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    Controlled, non-linear focused ultrasound treatment
    1.
    发明授权
    Controlled, non-linear focused ultrasound treatment 有权

    公开(公告)号：US10130828B2

    公开(公告)日：2018-11-20

    申请号：US11993443

    申请日：2006-06-19

    申请人： Kobi Vortman ,  Shuki Vitek ,  David Freundlich

    发明人： Kobi Vortman ,  Shuki Vitek ,  David Freundlich

    IPC分类号： A61H1/00 ,  A61N7/02 ,  A61B8/00 ,  A61B8/08 ,  A61B17/22 ,  A61B90/00

    摘要： A system (10) for treating tissue within a body is configured to deliver a first level of ultrasound energy to a target tissue region (42) for a first duration resulting in the generation of micro-bubbles (56) in the target tissue region, determine one or more characteristics of the target tissue region in the presence of the micro-bubbles, and deliver a second level of ultrasound energy to the target tissue region for a second duration, wherein one or both of the second energy level and the second duration are based, at least in part, on the determined one or more characteristics of the target tissue region.

    CONTROLLED, NON-LINEAR FOCUSED ULTRASOUND TREATMENT
    2.
    发明申请
    CONTROLLED, NON-LINEAR FOCUSED ULTRASOUND TREATMENT 审中-公开
    控制，非线性聚焦超声治疗

    公开(公告)号：US20100241036A1

    公开(公告)日：2010-09-23

    申请号：US11993443

    申请日：2006-06-19

    申请人： Kobi Vortman ,  Shuki Vitek ,  David Freundlich

    发明人： Kobi Vortman ,  Shuki Vitek ,  David Freundlich

    IPC分类号： A61N7/02

    CPC分类号： A61N7/02 ,  A61B8/467 ,  A61B8/481 ,  A61B90/37 ,  A61B2017/22008 ,  A61B2090/374 ,  A61B2090/376 ,  A61B2090/378

    摘要： A system (10) for treating tissue within a body is configured to deliver a first level of ultrasound energy to a target tissue region (42) for a first duration resulting in the generation of micro-bubbles (56) in the target tissue region, determine one or more characteristics of the target tissue region in the presence of the micro-bubbles, and deliver a second level of ultrasound energy to the target tissue region for a second duration, wherein one or both of the second energy level and the second duration are based, at least in part, on the determined one or more characteristics of the target tissue region.

    摘要翻译： 用于治疗身体内的组织的系统（10）被配置为将第一级超声能量传递到目标组织区域（42）持续第一持续时间，从而在目标组织区域中产生微气泡（56） 在存在微气泡的情况下确定目标组织区域的一个或多个特征，并且将第二水平的超声能量传递到目标组织区域持续第二持续时间，其中第二能量水平和第二持续时间 至少部分地基于所确定的目标组织区域的一个或多个特征。

    Controlled, non-linear focused ultrasound treatment
    3.
    发明申请
    Controlled, non-linear focused ultrasound treatment 审中-公开
    受控非线性聚焦超声治疗

    公开(公告)号：US20070016039A1

    公开(公告)日：2007-01-18

    申请号：US11158657

    申请日：2005-06-21

    申请人： Kobi Vortman ,  Shuki Vitek ,  David Freundlich

    发明人： Kobi Vortman ,  Shuki Vitek ,  David Freundlich

    IPC分类号： A61B8/00

    CPC分类号： A61N7/02 ,  A61B8/467 ,  A61B8/481 ,  A61B90/37 ,  A61B2017/22008 ,  A61B2090/374 ,  A61B2090/376 ,  A61B2090/378

    摘要： A system for treating tissue within a body is configured to deliver a first level of ultrasound energy to a target tissue region for a first duration resulting in the generation of microbubbles in the target tissue region, determine one or more characteristics of the target tissue region in the presence of the microbubbles, and deliver a second level of ultrasound energy to the target tissue region for a second duration, wherein one or both of the second energy level and the second duration are based, at least in part, on the determined one or more characteristics of the target tissue region.

    摘要翻译： 用于治疗身体内的组织的系统被配置为将第一级超声能量传递到目标组织区域持续第一持续时间，从而在目标组织区域中产生微泡，确定靶组织区域中的一个或多个特征 微泡的存在，并且在第二持续时间内向目标组织区域递送第二水平的超声能量，其中第二能量水平和第二持续时间中的一个或两个至少部分地基于所确定的一个或 目标组织区域的更多特征。

    MAGNETIC RESONANCE THERMOMETRY USING PRF SPECTROSCOPY
    4.
    发明申请
    MAGNETIC RESONANCE THERMOMETRY USING PRF SPECTROSCOPY 审中-公开
    使用PRF光谱的磁共振热分析

    公开(公告)号：US20120071746A1

    公开(公告)日：2012-03-22

    申请号：US13238743

    申请日：2011-09-21

    申请人： Kobi Vortman ,  David Freundlich ,  Shuki Vitek

    发明人： Kobi Vortman ,  David Freundlich ,  Shuki Vitek

    IPC分类号： A61B5/055

    CPC分类号： G01R33/4804 ,  G01R33/4814

    摘要： During the thermal treatment of an anatomical zone of interest, tissue temperature within the zone may be determined with a computational model whose parameters are adjusted using spectroscopy-based temperature measurements at interfaces of fat and non-fat tissues.

    摘要翻译： 在感兴趣的解剖区域的热处理期间，区域内的组织温度可以用计算模型确定，其计算模型的参数使用基于脂肪和非脂肪组织的界面处的基于光谱的温度测量进行调整。

    Focused ultrasound system for surrounding a body tissue mass and treatment method
    6.
    发明授权
    Focused ultrasound system for surrounding a body tissue mass and treatment method 有权
    聚焦超声系统围绕身体组织块和治疗方法

    公开(公告)号：US08409099B2

    公开(公告)日：2013-04-02

    申请号：US10927772

    申请日：2004-08-26

    申请人： Shuki Vitek ,  Kobi Vortman

    发明人： Shuki Vitek ,  Kobi Vortman

    IPC分类号： A61B8/14

    CPC分类号： A61B8/4281 ,  A61B8/0808 ,  A61B8/0825 ,  A61B8/4483 ,  A61B8/4494 ,  A61N7/02 ,  A61N2007/0078 ,  B06B1/0633

    摘要： A focused ultrasound system includes an ultrasound transducer device forming an opening, and having a plurality of transducer elements positioned at least partially around the opening. A focused ultrasound system includes a structure having a first end for allowing an object to be inserted and a second end for allowing the object to exit, and a plurality of transducer elements coupled to the structure, the transducer elements located relative to each other in a formation that at least partially define an opening, wherein the transducer elements are configured to emit acoustic energy that converges at a focal zone.

    摘要翻译： 聚焦超声系统包括形成开口的超声换能器装置，并且具有至少部分地围绕开口定位的多个换能器元件。 聚焦超声系统包括具有用于允许物体被插入的第一端和用于允许物体离开的第二端的结构，以及耦合到该结构的多个换能器元件，换能器元件相对于彼此定位 至少部分地限定开口的形成，其中所述换能器元件被配置为发射在焦点区域会聚的声能。

    Tissue aberration corrections in ultrasound therapy
    8.
    发明授权
    Tissue aberration corrections in ultrasound therapy 有权
    超声治疗组织像差矫正

    公开(公告)号：US08088067B2

    公开(公告)日：2012-01-03

    申请号：US10328584

    申请日：2002-12-23

    申请人： Kobi Vortman ,  Shuki Vitek

    发明人： Kobi Vortman ,  Shuki Vitek

    IPC分类号： A61B8/08

    CPC分类号： A61N7/02 ,  A61B8/0816 ,  A61B8/0858 ,  A61B2090/374 ,  A61B2090/376 ,  A61B2090/378

    摘要： A system for focusing ultrasonic energy through intervening tissue into a target site within a tissue region includes a transducer array including transducer element, an imager for imaging the tissue region, a processor receiving images from the imager to determine boundaries between different tissue types within the intervening tissue and generate correction factors for the transducer elements to compensate for refraction occurring at the boundaries between the tissue types and/or for variations in speed of sound. A controller is coupled to the processor and the transducer array to receive the correction factors and provide excitation signals to the transducer elements based upon the correction factors. The correction factors may include phase and/or amplitude correction factors, and the phases and/or amplitudes of excitation signals provided to the transducer elements may be adjusted based upon the phase correction factors to focus the ultrasonic energy to treat tissue at the target site.

    摘要翻译： 用于将超声波能量通过介入组织聚焦到组织区域内的目标部位的系统包括包括换能器元件的换能器阵列，用于使组织区域成像的成像器，处理器，其从成像器接收图像，以确定在介入区域内的不同组织类型之间的边界 并且产生用于换能器元件的校正因子以补偿在组织类型之间的边界处发生的折射和/或用于声音速度的变化。 控制器耦合到处理器和换能器阵列以接收校正因子，并且基于校正因子向换能器元件提供激励信号。 校正因子可以包括相位和/或幅度校正因子，并且可以基于相位校正因子来调整提供给换能器元件的激励信号的相位和/或幅度，以聚焦超声波能量来在目标部位处理组织。