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公开(公告)号：US07956041B2
公开(公告)日：2011-06-07
申请号：US10972743
申请日：2004-10-26
申请人： Katsumi Maezono , Nozomu Ishida , Koji Ohsumi , Hiroyuki Matsueda , Toshihiro Hatanaka , Ryusuke Hirama , Yoko Kageyama , Nobuo Kondo
发明人： Katsumi Maezono , Nozomu Ishida , Koji Ohsumi , Hiroyuki Matsueda , Toshihiro Hatanaka , Ryusuke Hirama , Yoko Kageyama , Nobuo Kondo
CPC分类号： A61K31/426 , A61K31/155 , A61K31/175 , A61K31/197 , A61K31/4439 , A61K31/4453 , A61K31/64 , A61K31/7056 , A61K38/28 , A61K45/06 , A61K2300/00
摘要： The invention provides a prophylactic and therapeutic agent of diabetes mellitus, including a combination of an inhibitor of renal glucose reabsorption and a hypoglycemic agent. In accordance with the invention, hyperglycemia after meals, between meals and during fasting can be ameliorated. More specifically, in accordance with the invention, a therapeutic effect of diabetes mellitus as never been obtained by the hypoglycemic agents of the related art can be achieved.
摘要翻译： 本发明提供糖尿病的预防和治疗剂，包括肾葡萄糖再吸收抑制剂和降血糖药的组合。 根据本发明，可以改善膳食后，膳食间和禁食期间的高血糖。 更具体地，根据本发明，可以实现由相关领域的降血糖剂从未获得的糖尿病的治疗效果。
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公开(公告)号：US20050143424A1
公开(公告)日：2005-06-30
申请号：US10972743
申请日：2004-10-26
申请人： Katsumi Maezono , Nozomu Ishida , Koji Ohsumi , Hiroyuki Matsueda , Toshihiro Hatanaka , Ryusuke Hirama , Yoko Kageyama , Nobuo Kondo
发明人： Katsumi Maezono , Nozomu Ishida , Koji Ohsumi , Hiroyuki Matsueda , Toshihiro Hatanaka , Ryusuke Hirama , Yoko Kageyama , Nobuo Kondo
IPC分类号： A61K31/155 , A61K31/175 , A61K31/197 , A61K31/426 , A61K31/4439 , A61K31/4453 , A61K31/64 , A61K31/7056 , A61K38/28 , A61K45/06
CPC分类号： A61K31/426 , A61K31/155 , A61K31/175 , A61K31/197 , A61K31/4439 , A61K31/4453 , A61K31/64 , A61K31/7056 , A61K38/28 , A61K45/06 , A61K2300/00
摘要： The invention provides a prophylactic and therapeutic agent of diabetes mellitus, including a combination of an inhibitor of renal glucose reabsorption and a hypoglycemic agent. In accordance with the invention, hyperglycemia after meals, between meals and during fasting can be ameliorated. More specifically, in accordance with the invention, a therapeutic effect of diabetes mellitus as never been obtained by the hypoglycemic agents of the related art can be achieved.
摘要翻译： 本发明提供糖尿病的预防和治疗剂，包括肾葡萄糖再吸收抑制剂和降血糖药的组合。 根据本发明，可以改善膳食后，膳食间和禁食期间的高血糖。 更具体地，根据本发明，可以实现由相关领域的降血糖剂从未获得的糖尿病的治疗效果。
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3.发明授权N-substituted pyrazole-O-glycoside derivatives and therapeutic agent for diabetes containing the same 失效N-取代的吡唑-O-糖苷衍生物和含有其的治疗剂公开(公告)号：US06908905B2
公开(公告)日：2005-06-21
申请号：US10692738
申请日：2003-10-27
申请人： Koji Ohsumi , Hiroyuki Matsueda , Toshihiro Hatanaka , Nozomu Ishida , Yoko Kageyama , Katsumi Maezono , Nobuo Kondo
发明人： Koji Ohsumi , Hiroyuki Matsueda , Toshihiro Hatanaka , Nozomu Ishida , Yoko Kageyama , Katsumi Maezono , Nobuo Kondo
IPC分类号： A61P3/10 , C07H17/02 , A61K31/70 , A61K31/7028 , A61K31/7042
CPC分类号： C07H17/02 , Y10S514/866
摘要： The present invention relates to pyrazole derivatives represented by the following formulas and analogues thereof, which can be used for a therapeutic agent for diabetes.
摘要翻译： 本发明涉及可用于糖尿病治疗剂的由下式表示的吡唑衍生物及其类似物。
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公开(公告)号：US20060058244A1
公开(公告)日：2006-03-16
申请号：US11255937
申请日：2005-10-24
申请人： Koji Ohsumi , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
发明人： Koji Ohsumi , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
IPC分类号： A61K31/7052 , C07H17/02
CPC分类号： A61K31/7056 , C07H17/02 , Y10S514/866
摘要： The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine.
摘要翻译： 本发明提供用作糖尿病药的由下式表示的吡唑-O-糖苷衍生物。
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公开(公告)号：US20050043249A1
公开(公告)日：2005-02-24
申请号：US10936535
申请日：2004-09-09
申请人： Koji Ohsumi , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
发明人： Koji Ohsumi , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
IPC分类号： A61K31/7056 , A61P3/10 , C07H17/02 , C07H15/00 , A61K31/7052
CPC分类号： A61K31/7056 , C07H17/02 , Y10S514/866
摘要： The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine.
摘要翻译： 本发明提供用作糖尿病药的由下式表示的吡唑-O-糖苷衍生物。
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公开(公告)号：US20100063124A1
公开(公告)日：2010-03-11
申请号：US12621626
申请日：2009-11-19
申请人： Koji Ohsumi , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
发明人： Koji Ohsumi , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
IPC分类号： A61K31/4155 , C07D231/18 , A61P3/10
CPC分类号： A61K31/7056 , C07H17/02 , Y10S514/866
摘要： The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine.
摘要翻译： 本发明提供用作糖尿病药的由下式表示的吡唑-O-糖苷衍生物。
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公开(公告)号：US07645787B2
公开(公告)日：2010-01-12
申请号：US11774102
申请日：2007-07-06
申请人： Koji Ohsumi , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
发明人： Koji Ohsumi , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
IPC分类号： A61K31/4155 , A61P3/10 , C07D231/14
CPC分类号： A61K31/7056 , C07H17/02 , Y10S514/866
摘要： The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine.
摘要翻译： 本发明提供用作糖尿病药的由下式表示的吡唑-O-糖苷衍生物。
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公开(公告)号：US06815428B2
公开(公告)日：2004-11-09
申请号：US10427959
申请日：2003-05-02
申请人： Koji Ohsumi , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
发明人： Koji Ohsumi , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
IPC分类号： A61K3170
CPC分类号： A61K31/7056 , C07H17/02 , Y10S514/866
摘要： The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine.
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公开(公告)号：US07256209B2
公开(公告)日：2007-08-14
申请号：US11567039
申请日：2006-12-05
申请人： Koji Ohsumi , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
发明人： Koji Ohsumi , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
IPC分类号： A61K31/415 , C07D231/12
CPC分类号： A61K31/7056 , C07H17/02 , Y10S514/866
摘要： The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine
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公开(公告)号：US07247616B2
公开(公告)日：2007-07-24
申请号：US11255937
申请日：2005-10-24
申请人： Koji Ohsumi , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
发明人： Koji Ohsumi , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
IPC分类号： A61K31/70 , A61K31/7028 , A61K31/7042 , C07H17/02
CPC分类号： A61K31/7056 , C07H17/02 , Y10S514/866
摘要： The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine
摘要翻译： 本发明提供用作糖尿病药的由下式表示的吡唑-O-糖苷衍生物
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