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公开(公告)号：US20070172933A1
公开(公告)日：2007-07-26
申请号：US10549782
申请日：2004-02-16
CPC分类号： C12P7/40 , C12N9/80 , C12N9/86 , C12P41/006
摘要： The invention relates to novel amidases which can be isolated from thermophilic bacteria, in particular from thermophilic Actinomycetes, e.g. Pseudonocardia thermophila, in which the resultant amidases not only have a high temperature stability, but are also distinguished by the enantioselective reaction of a broad substrate spectrum.
摘要翻译： 本发明涉及可以从嗜热细菌，特别是嗜热放线菌（例如细菌）分离的新型酰胺酶。 嗜热假诺卡氏菌，其中所得的酰胺酶不仅具有高温稳定性，而且还通过宽底物光谱的对映选择性反应来区分。
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公开(公告)号：US20080248538A1
公开(公告)日：2008-10-09
申请号：US10598873
申请日：2005-03-14
申请人： Steffen Osswald , Christoph Weckbecker , Klaus Huthmacher , Tatijana Gerasimova , Andrey Novikov , Ludmila Ryabchenko , Alexander Yanenko , Ksenia Egorova
发明人： Steffen Osswald , Christoph Weckbecker , Klaus Huthmacher , Tatijana Gerasimova , Andrey Novikov , Ludmila Ryabchenko , Alexander Yanenko , Ksenia Egorova
摘要： Disclosed herein are cyanide-tolerant nitrile hydratases especially from Pseudomonas putida or Pseudomonas marginalis strains which exhibit increased cyanide tolerance. Also disclosed are methods of preparing amides from nitriles in the presence of cyanides and polynucleotide sequences coding for cyanide-tolerant nitrile hydratases.
摘要翻译： 本文公开的是氰化物耐受性腈水合酶，特别是恶臭假单胞菌（Pseudomonas putida）或边缘假单胞菌（Pseudomonas marginalis）的菌株，其表现出增加的氰化物耐受性。 还公开了在氰化物和编码氰化物耐受性腈水合酶的多核苷酸序列存在下由腈制备酰胺的方法。
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3.发明授权Polynucleotides which code for cyanide-tolerant nitrile hydratase and compositions thereof 有权编码氰化物耐受性腈水合酶的多核苷酸及其组合物公开(公告)号：US07943359B2
公开(公告)日：2011-05-17
申请号：US12539804
申请日：2009-08-12
申请人： Steffen Osswald , Christoph Weckbecker , Klaus Huthmacher , Tatijana Gerasimova , Andrey Novikov , Ludmila Ryabchenko , Alexander Yanenko , Ksenia Egorova
发明人： Steffen Osswald , Christoph Weckbecker , Klaus Huthmacher , Tatijana Gerasimova , Andrey Novikov , Ludmila Ryabchenko , Alexander Yanenko , Ksenia Egorova
摘要： Disclosed herein are cyanide-tolerant nitrile hydratases especially from Pseudomonas putida or Pseudomonas marginalis strains which exhibit increased cyanide tolerance. Also disclosed are methods of preparing amides from nitriles in the presence of cyanides and polynucleotide sequences coding for cyanide-tolerant nitrile hydratases.
摘要翻译： 本文公开的是氰化物耐受性腈水合酶，特别是恶臭假单胞菌（Pseudomonas putida）或边缘假单胞菌（Pseudomonas marginalis）的菌株，其表现出增加的氰化物耐受性。 还公开了在氰化物和编码氰化物耐受性腈水合酶的多核苷酸序列存在下由腈制备酰胺的方法。
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公开(公告)号：US20100261250A1
公开(公告)日：2010-10-14
申请号：US12539804
申请日：2009-08-12
申请人： Steffen Osswald , Christoph Weckbecker , Klaus Huthmacher , Tatijana Gerasimova , Andrey Novikov , Ludmila Ryabchenko , Alexander Yanenko , Ksenia Egorova
发明人： Steffen Osswald , Christoph Weckbecker , Klaus Huthmacher , Tatijana Gerasimova , Andrey Novikov , Ludmila Ryabchenko , Alexander Yanenko , Ksenia Egorova
摘要： Disclosed herein are cyanide-tolerant nitrile hydratases especially from Pseudomonas putida or Pseudomonas marginalis strains which exhibit increased cyanide tolerance. Also disclosed are methods of preparing amides from nitriles in the presence of cyanides and polynucleotide sequences coding for cyanide-tolerant nitrile hydratases.
摘要翻译： 本文公开的是氰化物耐受性腈水合酶，特别是恶臭假单胞菌（Pseudomonas putida）或边缘假单胞菌（Pseudomonas marginalis）的菌株，其表现出增加的氰化物耐受性。 还公开了在氰化物和编码氰化物耐受性腈水合酶的多核苷酸序列存在下由腈制备酰胺的方法。
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公开(公告)号：US07592165B2
公开(公告)日：2009-09-22
申请号：US10598873
申请日：2005-03-14
申请人： Steffen Osswald , Christoph Weckbecker , Klaus Huthmacher , Tatijana Gerasimova , Andrey Novikov , Ludmila Ryabchenko , Alexander Yanenko , Ksenia Egorova
发明人： Steffen Osswald , Christoph Weckbecker , Klaus Huthmacher , Tatijana Gerasimova , Andrey Novikov , Ludmila Ryabchenko , Alexander Yanenko , Ksenia Egorova
摘要： Disclosed herein are cyanide-tolerant nitrile hydratases especially from Pseudomonas putida or Pseudomonas marginalis strains which exhibit increased cyanide tolerance. Also disclosed are methods of preparing amides from nitriles in the presence of cyanides and polynucleotide sequences coding for cyanide-tolerant nitrile hydratases.
摘要翻译： 本文公开的是氰化物耐受性腈水合酶，特别是恶臭假单胞菌（Pseudomonas putida）或边缘假单胞菌（Pseudomonas marginalis）的菌株，其表现出增加的氰化物耐受性。 还公开了在氰化物和编码耐受氰化腈水合酶的多核苷酸序列存在下由腈制备酰胺的方法。
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