公开(公告)号：US20170218095A1

公开(公告)日：2017-08-03

申请号：US15453750

申请日：2017-03-08

Applicant: LIFE TECHNOLOGIES AS

Inventor： Grete MODAHL ,  Geir FONNUM ,  Astrid MOLTEBERG ,  Silje LIEN ,  Nini KJUS

IPC: C08F2/22 ,  C08J9/20

CPC classification number: C08F2/22 ,  C08F8/30 ,  C08F12/08 ,  C08F212/36 ,  C08F257/02 ,  C08F2800/20 ,  C08J3/128 ,  C08J9/18 ,  C08J9/20 ,  C08J2325/08 ,  C12N11/08 ,  Y10T428/2982 ,  Y10T428/2991 ,  Y10T428/2998 ,  C08F212/08

Abstract: This invention relates to monodisperse cross-linked polymer particles, comprising particles with a substantially smooth outer surface and an average diameter of less than 1 μm, wherein the particles are solid or porous, and wherein the coefficient of variation (CV) % of the particles, when measured by CPS disk centrifugation analysis, is less than 15%. These monodisperse cross-linked polymer particles may comprise magnetic material and are useful in various application. This invention also relates to monodisperse polymer particles for use as seed particles in the Ugelstad process.

公开(公告)号：US20180163255A1

公开(公告)日：2018-06-14

申请号：US15891535

申请日：2018-02-08

Applicant: LIFE TECHNOLOGIES AS

Inventor： Darren ELLIS ,  Geir FONNUM ,  Nini KJUS

IPC: C12Q1/6806 ,  C12N15/10

CPC classification number: C12Q1/6806 ,  C12N15/1006 ,  C12N15/1013

Abstract: A method for processing a nucleic acid, in which the nucleic acid is exposed to an aqueous medium which includes a polyol in sufficient proportion for at least a portion of the nucleic acid to enter or remain in an extra-solution phase. Thus, a polyol may be used to bind a nucleic acid which is in solution to a solid support or to wash a nucleic acid on a solid support whilst maintaining it on the support. The polyol may for example be a C2-C10 alkanediol.

公开(公告)号：US20170204398A1

公开(公告)日：2017-07-20

申请号：US15431678

申请日：2017-02-13

Applicant: LIFE TECHNOLOGIES AS

Inventor： Darren ELLIS ,  Geir FONNUM ,  Nini KJUS

IPC: C12N15/10 ,  C12Q1/68

CPC classification number: C12Q1/6806 ,  C12N15/1006 ,  C12N15/1013

Abstract: A method for processing a nucleic acid, in which the nucleic acid is exposed to an aqueous medium which includes a polyol in sufficient proportion for at least a portion of the nucleic acid to enter or remain in an extra-solution phase. Thus, a polyol may be used to bind a nucleic acid which is in solution to a solid support or to wash a nucleic acid on a solid support whilst maintaining it on the support. The polyol may for example be a C2-C10 alkanediol.