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公开(公告)号:US08778346B2
公开(公告)日:2014-07-15
申请号:US13287208
申请日:2011-11-02
申请人: Rachel Rebecca Barrett , Keith Canada , Katrina Mary Catron , Robert Copenhaver , Lee Edward Frego , Ernest Lee Raymond , Sanjaya Singh , Xiangyang Zhu
发明人: Rachel Rebecca Barrett , Keith Canada , Katrina Mary Catron , Robert Copenhaver , Lee Edward Frego , Ernest Lee Raymond , Sanjaya Singh , Xiangyang Zhu
IPC分类号: A61K39/395 , C07K16/46 , C07K16/24 , A61K39/00
CPC分类号: C07K16/244 , A61K2039/505 , C07K2317/24 , C07K2317/34 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C12N15/113
摘要: The present invention relates to anti-IL-23p19 binding compounds, in particular new humanized anti-IL-23p19 antibodies and therapeutic and diagnostic methods and compositions for using the same.
摘要翻译: 本发明涉及抗IL-23p19结合化合物,特别是新的人源化抗IL-23p19抗体以及用于其的治疗和诊断方法和组合物。
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公开(公告)号:US20120093814A1
公开(公告)日:2012-04-19
申请号:US13254887
申请日:2010-03-30
申请人: Keith Canada , Sanjaya Singh , Xiangyang Zhu
发明人: Keith Canada , Sanjaya Singh , Xiangyang Zhu
IPC分类号: A61K39/395 , A61P9/12 , A61P9/00 , C07K16/00 , C07H21/04
CPC分类号: C07K14/58 , C07K2317/20 , C07K2317/52 , C07K2319/30
摘要: The present invention relates to therapeutic peptides and proteins fused to a canine antibody Fc domain. Methods and compositions of using the same are described.
摘要翻译: 本发明涉及与犬抗体Fc结构域融合的治疗性肽和蛋白质。 描述了使用该方法和组合物的方法和组合物。
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公开(公告)号:US09441036B2
公开(公告)日:2016-09-13
申请号:US14302986
申请日:2014-06-12
申请人: Rachel Rebecca Barrett , Keith Canada , Katrina Mary Catron , Robert Copenhaver , Lee Edward Frego , Ernest Lee Raymond , Sanjaya Singh , Xiangyang Zhu
发明人: Rachel Rebecca Barrett , Keith Canada , Katrina Mary Catron , Robert Copenhaver , Lee Edward Frego , Ernest Lee Raymond , Sanjaya Singh , Xiangyang Zhu
IPC分类号: C07K16/24 , C12N15/113 , C12N15/24 , A61K39/395 , A61K39/00
CPC分类号: C07K16/244 , A61K2039/505 , C07K2317/24 , C07K2317/34 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C12N15/113
摘要: The present invention relates to anti-IL-23p19 binding compounds, in particular new humanized anti-IL-23p19 antibodies and therapeutic and diagnostic methods and compositions for using the same.
摘要翻译: 本发明涉及抗IL-23p19结合化合物,特别是新的人源化抗IL-23p19抗体以及用于其的治疗和诊断方法和组合物。
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公开(公告)号:US20120282269A1
公开(公告)日:2012-11-08
申请号:US13287208
申请日:2011-11-02
申请人: Rachel Rebecca Barrett , Keith Canada , Katrina Mary Catron , Robert Copenhaver , Lee Edward Frego , Ernest Lee Raymond , Sanjaya Singh , Xiangyang Zhu
发明人: Rachel Rebecca Barrett , Keith Canada , Katrina Mary Catron , Robert Copenhaver , Lee Edward Frego , Ernest Lee Raymond , Sanjaya Singh , Xiangyang Zhu
IPC分类号: A61K39/395 , C07K16/46 , C12N15/13 , A61P35/00 , A61P29/00 , A61P37/06 , A61P3/00 , C07K16/24 , C12N5/071
CPC分类号: C07K16/244 , A61K2039/505 , C07K2317/24 , C07K2317/34 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C12N15/113
摘要: The present invention relates to anti-IL-23p19 binding compounds, in particular new humanized anti-IL-23p19 antibodies and therapeutic and diagnostic methods and compositions for using the same.
摘要翻译: 本发明涉及抗IL-23p19结合化合物,特别是新的人源化抗IL-23p19抗体以及用于其的治疗和诊断方法和组合物。
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公开(公告)号:US09090696B2
公开(公告)日:2015-07-28
申请号:US14046121
申请日:2013-10-04
申请人: Rachel Rebecca Barrett , Scott Ronald Brodeur , Keith Canada , Tobias Litzenburger , Sanjaya Singh
发明人: Rachel Rebecca Barrett , Scott Ronald Brodeur , Keith Canada , Tobias Litzenburger , Sanjaya Singh
CPC分类号: C07K16/2878 , A61K9/0019 , A61K2039/505 , C07K1/22 , C07K2317/24 , C07K2317/33 , C07K2317/51 , C07K2317/515 , C07K2317/53 , C07K2317/565 , C07K2317/71 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要: The present invention relates to new humanized antagonistic anti-CD40 antibodies and therapeutic and diagnostic methods and compositions for using the same.
摘要翻译: 本发明涉及新的人源化拮抗性抗CD40抗体及其使用的治疗和诊断方法及组合物。
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6.Methods of using antibodies during anticoagulant therapy of dabigatran and/or related compounds 有权
标题翻译: 在达比加群和/或相关化合物的抗凝治疗期间使用抗体的方法公开(公告)号:US09034822B2
公开(公告)日:2015-05-19
申请号:US13916994
申请日:2013-06-13
申请人: Joanne Van Ryn , John Edward Park , Norbert Hauel , Ulrich Kunz , Tobias Litzenburger , Keith Canada , Sanjaya Singh , Alisa Waterman
发明人: Joanne Van Ryn , John Edward Park , Norbert Hauel , Ulrich Kunz , Tobias Litzenburger , Keith Canada , Sanjaya Singh , Alisa Waterman
IPC分类号: A61K39/395 , C07K16/44
CPC分类号: C07K16/44 , A61K31/4439 , A61K39/39583 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/569 , C07K2317/622 , C07K2317/626 , C07K2317/76 , G01N33/86 , G01N2500/02 , G01N2500/10
摘要: The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants.
摘要翻译: 本发明涉及针对抗凝剂,特别是达比加群的抗体分子,以及它们作为这种抗凝剂的解毒剂的用途。
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7.Anticoagulant antidotes comprising antibodies that bind dabigatran and/or related compounds 有权
标题翻译: 抗凝血剂解毒剂,其包含结合达比加群和/或相关化合物的抗体公开(公告)号:US08486398B2
公开(公告)日:2013-07-16
申请号:US13010403
申请日:2011-01-20
申请人: Joanne Van Ryn , John Edward Park , Norbert Hauel , Ulrich Kunz , Tobias Litzenburger , Keith Canada , Sanjaya Singh , Alisa Waterman
发明人: Joanne Van Ryn , John Edward Park , Norbert Hauel , Ulrich Kunz , Tobias Litzenburger , Keith Canada , Sanjaya Singh , Alisa Waterman
IPC分类号: A61K39/395
CPC分类号: C07K16/44 , A61K31/4439 , A61K39/39583 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/569 , C07K2317/622 , C07K2317/626 , C07K2317/76 , G01N33/86 , G01N2500/02 , G01N2500/10
摘要: The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants.
摘要翻译: 本发明涉及针对抗凝剂,特别是达比加群的抗体分子,以及它们作为这种抗凝剂的解毒剂的用途。
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公开(公告)号:US20120027780A1
公开(公告)日:2012-02-02
申请号:US13010403
申请日:2011-01-20
申请人: Joanne Van Ryn , John Edward Park , Norbert Hauel , Ulrich Kunz , Tobias Litzenburger , Keith Canada , Sanjaya Singh , Alisa Waterman
发明人: Joanne Van Ryn , John Edward Park , Norbert Hauel , Ulrich Kunz , Tobias Litzenburger , Keith Canada , Sanjaya Singh , Alisa Waterman
IPC分类号: A61K39/395 , A61P7/04 , C12P21/00 , C07K16/00
CPC分类号: C07K16/44 , A61K31/4439 , A61K39/39583 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/569 , C07K2317/622 , C07K2317/626 , C07K2317/76 , G01N33/86 , G01N2500/02 , G01N2500/10
摘要: The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants.
摘要翻译: 本发明涉及针对抗凝剂的抗体分子,特别是达比加群,以及它们作为这种抗凝剂的解毒剂的用途。
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公开(公告)号:US08591900B2
公开(公告)日:2013-11-26
申请号:US13075303
申请日:2011-03-30
申请人: Rachel Rebecca Barrett , Scott Ronald Brodeur , Keith Canada , Tobias Litzenburger , Sanjaya Singh
发明人: Rachel Rebecca Barrett , Scott Ronald Brodeur , Keith Canada , Tobias Litzenburger , Sanjaya Singh
IPC分类号: A61K39/395 , C07K16/28
CPC分类号: C07K16/2878 , A61K9/0019 , A61K2039/505 , C07K1/22 , C07K2317/24 , C07K2317/33 , C07K2317/51 , C07K2317/515 , C07K2317/53 , C07K2317/565 , C07K2317/71 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要: The present invention relates to new humanized antagonistic anti-CD40 antibodies and therapeutic and diagnostic methods and compositions for using the same.
摘要翻译: 本发明涉及新的人源化拮抗性抗CD40抗体及其使用的治疗和诊断方法及组合物。
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10.Anticoagulant antidotes comprising antibodies that bind dabigatran and/or related compounds and methods of use thereof 有权
标题翻译: 抗凝血剂解毒剂,其包含结合达比加群和/或相关化合物的抗体及其使用方法公开(公告)号:US08821871B2
公开(公告)日:2014-09-02
申请号:US13432296
申请日:2012-03-28
申请人: Joanne Van Ryn , Keith Canada , Robert Copenhaver , Norbert Hauel , Tobias Litzenburger , Christopher Ronald Sarko , Sanjaya Singh , Alisa K. Waterman
发明人: Joanne Van Ryn , Keith Canada , Robert Copenhaver , Norbert Hauel , Tobias Litzenburger , Christopher Ronald Sarko , Sanjaya Singh , Alisa K. Waterman
IPC分类号: A61K39/395 , C07K16/44
CPC分类号: C07K16/44 , A61K31/4439 , A61K39/395 , A61K39/39583 , A61K2039/505 , C07K2299/00 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , A61K2300/00
摘要: The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants.
摘要翻译: 本发明涉及针对抗凝剂,特别是达比加群的抗体分子,以及它们作为这种抗凝剂的解毒剂的用途。
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