公开(公告)号：US20220296204A1

公开(公告)日：2022-09-22

申请号：US17601247

申请日：2020-04-02

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Eun-sun KIM ,  Seung-Jong KIM ,  Yongdoo PARK

IPC: A61B7/00 ,  A61B5/00 ,  A61B7/04 ,  G06F17/14

Abstract: A digestive canal scanning device of the present invention includes a sensor module, a data processing unit, and an analysis unit. A body scanning device of the present invention includes a sensor module, a data processing unit, and an analysis unit. An acoustic digestive organ monitoring system of the present invention includes an auscultation unit, an artifact collection unit, a signal extraction unit, a feature extraction unit, a database, an artificial neural network, and a wireless communication unit.

公开(公告)号：US20240159744A1

公开(公告)日：2024-05-16

申请号：US18041587

申请日：2021-08-12

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Ju Hee RYU ,  Ick Chan KWON ,  Kwangmeyung KIM ,  Han Young KIM ,  Eun-sun KIM

IPC: G01N33/542 ,  A61K47/64 ,  G01N33/574 ,  G01N33/68

CPC classification number: G01N33/542 ,  A61K47/642 ,  G01N33/57419 ,  G01N33/6893 ,  G01N2333/485

Abstract: The present disclosure relates to a cancer cell-specific complex for targeting cancer. The complex for targeting cancer according to the present disclosure includes EGF, but is affected more by lysosomal activity rather than the EGFR signaling pathway, and thus can overcome the shortcomings of the existing EGF therapy-based diagnostic and therapeutic compositions and provide successfully personalized and improved effects of treating, preventing and alleviating cancer.
A diagnostic composition according to the present disclosure enables the prediction of the anticancer performance of a therapeutic composition of the present disclosure in a subject, and thus enables anticancer treatment to be designed stably.

公开(公告)号：US20230333019A1

公开(公告)日：2023-10-19

申请号：US18115303

申请日：2023-02-28

Applicant: Korea University Research and Business Foundation ,  Daejin University Center for Educational Industrial Cooperation

Inventor： Seung Taek HONG ,  Eun-sun KIM ,  Bong Rae CHO ,  Mun Seok KIM

IPC: G01N21/64 ,  C07D263/57

CPC classification number: G01N21/6458 ,  G01N21/6428 ,  C07D263/57

Abstract: Disclosed are organelles-specific two-photon fluorescent probes, and more particularly, a blue emission two-photon fluorescent probe capable of selectively detecting calcium ions (Ca2+) through fluorescence signals by targeting the cytoplasm, mitochondria, and plasma membrane even among the organelles, respectively, and a green emission two-photon fluorescent probe capable of selectively detecting hydrogen ions (H+) through fluorescence signals by targeting the lysosome, a method for preparing these two-photon probes, and a method for separately or simultaneously imaging calcium ions in the cytoplasm, mitochondria, or plasma membrane and hydrogen ions in the lysosome using the two two-photon probes.

公开(公告)号：US20190183563A1

公开(公告)日：2019-06-20

申请号：US16310174

申请日：2017-06-14

Applicant: THE STANDARD CO., LTD. ,  KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Seong-Nam KIM ,  Hoon-Jai CHUN ,  Bora KEUM ,  Hyuk Soon CHOI ,  Jae Min LEE ,  Eun-sun KIM ,  Seung Han KIM

IPC: A61B18/14 ,  A61N1/32 ,  A61B1/04 ,  A61B1/07 ,  A61B5/053 ,  A61N1/04

CPC classification number: A61B18/14 ,  A61B1/018 ,  A61B1/04 ,  A61B1/07 ,  A61B5/053 ,  A61B18/00 ,  A61B18/12 ,  A61B18/1492 ,  A61B2018/00494 ,  A61B2018/00613 ,  A61B2018/00636 ,  A61B2018/00982 ,  A61B2018/143 ,  A61N1/0416 ,  A61N1/05 ,  A61N1/32

Abstract: The present invention relates to a therapeutic device which comprises: an endoscope channel; and an electrode that can be inserted into a human body through the endoscope channel, wherein the electrode destroys a target cell in the human body through voltage application, and the electrode includes a first optical fiber and a second optical fiber for detecting the degree of destruction of the target cell through impedance measurement. In addition, the present invention relates to a therapeutic device employing an endoscope-interworking electrode which comprises: an endoscope channel; and a catheter that can be inserted into a human body through the endoscope channel, wherein the catheter comprises a perforated portion provided on an end thereof, which is inserted into the human body, and a plurality of electrodes that can protrude from the end of the catheter through the perforated portion to penetrate a target cell.