/55 , A61K47/54 , A61K31/713 , A61P35/00 , C12N15/113 , C07K14/705
Abstract: A fusion protein-siRNA complex according to the present disclosure binds specifically to cancer cells, is taken up effectively by the cells, and exhibits anticancer activity as it is degraded by lysosomes. The fusion protein-siRNA complex provides maximized anticancer activity so that the cancer cells can be removed by autoimmunity, by inhibiting the immunity of the cancer cells and enhancing phagocytosis by macrophages.
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公开(公告)号：US20200002677A1
公开(公告)日：2020-01-02
申请号：US16456127
申请日：2019-06-28
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Ick Chan KWON , Sun Hwa KIM , Yoosoo YANG , Hyosuk KIM
IPC: C12N5/077
Abstract: The present invention relates to a method for inducing trans-differentiation of cardiomyocytes based on exosome, and more particularly, to a method for inducing trans-differentiation of a fibroblast into a cardiomyocyte, comprising the steps of: isolating exosomes in a culture medium during a process of differentiating a stem cell into the cardiomyocyte; culturing a fibroblast in a cardiomyocyte reprogramming medium containing the isolated exosomes; and culturing the fibroblast cultured in a cardiomyocyte differentiation medium containing the isolated exosomes.
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公开(公告)号：US20230338425A1
公开(公告)日：2023-10-26
申请号：US18133886
申请日：2023-04-12
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHOLOGY , HB Advisors
Inventor： Sun Hwa KIM , Yoosoo YANG , Hyo Suk KIM , Gi-Jung KWAK , Ye Ji JANG
CPC classification number: A61K35/20 , A23L33/10 , A61K8/98 , A61Q5/02 , A61Q7/00 , A61Q19/02 , A61Q19/08
Abstract: The present invention relates to a novel use of milk exosomes, and more specifically, provides a method of enhancing immunity of a subject including administering a therapeutically effective amount of exosomes isolated from milk or goat milk to the subject.
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公开(公告)号：US20230338426A1
公开(公告)日：2023-10-26
申请号：US18133901
申请日：2023-04-12
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHOLOGY , HB Advisors
Inventor： Sun Hwa KIM , Yoosoo YANG , Hyo Suk KIM , Gi-Jung KWAK , Ye Ji JANG
CPC classification number: A61K35/20 , A23L33/10 , A61K8/98 , A61Q5/02 , A61Q7/00 , A61Q19/02 , A61Q19/08
Abstract: The present invention relates to a novel use of milk exosomes, and more specifically, provides a method of preventing or treating hair loss of a subject, the method including administering a therapeutically effective amount of exosomes isolated from milk or goat milk to the subject.
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公开(公告)号：US20230321149A1
公开(公告)日：2023-10-12
申请号：US18133918
申请日：2023-04-12
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHOLOGY , HB Advisors
Inventor： Sun Hwa KIM , Yoosoo YANG , Hyo Suk KIM , Gi-Jung KWAK , Ye Ji JANG
CPC classification number: A61K35/20 , A23L33/10 , A61K8/98 , A61Q5/02 , A61Q7/00 , A61Q19/02 , A61Q19/08
Abstract: The present invention relates to a novel use of milk exosomes, and more specifically, provides a method of inhibiting UV-induced oxidative damage of cells using an effective amount of exosomes isolated from milk or goat milk.
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