摘要:
The present invention provides a process for making lapatinib and its pharmaceutically acceptable salt by use of new intermediates. A new process for obtaining a pharmaceutical form of lapatinib ditosylate monohydrate is also provided.
摘要:
The present invention provides a process for making lapatinib and its pharmaceutically acceptable salt by use of new intermediates. A new process for obtaining a pharmaceutical form of lapatinib ditosylate monohydrate is also provided.
摘要:
The present application provides intermediates for preparing prostaglandin analogues and processes for preparing prostaglandin analogues and intermediates thereof. The intermediates include: A compound of formula (6): R1 represents H, C1-C5-alkyl, or benzyl, in particular isopropyl.
摘要:
The present application provides intermediates for preparing prostaglandin analogues and processes for preparing prostaglandin analogues and intermediates thereof. The intermediates include: A compound of formula (6): R1 represents H, C1-C5-alkyl, or benzyl, in particular isopropyl.
摘要:
A power supply switch circuit with current leakage protection is used in an electronic device, and is able to prevent the erroneous actions caused by a leakage current in high-temperature environments. The power supply switch circuit comprises a transistor having an emitter, a base and a collector, a field effect transistor having a drain, a source and a gate, and at least two series-connected diodes. The emitter is connected to a voltage source. The collector is connected to a load via a forward biased diode. The drain receives a trigger signal. The source is connected a reference terminal via at least two series-connected diodes. The gate is connected to the collector via a second resistor. One terminal of a third resistor is connected to the gate, and the other terminal is connected to the reference terminal.
摘要:
The key intermediate in any synthesis of Irinotecan is 7-ethyl-10-hydroxy-20(S)-camptothecin. A process for the efficient synthesis of this intermediate is demonstrated proceeding through readily available 20(S)-camptothecin. Various other tecan compounds may be made by use of corresponding 7-alkyl-10-hydroxy-20(S)-camptothecin intermediates.