公开(公告)号：US20100121308A1

公开(公告)日：2010-05-13

申请号：US12572137

申请日：2009-10-01

申请人： Ketan P. Muni ,  Hung V. HA ,  Joshua Makower ,  John H. Morriss ,  John Y. Chang ,  William M. Facteau ,  Amrish Jayprakash Walke

发明人： Ketan P. Muni ,  Hung V. HA ,  Joshua Makower ,  John H. Morriss ,  John Y. Chang ,  William M. Facteau ,  Amrish Jayprakash Walke

IPC分类号： A61M31/00

CPC分类号： A61M31/002 ,  A61B5/064 ,  A61B5/411 ,  A61B5/416 ,  A61B17/24 ,  A61B17/320725 ,  A61B17/320758 ,  A61B17/320783 ,  A61B17/3478 ,  A61B34/20 ,  A61B90/361 ,  A61B2017/22061 ,  A61B2034/105 ,  A61B2034/107 ,  A61B2034/2048 ,  A61B2034/2051 ,  A61B2090/365 ,  A61F2/18 ,  A61F2/82 ,  A61F2/92 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2250/0039 ,  A61M25/007 ,  A61M25/10 ,  A61M31/00 ,  A61M2025/004 ,  A61M2025/1052

摘要： Devices and methods for delivering drugs and other therapeutic or diagnostic substances to desired locations within the bodies of human or non-human animal subjects. An implantable delivery device comprising a reservoir is initially attached to a deliver catheter or delivery tool and is introduced into the body and positioned at a desired site. A therapeutic or diagnostic substance is then introduced into the reservoir and the delivery catheter or deliver tool is then removed, leaving the implantable delivery device implanted within the body. The substance is then delivered from the reservoir at a rate that causes the desire diagnostic or therapeutic effect. Also provided are substance eluting stents that elute substance from a selected surface of the stent (e.g., the outer surface) but not from another surface of the stent (e.g., the inner surface).

摘要翻译： 将药物和其他治疗或诊断物质递送到人类或非人类动物受试者体内所需位置的装置和方法。 包括储存器的可植入递送装置最初附接到递送导管或递送工具，并且被引入到身体中并且定位在期望的位置。 然后将治疗或诊断物质引入储存器中，然后移出输送导管或递送工具，使植入式输送装置植入体内。 然后将物质以引起期望诊断或治疗效果的速率从储存器输送。 还提供了从支架的选定表面（例如外表面）洗脱物质而不从支架的另一表面（例如，内表面）洗脱物质的物质洗脱支架。

公开(公告)号：US20080319424A1

公开(公告)日：2008-12-25

申请号：US12143698

申请日：2008-06-20

申请人： Ketan P. Muni ,  Hung V. Ha ,  Joshua Makower ,  John H. Morriss ,  John Y. Chang ,  William M. Facteau ,  Amrish Jayprakash Walke

发明人： Ketan P. Muni ,  Hung V. Ha ,  Joshua Makower ,  John H. Morriss ,  John Y. Chang ,  William M. Facteau ,  Amrish Jayprakash Walke

IPC分类号： A61K9/22 ,  A61M31/00 ,  A61M29/02

CPC分类号： A61M31/002 ,  A61B5/064 ,  A61B5/411 ,  A61B5/416 ,  A61B17/24 ,  A61B17/320725 ,  A61B17/320758 ,  A61B17/320783 ,  A61B17/3478 ,  A61B34/20 ,  A61B90/361 ,  A61B2017/22061 ,  A61B2034/105 ,  A61B2034/107 ,  A61B2034/2048 ,  A61B2034/2051 ,  A61B2090/365 ,  A61F2/18 ,  A61F2/82 ,  A61F2/92 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2250/0039 ,  A61M25/007 ,  A61M25/10 ,  A61M31/00 ,  A61M2025/004 ,  A61M2025/1052

摘要： Devices and methods for delivering drugs and other therapeutic or diagnostic substances to desired locations within the bodies of human or non-human animal subjects. An implantable delivery device comprising a reservoir is initially attached to a deliver catheter or delivery tool and is introduced into the body and positioned at a desired site. A therapeutic or diagnostic substance is then introduced into the reservoir and the delivery catheter or deliver tool is then removed, leaving the implantable delivery device implanted within the body. The substance is then delivered from the reservoir at a rate that causes the desire diagnostic or therapeutic effect. Also provided are substance eluting stents that elute substance from a selected surface of the stent (e.g., the outer surface) but not from another surface of the stent (e.g., the inner surface).

摘要翻译： 将药物和其他治疗或诊断物质递送到人类或非人类动物受试者体内所需位置的装置和方法。 包括储存器的可植入递送装置最初附接到递送导管或递送工具，并且被引入到身体中并且定位在期望的位置。 然后将治疗或诊断物质引入储存器中，然后移出输送导管或递送工具，使植入式输送装置植入体内。 然后将物质以引起期望诊断或治疗效果的速率从储存器输送。 还提供了从支架的选定表面（例如外表面）洗脱物质而不从支架的另一表面（例如，内表面）洗脱物质的物质洗脱支架。

公开(公告)号：US08858586B2

公开(公告)日：2014-10-14

申请号：US11655794

申请日：2007-01-18

申请人： John Y. Chang ,  Joshua Makower ,  Julia D. Vrany ,  John H. Morriss ,  Ketan P. Muni ,  Isaac J. Kim ,  Hung V. Ha ,  William M. Facteau ,  Amrish Jayprakash Walke

发明人： John Y. Chang ,  Joshua Makower ,  Julia D. Vrany ,  John H. Morriss ,  Ketan P. Muni ,  Isaac J. Kim ,  Hung V. Ha ,  William M. Facteau ,  Amrish Jayprakash Walke

IPC分类号： A61M29/00

CPC分类号： A61M29/00 ,  A61B1/233 ,  A61B17/12104 ,  A61B17/12136 ,  A61B17/1657 ,  A61B17/1688 ,  A61B17/24 ,  A61B17/320016 ,  A61B17/320725 ,  A61B34/20 ,  A61B2017/00292 ,  A61B2017/246 ,  A61B2034/2051 ,  A61B2090/3764 ,  A61B2503/40 ,  A61M25/0041 ,  A61M25/0054 ,  A61M25/0662 ,  A61M25/09 ,  A61M25/1002 ,  A61M29/02 ,  A61M2025/0008 ,  A61M2025/1079 ,  A61M2029/025 ,  A61M2210/0618 ,  A61M2210/1028

摘要： Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodeling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat; implanting a device, cells or tissues; removing matter from the ear, nose or throat; delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices (e.g., guide catheters, tubes, guidewires, elongate probes, other elongate members) may be used to facilitate insertion of working devices (e.g. catheters e.g. balloon catheters, guidewires, tissue cutting or remodeling devices, devices for implanting elements like stents, electrosurgical devices, energy emitting devices, devices for delivering diagnostic or therapeutic agents, substance delivery implants, scopes etc.) into the paranasal sinuses or other structures in the ear, nose or throat. Specific devices (e.g., tubular guides, guidewires, balloon catheters, tubular sheaths) are provided as are methods for manufacturing and using such devices to treat disorders of the ear, nose or throat.

摘要翻译： 使用具有柔性或刚性器械的微创方法诊断和/或治疗鼻窦炎和其他耳朵，鼻子和喉咙疾病。 各种方法和装置用于重建或改变耳朵，鼻子或喉咙中的窦口或导管或其他解剖结构的形状，尺寸或构型; 植入装置，细胞或组织; 从耳朵，鼻子或喉咙去除物质; 提供诊断或治疗物质或执行其他诊断或治疗程序。 可以使用引入装置（例如，引导导管，管，导线，细长探针，其它细长构件）来促进工作装置（例如，导管例如球囊导管，导线，组织切割或重塑装置，用于植入元件如支架的装置， 电外科装置，能量发射装置，用于递送诊断或治疗剂，物质输送植入物，范围等的装置）到耳鼻窦或耳朵，鼻子或喉咙中的其他结构中。 提供特定装置（例如，管状引导件，导丝，气囊导管，管状护套），制造和使用这种装置来治疗耳朵，鼻子或喉咙的障碍的方法。

公开(公告)号：US08114062B2

公开(公告)日：2012-02-14

申请号：US12572137

申请日：2009-10-01

申请人： Ketan P. Muni ,  Hung V. Ha ,  Joshua Makower ,  John H. Morriss ,  John Y. Chang ,  William M. Facteau ,  Amrish Jayprakash Walke

发明人： Ketan P. Muni ,  Hung V. Ha ,  Joshua Makower ,  John H. Morriss ,  John Y. Chang ,  William M. Facteau ,  Amrish Jayprakash Walke

IPC分类号： A61M31/00 ,  A61M29/00

CPC分类号： A61M31/002 ,  A61B5/064 ,  A61B5/411 ,  A61B5/416 ,  A61B17/24 ,  A61B17/320725 ,  A61B17/320758 ,  A61B17/320783 ,  A61B17/3478 ,  A61B34/20 ,  A61B90/361 ,  A61B2017/22061 ,  A61B2034/105 ,  A61B2034/107 ,  A61B2034/2048 ,  A61B2034/2051 ,  A61B2090/365 ,  A61F2/18 ,  A61F2/82 ,  A61F2/92 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2250/0039 ,  A61M25/007 ,  A61M25/10 ,  A61M31/00 ,  A61M2025/004 ,  A61M2025/1052

摘要： Devices and methods for delivering drugs and other therapeutic or diagnostic substances to desired locations within the bodies of human or non-human animal subjects. An implantable delivery device comprising a reservoir is initially attached to a deliver catheter or delivery tool and is introduced into the body and positioned at a desired site. A therapeutic or diagnostic substance is then introduced into the reservoir and the delivery catheter or deliver tool is then removed, leaving the implantable delivery device implanted within the body. The substance is then delivered from the reservoir at a rate that causes the desire diagnostic or therapeutic effect. Also provided are substance eluting stents that elute substance from a selected surface of the stent (e.g., the outer surface) but not from another surface of the stent (e.g., the inner surface).

摘要翻译： 将药物和其他治疗或诊断物质递送到人类或非人类动物受试者体内所需位置的装置和方法。 包括储存器的可植入递送装置最初附接到递送导管或递送工具，并且被引入到身体中并且定位在期望的位置。 然后将治疗或诊断物质引入储存器中，然后移出输送导管或递送工具，使植入式输送装置植入体内。 然后将物质以引起期望诊断或治疗效果的速率从储存器输送。 还提供了从支架的选定表面（例如外表面）洗脱物质而不从支架的另一表面（例如，内表面）洗脱物质的物质洗脱支架。

公开(公告)号：US07410480B2

公开(公告)日：2008-08-12

申请号：US11234395

申请日：2005-09-23

申请人： Ketan P. Muni ,  Hung V. Ha ,  Joshua Makower ,  John H. Morriss ,  John Y. Chang ,  William M. Facteau ,  Amrish Jayprakash Walke

发明人： Ketan P. Muni ,  Hung V. Ha ,  Joshua Makower ,  John H. Morriss ,  John Y. Chang ,  William M. Facteau ,  Amrish Jayprakash Walke

IPC分类号： A61M31/00

CPC分类号： A61M31/002 ,  A61B5/064 ,  A61B5/411 ,  A61B5/416 ,  A61B17/24 ,  A61B17/320725 ,  A61B17/320758 ,  A61B17/320783 ,  A61B17/3478 ,  A61B34/20 ,  A61B90/361 ,  A61B2017/22061 ,  A61B2034/105 ,  A61B2034/107 ,  A61B2034/2048 ,  A61B2034/2051 ,  A61B2090/365 ,  A61F2/18 ,  A61F2/82 ,  A61F2/92 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2250/0039 ,  A61M25/007 ,  A61M25/10 ,  A61M31/00 ,  A61M2025/004 ,  A61M2025/1052

摘要： Devices and methods for delivering drugs and other therapeutic or diagnostic substances to desired locations within the bodies of human or non-human animal subjects. An implantable delivery device comprising a reservoir is initianlly attached to a deliver catheter or delivery tool and is introduced into the body and positioned at a desired site. A therapeutic or diagnostic substance is then introduced into the reservoir and the delivery catheter or deliver tool is then removed, leaving the implantable delivery device implanted within the body. The substance is then delivered from the reservoir at a rate that causes the desire diagnostic or therapeutic effect. Also provided are substance eluting stents that elute substance from a selected surface of the stent (e.g., the outer surface) but not from another surface of the stent (e.g., the inner surface).

摘要翻译： 将药物和其他治疗或诊断物质递送到人类或非人类动物受试者体内所需位置的装置和方法。 包括储存器的可植入递送装置初始地附接到递送导管或递送工具，并且被引入体内并且定位在期望的位置。 然后将治疗或诊断物质引入储存器中，然后移出输送导管或递送工具，使植入式输送装置植入体内。 然后将物质以引起期望诊断或治疗效果的速率从储存器输送。 还提供了从支架的选定表面（例如外表面）洗脱物质而不从支架的另一表面（例如，内表面）洗脱物质的物质洗脱支架。

公开(公告)号：US07803150B2

公开(公告)日：2010-09-28

申请号：US11150847

申请日：2005-06-10

申请人： John Y. Chang ,  Joshua Makower ,  Julia D. Vrany ,  John H. Morriss ,  Ketan P. Muni ,  Isaac J. Kim ,  Hung Ha ,  William M. Facteau ,  Amrish Jayprakash Walke

发明人： John Y. Chang ,  Joshua Makower ,  Julia D. Vrany ,  John H. Morriss ,  Ketan P. Muni ,  Isaac J. Kim ,  Hung Ha ,  William M. Facteau ,  Amrish Jayprakash Walke

IPC分类号： A61M31/00

CPC分类号： A61M29/00 ,  A61B1/233 ,  A61B17/12104 ,  A61B17/12136 ,  A61B17/1657 ,  A61B17/1688 ,  A61B17/24 ,  A61B17/320016 ,  A61B17/320725 ,  A61B34/20 ,  A61B2017/00292 ,  A61B2017/246 ,  A61B2034/2051 ,  A61B2090/3764 ,  A61B2503/40 ,  A61M25/0041 ,  A61M25/0054 ,  A61M25/0662 ,  A61M25/09 ,  A61M25/1002 ,  A61M29/02 ,  A61M2025/0008 ,  A61M2025/1079 ,  A61M2029/025 ,  A61M2210/0618 ,  A61M2210/1028

摘要： Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodeling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat; implanting a device, cells or tissues; removing matter from the ear, nose or throat; delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices (e.g., guide catheters, tubes, guidewires, elongate probes, other elongate members) may be used to facilitate insertion of working devices (e.g. catheters e.g. balloon catheters, guidewires, tissue cutting or remodeling devices, devices for implanting elements like stents, electrosurgical devices, energy emitting devices, devices for delivering diagnostic or therapeutic agents, substance delivery implants, scopes etc.) into the paranasal sinuses or other structures in the ear, nose or throat. Specific devices (e.g., tubular guides, guidewires, balloon catheters, tubular sheaths) are provided as are methods for manufacturing and using such devices to treat disorders of the ear, nose or throat.

摘要翻译： 使用具有柔性或刚性器械的微创方法诊断和/或治疗鼻窦炎和其他耳朵，鼻子和喉咙疾病。 各种方法和装置用于重建或改变耳朵，鼻子或喉咙中的窦口或导管或其他解剖结构的形状，尺寸或构型; 植入装置，细胞或组织; 从耳朵，鼻子或喉咙去除物质; 提供诊断或治疗物质或执行其他诊断或治疗程序。 可以使用引入装置（例如，引导导管，管，导线，细长探针，其它细长构件）来促进工作装置（例如，导管例如球囊导管，导线，组织切割或重塑装置，用于植入元件如支架的装置， 电外科装置，能量发射装置，用于递送诊断或治疗剂，物质输送植入物，范围等的装置）到耳鼻窦或耳朵，鼻子或喉咙中的其他结构中。 提供特定装置（例如，管状引导件，导丝，气囊导管，管状护套），制造和使用这种装置来治疗耳朵，鼻子或喉咙的障碍的方法。

公开(公告)号：US20100174308A1

公开(公告)日：2010-07-08

申请号：US12727190

申请日：2010-03-18

申请人： John Y. Chang ,  Joshua Makower ,  Julia D. Vrany ,  John H. Morriss ,  Ketan P. Muni ,  Isaac J. Kim ,  Hung Ha ,  William M. Facteau ,  Amrish Jayprakash Walke

发明人： John Y. Chang ,  Joshua Makower ,  Julia D. Vrany ,  John H. Morriss ,  Ketan P. Muni ,  Isaac J. Kim ,  Hung Ha ,  William M. Facteau ,  Amrish Jayprakash Walke

IPC分类号： A61M29/02

CPC分类号： A61M29/00 ,  A61B1/233 ,  A61B17/12104 ,  A61B17/12136 ,  A61B17/1657 ,  A61B17/1688 ,  A61B17/24 ,  A61B17/320016 ,  A61B17/320725 ,  A61B34/20 ,  A61B2017/00292 ,  A61B2017/246 ,  A61B2034/2051 ,  A61B2090/3764 ,  A61B2503/40 ,  A61M25/0041 ,  A61M25/0054 ,  A61M25/0662 ,  A61M25/09 ,  A61M25/1002 ,  A61M29/02 ,  A61M2025/0008 ,  A61M2025/1079 ,  A61M2029/025 ,  A61M2210/0618 ,  A61M2210/1028

摘要： Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodeling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat; implanting a device, cells or tissues; removing matter from the ear, nose or throat; delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices (e.g., guide catheters, tubes, guidewires, elongate probes, other elongate members) may be used to facilitate insertion of working devices (e.g. catheters e.g. balloon catheters, guidewires, tissue cutting or remodeling devices, devices for implanting elements like stents, electrosurgical devices, energy emitting devices, devices for delivering diagnostic or therapeutic agents, substance delivery implants, scopes etc.) into the paranasal sinuses or other structures in the ear, nose or throat. Specific devices (e.g., tubular guides, guidewires, balloon catheters, tubular sheaths) are provided as are methods for manufacturing and using such devices to treat disorders of the ear, nose or throat.

公开(公告)号：US20100174138A1

公开(公告)日：2010-07-08

申请号：US12729109

申请日：2010-03-22

申请人： John Y. Chang ,  Joshua Makower ,  Julia D. Vrany ,  John H. Morriss ,  Ketan P. Muni ,  Isaac J. Kim ,  Hung Ha ,  William M. Facteau ,  Amrish Jayprakash Walke

发明人： John Y. Chang ,  Joshua Makower ,  Julia D. Vrany ,  John H. Morriss ,  Ketan P. Muni ,  Isaac J. Kim ,  Hung Ha ,  William M. Facteau ,  Amrish Jayprakash Walke

IPC分类号： A61B17/94

CPC分类号： A61M29/00 ,  A61B1/233 ,  A61B17/12104 ,  A61B17/12136 ,  A61B17/1657 ,  A61B17/1688 ,  A61B17/24 ,  A61B17/320016 ,  A61B17/320725 ,  A61B34/20 ,  A61B2017/00292 ,  A61B2017/246 ,  A61B2034/2051 ,  A61B2090/3764 ,  A61B2503/40 ,  A61M25/0041 ,  A61M25/0054 ,  A61M25/0662 ,  A61M25/09 ,  A61M25/1002 ,  A61M29/02 ,  A61M2025/0008 ,  A61M2025/1079 ,  A61M2029/025 ,  A61M2210/0618 ,  A61M2210/1028

摘要： Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodeling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat; implanting a device, cells or tissues; removing matter from the ear, nose or throat; delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices (e.g., guide catheters, tubes, guidewires, elongate probes, other elongate members) may be used to facilitate insertion of working devices (e.g. catheters e.g. balloon catheters, guidewires, tissue cutting or remodeling devices, devices for implanting elements like stents, electrosurgical devices, energy emitting devices, devices for delivering diagnostic or therapeutic agents, substance delivery implants, scopes etc.) into the paranasal sinuses or other structures in the ear, nose or throat. Specific devices (e.g., tubular guides, guidewires, balloon catheters, tubular sheaths) are provided as are methods for manufacturing and using such devices to treat disorders of the ear, nose or throat.

摘要翻译： 使用具有柔性或刚性器械的微创方法诊断和/或治疗鼻窦炎和其他耳朵，鼻子和喉咙疾病。 各种方法和装置用于重建或改变耳朵，鼻子或喉咙中的窦口或导管或其他解剖结构的形状，尺寸或构型; 植入装置，细胞或组织; 从耳朵，鼻子或喉咙去除物质; 提供诊断或治疗物质或执行其他诊断或治疗程序。 可以使用引入装置（例如，引导导管，管，导线，细长探针，其它细长构件）来促进工作装置（例如，导管例如球囊导管，导线，组织切割或重塑装置，用于植入元件如支架的装置， 电外科装置，能量发射装置，用于递送诊断或治疗剂，物质输送植入物，范围等的装置）到耳鼻窦或耳朵，鼻子或喉咙中的其他结构中。 提供特定装置（例如，管状引导件，导丝，气囊导管，管状护套），制造和使用这种装置来治疗耳朵，鼻子或喉咙的障碍的方法。

公开(公告)号：US20090093823A1

公开(公告)日：2009-04-09

申请号：US11928160

申请日：2007-10-30

申请人： John Y. Chang ,  Joshua Makower ,  Julia D. Vrany ,  John H. Morriss ,  Ketan P. Muni ,  Isaac J. Kim ,  Hung Ha ,  William M. Facteau ,  Amrish Jayprakash Walke

发明人： John Y. Chang ,  Joshua Makower ,  Julia D. Vrany ,  John H. Morriss ,  Ketan P. Muni ,  Isaac J. Kim ,  Hung Ha ,  William M. Facteau ,  Amrish Jayprakash Walke

IPC分类号： A61B17/24 ,  A61B17/00 ,  A61M29/00

CPC分类号： A61M29/00 ,  A61B1/233 ,  A61B17/12104 ,  A61B17/12136 ,  A61B17/1657 ,  A61B17/1688 ,  A61B17/24 ,  A61B17/320016 ,  A61B17/320725 ,  A61B34/20 ,  A61B2017/00292 ,  A61B2017/246 ,  A61B2034/2051 ,  A61B2090/3764 ,  A61B2503/40 ,  A61M25/0041 ,  A61M25/0054 ,  A61M25/0662 ,  A61M25/09 ,  A61M25/1002 ,  A61M29/02 ,  A61M2025/0008 ,  A61M2025/1079 ,  A61M2029/025 ,  A61M2210/0618 ,  A61M2210/1028

摘要： Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodeling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat; implanting a device, cells or tissues; removing matter from the ear, nose or throat; delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices (e.g., guide catheters, tubes, guidewires, elongate probes, other elongate members) may be used to facilitate insertion of working devices (e.g. catheters e.g. balloon catheters, guidewires, tissue cutting or remodeling devices, devices for implanting elements like stents, electrosurgical devices, energy emitting devices, devices for delivering diagnostic or therapeutic agents, substance delivery implants, scopes etc.) into the paranasal sinuses or other structures in the ear, nose or throat. Specific devices (e.g., tubular guides, guidewires, balloon catheters, tubular sheaths) are provided as are methods for manufacturing and using such devices to treat disorders of the ear, nose or throat.

摘要翻译： 使用具有柔性或刚性器械的微创方法诊断和/或治疗鼻窦炎和其他耳朵，鼻子和喉咙疾病。 各种方法和装置用于重建或改变耳朵，鼻子或喉咙中的窦口或导管或其他解剖结构的形状，尺寸或构型; 植入装置，细胞或组织; 从耳朵，鼻子或喉咙去除物质; 提供诊断或治疗物质或执行其他诊断或治疗程序。 可以使用引入装置（例如，引导导管，管，导线，细长探针，其它细长构件）来促进工作装置（例如，导管例如球囊导管，导线，组织切割或重塑装置，用于植入元件如支架的装置， 电外科装置，能量发射装置，用于递送诊断或治疗剂，物质输送植入物，范围等的装置）到耳鼻窦或耳朵，鼻子或喉咙中的其他结构中。 提供特定装置（例如，管状引导件，导丝，气囊导管，管状护套），制造和使用这种装置来治疗耳朵，鼻子或喉咙的障碍的方法。

公开(公告)号：US08715169B2

公开(公告)日：2014-05-06

申请号：US11928097

申请日：2007-10-30

申请人： John Y. Chang ,  Joshua Makower ,  Julia D. Vrany ,  John H. Morriss ,  Ketan P. Muni ,  Isaac J. Kim ,  Hung Ha ,  William M. Facteau ,  Amrish Jayprakash Walke

发明人： John Y. Chang ,  Joshua Makower ,  Julia D. Vrany ,  John H. Morriss ,  Ketan P. Muni ,  Isaac J. Kim ,  Hung Ha ,  William M. Facteau ,  Amrish Jayprakash Walke

IPC分类号： A61B1/04 ,  A61B1/00

CPC分类号： A61M29/00 ,  A61B1/233 ,  A61B17/12104 ,  A61B17/12136 ,  A61B17/1657 ,  A61B17/1688 ,  A61B17/24 ,  A61B17/320016 ,  A61B17/320725 ,  A61B34/20 ,  A61B2017/00292 ,  A61B2017/246 ,  A61B2034/2051 ,  A61B2090/3764 ,  A61B2503/40 ,  A61M25/0041 ,  A61M25/0054 ,  A61M25/0662 ,  A61M25/09 ,  A61M25/1002 ,  A61M29/02 ,  A61M2025/0008 ,  A61M2025/1079 ,  A61M2029/025 ,  A61M2210/0618 ,  A61M2210/1028

摘要： Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodeling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat; implanting a device, cells or tissues; removing matter from the ear, nose or throat; delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices (e.g., guide catheters, tubes, guidewires, elongate probes, other elongate members) may be used to facilitate insertion of working devices (e.g. catheters e.g. balloon catheters, guidewires, tissue cutting or remodeling devices, devices for implanting elements like stents, electrosurgical devices, energy emitting devices, devices for delivering diagnostic or therapeutic agents, substance delivery implants, scopes etc.) into the paranasal sinuses or other structures in the ear, nose or throat. Specific devices (e.g., tubular guides, guidewires, balloon catheters, tubular sheaths) are provided as are methods for manufacturing and using such devices to treat disorders of the ear, nose or throat.