公开(公告)号：US20050279928A1

公开(公告)日：2005-12-22

申请号：US11151466

申请日：2005-06-14

申请人： Kunihiko Ohkubo ,  Kiichi Fukui ,  Kazuyoshi Itoh

发明人： Kunihiko Ohkubo ,  Kiichi Fukui ,  Kazuyoshi Itoh

IPC分类号： H01J49/16 ,  H01J49/40 ,  B01D59/44

CPC分类号： H01J49/162 ,  H01J49/0463

摘要： The mass spectrometer according to the present invention includes a light source for emitting pulse light including a plurality of wavelengths; an ionizer for ionizing molecules of a sample by irradiating the light from the light source to the sample; and a mass analyzer for separating ions ionized in the ionizer according to their mass to charge ratios. For the light source, one including a plurality of ultrashort pulse laser sources each emitting a wavelength different from others, and one emitting ultrashort pulse light including plural wavelengths ranging from the visible region to the infrared region generated by dispersing an ultrashort pulse light with continuous (white) spectrum can be used. Pulse lights having plural wavelengths ranging from near infrared to the ultraviolet region respectively share the role; i.e., one of them vaporizes the sample without fragmenting it, and another ionizes the vaporized sample with the single-photon process or two-photon (or multi-photon) process. This enables ionization of protein complexes as a whole contained in the sample, and enables mass analyses of them.

摘要翻译： 根据本发明的质谱仪包括用于发射包括多个波长的脉冲光的光源; 电离器，用于通过将来自光源的光照射到样品上来使样品的分子离子化; 以及质量分析器，用于根据电离质量与电离比分离在离子发生器中离子化的离子。 对于光源，包括多个发射不同于其他波长的超短脉冲激光源的光源，以及一个发射包括从可见光区域到红外区域的多个波长的超短脉冲光，通过分散具有连续的超短脉冲光 白色）光谱。 分别具有从近红外到紫外线区域的多个波长的脉冲光共同作用; 即，其中一个使样品蒸发而不使其分裂，另一个使用单光子过程或双光子（或多光子）过程将蒸发的样品电离。 这使得能够将样品中包含的蛋白质复合物电离，并且能够进行质量分析。

公开(公告)号：US07342223B2

公开(公告)日：2008-03-11

申请号：US11151466

申请日：2005-06-14

申请人： Kunihiko Ohkubo ,  Kiichi Fukui ,  Kazuyoshi Itoh

发明人： Kunihiko Ohkubo ,  Kiichi Fukui ,  Kazuyoshi Itoh

IPC分类号： B01D59/44

CPC分类号： H01J49/162 ,  H01J49/0463

摘要： The mass spectrometer according to the present invention includes a light source for emitting pulse light including a plurality of wavelengths; an ionizer for ionizing molecules of a sample by irradiating the light from the light source to the sample; and a mass analyzer for separating ions ionized in the ionizer according to their mass to charge ratios. For the light source, one including a plurality of ultrashort pulse laser sources each emitting a wavelength different from others, and one emitting ultrashort pulse light including plural wavelengths ranging from the visible region to the infrared region generated by dispersing an ultrashort pulse light with continuous (white) spectrum can be used. Pulse lights having plural wavelengths ranging from near infrared to the ultraviolet region respectively share the role; i.e., one of them vaporizes the sample without fragmenting it, and another ionizes the vaporized sample with the single-photon process or two-photon (or multi-photon) process. This enables ionization of protein complexes as a whole contained in the sample, and enables mass analyses of them.

摘要翻译： 根据本发明的质谱仪包括用于发射包括多个波长的脉冲光的光源; 电离器，用于通过将来自光源的光照射到样品上来使样品的分子离子化; 以及质量分析器，用于根据电离质量与电离比分离在离子发生器中离子化的离子。 对于光源，包括多个发射不同于其他波长的超短脉冲激光源的光源，以及一个发射包括从可见光区域到红外区域的多个波长的超短脉冲光，通过分散具有连续的超短脉冲光 白色）光谱。 分别具有从近红外到紫外线区域的多个波长的脉冲光共同作用; 即，其中一个使样品蒸发而不使其分裂，另一个使用单光子过程或双光子（或多光子）过程将蒸发的样品电离。 这使得能够将样品中包含的蛋白质复合物电离，并且能够进行质量分析。

公开(公告)号：US06864975B2

公开(公告)日：2005-03-08

申请号：US10310032

申请日：2002-12-05

申请人： Kazuyoshi Itoh ,  Kiichi Fukui ,  Kunihiko Ohkubo

发明人： Kazuyoshi Itoh ,  Kiichi Fukui ,  Kunihiko Ohkubo

IPC分类号： G01J3/10 ,  G01J3/44 ,  G01N21/01 ,  G01N21/64 ,  G01J3/18

CPC分类号： G01J3/4406 ,  G01J3/0229 ,  G01J3/10 ,  G01J2003/1213 ,  G01N21/645 ,  G01N2021/6419

摘要： The present invention proposes a method of and system for analyzing samples (particularly, bio-samples), wherein the continuous spectrum white light pulse generated from an ultra-short optical pulse is used in a simple manner. By a system according to the invention, continuous spectrum white light pulses generated by converging ultra-short optical pulses on a point in a transparent substance 23 are dispersed into a spectrum of light by a dispersing element 25, and a plurality of objective wavelength components are separately selected by small reflection mirrors 37, masked mirrors or the like. The selected objective wavelength components are combined by the dispersing element 25 into a composite optical pulse containing the objective wavelength components. The composite optical pulse is irradiated onto the bio-sample 28 or other samples, whereby only the desired fluorescent substances are excited by the objective wavelength components corresponding to them. The selected objective wavelength components may preferably have different light path lengths. By this construction, the component optical pulses corresponding to the objective wavelengths in the composite optical pulse are separated from each other, so that the noise due to the interference of different wavelength components is prevented.

摘要翻译： 本发明提出了一种用于分析样品（特别是生物样品）的方法和系统，其中以简单的方式使用从超短光脉冲产生的连续光谱白光脉冲。 通过根据本发明的系统，通过在透明物质23中的点聚焦超短光脉冲而产生的连续光谱白光脉冲通过分散元件25分散到光谱中，并且多个目标波长分量是 通过小反射镜37分别选择掩模镜等。 所选择的目标波长分量由分散元件25组合成包含目标波长分量的复合光脉冲。 将复合光脉冲照射到生物样品28或其他样品上，由此只有所需的荧光物质被与它们相对应的目标波长成分激发。 所选择的目标波长分量可以优选地具有不同的光路长度。 通过这种结构，与复合光脉冲中的目标波长相对应的分量光脉冲彼此分离，从而防止了由于不同波长分量的干扰引起的噪声。

公开(公告)号：US08629980B2

公开(公告)日：2014-01-14

申请号：US13375388

申请日：2010-06-02

申请人： Yasuyuki Ozeki ,  Kazuyoshi Itoh ,  Fumihiro Dake ,  Kiichi Fukui ,  Shinichiro Kajiyama ,  Yuma Kitagawa ,  Norihiko Nishizawa ,  Kazuhiko Sumimura

发明人： Yasuyuki Ozeki ,  Kazuyoshi Itoh ,  Fumihiro Dake ,  Kiichi Fukui ,  Shinichiro Kajiyama ,  Yuma Kitagawa ,  Norihiko Nishizawa ,  Kazuhiko Sumimura

IPC分类号： G01J3/44

CPC分类号： G01J3/4412 ,  G01N21/65 ,  G02B21/06 ,  G02B21/365

摘要： The invention provides an optical microscope that prevents an increase in the complexity of the light source system and is equipped with optics readily capable of adequate operation even when the modulation frequency is increased in order to reduce the impact of the intensity noise of the laser, etc. This optical microscope 100 irradiates a sample 6 with a first train of optical pulses having a first optical frequency, which is generated by a first light source, and a second train of optical pulses having a second optical frequency, which is temporally synchronized with the first train of optical pulses and is generated by a second light source, and detects light scattered from the sample 6. The repetition frequency of the train of optical pulses generated by the first light source is an integral sub-multiple of the repetition frequency of the train of optical pulses generated by the second light source.

摘要翻译： 本发明提供了一种光学显微镜，其防止光源系统的复杂性的增加，并且配备有即使当增加调制频率以便减少激光器的强度噪声的影响等时容易进行适当操作的光学器件 该光学显微镜100照射具有由第一光源产生的具有第一光学频率的第一列光脉冲的样品6和具有与第二光频同步的第二光学频率的第二光脉冲序列 第一光脉冲串，并由第二光源产生，并且检测从样品6散射的光。由第一光源产生的光脉冲序列的重复频率是该第一光源的重复频率的整数倍 由第二光源产生的光脉冲序列。

公开(公告)号：US20120140217A1

公开(公告)日：2012-06-07

申请号：US13375388

申请日：2010-06-02

申请人： Yasuyuki Ozeki ,  Kazuyoshi Itoh ,  Fumihiro Dake ,  Kiichi Fukui ,  Shinichiro Kajiyama ,  Yuma Kitagawa ,  Norihiko Nishizawa ,  Kazuhiko Sumimura

发明人： Yasuyuki Ozeki ,  Kazuyoshi Itoh ,  Fumihiro Dake ,  Kiichi Fukui ,  Shinichiro Kajiyama ,  Yuma Kitagawa ,  Norihiko Nishizawa ,  Kazuhiko Sumimura

IPC分类号： G01N21/65

CPC分类号： G01J3/4412 ,  G01N21/65 ,  G02B21/06 ,  G02B21/365

摘要： The invention provides an optical microscope that prevents an increase in the complexity of the light source system and is equipped with optics readily capable of adequate operation even when the modulation frequency is increased in order to reduce the impact of the intensity noise of the laser, etc. This optical microscope 100 irradiates a sample 6 with a first train of optical pulses having a first optical frequency, which is generated by a first light source, and a second train of optical pulses having a second optical frequency, which is temporally synchronized with the first train of optical pulses and is generated by a second light source, and detects light scattered from the sample 6. The repetition frequency of the train of optical pulses generated by the first light source is an integral sub-multiple of the repetition frequency of the train of optical pulses generated by the second light source.

摘要翻译： 本发明提供了一种光学显微镜，其防止光源系统的复杂性的增加，并且配备有即使当增加调制频率以便减少激光器的强度噪声的影响等时容易进行适当操作的光学器件 该光学显微镜100照射具有由第一光源产生的具有第一光学频率的第一列光脉冲的样品6和具有与第二光频同步的第二光学频率的第二光脉冲序列 第一光脉冲串，并由第二光源产生，并且检测从样品6散射的光。由第一光源产生的光脉冲序列的重复频率是该第一光源的重复频率的整数倍 由第二光源产生的光脉冲序列。

公开(公告)号：US07224255B2

公开(公告)日：2007-05-29

申请号：US10921856

申请日：2004-08-20

申请人： Yasuhiro Uehara ,  Kazuyoshi Itoh

发明人： Yasuhiro Uehara ,  Kazuyoshi Itoh

IPC分类号： H01H85/143 ,  H01H85/147

CPC分类号： H01H37/761

摘要： An overheat protection device for a movable body surface includes a thermal fuse having a fuse element which melts at a predetermined temperature, bridges electrodes in a pair and melts at a temperature equal to or higher than the predetermined temperature to break an electrical connection between the pair of electrodes, and a pair of long elastic bodies, to each of which one of the electrodes is electrically connected at an end or its periphery of the elastic body through a lead. At least one of pairs of upper surfaces and lower surfaces of the elastic bodies are spatially on a same plane.

摘要翻译： 用于可移动体表面的过热保护装置包括具有在预定温度下熔化的熔丝元件的热熔丝，桥接一对电极并在等于或高于预定温度的温度下熔化以破坏该对之间的电连接 的电极和一对长的弹性体，其中每个电极通过引线在弹性体的端部或其周边处电连接。 弹性体的至少一对上表面和下表面在空间上在同一平面上。

公开(公告)号：US20130088770A1

公开(公告)日：2013-04-11

申请号：US13643367

申请日：2011-04-26

申请人： Norihiko Nishizawa ,  Yasuyuki Ozeki ,  Kazuyoshi Itoh

发明人： Norihiko Nishizawa ,  Yasuyuki Ozeki ,  Kazuyoshi Itoh

IPC分类号： G02F1/39 ,  H01S3/067

CPC分类号： G02F1/395 ,  G02B6/02247 ,  G02F1/3513 ,  H01S3/067

摘要： The present invention provides a method for narrowing a spectral width that can also be adapted to an ultrashort optical pulse emitted from a wavelength tunable light source, and that can provide an output optical pulse with a narrow spectral width and a low noise component, and an optical element and a light source device that use the method for narrowing a spectral width. The method includes using an optical waveguide member (2) to cause a soliton effect in an input optical pulse (1) within the optical waveguide member (2), thereby narrowing a spectral width of the input optical pulse (1) to provide an output optical pulse (3), the optical waveguide member (2) having dispersion characteristics such that the average of a second-order dispersion value (β2) with respect to the input optical pulse (1) is negative, and the absolute value of the second-order dispersion value (β2) increases in a propagation direction of the input optical pulse (1).

摘要翻译： 本发明提供了一种缩小光谱宽度的方法，该方法也可以适用于从波长可调谐光源发射的超短光脉冲，并且可以提供具有窄光谱宽度和低噪声分量的输出光脉冲，以及 光学元件和使用这种缩小光谱宽度的方法的光源装置。 该方法包括使用光波导构件（2）在光波导构件（2）内的输入光脉冲（1）中产生孤子效应，从而使输入光脉冲（1）的光谱宽度变窄以提供输出 光脉冲（3），具有使二阶色散值（＆bgr; 2）相对于输入光脉冲（1）的平均值为负的色散特性的光波导元件（2），绝对值 二阶色散值（＆bgr; 2）在输入光脉冲（1）的传播方向上增加。

公开(公告)号：US20070047991A1

公开(公告)日：2007-03-01

申请号：US11391337

申请日：2006-03-29

申请人： Kazuyoshi Itoh ,  Yasutaka Naito ,  Motofumi Baba ,  Hideaki Ohhara

发明人： Kazuyoshi Itoh ,  Yasutaka Naito ,  Motofumi Baba ,  Hideaki Ohhara

IPC分类号： G03G15/20

CPC分类号： G03G15/2064 ,  G03G15/2032 ,  G03G15/2039 ,  G03G2215/2016 ,  G03G2215/2035

摘要： A fixing apparatus for fixing an unfixed image on a recording material includes: a heating member having a conductive layer, that is rotatably provided; a pressure member that is rotatably provided and that is brought into press-contact with the heating member, thereby forms a fixing nip part to pass the recording material between the pressure member and the heating member; a heating unit that performs induction heating on the heating member via the conductive layer; a driving unit that rotates the heating member; and an attachment/separation unit that attaches or separates the heating member to/from the pressure member.

摘要翻译： 用于将未定影图像固定在记录材料上的定影装置包括：具有可旋转地设置的导电层的加热构件; 压力构件，其被可旋转地设置并与加热构件压接，从而形成定影夹持部，以使压力构件和加热构件之间的记录材料通过; 加热单元，其经由所述导电层对所述加热构件进行感应加热; 使所述加热部件旋转的驱动部; 以及附加/分离单元，其将加热构件附接或分离到压力构件。

公开(公告)号：US20070047983A1

公开(公告)日：2007-03-01

申请号：US11391338

申请日：2006-03-29

申请人： Kazuyoshi Itoh ,  Yasuhiro Uehara

发明人： Kazuyoshi Itoh ,  Yasuhiro Uehara

IPC分类号： G03G15/20

CPC分类号： G03G15/2039 ,  G03G15/80

摘要： A heating apparatus includes: an exciting coil provided in close vicinity of a heated body having a conductive layer; a capacitor connected serially or in parallel with the exciting coil; a switching element that generates a high frequency current by turning on/off a direct current and that supplies the high frequency current to the exciting coil and the capacitor; a specifying unit that specifies an electric value to be supplied to the exciting coil; an output unit that outputs, to the switching element, a driving signal to turn on the switching element for a period determined in correspondence with the specified electric value; a voltage detection unit that detects a flyback voltage value generated in a resonance circuit including the exciting coil and the capacitor; and an abnormality detection unit that detects an abnormality in the heated body based on the detected flyback voltage value.

摘要翻译： 一种加热装置，包括：设置在具有导电层的被加热体附近的励磁线圈; 与励磁线圈串联或并联连接的电容器; 开关元件，其通过接通/断开直流电而产生高频电流，并将高频电流提供给励磁线圈和电容器; 指定单元，其指定要提供给所述励磁线圈的电值; 输出单元，向所述开关元件输出驱动信号，以将所述开关元件接通一定时间，所述周期与所述指定电值相对应; 电压检测单元，其检测在包括所述励磁线圈和所述电容器的谐振电路中产生的回扫电压值; 以及异常检测单元，其基于检测到的反激电压值来检测加热体的异常。

公开(公告)号：US06969820B2

公开(公告)日：2005-11-29

申请号：US10921848

申请日：2004-08-20

申请人： Ken-ichi Hayashi ,  Kazuyoshi Itoh

发明人： Ken-ichi Hayashi ,  Kazuyoshi Itoh

IPC分类号： B41J3/00 ,  B23K26/00 ,  B41M5/26 ,  G02B5/18

CPC分类号： B41M5/262 ,  B23K26/361 ,  B23K2101/007 ,  C03C23/0025 ,  G01N21/4788 ,  G02B5/1857 ,  G02B5/1871 ,  G03H2001/0484 ,  Y10S430/146

摘要： A marking method is provided which permits an easy detecting of the presence of a mark without using a specific reading apparatus, and is capable of avoiding a damage as well as a strength deterioration of an object material. The marking method comprises: preparing a marking object; converging, into the marking object, a laser beam having a wave length range so chosen that the laser beam can transmit through a material forming the marking object, and then effecting a multiple photon absorption; and moving a converging position of the laser beam, in a manner such that an area, whose refractive index is changed due to the multiple photon absorption, can form a diffraction pattern capable of diffracting a visible light.

摘要翻译： 提供了一种标记方法，其允许在不使用特定读取装置的情况下容易地检测标记的存在，并且能够避免对象材料的损伤以及强度劣化。 标记方法包括：准备标记对象; 会聚到标记物体中，具有如此选择的波长范围的激光束，使得激光束可以通过形成标记物体的材料透射，然后实现多光子吸收; 并且以使得由于多光子吸收而折射率改变的区域可以形成能够衍射可见光的衍射图案的方式来移动激光束的会聚位置。