公开(公告)号：US20200149083A1

公开(公告)日：2020-05-14

申请号：US16618048

申请日：2018-05-31

申请人： KnipBio, Inc.

发明人： Lawrence F. Feinberg ,  Daniel R. Smith ,  Bonnie D. McAvoy ,  Catherine J. Pujol-Baxley ,  Christopher J. Marx

IPC分类号： C12P23/00 ,  B01D3/00 ,  A23K50/80 ,  A61K9/00 ,  A23K20/179 ,  A61K31/122 ,  C12N15/74

摘要： Non-naturally occurring microorganisms are provided that produce C40 carotenoid compound(s), utilizing exogenously added enzyme activities. Methods of producing C40 carotenoid compounds in microbial cultures, and feed and nutritional supplement compositions that include the C40 carotenoid compounds produced in the microbial cultures, are also provided.

公开(公告)号：US20230348948A1

公开(公告)日：2023-11-02

申请号：US18071945

申请日：2022-11-30

申请人： KnipBio, Inc.

发明人： Lawrence F. Feinberg ,  Daniel R. Smith ,  Bonnie D. McAvoy ,  Catherine J. Pujol-Baxley ,  Christopher J. Marx

IPC分类号： A23K50/80 ,  A61K31/122 ,  C12P23/00 ,  A23K20/179 ,  C12N15/74 ,  A61K9/00 ,  B01D3/00

CPC分类号： C12P23/00 ,  A23K20/179 ,  A23K50/80 ,  A61K9/0056 ,  A61K31/122 ,  B01D3/001 ,  C12N15/74

摘要： Non-naturally occurring microorganisms are provided that produce C40 carotenoid compound(s), utilizing exogenously added enzyme activities. Methods of producing C40 carotenoid compounds in microbial cultures, and feed and nutritional supplement compositions that include the C40 carotenoid compounds produced in the microbial cultures, are also provided.

公开(公告)号：US11326171B2

公开(公告)日：2022-05-10

申请号：US15774731

申请日：2016-11-09

申请人： KnipBio, Inc.

发明人： Lawrence F. Feinberg ,  Christopher J. Marx ,  Max A. Wall ,  Daniel R. Smith ,  Catherine J. Pujol-Baxley ,  Bonnie D. McAvoy

IPC分类号： C12N9/96 ,  C12N15/52 ,  A23K10/12 ,  A23K50/80 ,  A23L33/175 ,  C12P13/00 ,  C12P21/00 ,  C12P11/00 ,  A23L5/44 ,  A23K20/10 ,  A23L33/15 ,  A23K20/142

摘要： Non-naturally occurring microorganisms are provided that produce taurine and/or taurine precursors, e.g., hypotaurine, sulfoacetaldehyde, or cysteate, utilizing exogenously added enzyme activities. Methods of producing taurine and/or taurine precursors in microbial cultures, and feed and nutritional supplement compositions that include taurine and/or taurine precursors produced in the microbial cultures, such as taurine- and/or taurine precursor-containing biomass, are also provided.

公开(公告)号：US20190062757A1

公开(公告)日：2019-02-28

申请号：US15774731

申请日：2016-11-09

申请人： KnipBio, Inc.

发明人： Lawrence F. Feinberg ,  Christopher J. Marx ,  Max A. Wall ,  Daniel R. Smith ,  Catherine J. Pujol-Baxley ,  Bonnie D. McAvoy

IPC分类号： C12N15/52 ,  C12P13/00 ,  A23K10/12 ,  A23K20/142 ,  A23K50/80 ,  A23L33/175

摘要： Non-naturally occurring microorganisms are provided that produce taurine and/or taurine precursors, e.g., hypotaurine, sulfoacetaldehyde, or cysteate, utilizing exogenously added enzyme activities. Methods of producing taurine and/or taurine precursors in microbial cultures, and feed and nutritional supplement compositions that include taurine and/or taurine precursors produced in the microbial cultures, such as taurine- and/or taurine precursor-containing biomass, are also provided.

公开(公告)号：US11560583B2

公开(公告)日：2023-01-24

申请号：US16618048

申请日：2018-05-31

申请人： KnipBio, Inc.

发明人： Lawrence F. Feinberg ,  Daniel R. Smith ,  Bonnie D. McAvoy ,  Catherine J. Pujol-Baxley ,  Christopher J. Marx

IPC分类号： C12N15/09 ,  C12P23/00 ,  A23K20/179 ,  A23K50/80 ,  A61K9/00 ,  A61K31/122 ,  B01D3/00 ,  C12N15/74

摘要： Non-naturally occurring microorganisms are provided that produce C40 carotenoid compound(s), utilizing exogenously added enzyme activities. Methods of producing C40 carotenoid compounds in microbial cultures, and feed and nutritional supplement compositions that include the C40 carotenoid compounds produced in the microbial cultures, are also provided.

公开(公告)号：US20200224236A1

公开(公告)日：2020-07-16

申请号：US16467471

申请日：2017-12-02

申请人： KnipBio, Inc.

发明人： Lawrence F. Feinberg ,  Daniel R. Smith ,  Martha A. Sholl ,  Sophana Sopha ,  Bonnie D. McAvoy ,  Catherine J. Pujol-Baxley

IPC分类号： C12P21/00 ,  C12N1/20 ,  C12P7/62 ,  A23K10/18 ,  A23K10/12 ,  A23L33/135

摘要： Microorganisms and methods are provided for producing biomass that includes PHB and protein in weight ratios and polymer lengths that are beneficial in feed and nutritional supplement compositions. The compositions also may be used for improvement in feed compositions that improve survivability of livestock and aquaculture species.