公开(公告)号：US4672318A

公开(公告)日：1987-06-09

申请号：US696909

申请日：1985-01-31

申请人： Kensuke Sekihara ,  Etsuji Yamamoto ,  Shigeru Matsui ,  Hideki Kohno

发明人： Kensuke Sekihara ,  Etsuji Yamamoto ,  Shigeru Matsui ,  Hideki Kohno

IPC分类号： G01R33/20 ,  A61B5/055 ,  A61B10/00 ,  G01R33/24 ,  G01R33/38 ,  G01R33/387

CPC分类号： G01R33/24

摘要： A method of measuring a static magnetic field distribution in a nuclear magnetic resonance (NMR) inspection system which comprises magnetic field generator for producing a static magnetic field, inclination or gradient magnetic fields and a high-frequency magnetic field, a signal detector for sensing nuclear magnetic resonance signals from an inspection sample, a computer for processing output signals from the signal detector and an output device for providing a computational result of the computer, wherein a time interval t.sub.1 from the center of a 90.degree.-pulse high-frequency magnetic field to the center of a 180.degree.-pulse high-frequency magnetic field is made different by a time difference t.sub.0 from a time interval t.sub.2 from the center of the 180.degree.-pulse high-frequency magnetic field to a peak of a spin echo, so that static magnetic field distribution is calculated based on the computer output which corresponds to the difference of the two time intervals.

摘要翻译： 一种在核磁共振（NMR）检查系统中测量静磁场分布的方法，其包括用于产生静磁场，倾斜或梯度磁场和高频磁场的磁场发生器，用于感测核的信号检测器 来自检查样本的磁共振信号，用于处理来自信号检测器的输出信号的计算机和用于提供计算机的计算结果的输出装置，其中从90°脉冲高频磁场的中心起的时间间隔t1 从180°脉冲高频磁场的中心到从180°脉冲高频磁场的中心到自旋回波的峰值的时间间隔t2由时间差t0变化到180°脉冲高频磁场的中心，因此 基于对应于两个时间间隔的差的计算机输出来计算静态磁场分布。

公开(公告)号：US4716369A

公开(公告)日：1987-12-29

申请号：US746663

申请日：1985-06-20

申请人： Kensuke Sekihara ,  Shigeru Matsui ,  Hideki Kohno ,  Etsuji Yamamoto ,  Hidemi Shiono

发明人： Kensuke Sekihara ,  Shigeru Matsui ,  Hideki Kohno ,  Etsuji Yamamoto ,  Hidemi Shiono

IPC分类号： G01R33/485 ,  G01R33/561 ,  G01R33/20

CPC分类号： G01R33/485 ,  G01R33/5615 ,  G01R33/5616

摘要： The present invention is an imaging method using three-dimensional NMR to which an echo-planar method is applied. After excitation of nuclear spins, the gradient magnetic field Gx for phase-encoding is applied and there is repeated a sequence of measuring and obtaining an echo train of spin-echoes with a constant gradient magnetic field Gx and a periodically-inverted gradient magnetic field Gy, as varying the amount of encoding, so as to obtain the three-dimensional imaging by the Fourier-conversion. Moreover, after the selective excitation of spins within an X-Y surface, a 180.degree. radio frequency pulse is applied. As varying the time difference .tau..sub..epsilon. between the interval from the excitation until the application of the 180.degree. radio frequency pulse and the interval from the application thereof until a peak of a first echo of an echo train, three-dimensional imaging is carried out with a chemical shift axis as one axis by repeating the sequence and accomplishing Fourier-conversion with .tau..sub..epsilon. as a numerical variable.

摘要翻译： 本发明是使用采用回波平面法的三维NMR的成像方法。 在激励核自旋之后，施加用于相位编码的梯度磁场Gx，并且重复测量并获得具有恒定梯度磁场Gx和周期性反转梯度磁场Gy的自旋回波回波序列的序列 ，因为改变编码量，从而通过傅里叶变换获得三维成像。 此外，在X-Y表面中的自旋选择性激发之后，施加180°射频脉冲。 随着从激励到施加180°射频脉冲的间隔与从应用到应用的间隔直到回波列的第一回波的峰值之间的时间差τεε改变，三维成像是 化学位移轴作为一个轴，通过重复该序列，并以tauε作为数值变量进行傅里叶变换。

公开(公告)号：US4472683A

公开(公告)日：1984-09-18

申请号：US420303

申请日：1982-09-20

申请人： Kensuke Sekihara ,  Etsuji Yamamoto ,  Hideki Kohno ,  Shinji Yamamoto

发明人： Kensuke Sekihara ,  Etsuji Yamamoto ,  Hideki Kohno ,  Shinji Yamamoto

IPC分类号： A61B10/00 ,  A61B5/055 ,  G01R33/48 ,  G01R33/54 ,  G01R33/08

CPC分类号： G01R33/4833

摘要： An imaging apparatus using nuclear magnetic resonance is disclosed in which both an image corresponding to the projection of a nuclear spin distribution in a to-be-inspected object on a two-dimensional plane and a display mark indicating a desired measuring position are displayed on a display face of a display device such as a CRT display, the display mark is freely moved on the display face to be set at a desired position on the display face, and magnetic field generating means for generating a static magnetic field, linear gradient field, or radio frequency magnetic field is controlled on the basis of the desired position of the display mark to obtain an image of that cross section of the object which is located at a position indicated by the display mark.

摘要翻译： 公开了一种使用核磁共振的成像装置，其中在二维平面上的被检查物体中的核自旋分布的投影和指示期望的测量位置的显示标记的图像都显示在 CRT显示器等显示装置的显示面，在显示面上自由移动显示标记，将其设定在显示面上的期望位置，产生静磁场，线性梯度场， 或者基于显示标记的期望位置来控制射频磁场，以获得位于由显示标记指示的位置处的对象的该横截面的图像。

公开(公告)号：US4558425A

公开(公告)日：1985-12-10

申请号：US413821

申请日：1982-09-01

申请人： Etsuji Yamamoto ,  Kensuke Sekihara ,  Hideki Kohno ,  Shinji Yamamoto

发明人： Etsuji Yamamoto ,  Kensuke Sekihara ,  Hideki Kohno ,  Shinji Yamamoto

IPC分类号： A61B10/00 ,  A61B5/055 ,  A61B5/107 ,  G01R33/28 ,  G01R33/38 ,  G01R33/48 ,  G01R33/58 ,  G01N15/00

CPC分类号： G01R33/381 ,  A61B5/1077 ,  G01R33/28 ,  G01R33/58

摘要： In an imaging apparatus using nuclear magnetic resonance which includes apparatus for generating a static magnetic field, a linear gradient magnetic field and a radio frequency magnetic field, respectively, signal detection device for detecting the nuclear magnetic resonant signal from an object to be inspected, a computer for calculating from the detection signal an image and output device for displaying the result of calculation by the computer, the improvement wherein the size of the object to be inspected is detected by use of ultrasonic wave or light beams and a signal indicative of the detected size of the object is applied to the linear gradient magnetic field generation apparatus so as to control the intensity of the linear gradient magnetic field.

摘要翻译： 在使用核磁共振的成像装置中，分别包括用于产生静磁场的装置，线性梯度磁场和射频磁场，用于检测来自被检体的核磁共振信号的信号检测装置， 用于从检测信号计算用于显示计算机的计算结果的图像和输出装置的计算机，其中通过使用超声波或光束来检测要检查的对象的大小，以及指示检测到的信号的信号 物体的大小被施加到线性梯度磁场产生装置，以便控制线性梯度磁场的强度。

公开(公告)号：US4437136A

公开(公告)日：1984-03-13

申请号：US389075

申请日：1982-06-16

申请人： Etsuji Yamamoto ,  Kensuke Sekihara ,  Hideki Kohno

发明人： Etsuji Yamamoto ,  Kensuke Sekihara ,  Hideki Kohno

IPC分类号： A61B10/00 ,  A61B5/055 ,  G01R33/389 ,  G05F7/00 ,  H01F5/00 ,  H01F7/18 ,  H01H47/00

CPC分类号： G05F7/00

摘要： An electromagnet having a current detecting device for detecting the current flowing through an electromagnet exciting coil, the output of which is utilized to control the power supplied to the coil to stabilize the current flowing through the coil; the electromagnet further including a separate power supply to supply current to the current detecting device which supplies current to the current detecting device when the electromagnet is not on working.

摘要翻译： 一种具有电流检测装置的电磁体，用于检测流过电磁激励线圈的电流，该电磁检测装置的输出用于控制提供给线圈的功率以稳定流经线圈的电流; 电磁体还包括单独的电源，以向电流检测装置提供电流，当电磁体不工作时，电流检测装置向电流检测装置提供电流。

公开(公告)号：US4739265A

公开(公告)日：1988-04-19

申请号：US846151

申请日：1986-03-31

申请人： Etsuji Yamamoto ,  Kensuke Sekihara ,  Hidemi Shiono ,  Hideki Kohno

发明人： Etsuji Yamamoto ,  Kensuke Sekihara ,  Hidemi Shiono ,  Hideki Kohno

IPC分类号： G01R33/485 ,  G01R33/565 ,  G01R33/20

CPC分类号： G01R33/565 ,  G01R33/485 ,  G01R33/56527

摘要： A method for providing spin density distribution images of an object, discriminated with respect to plural chemical shifts. This method is performed by repeating a measurement sequence in a spin warp imaging method, of the spin data plural times, with a time difference .DELTA..tau. between a time interval .tau..sub.1 from spin excitation to a 180.degree. RF pulse and a time interval .tau..sub.2 from the 180.degree. RF pulse to a peak of a spin echo, altering .DELTA..tau. in the ways corresponding the number of chemical shifts to be discriminated from one another, subjecting the respective spin data to two-dimensional Fourier transform to provide plural sets of spin data for respective coordinates in a spatial domain, and solving simultaneous equations of the sets of spin data to provide spin densities corresponding to the respective chemical shifts.

摘要翻译： 一种用于提供对象的自旋密度分布图像的方法，其被鉴别为多个化学位移。 该方法通过在旋转数据成像方法中重复自旋数据多次的测量序列，其中从自旋激发到180°RF脉冲的时间间隔τ1与时间间隔τ2之间的时间差DELTAτ 从180°RF脉冲到自旋回波的峰值，以相应于要彼此区分的化学位移数的方式改变DELTA tau，对各自旋转数据进行二维傅里叶变换以提供多组旋转 用于空间域中的各个坐标的数据，以及求解自旋数据组的联立方程以提供对应于各个化学位移的自旋密度。

公开(公告)号：US4777443A

公开(公告)日：1988-10-11

申请号：US119489

申请日：1987-11-12

申请人： Masao Yabusaki ,  Etsuji Yamamoto ,  Takashi Onodera ,  Yukiko Ogura ,  Hideaki Nakane ,  Shigeru Matsui ,  Hideki Kohno

发明人： Masao Yabusaki ,  Etsuji Yamamoto ,  Takashi Onodera ,  Yukiko Ogura ,  Hideaki Nakane ,  Shigeru Matsui ,  Hideki Kohno

IPC分类号： G01R33/035 ,  G01R33/36 ,  G01R33/20

CPC分类号： G01R33/326 ,  G01R33/0358

摘要： Disclosed in a nuclear magnetic resonance (NMR) based inspection apparatus using an SQUID flux meter for detecting a small NMR signal, in which a receiving coil for receiving the NMR signal from an object is connected to a mixer, which mixes a reference high-frequency signal with the NMR signal so that the NMR signal is reduced to a low-frequency signal having a differential component of frequencies of both signals, and the low-frequency signal is applied to the input coil of the SQUID flux meter so that it is converted into a voltage signal. The mixer circuit includes Schottky diodes operative at a liquid helium temperature or Josephson junctions, and the portions of apparatus from the reception coil up to the SQUID flux meter are operated in a superconductive state at a liquid helium temperature.

摘要翻译： 在使用SQUID通量计检测小型NMR信号的基于核磁共振（NMR）的检查装置中公开了一种用于从物体接收NMR信号的接收线圈连接到混频器，该混频器将参考高频 用NMR信号进行信号，使得NMR信号被减少到具有两个信号的频率的差分分量的低频信号，并且低频信号被施加到SQUID通量计的输入线圈，使得其被转换 变成电压信号。 混频器电路包括以液氦温度或约瑟夫逊结操作的肖特基二极管，并且从接收线圈到SQUID通量计的装置部分在液氦温度下处于超导状态。

公开(公告)号：US4683433A

公开(公告)日：1987-07-28

申请号：US636995

申请日：1984-08-02

申请人： Etsuji Yamamoto ,  Hideki Kohno ,  Masao Kuroda ,  Shigeru Matsui ,  Hidemi Shiono

发明人： Etsuji Yamamoto ,  Hideki Kohno ,  Masao Kuroda ,  Shigeru Matsui ,  Hidemi Shiono

IPC分类号： G01R33/20 ,  A61B5/055 ,  A61B10/00 ,  G01R33/48 ,  G01R33/54 ,  G01R33/56

CPC分类号： G01R33/482 ,  G01R33/56

摘要： An NMR imaging apparatus and method for detecting a nuclear spin resonance signal from an object, which is placed in a magnetic field, to produce images of the object. At an instant when the spins come into phase after the signal detection by a first spin excitation, RF magnetic field pulses are applied for rotating the direction of the spin to that opposite to the initial state. After that, the spin excitation and the signal direction of second time are conducted to measure the data which are different in the effect of the relaxation time from the first measurements. By repeating these sequences, it is possible to produce a plurality of images such as an intensity image or a relaxation time enhanced image.

摘要翻译： 一种用于检测放置在磁场中的物体的核自旋共振信号的NMR成像设备和方法，以产生物体的图像。 在通过第一自旋激发在信号检测之后自旋进入相位的瞬间，施加RF磁场脉冲以将旋转方向旋转到与初始状态相反的方向。 之后，进行自旋激励和第二次的信号方向，以测量与第一次测量相比，松弛时间的影响不同的数据。 通过重复这些序列，可以产生多个图像，例如强度图像或弛豫时间增强图像。

公开(公告)号：US4625170A

公开(公告)日：1986-11-25

申请号：US635154

申请日：1984-07-27

申请人： Etsuji Yamamoto ,  Shigeru Matsui ,  Masuo Kuroda ,  Hideki Kohno

发明人： Etsuji Yamamoto ,  Shigeru Matsui ,  Masuo Kuroda ,  Hideki Kohno

IPC分类号： G01R33/20 ,  A61B5/055 ,  A61B10/00 ,  G01R33/48 ,  G01R33/565

CPC分类号： G01R33/56518

摘要： An NMR imaging method and apparatus of the type in which a 180-degree RF pulse is applied to generate a spin echo after the selective excitation of a spin by a 90-degree RF pulse. A dummy gradient field, which has the same direction and intensity as those of a gradient field to be applied when the spin echo is observed, is applied between said 90-degree RF pulse and said 180-degree RF pulse so that the instant of starting the application of the gradient field for signal observation is advanced to the extent corresponding to said dummy gradient field.

摘要翻译： 一种NMR成像方法和装置，其中施加180度RF脉冲以在旋转选择性激发90度RF脉冲之后产生自旋回波。 在所述90度RF脉冲和所述180度RF脉冲之间，施加与观察到自旋回波时要施加的梯度场相同的方向和强度的虚拟梯度场，使得起始时刻 将用于信号观察的梯度场的应用提前到对应于所述虚拟梯度场的程度。

公开(公告)号：US4791369A

公开(公告)日：1988-12-13

申请号：US72035

申请日：1987-07-10

申请人： Etsuji Yamamoto ,  Hideki Kohno

发明人： Etsuji Yamamoto ,  Hideki Kohno

IPC分类号： A61B5/055 ,  A61B10/00 ,  G01R33/24 ,  G01R33/48 ,  G01R33/565 ,  G01R33/20

CPC分类号： G01R33/24 ,  G01R33/56563 ,  G01R33/56518

摘要： A method of finding error distribution in the static magnetic field and distribution of deviations from straight lines in the gradient magnetic fields of an NMR imaging apparatus which employs the applied spin-warp method. A phantom whose shape has been known is measured in the read-out gradient magnetic fields having different polarities to obtain two spin density distribution images. The two images are then compared with the shape of said phantom to measure the distortion distributions of the images. Error in the static magnetic field and deviations of the gradient magnetic fields from the straight lines are analyzed from the distortion distributions. From the thus obtained error distribution, furthermore, distortion induced in imaging the object is estimated, and the distortion contained in the image that is reconstructed from the spin density of the object by the spin-warp method is corrected using the thus estimated value.

摘要翻译： 在使用所采用的旋转翘曲方法的NMR成像装置的梯度磁场中找到静态磁场中的误差分布和偏离直线偏差的方法。 在具有不同极性的读出梯度磁场中测量其形状已知的体模，以获得两个自旋密度分布图像。 然后将两个图像与所述体模的形状进行比较，以测量图像的失真分布。 从失真分布中分析静态磁场的误差和梯度磁场与直线的偏差。 此外，根据这样得到的误差分布，估计在物体成像时引起的失真，并且使用这样估计的值来校正通过旋转扭曲方法从物体的自旋密度重构的图像中包含的失真。