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公开(公告)号:US11986682B2
公开(公告)日:2024-05-21
申请号:US16314985
申请日:2017-08-03
CPC分类号: A61N7/02 , A61B8/0808 , A61B8/4488 , A61B8/4494 , A61B8/481 , A61B8/585 , A61B2017/00106 , A61B2017/22008 , A61B2090/378 , A61N2007/0039 , A61N2007/0052 , A61N2007/0078 , A61N2007/0095
摘要: Various approaches of focusing an ultrasound transducer having multiple transducer elements to a target region include generating at least one acoustic reflector in the target region; transmitting ultrasound waves to the acoustic reflector; measuring reflections off the acoustic reflector; and based at least in part on the measured reflections, adjusting the parameter value associated with the transducer element(s).
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公开(公告)号:US11272904B2
公开(公告)日:2022-03-15
申请号:US15627922
申请日:2017-06-20
申请人: Kobi Vortman , Shuki Vitek , Yoav Levy
发明人: Kobi Vortman , Shuki Vitek , Yoav Levy
IPC分类号: A61B8/00 , A61B5/01 , A61B5/055 , G01S7/52 , A61B8/08 , A61B17/22 , A61B17/00 , A61B18/00 , A61N7/02 , B06B1/02 , B06B1/06 , A61N7/00 , A61B90/00
摘要: A system for delivering ultrasound energy to an internal anatomical target includes an ultrasound transducer having multiple transducer elements collectively operable as a phased array; multiple driver circuits, each being connected to at least one of the transducer elements; multiple phase circuits; a switch matrix selectably coupling the driver circuits to the phase circuits; and a controller configured for (i) receiving as input a target average intensity level and/or an energy level energy to be applied to the target and/or a temperature level in target, (ii) identifying multiple sets of the transducer elements, each of the sets corresponding to multiple transducer elements for shaping and/or focusing, as a phased array, ultrasound energy at the target across tissue intervening between the target and the ultrasound transducer, and (iii) sequentially operating the transducer-element sets to apply and maintain the target average energy level at the target. In various embodiments, the controller operates each of the transducer element sets in accordance with a pulse-width modulation pattern having a duty cycle selected to achieve the target average intensity level, energy level, and/or temperature level at the target in accordance with a time constant of the target tissue.
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公开(公告)号:US10765892B1
公开(公告)日:2020-09-08
申请号:US15613940
申请日:2017-06-05
申请人: Shuki Vitek , Yoav Levy
发明人: Shuki Vitek , Yoav Levy
IPC分类号: A61N7/00
摘要: Systems and methods for predicting a phase correction of ultrasound waves transmitted from one or more transducer elements and traversing a patient's skull into a target region utilizing data of the patient's skull include predicting a first beam path of the ultrasound waves traversing the skull based at least in part on the target location; computationally determining structural characteristics of the skull along the first beam path based on the acquired imaging data; and predicting a second beam path of the ultrasound waves traversing the skull based at least in part on the determined structural characteristics, thereby accounting for refraction resulting from the skull.
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公开(公告)号:US10677866B1
公开(公告)日:2020-06-09
申请号:US16202558
申请日:2018-11-28
申请人: Shahar Rinott , Yoav Levy
发明人: Shahar Rinott , Yoav Levy
摘要: Systems and methods for performing magnetic resonance (MR) thermometry include a magnetic resonance imaging (MRI) unit and a controller in communication with the MRI unit and configured to cause the MRI unit to acquire one or more baseline phase images of an imaging region and one or more treatment phase images of the imaging region subsequent to a temperature change of a subregion within the imaging region, electronically generate a thermal map pixelwise indicating the temperature change of the subregion based at least in part on the acquired baseline phase image and treatment phase image, computationally predict the temperature change of the subregion based at least in part on energy deposited in the subregion during treatment without reference to the generated thermal map, and determine whether the thermal map is inaccurate based at least in part on the temperature change of the subregion indicated by the thermal map and the predicted temperature change of the subregion.
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公开(公告)号:US10589129B2
公开(公告)日:2020-03-17
申请号:US15265204
申请日:2016-09-14
申请人: Kobi Vortman , Shuki Vitek , Eyal Zadicario , Yoav Levy
发明人: Kobi Vortman , Shuki Vitek , Eyal Zadicario , Yoav Levy
摘要: Various approaches for reducing microbubble interference with ultrasound waves transmitted from multiple transducer elements and traversing tissue onto a target region include measuring microbubbles in high-throughput areas of ultrasound exposure and reducing the amount of microbubbles using the ultrasound waves.
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公开(公告)号:US20190001154A1
公开(公告)日:2019-01-03
申请号:US15637163
申请日:2017-06-29
申请人: Kobi VORTMAN , Yoav LEVY
发明人: Kobi VORTMAN , Yoav LEVY
IPC分类号: A61N5/10
摘要: An approach for enhancing radiation treatment of target tissue includes identifying a target volume of the target tissue; causing disruption of vascular tissue in a region confined to the target volume so as to define the target volume; based at least in part on the disruption of the vascular tissue, determining a radiation treatment plan having a reduced radiation dose for treating the target tissue; and exposing the target volume to the reduced radiation dose based on the radiation treatment plan.
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公开(公告)号:US20180206816A1
公开(公告)日:2018-07-26
申请号:US15415351
申请日:2017-01-25
摘要: Various approaches for detecting microbubble cavitation resulting from ultrasound waves transmitted from an ultrasound transducer include associating at least one time-domain reference signal with microbubble cavitation; causing the transducer to transmit one or more ultrasound pulse; acquiring, in the time domain, an echo signal from microbubbles in response to the transmitted ultrasound pulse(s); correlating at least a portion of the echo signal to at least a corresponding portion of the time-domain reference signal based on similarity therebetween; and detecting the microbubble cavitation based on the corresponding portion of the reference signal.
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公开(公告)号:US09814909B2
公开(公告)日:2017-11-14
申请号:US14377062
申请日:2013-02-06
申请人: INSIGHTEC, LTD. , Yoav Levy , Yoav Medan , Kobi Vortman
发明人: Yoav Levy , Yoav Medan , Kobi Vortman
IPC分类号: G06K9/00 , A61N7/00 , A61B5/055 , A61N7/02 , G06T7/73 , G06T7/246 , A61B5/01 , A61B17/00 , A61B90/00
CPC分类号: A61N7/00 , A61B5/015 , A61B5/055 , A61B2017/00084 , A61B2090/374 , A61N7/02 , A61N2007/0056 , F04C2270/041 , G06T7/248 , G06T7/74 , G06T2207/10088 , G06T2207/10132 , G06T2207/30004 , G06T2207/30096
摘要: During a focused-ultrasound or other non-invasive treatment procedure, the motion of the treatment target or other object(s) of interest can be tracked in real time based on the comparison of treatment images against a reference library of images that have been acquired prior to treatment for the anticipated range of motion and have been processed to identify the location of the target or other object(s) therein.
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公开(公告)号:US20150359603A1
公开(公告)日:2015-12-17
申请号:US14763684
申请日:2014-01-29
申请人: Yoav LEVY , Benny ASSIF , Gilad HALEVY , Yoni HERTZBERG , INSIGHTEC, LTD.
发明人: Yoav Levy , Benny Assif , Gilad Halevy , Yoni Hertzberg
摘要: A focused-ultrasound or other procedure for treating a target within a tissue region can be planned iteratively by creating a treatment plan specifying a treatment location pattern and stimuli applied thereto, simulating the treatment, computationally predicting an effect of the simulated treatment, comparing the predicted effect against one or more treatment constraints (such as efficacy and/or safety thresholds), and, if a constraint is violated, repeating the simulation for an adjusted treatment plan.
摘要翻译: 可以通过创建指定治疗位置模式和施加到其上的刺激的治疗计划来迭代地计划用于治疗组织区域内的靶的聚焦超声或其它程序,模拟治疗,计算地预测模拟治疗的效果,比较预测 对于一个或多个治疗约束(例如功效和/或安全阈值)的效果,并且如果违反约束,则重复经调整的治疗计划的模拟。
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公开(公告)号:US08804533B2
公开(公告)日:2014-08-12
申请号:US12979587
申请日:2010-12-28
申请人: Yuri Podlyas , Gil Benamar , Yoav Levy , Doron Tal
发明人: Yuri Podlyas , Gil Benamar , Yoav Levy , Doron Tal
CPC分类号: H04W76/12
摘要: A method for acceleration of wireless communication in a residential gateway, the residential gateway enables communication between a plurality of subscriber devices connected in a wireless local area network (WLAN) and a passive optical network (PON). The method comprises pre-configuring a wireless controller to intercept networking functions programmed in a wireless stack of a wireless driver, wherein the wireless controller and the wireless driver are components of a kernel of an operating system executed by a host processor; monitoring system calls initiated by the wireless driver to the kernel; for each monitored system call, checking if a system call is a request for a networking function; and forwarding the system call for a network function to a packet processor.
摘要翻译: 一种用于在住宅网关中加速无线通信的方法,住宅网关实现了连接在无线局域网(WLAN)和无源光网络(PON)之间的多个用户设备之间的通信。 该方法包括预先配置无线控制器以拦截在无线驱动器的无线堆栈中编程的网络功能,其中无线控制器和无线驱动器是由主处理器执行的操作系统的内核的组件; 将无线驱动程序发起的监控系统呼叫发送到内核; 对于每个被监视的系统调用,检查系统调用是否是对联网功能的请求; 并将用于网络功能的系统调用转发到分组处理器。
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