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公开(公告)号：US09897920B2
公开(公告)日：2018-02-20
申请号：US14645009
申请日：2015-03-11
发明人： Yunhee Ku , Moosub Kim , Yongju Yang , Seung Yeon Song , Kang Sun Lee , Hyun Chul Yoon , Yong Duk Han , Yoo Min Park
CPC分类号： G03F7/2002 , G01N21/78 , G01N2400/00 , G03F7/027
摘要： The present disclosure relates to a sensor for detecting saccharide and manufacturing method thereof and detection method of glycated hemoglobin using the same wherein the sensor for detecting saccharide includes a reactive layer synthesized with hydrogel having a boronic acid-modified 3D mesh structure. A selective and sensitive detection of the glycated protein including glucose or glycated hemoglobin (HbA1c) in blood through high level of signal may be enabled, and the durability of the sensor for detecting saccharide may be enhanced.
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公开(公告)号：US12117387B2
公开(公告)日：2024-10-15
申请号：US18007348
申请日：2021-07-28
发明人： Hyun Chul Yoon , Jae-Ho Kim , Ka Ram Kim
IPC分类号： G01N21/47 , G01N15/1434 , G01N21/51 , G01N33/483
CPC分类号： G01N15/1434 , G01N21/51 , G01N33/4833
摘要： The present invention provides a cell measurement device and method in which retroreflective particles are introduced to measure cells, and thus, an optical signal is obtained without fixing of life activity of cells and performing a separate staining process. An example of the use of retroreflection-based cytometry is evaluation of cell migration. The cells capture the retroreflective particles during cell migration or growth, and migrate in a state that the particles are captured in the cell or bind to the cells. The migrated cells are observed in a form of bright dots inside the cells under irradiation of white light as a non-spectroscopic light source to the cells in the retroreflective optical system. The number of bright spots is counted, and thus, the number of cells and the presence thereof thus can be easily measured based on an image.
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