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    Canine Amniotic Membrane-Derived Multipotent Stem Cells
    3.
    发明申请
    Canine Amniotic Membrane-Derived Multipotent Stem Cells 有权
    犬羊膜衍生多能干细胞

    公开(公告)号：US20140322182A1

    公开(公告)日：2014-10-30

    申请号：US14363145

    申请日：2012-12-06

    申请人： Kang Stem Biotech, Co., LTD.

    发明人： Kyung Sun Kang ,  Min Soo Seo ,  Sang Bum Park

    IPC分类号： C12N5/0735 ,  G01N33/569 ,  C12N5/079 ,  A61K35/50 ,  C12N5/077

    CPC分类号： C12N5/0606 ,  A61K35/50 ,  C12N5/0618 ,  C12N5/0653 ,  C12N5/0654 ,  C12N5/0655 ,  C12N5/0668 ,  G01N33/56966

    摘要： The present invention relates to canine amniotic membrane-derived multipotent stem cells (cAM-MSCs) and preparation method thereof. More particularly, the present invention relates to canine amniotic membrane-derived multipotent stem cells, which show negative immunological properties on human markers CD3, CD11c, CD28, CD34, CD38, CD41a, CD45, and CD62L and positive immunological properties on human markers CD90 and CD105, and have the ability to be maintained in an undifferentiated state for 20 passages or more and the ability to be differentiated into fat, bones, nerves, cartilage, etc.

    摘要翻译： 本发明涉及犬羊膜来源的多能干细胞（cAM-MSC）及其制备方法。 更具体地，本发明涉及犬羊膜衍生的多能干细胞，其对人标记物CD3，CD11c，CD28，CD34，CD38，CD41a，CD45和CD62L显示出阴性免疫学特性，并且对人标记物CD90和 CD105，具有维持在未分化状态20代以上的能力，能够分化为脂肪，骨骼，神经，软骨等。

    Equine Amniotic Membrane-Derived Mesenchymal Stem Cells
    4.
    发明申请
    Equine Amniotic Membrane-Derived Mesenchymal Stem Cells 有权
    马羊膜衍生的间充质干细胞

    公开(公告)号：US20140335060A1

    公开(公告)日：2014-11-13

    申请号：US14359974

    申请日：2012-11-22

    申请人： Kang Stem Biotech, Co., LTD.

    发明人： Kyung Sun Kang ,  Min Soo Seo ,  Sang Bum Park

    IPC分类号： C12N5/074

    CPC分类号： C12N5/0607 ,  A61K35/50 ,  C12N5/0668 ,  C12N2500/24 ,  C12N2500/32 ,  C12N2500/34 ,  C12N2500/38 ,  C12N2501/00 ,  C12N2501/33 ,  C12N2506/03

    摘要： The present invention relates to equine amniotic membrane-derived mesenchymal stem cells (eAM-MSCs) and a preparation method thereof. More specifically, the present invention relates to equine amniotic membrane-derived mesenchymal stem cells, which show negative immunological responses to all of the human markers CD19, CD20, CD28, CD31, CD34, CD38, CD41a, CD62L, CD62P and CD200, and positive immunological responses to all of the human markers CD44, CD90 and CD105, and have the ability to be maintained in an undifferentiated state for 14 passages or more and the ability to differentiate into ectoderm, mesoderm and endoderm-derived cells.

    摘要翻译： 本发明涉及马羊膜间充质干细胞（eAM-MSC）及其制备方法。 更具体地说，本发明涉及马氏羊膜间充质干细胞，其对所有人标记物CD19，CD20，CD28，CD31，CD34，CD38，CD41a，CD62L，CD62P和CD200显示阴性免疫应答，阳性 对所有人标记物CD44，CD90和CD105的免疫应答，并且具有维持在未分化状态14代或更多的能力以及分化成外胚层，中胚层和内胚层衍生细胞的能力。