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25 条记录 (耗时 0.023 秒)

    Novel ethyl benzylphosphinate derivatives, process for production thereof, and their use as calcium antagonist
    1.
    发明授权
    Novel ethyl benzylphosphinate derivatives, process for production thereof, and their use as calcium antagonist 失效
    新型乙基苄基次膦酸盐衍生物，其制备方法及其作为钙拮抗剂的用途

    公开(公告)号：US4607031A

    公开(公告)日：1986-08-19

    申请号：US737037

    申请日：1985-05-22

    申请人： Koichiro Yoshino ,  Tominori Morita ,  Masaru Moriyama ,  Keizo Ito ,  Goro Tsukamoto

    发明人： Koichiro Yoshino ,  Tominori Morita ,  Masaru Moriyama ,  Keizo Ito ,  Goro Tsukamoto

    IPC分类号： C07F9/6558 ,  A61K31/675 ,  C07F9/65

    CPC分类号： C07F9/65583

    摘要： An ethyl benzylphosphinate derivative represented by the general formula (I) ##STR1## wherein Y represents a hydrogen or fluorine atom, X represents a methylene group or an oxygen atom, and n is 2, 3 or 4.The said compounds can be produced by reacting a compound represented by the following formula (II) ##STR2## wherein Y is as defined above, with a compound represented by the following formula (III) ##STR3## wherein X and n are as defined, and M is an alkali metal atom, in an inert medium. These compounds are useful as a calcium antagonist.

    摘要翻译： 由通式（I）表示的乙基苄基次膦酸盐衍生物其中Y表示氢或氟原子，X表示亚甲基或氧原子，n为2,3或4.所述化合物可以 通过使下式（II）表示的化合物（其中Y如上定义）与由下式（III）表示的化合物（III）反应制备：其中X和n为 并且在惰性介质中M是碱金属原子。 这些化合物可用作钙拮抗剂。

    Novel 4,5-Bis (4-methoxyphenyl)-2-(pyrrol-2-yl) thiazoles and pharmaceutical composition containing the same
    4.
    发明授权
    Novel 4,5-Bis (4-methoxyphenyl)-2-(pyrrol-2-yl) thiazoles and pharmaceutical composition containing the same 失效
    新的4,5-双（4-甲氧基苯基）-2-（吡咯-2-基）噻唑和含有它们的药物组合物

    公开(公告)号：US4659726A

    公开(公告)日：1987-04-21

    申请号：US722322

    申请日：1985-04-12

    申请人： Koichiro Yoshino ,  Norihiko Seko ,  Koichi Yokota ,  Keizo Ito ,  Goro Tsukamoto

    发明人： Koichiro Yoshino ,  Norihiko Seko ,  Koichi Yokota ,  Keizo Ito ,  Goro Tsukamoto

    IPC分类号： C07D207/34 ,  C07D417/04 ,  A61K31/425 ,  C07D277/24 ,  C07D277/28

    CPC分类号： C07D417/04 ,  C07D207/34

    摘要： Novel 4,5-bis(4-methoxyphenyl)-2-(pyrrol-2-yl)-thiazoles of the formula: ##STR1## wherein R.sup.1 is C.sub.1-4 alkyl, C.sub.2-4 alkenyl, C.sub.2-4 alkynyl, 2,2,2-trifluoroethyl, a group of the formula: --CH.sub.2 COOR.sup.2 R.sup.2 is C.sub.1-8 alkyl, C.sub.2-4 alkenyl, C.sub.2-4 alkynyl, or phenyl-C.sub.1-2 alkyl), or a group of the formula: --(CH.sub.2).sub.n --A--R.sup.3 (A is oxygen or sulfur, R.sup.3 is C.sub.1-4 alkyl or C.sub.2-4 alkenyl, and n is 1, 2 or 3), a process for the preparation of the compounds, and a pharmaceutical composition useful as a platelet aggregation inhibitor which comprises as an active ingredient the above 4,5-bis(4-methoxyphenyl)-2-(pyrrol-2-yl)thiazole compound in admixture with a conventional pharmaceutically acceptable carrier or diluent.

    摘要翻译： 具有下式的新的4,5-双（4-甲氧基苯基）-2-（吡咯-2-基） - 噻唑其中R 1是C 1-4烷基，C 2-4烯基，C 2-4炔基 ，2,2,2-三氟乙基，式-CH 2 COOR 2 R 2的基团是C 1-8烷基，C 2-4烯基，C 2-4炔基或苯基-C 1-2烷基）或下式的基团： - （CH 2）n A -R 3（A是氧或硫，R 3是C 1-4烷基或C 2-4链烯基，n是1,2或3），化合物的制备方法和有用的药物组合物 作为血小板聚集抑制剂，其与常规药学上可接受的载体或稀释剂混合包含作为活性成分的上述4,5-双（4-甲氧基苯基）-2-（吡咯-2-基）噻唑化合物。

    Image processing device, image signal correction method, correction matrix calculation method, and imaging device
    7.
    发明授权
    Image processing device, image signal correction method, correction matrix calculation method, and imaging device 有权
    图像处理装置，图像信号校正方法，校正矩阵计算方法和成像装置

    公开(公告)号：US08692910B2

    公开(公告)日：2014-04-08

    申请号：US12835953

    申请日：2010-07-14

    申请人： Koichiro Yoshino

    发明人： Koichiro Yoshino

    IPC分类号： H04N9/64

    CPC分类号： H04N9/045 ,  H04N9/67 ,  H04N17/002

    摘要： Provided is an imaging device that is equipped with an image acquisition element having color filters in prescribed arrays; a judgment unit that judges to which group individual pixels of a color image belong, the group being a group among a plurality of groups determined in accordance with the arrangement of color filters, and the color image being an image generated based on output signals from the image acquisition element; a storage unit in which the groups are stored in association with correction matrices; and a correction unit that obtains the correction matrices corresponding to groups to which each of the pixels belongs from the storage unit and that corrects the image signal values of individual pixels by using the obtained correction matrices.

    摘要翻译： 提供了一种成像装置，其配备有具有规定阵列的滤色器的图像采集元件; 判断单元，其判断彩色图像属于哪个组的各个像素，所述组是根据滤色器的布置确定的多个组中的组，并且所述彩色图像是基于来自所述彩色滤波器的输出信号生成的图像 图像采集元件; 存储单元，其中所述组与校正矩阵相关联地存储; 以及校正单元，其从存储单元获得与每个像素所属的组相对应的校正矩阵，并且通过使用获得的校正矩阵来校正各个像素的图像信号值。

    IMAGING APPARATUS, ENDOSCOPE APPARATUS, AND IMAGE GENERATION METHOD
    8.
    发明申请
    IMAGING APPARATUS, ENDOSCOPE APPARATUS, AND IMAGE GENERATION METHOD 审中-公开
    成像装置，内窥镜装置和图像生成方法

    公开(公告)号：US20120105612A1

    公开(公告)日：2012-05-03

    申请号：US13253389

    申请日：2011-10-05

    申请人： Koichiro Yoshino

    发明人： Koichiro Yoshino

    IPC分类号： H04N5/232 ,  H04N7/18

    CPC分类号： A61B1/00009 ,  A61B1/00163 ,  A61B1/00188

    摘要： An imaging apparatus includes an image acquisition section, an exposure adjustment section, and a synthetic image generation section. The image acquisition section acquires a near point image in which a near-point object is in focus, and a far point image in which a far-point object positioned away as compared with the near-point object is in focus. The exposure adjustment section adjusts the ratio of the exposure of the near point image to the exposure of the far point image. The synthetic image generation section generates a synthetic image based on the near point image and the far point image acquired with exposure for which the ratio is adjusted.

    摘要翻译： 成像装置包括图像获取部分，曝光调整部分和合成图像生成部分。 图像获取部获取近点对象被聚焦的近点图像，并且与近点对象相比位于远处的远点对象位于焦点的远点图像。 曝光调整部调整近点图像的曝光与远点图像的曝光的比例。 合成图像生成部基于通过调整比例的曝光获取的近点图像和远点图像来生成合成图像。

    Capsule endoscope
    9.
    发明申请
    Capsule endoscope 有权
    胶囊内窥镜

    公开(公告)号：US20050054901A1

    公开(公告)日：2005-03-10

    申请号：US10933314

    申请日：2004-09-03

    申请人： Koichiro Yoshino

    发明人： Koichiro Yoshino

    IPC分类号： A61B1/00 ,  A61B1/05 ,  A61B1/273 ,  A61B1/31 ,  G02B13/00 ,  G02B23/24

    CPC分类号： A61B1/041 ,  A61B1/00096 ,  A61B1/00188 ,  A61B1/2733 ,  A61B1/31 ,  G02B23/2423

    摘要： A capsule endoscope is disclosed that includes a capsule and a transparent cover having a central axis and that is located in front of an objective optical system within the capsule. The objective optical system has a depth of field, a field of view, and an image surface that has curvature of field, and is arranged on the central axis of the transparent cover and the capsule. The field of view of the objective optical system includes a spherical surface that is tangent to the transparent cover at a periphery of the field of view, and the near point of the depth of field on the optical axis of the objective optical system is positioned farther from the objective optical system than is the transparent cover. Various conditions are satisfied so as to provide high quality imaging.

    摘要翻译： 公开了一种胶囊型内窥镜，其包括胶囊和具有中心轴线并且位于胶囊内的物镜光学系统前方的透明盖。 物镜光学系统具有景深，视野和具有曲率的图像面，并且布置在透明盖和胶囊的中心轴上。 物镜光学系统的视野包括在视场周边与透明盖相切的球面，并且物镜光学系统的光轴上的景深近点位于更远处 从物镜光学系统比透明盖。 满足各种条件以提供高质量的成像。

    Method for decarbonization refining of chromium-containing molten steel
    10.
    发明授权
    Method for decarbonization refining of chromium-containing molten steel 有权
    含铬钢水脱碳精炼方法

    公开(公告)号：US06830606B2

    公开(公告)日：2004-12-14

    申请号：US10482560

    申请日：2003-12-30

    申请人： Ryuji Nakao ,  Tomoaki Tanaka ,  Masao Igarashi ,  Koichiro Yoshino

    发明人： Ryuji Nakao ,  Tomoaki Tanaka ,  Masao Igarashi ,  Koichiro Yoshino

    IPC分类号： C21C7068

    CPC分类号： C21C7/0685 ,  C21B5/001 ,  C21C5/005 ,  C21C5/4673 ,  C21C7/072 ,  C21C7/10 ,  C21C2300/06 ,  Y02P10/286 ,  Y10S706/904

    摘要： The present invention: solves the problems of hitherto disclosed technologies, such as insufficient suppression of the oxidation loss of [Cr] and the excessive erosion of refractories, in the decarburization-refining of chromium-contained molten steel under a normal or reduced pressure; and is characterized by: determining, in sequence; a molten steel temperature during the refining through actual measurement or computation from a molten steel temperature before the refining and refining conditions; [C] and [Cr] concentrations during the refining through actual measurement or computation from molten steel components before the refining and refining conditions; a CO partial pressure PCO in an atmosphere during the refining from the total pressure P of the atmosphere, an oxygen gas supply rate and an inert gas supply rate, a Hilty's equilibrium temperature TH from said [C] and [Cr] concentrations and PCO; the difference &Dgr;T between said molten steel temperature during the refining and said Hilty's equilibrium temperature TH: and controlling the refining conditions so that said &Dgr;T is equal to a prescribed value or higher.

    摘要翻译： 本发明解决了在正常或减压下含铬钢水的脱碳精炼中迄今为止公开的技术的诸如不充分抑制[Cr]的氧化损失和耐火材料过度侵蚀的技术的问题; 其特征在于：依次确定 精炼过程中的钢水温度在精炼和精炼条件之前由钢水温度进行实际测量或计算; 在精炼过程中，通过在精炼和精炼条件之前从钢水部件进行实际测量或计算，精炼中的[C]和[Cr]浓度; 来自大气的总压力P的精炼期间的气氛中的CO分压PCO，氧气供给速率和惰性气体供给速率，来自所述[C]和[Cr]浓度和PCO的Hilty的平衡温度TH; 在精炼期间的所述钢水温度与所述Hilty的平衡温度TH之间的差ΔTt，并控制精炼条件使得所述ΔT等于或等于规定值以上。