公开(公告)号：US20140093564A1

公开(公告)日：2014-04-03

申请号：US14118071

申请日：2012-06-08

申请人： Kathryn Bradley ,  Richard Elkes ,  Shaun Fitzpatrick ,  Robert Saklatvala ,  Mustafa Mohamed ,  Richard Kendall

发明人： Kathryn Bradley ,  Richard Elkes ,  Shaun Fitzpatrick ,  Robert Saklatvala ,  Mustafa Mohamed ,  Richard Kendall

IPC分类号： A61K9/24 ,  A61K31/366 ,  A61K31/4985

CPC分类号： A61K9/209 ,  A61K9/2009 ,  A61K9/2018 ,  A61K9/2054 ,  A61K31/366 ,  A61K31/403 ,  A61K31/4196 ,  A61K31/4985 ,  A61K31/513 ,  A61K31/522 ,  A61K45/06 ,  A61K2300/00

摘要： The present invention is directed to novel pharmaceutical compositions comprising fixed dose combinations of a dipeptidyl peptidase-4 inhibitor (DPP-4 inhibitor), or a pharmaceutically acceptable salt thereof, and simvastatin, or pharmaceutically acceptable salt thereof, methods of preparing such pharmaceutical compositions, and methods of treating Type 2 diabetes and hypercholesterolemia with such pharmaceutical compositions. In particular, the invention is directed to pharmaceutical compositions comprising fixed-dose combinations of sitagliptin phosphate and simvastatin.

摘要翻译： 本发明涉及包含二肽基肽酶-4抑制剂（DPP-4抑制剂）或其药学上可接受的盐和辛伐他汀或其药学上可接受的盐的固定剂量组合的新型药物组合物，制备该药物组合物的方法， 以及用这种药物组合物治疗2型糖尿病和高胆固醇血症的方法。 特别地，本发明涉及包含西格列汀磷酸盐和辛伐他汀的固定剂量组合的药物组合物。

公开(公告)号：US20090123703A1

公开(公告)日：2009-05-14

申请号：US12298214

申请日：2007-02-06

申请人： Mustafa Mohamed

发明人： Mustafa Mohamed

IPC分类号： B32B27/28 ,  B01J31/18 ,  C08L83/04 ,  B05D3/02 ,  C08L83/05

CPC分类号： C08F4/52 ,  B01J31/146 ,  C08K5/55 ,  C08L83/04 ,  C08L83/10 ,  Y10T428/24479 ,  Y10T428/28 ,  Y10T428/31663 ,  C08L83/00

摘要： Borane catalyst complexes with amide functional polymers have a borane portion of the complex that may contain at least one silicon atom. The catalyst complexes can be used as components in curable compositions containing (i) the catalyst complex, (ii) a free radical polymerizable monomer, oligomer or polymer, and optionally (iii) a decomplexer. The curable compositions may contain a component capable of generating a gas, as well as various other optional ingredients. These curable compositions can be used as rubbers, tapes, adhesives, protective coatings, thin films, thermoplastic monolithic molded parts, thermosetting monolithic molded parts, sealants, foams, gaskets, seals, o-rings, pressure sensitive adhesives, die attachment adhesives, lid sealants, encapsulants, potting compounds, conformal coatings, and electronic components. The compositions can also be used in composite articles of manufacture in which substrates are coated or bonded together with the composition and cured, such as in connectors, diving masks, or other integrally bonded parts.

摘要翻译： 具有酰胺官能聚合物的硼烷催化剂络合物具有可含有至少一个硅原子的络合物的硼烷部分。 催化剂配合物可以用作可固化组合物中的组分，其中包含（i）催化剂络合物，（ii）可自由基聚合的单体，低聚物或聚合物，以及任选地（iii）还原剂。 可固化组合物可以含有能够产生气体的组分以及各种其它任选的成分。 这些可固化组合物可用作橡胶，胶带，粘合剂，保护涂层，薄膜，热塑性整体成型件，热固性整体成型件，密封剂，泡沫，垫圈，密封件，O型圈，压敏粘合剂，模具附着粘合剂，盖 密封剂，密封剂，灌封化合物，保形涂层和电子部件。 组合物也可以用于复合制品中，其中将基材与组合物一起涂布或粘合在一起并固化，例如在连接器，潜水掩模或其它整体结合的部件中。

公开(公告)号：US08198207B2

公开(公告)日：2012-06-12

申请号：US12298214

申请日：2007-02-06

申请人： Mustafa Mohamed

发明人： Mustafa Mohamed

IPC分类号： B32B27/28 ,  B01J31/18 ,  C08L83/04 ,  C08F4/52 ,  B01J27/02

CPC分类号： C08F4/52 ,  B01J31/146 ,  C08K5/55 ,  C08L83/04 ,  C08L83/10 ,  Y10T428/24479 ,  Y10T428/28 ,  Y10T428/31663 ,  C08L83/00

摘要： Borane catalyst complexes with amide functional polymers have a borane portion of the complex that may contain at least one silicon atom. The catalyst complexes can be used as components in curable compositions containing (i) the catalyst complex, (ii) a free radical polymerizable monomer, oligomer or polymer, and optionally (iii) a decomplexer. The curable compositions may contain a component capable of generating a gas, as well as various other optional ingredients. These curable compositions can be used as rubbers, tapes, adhesives, protective coatings, thin films, thermoplastic monolithic molded parts, thermosetting monolithic molded parts, sealants, foams, gaskets, seals, o-rings, pressure sensitive adhesives, die attachment adhesives, lid sealants, encapsulants, potting compounds, conformal coatings, and electronic components. The compositions can also be used in composite articles of manufacture in which substrates are coated or bonded together with the composition and cured, such as in connectors, diving masks, or other integrally bonded parts.

摘要翻译： 具有酰胺官能聚合物的硼烷催化剂络合物具有可含有至少一个硅原子的络合物的硼烷部分。 催化剂配合物可以用作可固化组合物中的组分，其中包含（i）催化剂络合物，（ii）可自由基聚合的单体，低聚物或聚合物，以及任选地（iii）还原剂。 可固化组合物可以含有能够产生气体的组分以及各种其它任选的成分。 这些可固化组合物可用作橡胶，胶带，粘合剂，保护涂层，薄膜，热塑性整体成型件，热固性整体成型件，密封剂，泡沫，垫圈，密封件，O形环，压敏粘合剂，模具附着粘合剂，盖 密封剂，密封剂，灌封化合物，保形涂层和电子部件。 组合物也可以用于复合制品中，其中将基材与组合物一起涂布或粘合在一起并固化，例如在连接器，潜水掩模或其它整体结合的部件中。

公开(公告)号：US08101702B2

公开(公告)日：2012-01-24

申请号：US12522593

申请日：2008-01-11

申请人： Mustafa Mohamed

发明人： Mustafa Mohamed

IPC分类号： C08G77/458

CPC分类号： C08G18/61 ,  C08G18/10 ,  C08G18/672 ,  C08G2170/40 ,  C09J175/04 ,  C09J175/16 ,  D01D5/0038 ,  D01F6/76

摘要： A silicone-containing composition comprises the reaction product of a first component and an excess of an isocyanate component relative to the first component to form an isocyanated intermediary. The first component is selected from one of a polysiloxane and a silicone resin. The first component includes a carbon-bonded functional group selected from one of a hydroxyl group and an amine group. The isocyanate component is reactive with the carbon-bonded functional group of the first component. The isocyanated intermediary includes a plurality of isocyanate functional groups. The silicone-containing composition comprises the further reaction product of a second component, which is selected from the other of the polysiloxane and the silicone resin. The second component includes a plurality of carbon-bonded functional groups reactive with the isocyanate functional groups of the isocyanated intermediary for preparing the silicone-containing composition.

摘要翻译： 含硅酮的组合物包含第一组分和过量的异氰酸酯组分相对于第一组分的反应产物以形成异氰酸酯化的中间体。 第一组分选自聚硅氧烷和硅树脂之一。 第一组分包括选自羟基和胺基之一的碳键合官能团。 异氰酸酯成分与第一成分的碳键合官能团反应。 异氰酸酯中间体包括多个异氰酸酯官能团。 含硅氧烷的组合物包含选自另一种聚硅氧烷和硅氧烷树脂的第二组分的另外的反应产物。 第二组分包括与用于制备含硅氧烷的组合物的异氰酸酯中间体的异氰酸酯官能团反应的多个与碳键合的官能团。

公开(公告)号：US20100127219A1

公开(公告)日：2010-05-27

申请号：US12522593

申请日：2008-01-11

申请人： Mustafa Mohamed

发明人： Mustafa Mohamed

IPC分类号： H01B1/20 ,  C08G18/00

CPC分类号： C08G18/61 ,  C08G18/10 ,  C08G18/672 ,  C08G2170/40 ,  C09J175/04 ,  C09J175/16 ,  D01D5/0038 ,  D01F6/76

摘要： A silicone-containing composition comprises the reaction product of a first component and an excess of an isocyanate component relative to the first component to form an isocyanated intermediary. The first component is selected from one of a polysiloxane and a silicone resin. The first component includes a carbon-bonded functional group selected from one of a hydroxyl group and an amine group. The isocyanate component is reactive with the carbon-bonded functional group of the first component. The isocyanated intermediary includes a plurality of isocyanate functional groups. The silicone-containing composition comprises the further reaction product of a second component, which is selected from the other of the polysiloxane and the silicone resin. The second component includes a plurality of carbon-bonded functional groups reactive with the isocyanate functional groups of the isocyanated intermediary for preparing the silicone-containing composition.

摘要翻译： 含硅酮的组合物包含第一组分和过量的异氰酸酯组分相对于第一组分的反应产物以形成异氰酸酯化的中间体。 第一组分选自聚硅氧烷和硅树脂之一。 第一组分包括选自羟基和胺基之一的碳键合官能团。 异氰酸酯成分与第一成分的碳键合官能团反应。 异氰酸酯中间体包括多个异氰酸酯官能团。 含硅氧烷的组合物包含选自另一种聚硅氧烷和硅氧烷树脂的第二组分的另外的反应产物。 第二组分包括与用于制备含硅氧烷的组合物的异氰酸酯中间体的异氰酸酯官能团反应的多个与碳键合的官能团。

公开(公告)号：US20080276983A1

公开(公告)日：2008-11-13

申请号：US12092150

申请日：2006-11-03

申请人： Robert Andrew Drake ,  Jean da la Croix Habimana ,  Nick Evan Shephard ,  Mustafa Mohamed ,  Barry Mark Ketola ,  James Steven Tonge ,  Stephen Jenkins ,  Stephen Altum

发明人： Robert Andrew Drake ,  Jean da la Croix Habimana ,  Nick Evan Shephard ,  Mustafa Mohamed ,  Barry Mark Ketola ,  James Steven Tonge ,  Stephen Jenkins ,  Stephen Altum

IPC分类号： H01L31/042

CPC分类号： H01L31/18 ,  C08L83/14 ,  H01L31/02167 ,  H01L31/0481 ,  Y02E10/50 ,  C08L2666/44

摘要： This invention relates to a photovoltaic cell module and a process of applying a silicone based hot melt encapsulant material (102a, 104a) onto photovoltaic cells (103a) to form a photovoltaic cell module. There is provided a photovoltaic array with more efficient manufacturing and better utilization of the solar spectrum by using silicone hot melt sheets (102a, 104a) to give a silicone encapsulant photovoltaic device with the process ease of an organic encapsulant but the optical and chemical advantages of a silicone encapsulant. There is further provided a method for fabricating photovoltaic cells with increased throughput and optical efficiency when compared to prior art encapsulation methods. The preferred silicone material is provided in flexible sheet with hot melt properties and low surface tack.

摘要翻译： 本发明涉及一种光伏电池模块以及将硅树脂热熔体密封材料（102a，104a）施加到光伏电池（103a）上以形成光伏电池模块的方法。 通过使用硅树脂热熔片（102a，104a）提供了更有效的制造和更好地利用太阳光谱的光伏阵列，以提供具有有机密封剂的方法的光学和化学方法的硅树脂密封剂光伏器件 硅胶密封剂的优点。 与现有技术的封装方法相比，还提供了一种具有增加的通量和光学效率的光伏电池的制造方法。 优选的硅氧烷材料以具有热熔性质和低表面粘性的柔性片材提供。