公开(公告)号：US11286454B2

公开(公告)日：2022-03-29

申请号：US15756029

申请日：2016-08-30

申请人： I PEACE, INC. ,  Koji Tanabe

发明人： Koji Tanabe ,  Brendan Kelly ,  Kenta Suto

IPC分类号： C12M1/36 ,  C12M1/00 ,  C12M1/34 ,  C12M1/33 ,  C12M1/42 ,  C12N5/078 ,  C12M3/00 ,  C12M1/02 ,  C12M1/12 ,  C12N5/074

摘要： The present invention provides a stem cell manufacturing system comprising: a sending channel (20) through which a solution containing cells flows; an apparatus (30) which is connected to the sending channel (20) and transfers a pluripotency inducer into the cells to produce cells harboring the inducer; and an apparatus (40) which cultures the cells harboring the inducer to produce cell clusters consisting of stem cells.

公开(公告)号：US10508260B2

公开(公告)日：2019-12-17

申请号：US16299048

申请日：2019-03-11

申请人： I Peace, Inc. ,  Koji Tanabe

发明人： Koji Tanabe ,  Brendan Kelly ,  Kenta Suto ,  Hidenori Shimoda ,  Ryoji Hiraide

IPC分类号： C12M1/00 ,  C12M1/36 ,  C12M1/42 ,  C12M1/33 ,  C12N5/074 ,  C12M1/12 ,  C12M3/00 ,  C12N5/078 ,  C12M1/34 ,  C12M1/02

摘要： A cell mass dissociator for a pluripotent stem cell production system.

公开(公告)号：US11912977B2

公开(公告)日：2024-02-27

申请号：US17817287

申请日：2022-08-03

申请人： I Peace, Inc. ,  Koji Tanabe

发明人： Koji Tanabe ,  Brendan Kelly ,  Kenta Suto ,  Hidenori Shimoda ,  Ryoji Hiraide

IPC分类号： C12N5/074 ,  C12M1/36 ,  C12M1/00 ,  C12M1/34 ,  C12M1/33 ,  C12M1/42 ,  C12N5/078 ,  C12M3/00 ,  C12M1/02 ,  C12M1/12

CPC分类号： C12M41/48 ,  C12M23/28 ,  C12M23/44 ,  C12M27/00 ,  C12M29/00 ,  C12M29/04 ,  C12M35/00 ,  C12M37/02 ,  C12M41/12 ,  C12M41/36 ,  C12M45/02 ,  C12M47/04 ,  C12N5/0634 ,  C12N5/0696

摘要： A stem cell production system provided with a preintroduction cell-feeding solution channel 20 through which a solution containing cells passes, an induction factor-feeding solution mechanism 21 for feeding a pluripotency induction factor to the preintroduction cell-feeding solution channel 20, a factor introduction device 30 connected to the preintroduction cell-feeding solution channel 20 for making cells with induction factor introduced by introducing the pluripotency induction factor into the cells, a cell mass-making device 40 for making multiple cell masses comprising stem cells by culturing the cells with induction factor introduced, and a packaging device 100 for sequentially packaging each of the multiple cell masses.

公开(公告)号：US20230030031A1

公开(公告)日：2023-02-02

申请号：US17934953

申请日：2022-09-23

申请人： Koji Tanabe ,  I Peace, Inc.

发明人： Koji Tanabe ,  Kenta Suto ,  Ryoji Hiraide

IPC分类号： C12M1/34 ,  C12M1/00 ,  C12N5/0735

摘要： This cell treatment device is provided with: a factor introduction device 30 for introducing a pluripotent induction factor into cells so as to prepare induction factor-introduced cells; and a reprogramming suspension culture vessel for culturing the induction factor-introduced cells that have been prepared by the factor introduction device 30.

公开(公告)号：US12036245B2

公开(公告)日：2024-07-16

申请号：US17292298

申请日：2019-10-04

申请人： Koji Tanabe ,  I Peace, Inc.

发明人： Koji Tanabe ,  Kenta Suto

IPC分类号： A61K35/545 ,  A61K8/98 ,  A61P17/14 ,  A61Q19/08

CPC分类号： A61K35/545 ,  A61K8/982 ,  A61P17/14 ,  A61Q19/08

摘要： Provided are a pharmaceutical composition or a pharmaceutical composition raw material, which contains supernatant from a culture medium used during culture to induce pluripotent stem cells.

公开(公告)号：US11518974B2

公开(公告)日：2022-12-06

申请号：US15756031

申请日：2016-08-31

申请人： I PEACE, INC. ,  Koji Tanabe

发明人： Koji Tanabe ,  Brendan Kelly ,  Kenta Suto ,  Hidenori Shimoda ,  Ryoji Hiraide

IPC分类号： C12N5/074 ,  C12M1/36 ,  C12M1/00 ,  C12M1/34 ,  C12M1/33 ,  C12M1/42 ,  C12N5/078 ,  C12M3/00 ,  C12M1/02 ,  C12M1/12

摘要： A stem cell production system provided with a preintroduction cell-feeding solution channel 20 through which a solution containing cells passes, an induction factor-feeding solution mechanism 21 for feeding a pluripotency induction factor to the preintroduction cell-feeding solution channel 20, a factor introduction device 30 connected to the preintroduction cell-feeding solution channel 20 for making cells with induction factor introduced by introducing the pluripotency induction factor into the cells, a cell mass-making device 40 for making multiple cell masses comprising stem cells by culturing the cells with induction factor introduced, and a packaging device 100 for sequentially packaging each of the multiple cell masses.

公开(公告)号：US20220195370A1

公开(公告)日：2022-06-23

申请号：US17645675

申请日：2021-12-22

申请人： I Peace, Inc. ,  FANUC CORPORATION

发明人： Koji Tanabe ,  Ryoji Hiraide ,  Kenta Suto ,  Kazunori Ban ,  Satoshi Kinoshita

IPC分类号： C12M1/00 ,  C12N5/074 ,  C12N15/86 ,  C12M3/00 ,  C12N5/0775

摘要： A cell culture vessel comprising a housing in which a culture chamber is provided. In the housing, at least two holes that connect the outside of the housing and a culture chamber are provided.

公开(公告)号：US11898130B2

公开(公告)日：2024-02-13

申请号：US17269944

申请日：2019-08-20

申请人： I Peace, Inc. ,  FANUC CORPORATION

发明人： Koji Tanabe ,  Ryoji Hiraide ,  Kenta Suto ,  Kazunori Ban ,  Satoshi Kinoshita

IPC分类号： C12M1/12 ,  C12M1/32 ,  C12M1/00

CPC分类号： C12M25/02 ,  C12M23/12 ,  C12M23/34 ,  C12M41/14

摘要： A cell culture equipment comprising a culture component permeable member 10 that is permeable to culture components, a culture vessel 30 that covers one side of the culture component permeable member 10 and holds a cell-containing medium, and a medium holding vessel 40 that covers the other side of the culture component permeable member 10 and holds a medium.