摘要:
The present invention provides a method for producing flavan derivatives having various substituent groups with controlling the stereochemistry. The method of the present invention includes the steps of: hydratively condensing a phenol compound expressed by formula (I) and an alcohol compound expressed by formula (II) to from an epoxide compound of formula (III); opening the epoxy ring of the epoxide compound of formula (III) to form an iodine-containing compound of formula (IV); and cyclizing the iodine-containing compound to form the flavan derivative of formula (V).
摘要:
A simple and easy process for preparing pharmacologically useful flavonoid compound having reductase inhibitory effect, active oxygen extinguishing effect, carcinogenesis promotion inhibitory effect, anti-inflammatory effect, and so on. Particularly, a process for preparing the compound of the formula (I): wherein, R2 is a substituted or un-substituted phenyl group; R7 is a hydrogen atom or a hydroxyl group; and n is an integer of 1 to 4; by bonding a sugar derivative to catechins as the starting compound selectively via O-glycoside bond and then oxidizing the 4-position of flavanoid skeleton of the obtained compound.
摘要翻译:制备具有还原酶抑制作用,活性氧灭活效果,致癌作用促进抑制作用,抗炎作用等药理学有用的类黄酮化合物的简单易用的方法。 特别是制备式(I)化合物的方法:其中R 2是取代或未取代的苯基; R 7是氢原子或羟基; n为1〜4的整数,通过O-糖苷键选择性地将糖衍生物与作为起始化合物的儿茶素类结合,然后氧化所得化合物的类黄酮骨架的4位。
摘要:
The present invention provides a method for producing flavan derivatives having various substituent groups with controlling the stereochemistry. The method of the present invention includes the steps of: hydratively condensing a phenol compound expressed by formula (I) and an alcohol compound expressed by formula (II) to from an epoxide compound of formula (III); opening the epoxy ring of the epoxide compound of formula (III) to form an iodine-containing compound of formula (IV); and cyclizing the iodine-containing compound to form the flavan derivative of formula (V).
摘要:
In the medical cap comprising a plug 10 made of thermoplastic elastomer and an outer frame 20 made of synthetic resin, the side surface part of the plug is contacted with an inner wall 211 of the side circuit part of the outer frame in a non-fused state and is held in a state with pressure applied from the leg part of the outer frame 22. As a result, the wetted surface of the plug is not flat shaped but has an inclination downward to the circle center. Protrusion 14 can also be provided on the wetted surface and in such a case, the bottom part of the protrusion part that is one part of the wetted surface has an inclination downward to the circle center.
摘要:
Provided is a semiconductor device capable of preventing destruction of an electrode having a pillar shape and densely arranged. The semiconductor device having a field-effect transistor and a capacitor having a pillar shape, the semiconductor device includes: a first electrode having a pillar shape and electrically connected to an impurity diffusion region of the field-effect transistor; a dielectric film formed at least on a side of the first electrode; a second electrode formed on the dielectric film; and a support film extending in a direction crossing a length direction of the first electrode having the pillar shape, and formed by a boron-added silicon nitride film connected to the first electrode by penetrating through at least a part of the second electrode.
摘要:
The present invention provides the steps of: at a priority control node (PCRF), when reception of an invite signal including priority call information is notified from a call control node (P-CSCF), determining whether it is required to change the ARP of a call control signal bearer for sending the invite signal from a gateway (P-GW) to a mobile terminal (UE) to a higher ARP than the priority set in the call control signal bearer; when change of the ARP is determined to be required, changing the ARP of the call control signal bearer to a higher ARP than the ARP set in the call control signal bearer; and performing a paging for the mobile terminal (UE) according to the priority of the call control signal bearer.
摘要:
A mobile communication method according to the present invention comprising the subscriber management server device HSS determines either the radio access network of the WCDMA scheme or the radio access network of the LTE scheme as the standby radio access network of the mobile station UE based on the CSFB capability presence/absence information included in the received “Update GPRS Location/Update Location Request” of received the mobile station UE, and a step in which the mobile station UE performs the standby operation in the standby radio access network of the mobile station UE determined by the subscriber management server device HSS.
摘要:
A CSFB processing unit (14) of a mobile switching center (MME) of according to the present invention is configured not to perform CSFB processing to enable a mobile station (UE), which establishes a bearer in a core network of a mobile communication system of the LTE scheme, to start CS communication in a mobile communication system of the WCDMA scheme, when CS communication of the mobile station (UE) in the mobile communication system of the WCDMA scheme is restricted in a specified area, even when the mobile switching center (MME) of the mobile communication system of the LTE scheme detects that a service request signal transmitted by the mobile station contains the first identification information.
摘要:
A communication method according to the present invention includes: transmitting, at a radio base station device (b), broadcast information for notifying a first area and a second area; transmitting, from a first mobile terminal to a radio control device (c), a first location registration request signal for the first area included in the broadcast information, when the first area is not identical to a first area stored as a current location registration area; and transmitting, from a second mobile terminal to the radio control device (c), a second location registration request signal for the second area included in the broadcast information, when the second area is not included in a second area group stored as a current location registration area.
摘要:
A clip includes a first member engaging a first attached member, and a second member supported in the first member and engaging a second attached member. The clip connects both attached members, and when a load acts in a direction separating both attached members, the clip allows a separation of both attached members only for a predetermined distance. The first member includes a base portion engaging the first attached member, a protruding piece portion in the base portion, and an expanded head portion wider than the protruding piece portion formed in an end portion of the protruding piece portion. The second member includes a through hole through which the protruding piece portion loosely passes, and a cylinder portion supported in the protruding piece portion to be displaced in a protruding direction thereof, and also retained in the protruding piece portion by the base portion and the expanded head portion.