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1.发明申请公开(公告)号：US20060039944A1
公开(公告)日：2006-02-23
申请号：US10920061
申请日：2004-08-17
申请人： Kolazi Narayanan , Jayanti Patel , Paul Taylor , Domingo Jon
发明人： Kolazi Narayanan , Jayanti Patel , Paul Taylor , Domingo Jon
IPC分类号： A01N25/34
摘要： A solid polymeric dispersant composition for water-insoluble actives includes a primary anionic polymer dispersing agent and a co-dispersant which is a vinyl lactam, in a defined weight ratio, and wettable powders, water dispersible granules and tablets thereof, for delivery of actives to a desired site.
摘要翻译： 用于水不溶性活性物质的固体聚合物分散剂组合物包括主要的阴离子聚合物分散剂和以分配的重量比为乙烯基内酰胺的共分散剂，以及可湿性粉剂，水分散性颗粒和片剂，用于将活性物质递送至 一个所需的网站。
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公开(公告)号：US20060045914A1
公开(公告)日：2006-03-02
申请号：US10926510
申请日：2004-08-26
申请人： Kolazi Narayanan , Domingo Jon , Jayanti Patel
发明人： Kolazi Narayanan , Domingo Jon , Jayanti Patel
IPC分类号： A61K9/14
CPC分类号： A61K8/068 , A61K8/556 , A61K9/1075 , A61Q5/12 , A61Q13/00
摘要： A matrix composition for making a stable microemulsion for an active ingredient includes a C8-C18 N-alkyl pyrrolidone with little or no N-methyl pyrrolidone, and a water-insoluble organic solvent soluble therein, preferably more hydrophilic than said C8-C18 alkyl pyrrolidone and with low water solubility.
摘要翻译： 用于制备用于活性成分的稳定微乳液的基质组合物包括具有很少或不含N-甲基吡咯烷酮的C 8 -C 18 N-烷基吡咯烷酮， 可溶于其中的不溶性有机溶剂，优选比所述C 8 -C 18烷基吡咯烷酮更亲水并且具有低水溶性。
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3.发明授权Synergistic matrix composite for making stable microemulsions of active ingredients 有权用于制备稳定的微乳液活性成分的协同基质复合材料公开(公告)号：US08747871B2
公开(公告)日：2014-06-10
申请号：US11540981
申请日：2006-09-28
申请人： Kolazi S. Narayanan , Domingo Jon , Jayanti Patel , Karen Winkowski , Andreas Mitschke , Otto W. Gordon
发明人： Kolazi S. Narayanan , Domingo Jon , Jayanti Patel , Karen Winkowski , Andreas Mitschke , Otto W. Gordon
CPC分类号： A01N25/04 , A61K8/068 , A61K8/922 , A61Q5/02 , C09D5/02 , C11D17/0021 , A01N27/00 , A01N31/08 , A01N53/00 , A01N65/06 , A01N65/36
摘要： What is described herein is a synergistic matrix composite for making a stable microemulsion in water of an active ingredient comprising a first matrix composition including by wt. (a) 5-30% of a C8-C18 N-alkyl pyrrolidone, (b) optionally, 5-60% of a water insoluble organic solvent soluble therein, (c) 30-70% of a non-ionic emulsifier, and (d) 1-15% of an EO/PO/EO copolymer, and, (e) optionally, 1-5% of a surface active buffering agent, e.g. a branched alkyl ethoxylated phosphate ester, a second matrix composition comprising a polar polymeric material, e.g. polyethylene glycol, and/or a neutralized derivatized vegetable oil, e.g. maleated linseed oil, which composite is capable of loading a higher amount of said active than either composition alone.
摘要翻译： 本文描述的是用于在活性成分的水中制备稳定的微乳液的协同性基质复合物，其包含第一基质组合物， （a）5-30％的C 8 -C 18 N-烷基吡咯烷酮，（b）任选的5-60％可溶于其中的水不溶性有机溶剂，（c）30-70％的非离子乳化剂，以及 （d）EO / PO / EO共聚物的1-15％，（e）1-5％的表面活性缓冲剂，例如 支链烷基乙氧基化磷酸酯，包含极性聚合物材料的第二基质组合物，例如。 聚乙二醇和/或中和的衍生植物油，例如， 马来酸亚麻子油，该复合材料能够单独加载比任一组合物更高量的所述活性物质。
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公开(公告)号：US20100260691A1
公开(公告)日：2010-10-14
申请号：US11803108
申请日：2007-05-11
摘要： An aqueous composition containing a hydrophobic material, and, more particularly, a water soluble matrix of a water soluble polymer and a water soluble surfactant, in the form of a complex, for stabilizing the hydrophobic material, as a nanoparticulate dispersion or emulsion. A delivery system for delivering bioactive hydrophobic materials as an aqueous nanoparticle dispersion of a water soluble matrix of polymer and a surfactant.
摘要翻译： 含有疏水性材料的水性组合物，更具体地说，为复合物形式的水溶性聚合物和水溶性表面活性剂的水溶性基质，用于稳定疏水性材料，作为纳米颗粒分散体或乳液。 用于递送生物活性疏水材料作为聚合物和表面活性剂的水溶性基质的水性纳米颗粒分散体的递送系统。
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5.发明申请Synergistic matrix composite for making stable microemulsions of active ingredients 有权用于制备稳定的微乳液活性成分的协同基质复合材料公开(公告)号：US20080081059A1
公开(公告)日：2008-04-03
申请号：US11540981
申请日：2006-09-28
申请人： Kolazi S. Narayanan , Domingo Jon , Jayanti Patel , Karen Winkowski , Andreas Mitschke , Otto W. Gordon
发明人： Kolazi S. Narayanan , Domingo Jon , Jayanti Patel , Karen Winkowski , Andreas Mitschke , Otto W. Gordon
CPC分类号： A01N25/04 , A61K8/068 , A61K8/922 , A61Q5/02 , C09D5/02 , C11D17/0021 , A01N27/00 , A01N31/08 , A01N53/00 , A01N65/06 , A01N65/36
摘要： What is described herein is a synergistic matrix composite for making a stable microemulsion in water of an active ingredient comprising a first matrix composition including by wt. (a) 5-30% of a C8-C18 N-alkyl pyrrolidone, (b) optionally, 5-60% of a water insoluble organic solvent soluble therein, (c) 30-70% of a non-ionic emulsifier, and (d) 1-15% of an EO/PO/EO copolymer, and, (e) optionally, 1-5% of a surface active buffering agent, e.g. a branched alkyl ethoxylated phosphate ester, a second matrix composition comprising a polar polymeric material, e.g. polyethylene glycol, and/or a neutralized derivatized vegetable oil, e.g. maleated linseed oil, which composite is capable of loading a higher amount of said active than either composition alone.
摘要翻译： 本文描述的是用于在活性成分的水中制备稳定的微乳液的协同性基质复合物，其包含第一基质组合物， （a）5-30％的C 8 -C 18 N-烷基吡咯烷酮，（b）任选的5-60％可溶于其中的水不溶性有机溶剂 ，（c）30-70％的非离子乳化剂，和（d）1-15％的EO / PO / EO共聚物，和（e）任选地1-5％的表面活性缓冲剂， 例如 支链烷基乙氧基化磷酸酯，包含极性聚合物材料的第二基质组合物，例如。 聚乙二醇和/或中和的衍生植物油，例如， 马来酸亚麻子油，该复合材料能够单独加载比任一组合物更高量的所述活性物质。
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公开(公告)号：US20100239629A1
公开(公告)日：2010-09-23
申请号：US11496599
申请日：2006-07-31
摘要： A delivery system for delivering bioactive materials as an aqueous nanoparticle dispersion of a water soluble matrix of polyvinylpyrrolidone (PVP) polymer and copolymers thereof, and an anionic surfactant.
摘要翻译： 用于递送生物活性材料的递送系统，作为聚乙烯吡咯烷酮（PVP）聚合物及其共聚物的水溶性基质的水性纳米颗粒分散体和阴离子表面活性剂。
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公开(公告)号：US06740653B2
公开(公告)日：2004-05-25
申请号：US10023013
申请日：2001-12-18
申请人： Kolazi S. Narayanan , Domingo Jon
发明人： Kolazi S. Narayanan , Domingo Jon
IPC分类号： A01N2502
CPC分类号： A61K9/0017 , A01N37/52 , A01N47/36 , A61K9/1075 , A61K31/155 , A01N25/22 , A01N25/04 , A01N2300/00
摘要： This invention relates to the stabilization of o/w microemulsions containing an active aza biocide by addition of an alkaline, water soluble buffering agent in an amount sufficient to adjust the pH to between 6 and 14 and to the use of said o/w microemulsions to control infestations and/or infections when topically applied to livestock or domestic animals.
摘要翻译： 本发明涉及通过加入足以将pH调节至6至14的量的碱性水溶性缓冲剂和使用所述o / w微乳液来稳定含有活性氮杂杀菌剂的o / w微乳液 控制侵染和/或局部应用于家畜或家畜时的感染。
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8.发明授权Aqueous, flowable suspension concentrate of an agriculturally active chemical, and sprayable use formulation thereof 有权农业活性化学品的水性，可流动悬浮浓缩物及其可喷雾使用的制剂
公开(公告)号：US6156803A
公开(公告)日：2000-12-05
申请号：US164541
申请日：1998-09-30
CPC分类号： C08F8/44 , A01N25/04 , A01N25/14 , Y10S514/937 , Y10S514/938
摘要： What is described is an aqueous, flowable suspension concentrate of an agriculturally active chemical having excellent dilution and storage stability, and sprayable aqueous use formulation thereof, containing partially neutralized alkyl vinyl ether-maleic acid half-ester copolymers as dispersing agents therein.
摘要翻译： 所描述的是具有优异的稀释和储存稳定性的农业活性化学品的水性可流动悬浮浓缩物及其可喷雾的含水用制剂，其中含有部分中和的烷基乙烯基醚 - 马来酸半酯共聚物作为分散剂。
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公开(公告)号：US5928992A
公开(公告)日：1999-07-27
申请号：US850792
申请日：1997-05-02
摘要： This invention relates to a solid delivery system (SDS) for active agricultural chemicals, and, more particularly, to a bioenhanced, stable SDS for sulfonyl and sulfamoylurea agricultural chemicals capable of forming aqueous microdispersions or tank mixes thereof suitable for application to a plant site.
摘要翻译： 本发明涉及一种用于活性农药的固体递送系统（SDS），更具体地说，涉及能够形成适用于植物部位的水溶性微分散体或其混合物的磺酰基和氨磺酰脲农药的生物增强稳定的SDS。
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公开(公告)号：US10188100B2
公开(公告)日：2019-01-29
申请号：US13521138
申请日：2011-01-10
IPC分类号： A61K8/06 , A61K47/16 , A01N25/00 , A01N25/02 , A61K8/42 , A61K8/55 , A61K8/86 , A61K9/00 , A61K9/10 , A61K9/107 , A61K47/10 , A61K47/14 , A61K47/20 , A61K47/22 , A61K47/34 , A61Q19/00 , C09K3/00 , A01N37/18
摘要： A matrix composition capable of forming an emulsion/micro-emulsion comprising an emulsifiable matrix, essentially free of alkyl pyrrolidone and alkoxylated alcohol, comprising: (i) a long chain substituted amide; (ii) a surface active agent; and (iii) optionally, an organic diluent.
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