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公开(公告)号:US20090041875A1
公开(公告)日:2009-02-12
申请号:US11918424
申请日:2006-04-12
申请人: Keiko Takada , Shinji Inomata , Yuki Ogura , Kenichi Umishio
发明人: Keiko Takada , Shinji Inomata , Yuki Ogura , Kenichi Umishio
摘要: There is provided a novel anti-wrinkle composition comprising one or more from among watercress, juniper, baizhu and coltsfoot extracts as active ingredients.
摘要翻译: 本发明提供了一种新颖的抗皱组合物,其包含以水田芥,杜松子,白芷和ts foot提取物中的一种或多种作为活性成分。
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公开(公告)号:US20090220627A1
公开(公告)日:2009-09-03
申请号:US12066876
申请日:2006-09-15
IPC分类号: A61K36/00
CPC分类号: A61Q19/08 , A61K8/97 , A61K36/05 , A61K36/185 , A61K36/28 , A61K36/8994 , A61K2300/00
摘要: The invention provides anti-aging agents, angiogenesis inhibitors and vascular endothelial growth factor (VEGF) expression inhibitors containing one or more galenicals selected from the group consisting of mukurossi peel extract, hazelnut extract, linden extract, coix extract, chlorella extract and tormentilla extract.
摘要翻译: 本发明提供含有一种或多种选自葫芦果皮提取物,榛子提取物,椴树提取物,ix ix提取物,小球藻提取物和折羊毒素提取物的抗衰老剂,血管生成抑制剂和血管内皮生长因子(VEGF)表达抑制剂。
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公开(公告)号:US20110171247A1
公开(公告)日:2011-07-14
申请号:US13064350
申请日:2011-03-21
IPC分类号: A61K36/185 , A61K8/97 , A61K36/77 , A61K36/8994 , A61K36/05 , A61K36/73 , A61Q19/08 , A61P9/00
CPC分类号: A61Q19/08 , A61K8/97 , A61K36/05 , A61K36/185 , A61K36/28 , A61K36/8994 , A61K2300/00
摘要: The invention provides anti-aging agents, angiogenesis inhibitors and vascular endothelial growth factor (VEGF) expression inhibitors containing one or more galenicals selected from the group consisting of mukurossi peel extract, hazelnut extract, linden extract, coix extract, chlorella extract and tormentilla extract.
摘要翻译: 本发明提供了含有一种或多种选自葫芦果皮提取物,榛子提取物,椴树提取物,ix ix提取物,小球藻提取物和折羊毒素提取物的抗衰老剂,血管生成抑制剂和血管内皮生长因子(VEGF)表达抑制剂。
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公开(公告)号:US20130006355A1
公开(公告)日:2013-01-03
申请号:US13582199
申请日:2011-01-19
CPC分类号: A61K31/4406 , A61F2/105 , A61K8/4926 , A61K8/4946 , A61K8/64 , A61K31/4184 , A61K38/005 , A61K38/07 , A61K2800/782 , A61L27/362 , A61L27/3804 , A61L27/3813 , A61L27/3886 , A61L27/60 , A61Q19/08
摘要: The present invention relates to a method for producing artificial skin, comprising: adding a matrix metalloproteinase inhibitor and a heparanase inhibitor to an artificial skin formation culture medium comprising human epidermal keratinocytes and human dermal fibroblasts, culturing the cells in the artificial skin formation culture medium, and forming artificial skin.
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公开(公告)号:US08871505B2
公开(公告)日:2014-10-28
申请号:US13582199
申请日:2011-01-19
CPC分类号: A61K31/4406 , A61F2/105 , A61K8/4926 , A61K8/4946 , A61K8/64 , A61K31/4184 , A61K38/005 , A61K38/07 , A61K2800/782 , A61L27/362 , A61L27/3804 , A61L27/3813 , A61L27/3886 , A61L27/60 , A61Q19/08
摘要: The present invention relates to a method for producing artificial skin, comprising: adding a matrix metalloproteinase inhibitor and a heparanase inhibitor to an artificial skin formation culture medium comprising human epidermal keratinocytes and human dermal fibroblasts, culturing the cells in the artificial skin formation culture medium, and forming artificial skin.
摘要翻译: 本发明涉及一种生产人造皮肤的方法,包括:将基质金属蛋白酶抑制剂和乙酰肝素酶抑制剂加入到人表皮角质形成细胞和人真皮成纤维细胞的人造皮肤形成培养基中,在人造皮肤形成培养基中培养细胞, 并形成人造皮肤。
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公开(公告)号:US20120328719A1
公开(公告)日:2012-12-27
申请号:US13582588
申请日:2011-01-21
IPC分类号: A61K36/38
CPC分类号: A61K45/06 , A61K8/4933 , A61K8/4946 , A61K31/416 , A61K31/4402 , A61K2800/782 , A61Q19/00 , A61K2300/00
摘要: An object of the present invention is to provide prevent or improve decreases in the barrier function and moisture retention function of the skin, and that object is achieved by applying an external preparation for skin that comprises a matrix metalloproteinase inhibitor and a heparanase inhibitor.
摘要翻译: 本发明的目的是提供防止或改善皮肤的屏障功能和保湿功能的降低,并且该目的通过应用包含基质金属蛋白酶抑制剂和乙酰肝素酶抑制剂的皮肤外用剂来实现。
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7.
公开(公告)号:US20120253064A1
公开(公告)日:2012-10-04
申请号:US13467254
申请日:2012-05-09
申请人: Mikiko Kaminuma , Masaru Suetsugu , Toshii Iida , Shinji Inomata , Keiko Takada , Yuji Katsuta
发明人: Mikiko Kaminuma , Masaru Suetsugu , Toshii Iida , Shinji Inomata , Keiko Takada , Yuji Katsuta
IPC分类号: C07C309/26
CPC分类号: A61K8/0212 , A61K8/44 , A61K8/466 , A61Q1/02 , A61Q19/00
摘要: To provide a parakeratosis inhibitor, pore reducing agent and skin roughness preventing/ameliorating agent that exhibit capabilities of parakeratosis inhibition, pore reduction, skin roughness prevention/amelioration, etc., and further provide a skin preparation for external use having these capabilities. There are provided a parakeratosis inhibitor, a pore reducing agent and a skin roughness preventing/ameliorating agent each comprising at least one compound selected from the group consisting of specified glycine derivatives and salts thereof and specified aminosulfuric acid derivatives and salts thereof. Still further, there are provided skin preparations for external use comprising these compounds.
摘要翻译: 提供表现角化不全抑制,减孔,皮肤粗糙度防止/改善等的角化不全抑制剂,减孔剂和皮肤粗糙度防止/改善剂,进一步提供具有这些能力的外用皮肤制剂。 提供了一种角化不全抑制剂,减孔剂和皮肤粗糙度防止/改善剂,其各自包含至少一种选自指定的甘氨酸衍生物及其盐的化合物和指定的氨基硫酸衍生物及其盐。 此外,提供了包含这些化合物的外用皮肤制剂。
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公开(公告)号:US20070225380A1
公开(公告)日:2007-09-27
申请号:US10580471
申请日:2004-11-22
申请人: Mikiko Kaminuma , Masaru Suetsugu , Toshii Iida , Shinji Inomata , Keiko Takada , Yuji Katsuta
发明人: Mikiko Kaminuma , Masaru Suetsugu , Toshii Iida , Shinji Inomata , Keiko Takada , Yuji Katsuta
IPC分类号: A61K47/12
CPC分类号: A61K8/0212 , A61K8/44 , A61K8/466 , A61Q1/02 , A61Q19/00
摘要: To provide a parakeratosis inhibitor, pore reducing agent and skin roughness preventing/ameliorating agent that exhibit capabilities of parakeratosis inhibition, pore reduction, skin roughness prevention/amelioration, etc., and further provide a skin preparation for external use having these capabilities. There are provide a parakeratosis inhibitor and a pore reducing agent each comprising at least one compound selected from the group consisting of a glycine derivative, an aminodicarboxylic acid derivative, an acylaminodicarboxylic acid derivative, a pyrrolidinecarboxylic acid derivative, a piperidinecarboxylic acid derivative, a hexamethyleneiminecarboxylic acid, a beta-alanine derivative and salts of these derivatives. Further, there are provided a parakeratosis inhibitor, a pore reducing agent and a skin roughness preventing/ameliorating agent each comprising at least one compound selected from the group consisting of specified glycine derivatives and salts thereof and specified aminosulfuric acid derivatives and salts thereof. Still further, there are provided skin preparations for external use comprising these compounds.
摘要翻译: 提供表现角化不全抑制,减孔,皮肤粗糙度防止/改善等的角化不全抑制剂,减孔剂和皮肤粗糙度防止/改善剂,进一步提供具有这些能力的外用皮肤制剂。 提供了角化不全抑制剂和孔还原剂,其各自包含至少一种选自甘氨酸衍生物,氨基二羧酸衍生物,酰氨基二羧酸衍生物,吡咯烷羧酸衍生物,哌啶羧酸衍生物,六亚甲基亚氨基羧酸 ,β-丙氨酸衍生物和这些衍生物的盐。 此外,提供了分别含有选自特定的甘氨酸衍生物及其盐的化合物和规定的氨基硫酸衍生物及其盐中的至少一种化合物的角化不全抑制剂,减孔剂和皮肤粗糙度防止改善剂。 此外,提供了包含这些化合物的外用皮肤制剂。
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9.
公开(公告)号:US20070134265A1
公开(公告)日:2007-06-14
申请号:US10588780
申请日:2004-05-18
申请人: Keiko Takada , Rikako Suzuki , Miki Guentert , Shinji Inomata , Chika Hamada , Takayuki Sakiguchi
发明人: Keiko Takada , Rikako Suzuki , Miki Guentert , Shinji Inomata , Chika Hamada , Takayuki Sakiguchi
IPC分类号: A61K36/06 , A61K31/737
摘要: There are provided an anti-aging composition, a collagen production promoting composition, a collagen gel contraction promoting composition, and an integrin production promoting composition for promoting integrin production in fibroblasts/epidermal cell, which have improved collagen production promotion effect and are effective for preventing or reducing wrinkle and/or sagging caused by aging. These anti-aging composition and promoting composition comprise, as an active ingredient, a hydrogen peroxide-treated yeast hydrolysate.
摘要翻译: 提供抗老化组合物,胶原蛋白生成促进组合物,胶原凝胶收缩促进组合物和用于促进成纤维细胞/表皮细胞中整联蛋白产生的整联蛋白生产促进组合物,其具有改善的胶原蛋白生产促进作用并且有效预防 或减少由老化引起的皱纹和/或松弛。 这些抗衰老组合物和促进组合物包含作为活性成分的过氧化氢处理的酵母水解物。
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公开(公告)号:US08586638B2
公开(公告)日:2013-11-19
申请号:US10580471
申请日:2004-11-22
申请人: Mikiko Kaminuma , Masaru Suetsugu , Toshii Iida , Shinji Inomata , Keiko Takada , Yuji Katsuta
发明人: Mikiko Kaminuma , Masaru Suetsugu , Toshii Iida , Shinji Inomata , Keiko Takada , Yuji Katsuta
IPC分类号: A61K47/12
CPC分类号: A61K8/0212 , A61K8/44 , A61K8/466 , A61Q1/02 , A61Q19/00
摘要: To provide a parakeratosis inhibitor, pore reducing agent and skin roughness preventing/ameliorating agent that exhibit capabilities of parakeratosis inhibition, pore reduction, skin roughness prevention/amelioration, etc., and further provide a skin preparation for external use having these capabilities. There are provide a parakeratosis inhibitor and a pore reducing agent each comprising at least one compound selected from the group consisting of a glycine derivative, an aminodicarboxylic acid derivative, an acylaminodicarboxylic acid derivative, a pyrrolidinecarboxylic acid derivative, a piperidinecarboxylic acid derivative, a hexamethyleneiminecarboxylic acid, a beta-alanine derivative and salts of these derivatives. Further, there are provided a parakeratosis inhibitor, a pore reducing agent and a skin roughness preventing/ameliorating agent each comprising at least one compound selected from the group consisting of specified glycine derivatives and salts thereof and specified aminosulfuric acid derivatives and salts thereof. Still further, there are provided skin preparations for external use comprising these compounds.
摘要翻译: 提供表现角化不全抑制,减孔,皮肤粗糙度防止/改善等的角化不全抑制剂,减孔剂和皮肤粗糙度防止/改善剂,进一步提供具有这些能力的外用皮肤制剂。 提供了角化不全抑制剂和孔还原剂,其各自包含至少一种选自甘氨酸衍生物,氨基二羧酸衍生物,酰氨基二羧酸衍生物,吡咯烷羧酸衍生物,哌啶羧酸衍生物,六亚甲基亚氨基羧酸 ,β-丙氨酸衍生物和这些衍生物的盐。 此外,提供了分别含有选自特定的甘氨酸衍生物及其盐的化合物和规定的氨基硫酸衍生物及其盐中的至少一种化合物的角化不全抑制剂,减孔剂和皮肤粗糙度防止改善剂。 此外,提供了包含这些化合物的外用皮肤制剂。
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