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公开(公告)号：US5569928A
公开(公告)日：1996-10-29
申请号：US166494
申请日：1993-12-14
CPC分类号： A61M1/3681 , A61M1/3683 , A61M1/3693
摘要： Light arrays for use in systems for separating and irradiating blood are disclosed. In accordance with the present invention, the light array has one or more bulbs with electrical connecting leads and first and second support members connected to the bulbs. The second support member preferably includes a connector for receiving the electrical leads. The support members preferably define an end surface and an interior surface, wherein the support members are disposed adjacent the bulbs so the end surfaces are opposed to define a channel, providing a space where tubing carrying blood or other fluids can be disposed without interfering with the array. The bulbs are most preferably attached to the support members using flexible self-locking straps, and in embodiments using two or more bulbs, the bulbs are also preferably held together by one or more straps. Improved mounting systems for connecting the array to the instrument by one or more spring mounts are also disclosed. In certain preferred embodiments, one of the support members is a circuit board and includes a microcircuit for controlling the operation of the array using a clock/timer circuit for determining a total time of activation for the array, whereby upon reaching a predetermined value of the total time of activation, the clock/timer circuit disables the light array. Thus, methods of controlling the output of an array of bulbs are also disclosed.
摘要翻译： 公开了用于分离和照射血液的系统中的光阵列。 根据本发明，光阵列具有一个或多个具有电连接引线的灯泡和连接到灯泡的第一和第二支撑构件。 第二支撑构件优选地包括用于接收电引线的连接器。 支撑构件优选地限定端表面和内表面，其中支撑构件邻近灯泡设置，使得端表面相对以限定通道，从而提供容纳血液或其它流体的管道可以在不干扰 数组。 灯泡最优选地使用柔性自锁带附接到支撑构件，并且在使用两个或更多个灯泡的实施例中，灯泡也优选地通过一个或多个带固定在一起。 还公开了用于通过一个或多个弹簧座将阵列连接到仪器的改进的安装系统。 在某些优选实施例中，支撑构件之一是电路板，并且包括用于使用用于确定阵列的激活的总时间的时钟/定时器电路来控制阵列的操作的微电路，由此在达到预定值 总共激活时间，时钟/定时器电路禁用光阵列。 因此，还公开了控制灯泡阵列的输出的方法。
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公开(公告)号：US4921473A
公开(公告)日：1990-05-01
申请号：US305339
申请日：1989-02-02
申请人： Kyu H. Lee , Livingston B. Morris
发明人： Kyu H. Lee , Livingston B. Morris
CPC分类号： A61M1/3681 , A61M1/3683 , A61M1/3693 , A61M1/3696 , B04B5/0442 , B04B2005/0464
摘要： A multicomponent fluid separation and irradiation system is described containing a centrifuge drum and a source of radiant energy located within the drum. In a first embodiment a disposable rigid separation/irradiation chamber is provided with a cylindrical outer compartment located within the drum and opposing the radiant energy source. Whole blood is supplied to the chamber through a dynamic seal located at the center of the chamber. As the chamber is rotated, blood is separated so that energy from the source passes through the inner wall of the chamber and the separated plasma layer to irradiate the buffy coat layer. In a second embodiment, one or both of the walls of the outer compartment of the chamber are flexible so that the chamber will expand as blood is pumped in and will collapse as blood is pumped out.
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公开(公告)号：US4028252A
公开(公告)日：1977-06-07
申请号：US583648
申请日：1975-06-04
申请人： Livingston B. Morris
发明人： Livingston B. Morris
IPC分类号： A61M20060101 , A61M1/22 , B01D20060101 , B01D61/24 , B01D61/32 , B01D63/14 , B65H45/12 , G01N13/04 , B01D31/00
CPC分类号： B01D61/28 , B01D63/14 , B01D2313/04 , B01D2313/14
摘要： A support material is fed through mating elements which emboss transverse score lines thereon to form an accordion fold in the material. A single thickness of the folded support material is then interleaved with a permeable membrane and sealed in a housing to form a compact inexpensive flat plate dialyzer. Longitudinal channels are formed in the support material which materially improve distribution of fluids within the dialyzer.
摘要翻译： 支撑材料通过配合元件进给，该配合元件在其上压花横向刻痕线以在材料中形成折叠折叠。 然后将折叠的支撑材料的单一厚度与可渗透膜交错并密封在壳体中以形成紧凑廉价的平板透析器。 在支撑材料中形成纵向通道，其实质上改善透析器内流体的分布。
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公开(公告)号：US06491656B1
公开(公告)日：2002-12-10
申请号：US08975688
申请日：1997-11-21
申请人： Livingston B. Morris
发明人： Livingston B. Morris
IPC分类号： A61M3500
CPC分类号： A61M1/3681 , A61M1/303 , A61M1/3621 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3683 , A61M1/3693 , A61M2202/0415 , A61M2205/125 , A61M2205/128 , A61M2205/7545
摘要： An apparatus controls movement of fluids during an extracorporeal blood treatment session. A hollow cassette enclosure has a plurality of fluid input ports for receiving fluids into the enclosure and a plurality of fluid output ports for expelling fluids from the enclosure. Internal fluid passageways disposed within the hollow enclosure are provided for coupling together the fluid input ports, and the fluid output ports. At least one internal valve is disposed within the hollow enclosure for controlling movement of the fluid within the hollow enclosure. A filter is integrated into the cassette to filter the blood passing therethrough.
摘要翻译： 一种装置控制在体外血液治疗期间流体的运动。 中空的盒式机壳具有多个用于将流体接收到外壳中的流体输入端口和用于从外壳排出流体的多个流体输出端口。 设置在中空外壳内的内部流体通道用于将流体输入端口和流体输出端口联接在一起。 至少一个内部阀设置在中空外壳内，用于控制中空外壳内流体的运动。 将过滤器集成到盒中以过滤穿过其中的血液。
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公开(公告)号：US5951509A
公开(公告)日：1999-09-14
申请号：US971879
申请日：1997-11-19
申请人： Livingston B. Morris
发明人： Livingston B. Morris
CPC分类号： A61M1/3681 , A61M1/303 , A61M1/3683 , A61M1/3643
摘要： Apparatus for treating human blood by irradiation. Exposure of a human blood product sample can be optimized by displacing a contiguous, self-contained arrangement, such as a bag member, while radiation is being emitted towards the contiguous, self-contained arrangement, and by maintaining a substantially constant distance between the radiation source and the at least one blood product held in the contiguous, self-contained arrangement. Also proposed is an arrangement in which at least a portion of the radiation source is displaced while radiation is being emitted towards the contiguous, self-contained arrangements holding the blood products in question. Further, an arrangement for cooling the radiation source is contemplated.
摘要翻译： 用于通过照射处理人血液的装置。 人类血液制品样品的暴露可以通过移动邻近的独立布置（例如袋状构件）而被优化，同时辐射朝向相邻的独立布置发射，并且通过在辐射之间保持基本上恒定的距离 来源和所述至少一种血液制品保持在相邻的，独立的装置中。 还提出了一种布置，其中当辐射被朝向保持所讨论的血液制品的连续的独立装置发射时，辐射源的至少一部分被移位。 此外，考虑了用于冷却辐射源的装置。
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公开(公告)号：US5921951A
公开(公告)日：1999-07-13
申请号：US974200
申请日：1997-11-19
申请人： Livingston B. Morris
发明人： Livingston B. Morris
CPC分类号： A61M1/3681 , A61M1/1041 , A61M1/106 , A61M1/1062 , A61M1/3683 , A61M5/14224 , F04B43/067 , F04B53/1067 , A61M2205/053 , A61M5/14216
摘要： An apparatus for pumping fluid at a steady rate. A first drive chamber having a movable outer surface, and a second drive chamber having a movable outer surface are provided. The apparatus further includes a block having a plurality of internal passages including a first passage for receiving the fluid into the block and a second passage for discharging the fluid from the block at the steady rate. The block has first and second internal chambers which are in fluid connection with the first and second passages. The first internal chamber has a first flexible surface for mating with the movable outer surface of the first drive chamber, and the second internal chamber has a second flexible surface for mating with the movable outer surface of the second drive chamber. At least one actuator is provided for applying positive pressure to the first flexible surface while simultaneously applying negative pressure to the second flexible surface and for applying negative pressure to the first flexible surface while simultaneously applying positive pressure to the second flexible surface. The actuator is respectively coupled to the first and second flexible surfaces by the first and second drive chambers.
摘要翻译： 用于以稳定的速率泵送流体的装置。 提供具有可移动外表面的第一驱动室和具有可移动外表面的第二驱动室。 该装置还包括具有多个内部通道的块，该多个内部通道包括用于将流体接收到该块中的第一通道和用于以稳定速率从该块排出流体的第二通道。 该块具有与第一和第二通道流体连接的第一和第二内部室。 第一内室具有用于与第一驱动室的可移动外表面配合的第一柔性表面，并且第二内室具有用于与第二驱动室的可移动外表面配合的第二柔性表面。 提供至少一个致动器用于向第一柔性表面施加正压力，同时向第二柔性表面施加负压并且向第一柔性表面施加负压，同时向第二柔性表面施加正压力。 致动器分别通过第一和第二驱动室联接到第一和第二柔性表面。
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公开(公告)号：US5308309A
公开(公告)日：1994-05-03
申请号：US996298
申请日：1992-12-23
申请人： Livingston B. Morris
发明人： Livingston B. Morris
CPC分类号： B04B7/00
摘要： An improved apparatus for automatically retaining a removable chamber during operation, in a system for separating and irradiating multi-component fluids. A clamp arm that having two ends is provided: the first acts as a securing means, the second contains the clamp arm center of mass. The clamp arm is pivoted on the rotating chuck near the interface of the rotating chuck interior and the removable chamber exterior. The pivot allows for rotation of the clamp arm about the pivot, the pivot being located between the first end with the securing means and the second end containing the center of mass. When the chuck is rotating, the end of the clamp arm containing the center of mass rotates outward, causing the clamp arm securing means to pivot above the removable chamber thereby securing it in place.
摘要翻译： 一种用于在操作期间自动保持可拆卸室的改进的装置，用于分离和照射多组分流体的系统。 提供具有两端的夹持臂：第一个作为固定装置，第二个夹持臂包括夹紧臂的质心。 夹持臂在旋转卡盘附近枢转，靠近旋转卡盘内部和可拆卸室外部的界面。 枢轴允许夹持臂围绕枢轴旋转，枢轴位于具有固定装置的第一端和包含质心的第二端之间。 当卡盘旋转时，包含质心的夹臂的端部向外转动，使得夹紧臂固定装置在可移除的腔室上方枢转，从而将其固定就位。
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公开(公告)号：USD298567S
公开(公告)日：1988-11-15
申请号：US838042
申请日：1986-02-27
申请人： Livingston B. Morris
设计人： Livingston B. Morris
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