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公开(公告)号：US07523026B2
公开(公告)日：2009-04-21
申请号：US10454490
申请日：2003-06-05
IPC分类号： G06G7/48
CPC分类号： G01N33/6848 , G01N33/6818 , G06F19/16
摘要： A proteome analysis method includes using a tandem type mass spectrometer to calculate bond dissociation energy by using molecular simulation, using the bond dissociation energy to obtain prediction information including a cleavage pattern of a peptide and/or peak positions in a mass spectrum and/or the intensity ratio of the mass spectrum, and identifying a protein by using the prediction information and experiment information.
摘要翻译： 蛋白质组分析方法包括使用串联型质谱仪通过使用分子模拟来计算键解离能，使用键离解能获得包括肽的切割模式和/或质谱中的峰位置的预测信息和/或 质谱强度比，通过使用预测信息和实验信息鉴定蛋白质。
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公开(公告)号：US06226544B1
公开(公告)日：2001-05-01
申请号：US09096368
申请日：1998-06-12
IPC分类号： A61B505
CPC分类号： G06K9/0057 , A61B5/0476 , A61B5/7264
摘要： Obtaining fast dipole size estimation with less influence of noise by using a regional dipole model. An artificial neural network section 30 executes regional dipole size estimation using a neural network having coupling coefficients representing coupling states among as plurality of units and thresholds thereof.
摘要翻译： 通过使用区域偶极子模型获得噪声影响较小的快速偶极子尺寸估计。 人造神经网络部分30使用具有表示多个单元及其阈值之间的耦合状态的耦合系数的神经网络来执行区域偶极大小估计。
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公开(公告)号：US5638825A
公开(公告)日：1997-06-17
申请号：US426724
申请日：1995-04-21
IPC分类号： A61B5/0476 , A61B5/0484 , A61B5/04
CPC分类号： A61B5/0484
摘要： An evoked potential measuring apparatus by which an evoked potential which reflects a variation in internal condition of a human being such as a feeling of strain, a feeling of irritation or a feeling of stress can be measured in a high quality with a high degree of reliability. The apparatus comprises a sensory stimulus application section, an evoked potential measurement section for measuring and amplifying an evoked brain potential, an evoked potential recording control section for controlling recording of a brain potential signal, an evoked potential recording section for recording the brain potential signal, an internal condition estimating physiological measure measurement section for measuring a physiological measure, a physiological measure signal recording control section for controlling recording of a physiological measure signal, a physiological measure signal recording section for recording the physiological measure signal, an internal condition estimation section for estimating the internal condition of the subject using the physiological measure signal, an evoked potential adding and averaging section for adding and averaging the brain potential signal in accordance with the internal condition of the subject to obtain an evoked potential, an evoked potential adoption determination section for estimating a quality of the evoked potential to determine whether or not the evoked potential may be adopted, and an evoked potential measurement procedure control section.
摘要翻译： 诱发电位测定装置能够高度可靠地测量反映人的内部状态变化的诱发电位，例如应变感，刺激感或应激感， 。 该装置包括感觉刺激应用部分，用于测量和放大诱发脑电位的诱发电位测量部分，用于控制脑电位信号记录的诱发电位记录控制部分，用于记录脑电位信号的诱发电位记录部分， 用于测量生理测量的内部状态估计生理测量测量部分，用于控制生理测量信号的记录的生理测量信号记录控制部分，用于记录生理测量信号的生理测量信号记录部分，用于估计生理测量信号的内部条件估计部分 使用生理测量信号的受试者的内部状况，根据受试者的内部条件对脑电位信号进行加和平均的诱发电位加法和平均部分以获得诱发电位， 用于估计诱发电位的质量以确定是否可以采用诱发电位的电位采用确定部分和诱发电位测量程序控制部分。
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4.发明授权公开(公告)号：US07384790B2
公开(公告)日：2008-06-10
申请号：US10489198
申请日：2003-03-24
申请人： Kenji Miyazaki , Akira Tsugita , Naoyuki Takahashi , Takuji Nabetani , Toshimasa Yamazaki , Kenichi Kamijo
发明人： Kenji Miyazaki , Akira Tsugita , Naoyuki Takahashi , Takuji Nabetani , Toshimasa Yamazaki , Kenichi Kamijo
IPC分类号： G01N33/68 , G01N33/483 , G01N27/12
CPC分类号： G01N33/6821 , G01N33/6842
摘要： The present invention provides a method for analyzing the C-terminal amino acid sequence of a peptide by applying reaction technique for successively releasing the C-terminal amino acids therefrom, which method can suppress, when releasing the C-terminal amino acids of the peptide in sequence, such as an undesirable side reaction as cleavage of peptide bond in the intermediate position of the peptide, and allows to carry out the chemical treatment thereof under widely applicable conditions. In the method according to the present invention, an alkanoic acid anhydride and a perfluoroalkanoic acid both of vapor phase, which are supplied from a mixture containing an alkanoic acid anhydride with a small amount of a perfluoroalkanoic acid added thereto, are allowed to act on a dry sample of the peptide to be examined in a dry atmosphere at a temperature chosen in a range of 15 to 60° C.; whereby the release of the C-terminal amino acid is resulted from successive formation of a 5-oxazolone structure being followed by cleavage of the 5-oxazolone ring; and then the C-terminal amino acids sequence is identified by analysis based on the decrease in molecular weight in a series of the reaction products obtained.
摘要翻译： 本发明提供了通过应用从其中连续释放C末端氨基酸的反应技术来分析肽的C末端氨基酸序列的方法，当释放肽的C末端氨基酸时，该方法可以抑制 序列，例如作为在肽的中间位置处的肽键的切割的不期望的副反应，并且允许在广泛适用的条件下进行其化学处理。 在根据本发明的方法中，允许从含有链烷酸酐和少量全氟链烷酸的混合物中提供的气相的链烷酸酐和全氟烷酸作用于 在干燥气氛中在15至60℃范围内选择的温度下待检测的肽的干样品; 由此C末端氨基酸的释放是由连续形成5-恶唑酮结构而引起的，随后是5-恶唑酮环的裂解; 然后通过基于所获得的一系列反应产物中分子量的降低的分析来鉴定C-末端氨基酸序列。
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公开(公告)号：US5179956A
公开(公告)日：1993-01-19
申请号：US721317
申请日：1991-06-26
申请人： Chikao Harada , Norio Kawamura , Ryuji Nakashima , Arihiro Takahashi , Toshimasa Yamazaki , Masanobu Yasui , Tatsushi Kondo
发明人： Chikao Harada , Norio Kawamura , Ryuji Nakashima , Arihiro Takahashi , Toshimasa Yamazaki , Masanobu Yasui , Tatsushi Kondo
IPC分类号： A61B5/022
CPC分类号： A61B5/02233 , Y10S73/04
摘要： A contact pressure sensor including a semiconductor chip having opposite surfaces, at least one pressure sensing element provided in one of the opposite surfaces of the chip, a spacer member supporting the other surface of the chip, a substrate having a surface to which the spacer member is fixed, the one surface of the chip being pressed against an object which produces a pressure, so that the at least one sensing element detects the pressure produced by the object, a first connection terminal provided in the one surface of the chip, a second connection terminal provided in the surface of the substrate, and a flexible flat cable connecting between the first and second connection terminals, the flexible flat cable being bent into two portions one of which extends along a side surface of the spacer member and the other of which extends along the surface of the substrate. The contact pressure sensor may further comprise a light-shading layer covering the one surface of the chip in which the at least one pressure sensing element is provided.
摘要翻译： 一种接触压力传感器，包括具有相反表面的半导体芯片，设置在芯片的相对表面之一中的至少一个压力感测元件，支撑芯片的另一个表面的间隔件，具有表面的基板，间隔件 被固定，芯片的一个表面被压在产生压力的物体上，使得至少一个感测元件检测由物体产生的压力，设置在芯片的一个表面中的第一连接端子，第二 连接端子，以及连接在第一和第二连接端子之间的柔性扁平电缆，柔性扁平电缆被弯曲成两个部分，其中一个沿着间隔件的侧表面延伸，另一个 沿着衬底的表面延伸。 接触压力传感器还可以包括覆盖芯片的一个表面的遮光层，其中提供至少一个压力感测元件。
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公开(公告)号：US5062318A
公开(公告)日：1991-11-05
申请号：US617810
申请日：1990-11-26
申请人： Toshimasa Yamazaki
发明人： Toshimasa Yamazaki
CPC分类号： B62M9/105 , B62M9/00 , Y10T74/2164 , Y10T74/2165
摘要： A bicycle gear crank assembly includes a crank having a boss portion fittable to a crank shaft, and a chainwheel mounted on the crank boss portion. The chainwheel includes a largest sprocket and at least one smaller sprocket coaxial with the largest sprocket. The crank boss portion is provided with backup arms located on the side of the largest sprocket laterally away from the smaller sprocket. The backup arms extend radially outward from the crank boss portion to contact the largest sprocket radially outwardly of the crank boss portion, so that the backup arms prevent the largest sprocket from laterally bending in a direction away from the smaller sprocket.
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公开(公告)号：US4901595A
公开(公告)日：1990-02-20
申请号：US86865
申请日：1987-08-19
申请人： Nobuo Ozaki , Kazuyuki Miura , Toshimasa Yamazaki
发明人： Nobuo Ozaki , Kazuyuki Miura , Toshimasa Yamazaki
CPC分类号： B62L3/02 , Y10T74/20213 , Y10T74/20287 , Y10T74/2042 , Y10T74/20438 , Y10T74/20822 , Y10T74/2087
摘要： A bicycle auxiliary brake control assembly which is provided on a bicycle body in a path of a double type control cable extending from a brake lever assembly to a brake assembly and including an outer cable and an inner cable, the outer cable being divided into two separate sections each having a divided end, wherein the auxiliary brake control assembly comprises a fixed member engaging with the divided end of one section of the outer cable at a fixed position, and an operating member engaging with the divided end of the other section of the outer cable and movable to enlarge and reduce the distance between the divided ends of the respective sections of the outer cable.
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公开(公告)号：US20060175680A1
公开(公告)日：2006-08-10
申请号：US10549672
申请日：2003-03-19
IPC分类号： H01L29/00
CPC分类号： H01P5/10
摘要： A balun in which the phase shift may be reduced significantly is disclosed. The balun has three lines, i.e. a first line b, a second line a and a third line c, arranged in parallel with the ground surface. The second line a and the third line c are arranged at the same height from the ground surface GC, the longitudinal length of each respective one of the first line b, second line a and third line c are specified to be equal to a quarter (¼) of the wavelength at the central frequency in the working band, and the capacitance Ca between the second line a and the ground surface GC is specified to be equal to the capacitance Cab between the second line a and the first line b. Furthermore, the distance h3 between the center of each respective one of the second line a and third line c in the height direction and the ground surface GC located closer to each respective one of the second line a and third line c is specified to be longer than the distance h2 between the center of the first line b in the height direction and the center of each respective one of the second line a and third line c in the height direction, or the permittivity of a dielectric D3 is specified to be less than that of a dielectric D2.
摘要翻译： 公开了可以显着降低相移的平衡 - 不平衡变换器。 平衡 - 不平衡变换器具有与地表平行布置的三条线，即第一线b，第二线a和第三线c。 第二线a和第三线c被布置在与地面GC相同的高度处，第一线b，第二线a和第三线c中的每一个的纵向长度被指定为等于四分之一 ¼）在工作频带中的中心频率处的波长，并且第二线a和地面GC之间的电容Ca被规定为等于第二线a和第一线b之间的电容Cab。 此外，将高度方向上的第二线a和第三线c中的每一个的中心与距离第二线a和第三线c中的每一个更靠近的地面GC之间的距离h 3指定为 比在高度方向上的第一线b的中心和高度方向上的第二线a和第三线c中的每一个的中心之间的距离h 2或电介质D 3的介电常数规定为 小于电介质D 2。
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公开(公告)号：US5785653A
公开(公告)日：1998-07-28
申请号：US506202
申请日：1995-07-24
IPC分类号： A61B5/04 , A61B5/0476 , A61B5/00
CPC分类号： A61B5/7267 , A61B5/04005 , A61B5/0476 , A61B5/7203 , A61B5/726 , Y10S706/924
摘要： A live body internal condition predicting and expressing system is capable of predicting the internal condition of a live body on the basis of an electromagnetic field distribution at significantly reduced period. The system comprises an electromagnetic field distribution measuring portion, a training data generating portion generating a plurality of training data on the basis of an electromagnetic field distribution derived from a head model data designating a head model and a predetermined dipole parameter and an internal condition category data describing a relationship between the active region of a brain and the internal condition of the live body, an inference portion deriving a numeric value representative of the active region of the brain from the electromagnetic field distribution in the training data with employing a neural network having predetermined coupling coefficients representative of coupling condition between each unit forming each layer and transforming portion transforming the numeric value representative of the active region in the brain output from said inferencing means into an expression indicative of the internal condition of the live body.
摘要翻译： 活体内部状况预测和表达系统能够以显着缩短的周期在电磁场分布的基础上预测活体的内部状况。 该系统包括电磁场分布测量部分，训练数据产生部分，基于从指定头部模型和预定偶极子参数的头部模型数据和内部条件类别数据导出的电磁场分布产生多个训练数据 描述大脑的活动区域和活体的内部状态之间的关系，推理部分利用具有预定的神经网络的训练数据中的电磁场分布来导出代表脑的活动区域的数值 耦合系数表示形成每个层的每个单元与转换部分之间的耦合条件的耦合条件，将代表从所述推理装置的脑输出中的有效区域的数值转换为表示活体内部状况的表达式。
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公开(公告)号：US4930798A
公开(公告)日：1990-06-05
申请号：US259912
申请日：1988-10-19
CPC分类号： B62K21/125 , B62L3/02 , Y10T74/20287 , Y10T74/20438 , Y10T74/2078 , Y10T74/20822
摘要： A bicycle handle assembly comprises a pair of side clamps provided on a handle post, and a pair of half handle bars respectively supported by the side clamps. Each half handle bar includes a straight mounting portion extending longitudinally of the bicycle, a rest portion extending laterally outward from the mounting portion, a main grip portion provided on the rest portion at a position spaced laterally from the mounting portion, and an auxiliary grip portion disposed ahead of the rest portion and the main grip portion. The mounting portion is held by a corresponding side clamp but adjustable in position relative thereto longitudinally of the bicycle.
摘要翻译： 自行车把手组件包括设置在手柄柱上的一对侧夹具和分别由侧夹子支撑的一对半把手杆。 每个半把手杆包括一个从自行车纵向延伸的直的安装部分，一个从安装部分横向向外延伸的支撑部分，一个主把手部分设置在与该安装部分横向间隔开的位置处的该静止部分上，以及一个辅助把手部分 设置在其余部分和主把手部分之前。 安装部分由相应的侧夹具保持，但相对于自行车的纵向方向可调节。
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