公开(公告)号：US20110285838A1

公开(公告)日：2011-11-24

申请号：US13102232

申请日：2011-05-06

申请人： Koichiro Kishima ,  Gakuho Fukushi ,  Ryu Narusawa

发明人： Koichiro Kishima ,  Gakuho Fukushi ,  Ryu Narusawa

IPC分类号： H04N5/247 ,  H04N7/18

CPC分类号： G02B21/367 ,  H04N1/3876

摘要： Provided is an information processing apparatus including a first setting unit and a second setting unit. The first setting unit sets position coordinates of first photography regions arranged along a first direction of two orthogonal axial directions so that the first photography regions adjacent to each other have first overlapping regions where the first photography regions overlap with each other in the first direction. The second setting unit sets position coordinates of second photography regions arranged along the first direction based on the position coordinates of the first photography regions so that the second photography regions adjacent to each other have second overlapping regions where the second photography regions overlap with each other in the first direction, the second photography regions overlap with the first photography regions in a second direction of the two axial directions, and the second overlapping regions are prevented from overlapping with the first overlapping regions.

摘要翻译： 提供了一种包括第一设定单元和第二设定单元的信息处理设备。 第一设定单元设置沿着两个正交轴方向的第一方向布置的第一拍摄区域的位置坐标，使得彼此相邻的第一拍摄区域具有第一拍摄区域在第一方向上彼此重叠的第一重叠区域。 第二设定单元基于第一拍摄区域的位置坐标来设置沿着第一方向布置的第二摄影区域的位置坐标，使得彼此相邻的第二摄影区域具有第二拍摄区域彼此重叠的第二重叠区域 第一方向，第二摄影区域在两个轴向的第二方向上与第一摄影区域重叠，并且防止第二重叠区域与第一重叠区域重叠。

公开(公告)号：US20120016230A1

公开(公告)日：2012-01-19

申请号：US13178155

申请日：2011-07-07

申请人： Koichiro Kishima ,  Tetsumasa Yonemitsu ,  Gakuho Fukushi

发明人： Koichiro Kishima ,  Tetsumasa Yonemitsu ,  Gakuho Fukushi

IPC分类号： A61B6/00

CPC分类号： A61B5/0071 ,  A61B1/00186 ,  A61B1/00188 ,  A61B1/002 ,  A61B1/042 ,  A61B1/043 ,  A61B1/045 ,  A61B1/0638 ,  A61B1/0646 ,  A61B5/0086 ,  A61B5/415 ,  A61B5/418

摘要： An imaging apparatus includes: a first illumination unit to apply visible light to a subject having a fluorescent substance; a second illumination unit to apply excitation light to the subject so that fluorescence is generated from the fluorescent substance; an optical filter unit to cause the visible light and the fluorescence to pass therethrough, and shield the excitation light; an imaging unit including imaging elements to generate image signals, and an output unit to read the image signals from the imaging elements and output image information; an optical element to divide the visible light into component light beams, cause the divided light beams to be incident on the imaging elements, and cause the fluorescence to be incident on at least one imaging element; and a control means for alternately applying the visible light and the excitation light and alternately outputting image information of the visible light and the fluorescence.

摘要翻译： 一种成像设备包括：第一照明单元，用于向具有荧光物质的对象施加可见光; 第二照明单元，用于向所述对象施加激发光，使得从所述荧光物质产生荧光; 用于使可见光和荧光通过的光学滤光器单元，并遮蔽激发光; 成像单元，其包括用于生成图像信号的成像元件;以及输出单元，用于从成像元件读取图像信号并输出​​图像信息; 用于将可见光分割为分量光束的光学元件使得分割的光束入射到成像元件上，并使荧光入射到至少一个成像元件上; 以及用于交替地施加可见光和激发光并交替地输出可见光和荧光的图像信息的控制装置。

公开(公告)号：US08675970B2

公开(公告)日：2014-03-18

申请号：US13159839

申请日：2011-06-14

申请人： Gakuho Fukushi ,  Koichiro Kishima

发明人： Gakuho Fukushi ,  Koichiro Kishima

IPC分类号： G06K9/48

CPC分类号： G06K9/3233 ,  G06K9/0014 ,  G06K9/4604

摘要： An image processing apparatus including: an edge detection processing section configured to generate an edge image by performing edge detection processing on a detection target image from which a target object is to be detected; a segment area setting section configured to segmentalize the edge image into a plurality of segment areas; an index value calculation section configured to calculate, for each of the plurality of segment areas, an edge component index value that indicates an amount of edge components included in each segment area; and a target object determining section configured to determine whether there is an image of the target object in each segment area based on the edge component index value.

摘要翻译： 一种图像处理装置，包括：边缘检测处理部，被配置为通过对要检测目标对象的检测对象图像执行边缘检测处理来生成边缘图像; 段区域设定部，被构成为将边缘图像分割为多个片段区域; 指标值计算部，被配置为针对所述多个分段区域中的每一个计算表示包括在每个分段区域中的边缘分量的边缘分量指标值; 以及目标对象确定部，其被配置为基于所述边缘分量索引值来确定在每个分段区域中是否存在所述目标对象的图像。

公开(公告)号：US20110317924A1

公开(公告)日：2011-12-29

申请号：US13159839

申请日：2011-06-14

申请人： Gakuho Fukushi ,  Koichiro Kishima

发明人： Gakuho Fukushi ,  Koichiro Kishima

IPC分类号： G06K9/48

CPC分类号： G06K9/3233 ,  G06K9/0014 ,  G06K9/4604

摘要： An image processing apparatus including: an edge detection processing section configured to generate an edge image by performing edge detection processing on a detection target image from which a target object is to be detected; a segment area setting section configured to segmentalize the edge image into a plurality of segment areas; an index value calculation section configured to calculate, for each of the plurality of segment areas, an edge component index value that indicates an amount of edge components included in each segment area; and a target object determining section configured to determine whether there is an image of the target object in each segment area based on the edge component index value.

摘要翻译： 一种图像处理装置，包括：边缘检测处理部，被配置为通过对要检测目标对象的检测对象图像执行边缘检测处理来生成边缘图像; 段区域设定部，被构成为将边缘图像分割为多个片段区域; 指标值计算部，被配置为针对所述多个分段区域中的每一个计算表示包括在每个分段区域中的边缘分量的边缘分量指标值; 以及目标对象确定部，其被配置为基于所述边缘分量索引值来确定在每个分段区域中是否存在所述目标对象的图像。

公开(公告)号：US09100532B2

公开(公告)日：2015-08-04

申请号：US13159067

申请日：2011-06-13

申请人： Ryu Narusawa ,  Koichiro Kishima

发明人： Ryu Narusawa ,  Koichiro Kishima

IPC分类号： H04N9/083 ,  H04N3/14 ,  H04N5/335 ,  H04N9/04 ,  H04N5/228 ,  H04N9/73

CPC分类号： H04N9/045 ,  H04N9/735

摘要： An image processing apparatus includes an output signal obtaining unit that is connected to a pixel group having a first pixel, a second pixel, and a third pixel and obtains a first output signal, a second output signal, and a third output signal, a spectral sensitivity determination unit that determines a first spectral sensitivity, a second spectral sensitivity, and a third spectral sensitivity, which are spectral sensitivities of the first, second, and third output signals, respectively, with respect to a wavelength of incident light entering the pixel group, an output signal amplification unit that amplifies the first, second, and third output signals based on the first, second, and third spectral sensitivities, respectively, and an image generation unit calculates pixel values of the first pixel, the second pixel, and the third pixel from the first output signal, the second output signal, and the third output signal amplified, and generates an image.

摘要翻译： 一种图像处理装置，包括输出信号获取单元，其连接到具有第一像素，第二像素和第三像素的像素组，并获得第一输出信号，第二输出信号和第三输出信号，光谱 灵敏度确定单元，其分别确定第一，第二和第三输出信号相对于入射到像素组的入射光的波长的光谱灵敏度，第二光谱灵敏度和第三光谱灵敏度 输出信号放大单元，其分别基于第一，第二和第三光谱灵敏度放大第一，第二和第三输出信号，并且图像生成单元计算第一像素，第二像素和 从第一输出信号，第二输出信号和第三输出信号放大第三像素，并产生图像。

公开(公告)号：US08598541B2

公开(公告)日：2013-12-03

申请号：US12868187

申请日：2010-08-25

申请人： Koichiro Kishima ,  Yu Hirono ,  Nobuhiro Hayashi ,  Takamichi Yamakoshi ,  Nobuhiro Kihara ,  Takashi Yamamoto ,  Fumiyasu Suzuki ,  Ryu Narusawa

发明人： Koichiro Kishima ,  Yu Hirono ,  Nobuhiro Hayashi ,  Takamichi Yamakoshi ,  Nobuhiro Kihara ,  Takashi Yamamoto ,  Fumiyasu Suzuki ,  Ryu Narusawa

IPC分类号： G01J1/58

CPC分类号： G01N21/6458 ,  G01N21/6428

摘要： A fluorescent image obtaining device includes a light source that irradiates light such that a fluorescent material marked on a target in a biological sample lies in a non-excited state and a fluorescent material marked on a control with the target lies in an excited state, and an imaging unit that takes an image including the entire biological sample.

摘要翻译： 荧光图像获取装置包括照射光的光源，使得标记在生物样品中的靶上的荧光物质处于非激发状态，并且标记在靶上的荧光材料处于激发状态，并且 拍摄包含整个生物样品的图像的成像单元。

公开(公告)号：US09386233B2

公开(公告)日：2016-07-05

申请号：US13617418

申请日：2012-09-14

申请人： Koichiro Kishima ,  Ryu Narusawa ,  Fumiyasu Suzuki

发明人： Koichiro Kishima ,  Ryu Narusawa ,  Fumiyasu Suzuki

IPC分类号： H04N5/235 ,  G02B21/36

CPC分类号： H04N5/2356 ,  G02B21/367

摘要： An image acquisition apparatus includes an optical system, an imaging device, a movement controller, and a multiple exposure processing unit. The optical system includes an objective lens for magnifying a portion of an imaging target. The imaging device is capable of performing all-pixel simultaneous exposure and is configured to image the portion magnified by the optical system. The movement controller is configured to move a focal point of the objective lens in a thickness direction of the portion of the imaging target. The multiple exposure processing unit is configured to perform multiple exposure of the imaging device at a plurality of positions such that, for each of ranges sectioned by positions in a direction in which the focal point is movable, an average image that covers each of the ranges is obtained.

摘要翻译： 图像采集装置包括光学系统，成像装置，移动控制器和多曝光处理单元。 光学系统包括用于放大成像目标的一部分的物镜。 成像装置能够执行全像素同时曝光，并且被配置为对由光学系统放大的部分进行成像。 移动控制器被配置为沿着成像目标的该部分的厚度方向移动物镜的焦点。 多重曝光处理单元被配置为在多个位置执行成像装置的多次曝光，使得对于通过焦点可移动的方向上的位置分割的每个范围，覆盖每个范围的平均图像 获得。

公开(公告)号：US20110317058A1

公开(公告)日：2011-12-29

申请号：US13159067

申请日：2011-06-13

申请人： Ryu Narusawa ,  Koichiro Kishima

发明人： Ryu Narusawa ,  Koichiro Kishima

IPC分类号： H04N9/07

CPC分类号： H04N9/045 ,  H04N9/735

摘要： An image processing apparatus includes an output signal obtaining unit that is connected to a pixel group having a first pixel, a second pixel, and a third pixel and obtains a first output signal, a second output signal, and a third output signal, a spectral sensitivity determination unit that determines a first spectral sensitivity, a second spectral sensitivity, and a third spectral sensitivity, which are spectral sensitivities of the first, second, and third output signals, respectively, with respect to a wavelength of incident light entering the pixel group, an output signal amplification unit that amplifies the first, second, and third output signals based on the first, second, and third spectral sensitivities, respectively, and an image generation unit calculates pixel values of the first pixel, the second pixel, and the third pixel from the first output signal, the second output signal, and the third output signal amplified, and generates an image.

摘要翻译： 一种图像处理装置，包括输出信号获取单元，其连接到具有第一像素，第二像素和第三像素的像素组，并获得第一输出信号，第二输出信号和第三输出信号，光谱 灵敏度确定单元，其分别确定第一，第二和第三输出信号相对于入射到像素组的入射光的波长的光谱灵敏度，第二光谱灵敏度和第三光谱灵敏度 输出信号放大单元，其分别基于第一，第二和第三光谱灵敏度放大第一，第二和第三输出信号，并且图像生成单元计算第一像素，第二像素和 从第一输出信号，第二输出信号和第三输出信号放大第三像素，并产生图像。

公开(公告)号：US09110306B2

公开(公告)日：2015-08-18

申请号：US12862220

申请日：2010-08-24

申请人： Nobuhiro Hayashi ,  Koichiro Kishima ,  Takashi Yamamoto ,  Nobuhiro Kihara ,  Takamichi Yamakoshi ,  Fumiyasu Suzuki ,  Ryu Narusawa

发明人： Nobuhiro Hayashi ,  Koichiro Kishima ,  Takashi Yamamoto ,  Nobuhiro Kihara ,  Takamichi Yamakoshi ,  Fumiyasu Suzuki ,  Ryu Narusawa

IPC分类号： G06K9/00 ,  G02B21/36 ,  G06K9/32 ,  G06T7/00 ,  G01N1/31 ,  G02B21/34

CPC分类号： G02B21/367 ,  G01N1/312 ,  G02B21/34 ,  G06K9/00134 ,  G06K9/3216 ,  G06K9/3233 ,  G06T7/11 ,  G06T7/174 ,  G06T2207/10056 ,  G06T2207/30024

摘要： A tissue-slice image acquirement and display apparatus includes: an entire-image acquirer that acquires a bright-field image of an entirety of a first slice of a tissue and a dark-field image of an entirety of a second slice of the tissue; a modifier that modifies a profile shape of a slice portion in the dark-field image on the basis of a profile shape of a slice portion in the bright-field image; a magnified-image acquirer that determines a range encompassing the second slice on the basis of the profile shape of the modified slice portion and that acquires, in a dark field, a magnified image of the second slice in the determined range; and a display controller that causes the bright-field image to be displayed and that causes a portion of the magnified image, the portion corresponding to a position selected in the bright-field image, to be displayed.

摘要翻译： 组织切片图像获取和显示装置包括：整体图像获取器，其获取组织的第一切片的整体的亮场图像和组织的第二切片的整体的暗视场图像; 基于亮场图像中的切片部分的轮廓形状来修改暗视场图像中的切片部分的轮廓形状的修改器; 放大图像获取器，其基于修改的切片部分的轮廓形状确定包围第二切片的范围，并且在暗场中获取在所确定的范围内的第二切片的放大图像; 以及显示控制器，其使亮域图像被显示，并且使得显示放大图像的一部分，与亮域图像中选择的位置对应的部分。

公开(公告)号：US20110049389A1

公开(公告)日：2011-03-03

申请号：US12868187

申请日：2010-08-25

申请人： Koichiro Kishima ,  Yu Hirono ,  Nobuhiro Hayashi ,  Takamichi Yamakoshi ,  Nobuhiro Kihara ,  Takashi Yamamoto ,  Fumiyasu Suzuki ,  Ryu Narusawa

发明人： Koichiro Kishima ,  Yu Hirono ,  Nobuhiro Hayashi ,  Takamichi Yamakoshi ,  Nobuhiro Kihara ,  Takashi Yamamoto ,  Fumiyasu Suzuki ,  Ryu Narusawa

IPC分类号： G01J1/58

CPC分类号： G01N21/6458 ,  G01N21/6428

摘要： A fluorescent image obtaining device includes a light source that irradiates light such that a fluorescent material marked on a target in a biological sample lies in a non-excited state and a fluorescent material marked on a control with the target lies in an excited state, and an imaging unit that takes an image including the entire biological sample.

摘要翻译： 荧光图像获取装置包括照射光的光源，使得标记在生物样品中的靶上的荧光物质处于非激发状态，并且标记在靶上的荧光材料处于激发状态，并且 拍摄包含整个生物样品的图像的成像单元。